DE69628194D1 - Verfahren zum nachweis von verbindungen die bestimmte zielmoleküle binden - Google Patents

Verfahren zum nachweis von verbindungen die bestimmte zielmoleküle binden

Info

Publication number
DE69628194D1
DE69628194D1 DE69628194T DE69628194T DE69628194D1 DE 69628194 D1 DE69628194 D1 DE 69628194D1 DE 69628194 T DE69628194 T DE 69628194T DE 69628194 T DE69628194 T DE 69628194T DE 69628194 D1 DE69628194 D1 DE 69628194D1
Authority
DE
Germany
Prior art keywords
target molecules
specific target
target
binding specific
compounds binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69628194T
Other languages
English (en)
Other versions
DE69628194T2 (de
Inventor
Howard Benjamin
Mark A Findeis
L Gefter
Gary Musso
R Signer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Praecis Pharmaceuticals Inc
Original Assignee
Praecis Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Praecis Pharmaceuticals Inc filed Critical Praecis Pharmaceuticals Inc
Publication of DE69628194D1 publication Critical patent/DE69628194D1/de
Application granted granted Critical
Publication of DE69628194T2 publication Critical patent/DE69628194T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DE69628194T 1995-12-18 1996-12-18 Verfahren zum nachweis von verbindungen die bestimmte zielmoleküle binden Expired - Fee Related DE69628194T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US57378695A 1995-12-18 1995-12-18
US573786 1995-12-18
PCT/US1996/020561 WO1997022617A1 (en) 1995-12-18 1996-12-18 Methods for identifying compounds that bind to a target

Publications (2)

Publication Number Publication Date
DE69628194D1 true DE69628194D1 (de) 2003-06-18
DE69628194T2 DE69628194T2 (de) 2004-04-01

Family

ID=24293389

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69628194T Expired - Fee Related DE69628194T2 (de) 1995-12-18 1996-12-18 Verfahren zum nachweis von verbindungen die bestimmte zielmoleküle binden

Country Status (12)

Country Link
US (4) US20030100007A1 (de)
EP (2) EP1283212A1 (de)
JP (1) JP2000502897A (de)
AT (1) ATE240347T1 (de)
AU (1) AU1430297A (de)
CA (1) CA2238995A1 (de)
DE (1) DE69628194T2 (de)
DK (1) DK0868427T3 (de)
ES (1) ES2200084T3 (de)
HK (1) HK1016194A1 (de)
PT (1) PT868427E (de)
WO (1) WO1997022617A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6326155B1 (en) * 1995-03-20 2001-12-04 Dyax Corp. Engineering affinity ligands for macromolecules
GB9717652D0 (en) * 1997-08-20 1997-10-22 Nycomed Imaging As Method
DE69806066T2 (de) 1997-11-07 2003-02-06 Conjuchem Inc Affinitätsmarkierer für menschliches serum albumin
EP1199566B1 (de) * 1997-11-07 2008-08-27 ConjuChem Biotechnologies Inc. Methoden zum Screening von Affinitätsmarker-Bibliotheken
GB9809776D0 (en) 1998-05-07 1998-07-08 Nycomed Imaging As Method
GB9809780D0 (en) * 1998-05-07 1998-07-08 Nycomed Imaging As Method
DK1360500T3 (da) 2000-04-14 2010-05-25 Genencor Int Fremgangsmåde til selektiv målretning
US7129326B2 (en) 2000-04-14 2006-10-31 Genencor International, Inc. Methods for selective targeting
US20030175685A1 (en) * 2001-02-22 2003-09-18 Praecis Pharmaceuticals Inc. Methods for identifying peptides which modulate a biological process
JP2005514915A (ja) * 2001-09-28 2005-05-26 セレクテックス ファーマシューティカルズ インコーポレーティッド 標的分子と結合する化合物の生成、選択および同定のための方法
CN102584951A (zh) 2002-11-25 2012-07-18 金克克国际有限公司 皮肤或毛发结合肽
EP1599728A1 (de) * 2003-03-04 2005-11-30 Auburn University Verfahren zur herstellung von monoschichten aus phagenprodukten und deren anwendungen
EP1940355B1 (de) 2005-09-30 2012-12-19 Auburn University Nanoträger zur gezielten Freisetzung eines Wirkstoffs - enthaltend Ansammlungen von auf ein Ziel ausgerichteten Landschaftsphagenproteinen
EP2364366B1 (de) 2008-11-05 2014-01-08 MorphoSys AG Dekonvolutionsverfahren
US10161938B2 (en) 2013-12-27 2018-12-25 Roche Sequencing Solutions, Inc. Systematic discovery, maturation and extension of peptide binders to proteins
WO2016074683A1 (en) 2014-11-11 2016-05-19 Lundorf Pedersen Materials Aps Method for identification of molecules with desired characteristics
CA2983351C (en) 2015-04-20 2024-06-04 F. Hoffmann-La Roche Ag Specific peptide binders to proteins identified via systemic discovery, maturation and extension process
EP3907236A1 (de) * 2016-12-22 2021-11-10 Zeon Corporation Oligopeptidsuchverfahren, oligopeptid, modifiziertes peptid und immuntestverfahren

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07119760B2 (ja) * 1984-07-24 1995-12-20 コモンウエルス・セ−ラム・ラボラトリ−ズ・コミッション ミモトープを検出または決定する方法
US5266684A (en) * 1988-05-02 1993-11-30 The Reagents Of The University Of California Peptide mixtures
US5223409A (en) * 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
EP1997891A1 (de) * 1988-09-02 2008-12-03 Dyax Corporation Herstellung und Auswahl von Rekombinantproteinen mit verschiedenen Bindestellen
US5096815A (en) * 1989-01-06 1992-03-17 Protein Engineering Corporation Generation and selection of novel dna-binding proteins and polypeptides
US5198346A (en) * 1989-01-06 1993-03-30 Protein Engineering Corp. Generation and selection of novel DNA-binding proteins and polypeptides
US5366862A (en) * 1990-02-14 1994-11-22 Receptor Laboratories, Inc. Method for generating and screening useful peptides
US5723286A (en) * 1990-06-20 1998-03-03 Affymax Technologies N.V. Peptide library and screening systems
US5650489A (en) * 1990-07-02 1997-07-22 The Arizona Board Of Regents Random bio-oligomer library, a method of synthesis thereof, and a method of use thereof
US6197529B1 (en) * 1990-11-21 2001-03-06 Torrey Pines Institute For Molecular Studies Linear substituted oligoalkyleneimine libraries
US5331573A (en) * 1990-12-14 1994-07-19 Balaji Vitukudi N Method of design of compounds that mimic conformational features of selected peptides
US5475085A (en) * 1991-02-07 1995-12-12 Molecumetics, Ltd. Conformationally restricted mimetics of beta turns and beta bulges and peptides containing the same
US5270170A (en) * 1991-10-16 1993-12-14 Affymax Technologies N.V. Peptide library and screening method
US5470753A (en) * 1992-09-03 1995-11-28 Selectide Corporation Peptide sequencing using mass spectrometry
IL106106A0 (en) * 1993-06-22 1993-10-20 Interpharm Lab Ltd Library of polymeric molecules and its preparation
AU1068295A (en) * 1993-12-09 1995-06-27 Novartis Ag Process for the production of combinatorial compound libraries
US5861476A (en) * 1994-02-02 1999-01-19 Affymax Technologies N.V. Peptides and compounds that bind to the IL-1 receptor
CA2185918A1 (en) * 1994-04-05 1995-10-12 Genzyme Corporation Determination and identification of active compounds in a compound library
US6475806B1 (en) * 1995-06-07 2002-11-05 Praecis Pharmaceuticals, Inc. Anchor libraries and identification of peptide binding sequences

Also Published As

Publication number Publication date
PT868427E (pt) 2003-09-30
US20010006778A1 (en) 2001-07-05
HK1016194A1 (en) 1999-10-29
JP2000502897A (ja) 2000-03-14
AU1430297A (en) 1997-07-14
EP0868427A1 (de) 1998-10-07
EP0868427B1 (de) 2003-05-14
ES2200084T3 (es) 2004-03-01
US20080032896A1 (en) 2008-02-07
DE69628194T2 (de) 2004-04-01
ATE240347T1 (de) 2003-05-15
WO1997022617A1 (en) 1997-06-26
US20030100007A1 (en) 2003-05-29
CA2238995A1 (en) 1997-06-26
US20040091904A1 (en) 2004-05-13
EP1283212A1 (de) 2003-02-12
DK0868427T3 (da) 2003-09-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: PRAECIS PHARMACEUTICALS INC., WALTHAM, MASS., US

8339 Ceased/non-payment of the annual fee