IL135186A0 - LIQUID INTERFERON-β FORMULATIONS - Google Patents

LIQUID INTERFERON-β FORMULATIONS

Info

Publication number
IL135186A0
IL135186A0 IL13518698A IL13518698A IL135186A0 IL 135186 A0 IL135186 A0 IL 135186A0 IL 13518698 A IL13518698 A IL 13518698A IL 13518698 A IL13518698 A IL 13518698A IL 135186 A0 IL135186 A0 IL 135186A0
Authority
IL
Israel
Prior art keywords
buffered
formulations
hsa
contain
free
Prior art date
Application number
IL13518698A
Other languages
English (en)
Original Assignee
Rentschler Biotechnologie Bmgh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8227392&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL135186(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Rentschler Biotechnologie Bmgh filed Critical Rentschler Biotechnologie Bmgh
Publication of IL135186A0 publication Critical patent/IL135186A0/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/21Interferons [IFN]
    • A61K38/215IFN-beta
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/21Interferons [IFN]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Gyroscopes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
IL13518698A 1997-09-23 1998-09-23 LIQUID INTERFERON-β FORMULATIONS IL135186A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP97116562 1997-09-23
PCT/EP1998/006065 WO1999015193A1 (de) 1997-09-23 1998-09-23 FLÜSSIGE INTERFERON-β-FORMULIERUNGEN

Publications (1)

Publication Number Publication Date
IL135186A0 true IL135186A0 (en) 2001-05-20

Family

ID=8227392

Family Applications (3)

Application Number Title Priority Date Filing Date
IL13518698A IL135186A0 (en) 1997-09-23 1998-09-23 LIQUID INTERFERON-β FORMULATIONS
IL135186A IL135186A (en) 1997-09-23 2000-03-20 Liquid formulations of interferon - β that has undergone glycosylation, pharmaceutical preparations containing them, and a process for their preparation and improvement of storage stability
IL211048A IL211048A (en) 1997-09-23 2011-02-03 Liquid formulations of interferon-β

Family Applications After (2)

Application Number Title Priority Date Filing Date
IL135186A IL135186A (en) 1997-09-23 2000-03-20 Liquid formulations of interferon - β that has undergone glycosylation, pharmaceutical preparations containing them, and a process for their preparation and improvement of storage stability
IL211048A IL211048A (en) 1997-09-23 2011-02-03 Liquid formulations of interferon-β

Country Status (13)

Country Link
US (2) US6923956B1 (xx)
EP (3) EP1426058A3 (xx)
JP (1) JP4293497B2 (xx)
KR (2) KR100711990B1 (xx)
AT (2) ATE224726T1 (xx)
AU (1) AU741300B2 (xx)
CA (1) CA2304808C (xx)
DE (2) DE59811910D1 (xx)
DK (1) DK1017413T4 (xx)
ES (2) ES2181281T5 (xx)
IL (3) IL135186A0 (xx)
PT (2) PT1224940E (xx)
WO (1) WO1999015193A1 (xx)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030190307A1 (en) 1996-12-24 2003-10-09 Biogen, Inc. Stable liquid interferon formulations
EP1426058A3 (de) 1997-09-23 2004-07-28 Dr. Rentschler Biotechnologie GmbH Flüssige Interferon-Beta Formulierungen
US6495534B2 (en) * 2000-05-15 2002-12-17 Pharmacia & Upjohn Spa Stabilized aqueous suspensions for parenteral use
US6887462B2 (en) * 2001-04-09 2005-05-03 Chiron Corporation HSA-free formulations of interferon-beta
EP2277910A1 (en) 2001-12-21 2011-01-26 Human Genome Sciences, Inc. Albumin fusion proteins
WO2004007520A2 (en) * 2002-07-12 2004-01-22 Medarex, Inc. Methods and compositions for preventing oxidative degradation of proteins
TWI272948B (en) * 2003-05-01 2007-02-11 Ares Trading Sa HSA-free stabilized interferon liquid formulations
US8277810B2 (en) 2003-11-04 2012-10-02 Novartis Vaccines & Diagnostics, Inc. Antagonist anti-CD40 antibodies
BRPI0418115A (pt) 2003-12-23 2007-04-17 Pharmacia Corp formulação lìquida estável de hormÈnio de crescimento
UA88300C2 (ru) 2004-05-17 2009-10-12 Эйрес Трейдинг С.А. Гидрогелевые композиции, которые содержат интерферон
KR101191536B1 (ko) * 2004-06-01 2012-10-15 아레스 트레이딩 에스.에이. 안정화된 인터페론 액상 제제
EA012281B1 (ru) * 2004-06-01 2009-08-28 Арес Трейдинг С.А. Способ стабилизации белков
US7731948B2 (en) 2004-06-01 2010-06-08 Ares Trading S.A. Stabilized interferon liquid formulations
BRPI0517697A (pt) * 2004-11-10 2008-10-14 Chiron Corp interferon-beta deamidado
MY139088A (en) * 2005-02-21 2009-08-28 Lg Life Sciences Ltd Sustained release composition of protein drug
AU2005335900B2 (en) 2005-08-26 2012-03-29 Ares Trading S.A. Process for the preparation of glycosylated interferon beta
TW200806317A (en) * 2006-03-20 2008-02-01 Wyeth Corp Methods for reducing protein aggregation
DE102007050165B4 (de) * 2007-10-19 2010-06-17 Stiftung Tierärztliche Hochschule Hannover Stabilisierte Lösung, Verfahren zu deren Herstellung sowie deren Verwendung und Arzneimittel in Form einer stabilisierten Lösung
ES2387236T3 (es) 2007-12-20 2012-09-18 Merck Serono S.A. Formulaciones de interferón beta pegilado
US9119866B2 (en) 2008-04-08 2015-09-01 Huiru Wang Glycan-based drugs, therapies and biomarkers
DE102008060960A1 (de) * 2008-12-06 2010-06-10 Boehringer Ingelheim Pharma Gmbh & Co. Kg Optische Füllstandsmessung
DE102009032179A1 (de) 2009-07-07 2011-01-13 Biogenerix Ag Verfahren zur Reinigung von Interferon beta
KR101303388B1 (ko) 2010-10-26 2013-09-03 한미사이언스 주식회사 지속형 인터페론 알파 결합체의 액상 제제
AR083847A1 (es) 2010-11-15 2013-03-27 Novartis Ag Variantes de fc (fragmento constante) silenciosas de los anticuerpos anti-cd40
US8506797B2 (en) * 2011-04-10 2013-08-13 Therapeutic Proteins International, LLC Downstream bioprocessing device
US8852435B2 (en) 2011-11-29 2014-10-07 Therapeutics Proteins International, LLC Purification and separation treatment assembly (PASTA) for biological products
US20140004131A1 (en) 2012-05-04 2014-01-02 Novartis Ag Antibody formulation
PL2919801T3 (pl) * 2012-10-26 2021-01-25 Lupin Atlantis Holdings, Sa Stabilna kompozycja farmaceutyczna białka fuzyjnego TNFR:FC etanerceptu
US9649383B2 (en) * 2012-11-19 2017-05-16 Merck Sharp & Dohme Corp. Liquid formulations for TNFR:Fc fusion proteins
FI126979B (en) 2016-02-29 2017-09-15 Faron Pharmaceuticals Oy Lyophilized pharmaceutical formulation and use thereof

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU538665B2 (en) 1979-10-30 1984-08-23 Juridical Foundation, Japanese Foundation For Cancer Research Human interferon dna
DK170476B1 (da) 1980-04-03 1995-09-11 Biogen Inc Rekombinant DNA-molekyle, uni-cellulær vært transformeret med mindst ét rekombinant DNA-molekyle, fremgangsmåde til transformering af en uni-cellulær vært, samt fremgangsmåder til fremstilling af et polpeptid, der udviser den immunologiske eller biologiske aktivitet af human beta-interferon
DE3273787D1 (en) 1981-02-04 1986-11-20 Japan Found Cancer Human interferon-beta gene
EP0082481B2 (en) 1981-12-23 1990-09-12 Schering Corporation Stabilised alpha-interferon formulations and their preparation
AU1234383A (en) 1982-03-17 1983-09-22 Inter-Yeda Ltd. Interferon stabilised with polyvinyl-pyrrolidone
US4992271A (en) 1982-09-23 1991-02-12 Cetus Corporation Formulation for lipophilic IL-2 proteins
JPS59181224A (ja) 1983-03-29 1984-10-15 Sumitomo Chem Co Ltd 安定なインタ−フエロン製剤の製法
US4816440A (en) 1985-09-26 1989-03-28 Cetus Corporation Stable formulation of biologically active proteins for parenteral injection
CA1294215C (en) 1986-10-27 1992-01-14 Ze'ev Shaked Pharmaceutical compositions of recombinant beta-interferon and formulation processes
US5183746A (en) 1986-10-27 1993-02-02 Schering Aktiengesellschaft Formulation processes for pharmaceutical compositions of recombinant β-
EP0284249A1 (en) 1987-03-13 1988-09-28 Interferon Sciences, Inc. Lyophilized lymphokine composition
DE3712564A1 (de) 1987-04-14 1988-11-24 Bioferon Biochem Substanz Verfahren zur konstruktion einer animalen zellinie fuer die herstellung von humanem interferon-beta
US4895716A (en) 1987-06-09 1990-01-23 Biogen, Inc. Stabilized formulations of gamma interferons
US5151265A (en) * 1987-11-03 1992-09-29 Genentech, Inc. Gamma interferon formulation
US5004605A (en) 1987-12-10 1991-04-02 Cetus Corporation Low pH pharmaceutical compositions of recombinant β-interferon
DE68917883T2 (de) * 1988-05-06 1995-02-23 Toray Industries Stabile interferon-beta-zusammensetzung.
US5272135A (en) 1991-03-01 1993-12-21 Chiron Ophthalmics, Inc. Method for the stabilization of methionine-containing polypeptides
DE4128319A1 (de) * 1991-08-27 1993-03-04 Bioferon Biochem Substanz Neues rekombinantes human-ifn-beta, verfahren zu dessen herstellung und dieses enthaltende pharmazeutische zubereitungen
US5358708A (en) * 1993-01-29 1994-10-25 Schering Corporation Stabilization of protein formulations
JPH06247870A (ja) 1993-02-23 1994-09-06 Ajinomoto Co Inc インターロイキン−6を含有する医薬製剤
IT1272252B (it) 1994-05-16 1997-06-16 Applied Research Systems Formulazioni liquide di interferone beta
CA2275890C (en) 1996-12-24 2011-11-01 Biogen, Inc. Stable liquid interferon formulations
EP1426058A3 (de) 1997-09-23 2004-07-28 Dr. Rentschler Biotechnologie GmbH Flüssige Interferon-Beta Formulierungen

Also Published As

Publication number Publication date
CA2304808A1 (en) 1999-04-01
EP1017413B2 (de) 2007-11-07
IL211048A (en) 2012-12-31
CA2304808C (en) 2011-03-22
IL135186A (en) 2012-12-31
PT1017413E (pt) 2003-02-28
DE59811910D1 (de) 2004-10-07
EP1017413B1 (de) 2002-09-25
ES2181281T3 (es) 2003-02-16
EP1426058A2 (de) 2004-06-09
ES2181281T5 (es) 2008-04-16
EP1224940A1 (de) 2002-07-24
WO1999015193A1 (de) 1999-04-01
US20050186177A1 (en) 2005-08-25
ES2223017T3 (es) 2005-02-16
US6923956B1 (en) 2005-08-02
EP1224940A8 (de) 2002-11-20
EP1426058A3 (de) 2004-07-28
KR20060088910A (ko) 2006-08-07
AU9627698A (en) 1999-04-12
US8337826B2 (en) 2012-12-25
ATE224726T1 (de) 2002-10-15
KR100826621B1 (ko) 2008-05-02
PT1224940E (pt) 2005-01-31
DK1017413T3 (da) 2003-02-03
ES2223017T5 (es) 2010-10-15
KR100711990B1 (ko) 2007-05-02
JP2001517635A (ja) 2001-10-09
EP1224940B2 (de) 2010-08-11
ATE274917T1 (de) 2004-09-15
DK1017413T4 (da) 2008-03-25
AU741300B2 (en) 2001-11-29
EP1017413A1 (de) 2000-07-12
KR20010015599A (ko) 2001-02-26
EP1224940B1 (de) 2004-09-01
DE59805732D1 (de) 2002-10-31
JP4293497B2 (ja) 2009-07-08

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