IL134648A0 - Tie ligand homologues - Google Patents
Tie ligand homologuesInfo
- Publication number
- IL134648A0 IL134648A0 IL13464898A IL13464898A IL134648A0 IL 134648 A0 IL134648 A0 IL 134648A0 IL 13464898 A IL13464898 A IL 13464898A IL 13464898 A IL13464898 A IL 13464898A IL 134648 A0 IL134648 A0 IL 134648A0
- Authority
- IL
- Israel
- Prior art keywords
- tie ligand
- nucleic acid
- ligand homologues
- acid molecules
- protein
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/515—Angiogenesic factors; Angiogenin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/70—Nanostructure
- Y10S977/773—Nanoparticle, i.e. structure having three dimensions of 100 nm or less
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/70—Nanostructure
- Y10S977/788—Of specified organic or carbon-based composition
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/915—Therapeutic or pharmaceutical composition
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Toxicology (AREA)
- Biotechnology (AREA)
- Vascular Medicine (AREA)
- Wood Science & Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- General Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Plant Pathology (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Microbiology (AREA)
- Dermatology (AREA)
- Physics & Mathematics (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/933,821 US5972338A (en) | 1997-09-19 | 1997-09-19 | Tie ligands homologues |
US08/960,507 US6057435A (en) | 1997-09-19 | 1997-10-29 | Tie ligand homologues |
PCT/US1998/019093 WO1999015653A2 (en) | 1997-09-19 | 1998-09-14 | Tie ligand homologues |
Publications (1)
Publication Number | Publication Date |
---|---|
IL134648A0 true IL134648A0 (en) | 2001-04-30 |
Family
ID=27130048
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL13464898A IL134648A0 (en) | 1997-09-19 | 1998-09-14 | Tie ligand homologues |
IL134648A IL134648A (en) | 1997-09-19 | 2000-02-21 | Homologues of TIE legends |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL134648A IL134648A (en) | 1997-09-19 | 2000-02-21 | Homologues of TIE legends |
Country Status (15)
Country | Link |
---|---|
US (3) | US6057435A (pt) |
EP (4) | EP1015585B1 (pt) |
JP (4) | JP2001517437A (pt) |
KR (4) | KR100692333B1 (pt) |
AT (1) | ATE327329T1 (pt) |
AU (1) | AU756449B2 (pt) |
CA (1) | CA2304129A1 (pt) |
CY (1) | CY1105161T1 (pt) |
DE (1) | DE69834649T2 (pt) |
DK (1) | DK1015585T3 (pt) |
ES (1) | ES2268790T3 (pt) |
IL (2) | IL134648A0 (pt) |
NZ (1) | NZ502946A (pt) |
PT (1) | PT1015585E (pt) |
WO (1) | WO1999015653A2 (pt) |
Families Citing this family (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001034800A1 (en) * | 1999-11-12 | 2001-05-17 | Human Genome Sciences, Inc. | 19 human secreted proteins |
US6350450B1 (en) * | 1997-09-19 | 2002-02-26 | Genentech, Inc. | TIE ligand homologue antibody |
US6057435A (en) | 1997-09-19 | 2000-05-02 | Genentech, Inc. | Tie ligand homologues |
US5972338A (en) * | 1997-09-19 | 1999-10-26 | Genentech, Inc. | Tie ligands homologues |
CA2313804A1 (en) * | 1997-12-19 | 1999-07-01 | Regeneron Pharmaceuticals, Inc. | Receptor tyrosine kinase, ar-1, is a regulator of angiogenesis |
AU2493699A (en) * | 1998-02-04 | 1999-08-23 | Zymogenetics Inc. | Angiopoietin homolog zapo3, dna encoding it, and method of making it |
WO1999055869A1 (en) * | 1998-04-27 | 1999-11-04 | Zymogenetics, Inc. | Novel polypeptide growth factors and materials and methods for making them |
AU4320499A (en) * | 1998-06-02 | 1999-12-20 | Eli Lilly And Company | Angiopoietin related gene sequence scarface 1 |
SV1999000069A (es) * | 1998-06-02 | 2000-04-11 | Lilly Co Eli | Angiopoyetina relacionada con secuencia del gen 3 en la cicatrizacion de la cara ref. x-12261 |
AU4643699A (en) * | 1998-06-24 | 2000-01-10 | Compugen Ltd. | Angiopoietin-like growth factor sequences |
CA2331789C (en) * | 1998-07-13 | 2013-09-10 | Board Of Regents, The University Of Texas System | Cancer treatment methods using therapeutic conjugates that bind to aminophospholipids |
US6818213B1 (en) * | 1998-07-13 | 2004-11-16 | Board Of Regents, The University Of Texas System | Cancer treatment compositions comprising therapeutic conjugates that bind to aminophospholipids |
US6406693B1 (en) | 1998-07-13 | 2002-06-18 | Board Of Regents, The University Of Texas System | Cancer treatment methods using antibodies to aminophospholipids |
WO2000002584A2 (en) | 1998-07-13 | 2000-01-20 | Board Of Regents, The University Of Texas System | Cancer treatment methods using antibodies to aminophospholipids |
AU5081899A (en) * | 1998-07-20 | 2000-02-14 | Curagen Corporation | Nucleotide sequences and amino acid sequences of secreted proteins involved in angiogenesis |
AU5210899A (en) * | 1998-07-24 | 2000-02-14 | Eli Lilly And Company | Angiopoietin related gene sequence scarface 2 |
AU5472899A (en) * | 1998-08-20 | 2000-03-14 | Incyte Pharmaceuticals, Inc. | Human angiopoietin-3 |
US6537554B1 (en) | 1998-09-10 | 2003-03-25 | Curagen Corporation | Nucleotide sequences and amino acid sequences of secreted proteins involved in angiogenesis |
US20050148101A1 (en) * | 1999-01-23 | 2005-07-07 | Bamdad Cynthia C. | Interaction of colloid-immobilized species with species on non-colloidal structures |
EP1157111A1 (en) * | 1999-03-02 | 2001-11-28 | Regeneron Pharmaceuticals, Inc. | Angiopoietin-related protein and nucleic acids |
KR20010104373A (ko) * | 1999-03-08 | 2001-11-24 | 제넨테크, 인크. | 혈관신생 및 심혈관형성의 촉진 또는 억제 방법 |
US6703020B1 (en) | 1999-04-28 | 2004-03-09 | Board Of Regents, The University Of Texas System | Antibody conjugate methods for selectively inhibiting VEGF |
US6887468B1 (en) | 1999-04-28 | 2005-05-03 | Board Of Regents, The University Of Texas System | Antibody kits for selectively inhibiting VEGF |
ATE449109T1 (de) * | 1999-06-15 | 2009-12-15 | Genentech Inc | Sekretierte und transmembran-polypeptide sowie nukleinsäuren zu deren kodierung |
CA2377788A1 (en) * | 1999-07-02 | 2001-01-11 | Bayer Ag | Methods for modulating angiogenesis by using the anti-angiogenic angiotensin-7 and polynucleotides encoding therefor |
US6835381B1 (en) | 1999-07-02 | 2004-12-28 | Bayer Ag | Methods for modulating angiogenesis by using the anti-angiogenic angiotensin-7 and polynucleotides encoding therefor |
WO2001003735A1 (en) * | 1999-07-12 | 2001-01-18 | Maine Medical Center Research Institute | Cancer treatment using angiopoietins targeted to aminophospholipids |
DE60035693T2 (de) * | 1999-07-20 | 2008-05-15 | Genentech, Inc., South San Francisco | Zusammensetzung und verfahren zur behandlung von immunverwandten krankheiten |
WO2001029085A2 (en) * | 1999-10-21 | 2001-04-26 | Royal Netherlands Academy Of Arts And Sciences | Cdt6 can inhibit angiogenesis and tumor growth, and can induce or enhance the formation of structures containing collagen v |
EP1381440B1 (en) * | 2000-10-03 | 2013-01-30 | Minerva Biotechnologies Corporation | Miniaturized pressure drop filter and methods of using it |
WO2003062373A2 (en) * | 2001-10-18 | 2003-07-31 | The Children's Hospital Of Philadelphia | Methods and materials for the recruitment of endothelial cells |
US20050123925A1 (en) * | 2002-11-15 | 2005-06-09 | Genentech, Inc. | Compositions and methods for the diagnosis and treatment of tumor |
JPWO2003083114A1 (ja) * | 2002-03-28 | 2005-08-04 | アステラス製薬株式会社 | アンジオポエチン関連増殖因子 |
EP1593740A4 (en) * | 2003-06-06 | 2006-12-06 | Astellas Pharma Inc | PROCEDURE FOR SCREENING MEDICINE AGAINST OBESITY AND OBESITY ANIMAL MODEL |
US7871610B2 (en) * | 2003-08-12 | 2011-01-18 | Dyax Corp. | Antibodies to Tie1 ectodomain |
EP1656392A2 (en) * | 2003-08-12 | 2006-05-17 | Dyax Corp. | Tie1-binding ligands |
US7485297B2 (en) * | 2003-08-12 | 2009-02-03 | Dyax Corp. | Method of inhibition of vascular development using an antibody |
ZA200702321B (en) * | 2004-08-25 | 2009-09-30 | Genentech Inc | Novel gene disruptions, compositions and methods relating thereto |
CA2589538A1 (en) * | 2004-12-03 | 2006-06-08 | Astellas Pharma Inc. | Method of screening antiobesity agents |
WO2006066071A2 (en) * | 2004-12-17 | 2006-06-22 | Mayo Foundation For Medical Education And Research | Prognosis of renal cell carcinoma |
WO2008089070A2 (en) * | 2007-01-12 | 2008-07-24 | Dyax Corp. | Combination therapy for the treatment of cancer |
US20090104210A1 (en) * | 2007-10-17 | 2009-04-23 | Tota Michael R | Peptide compounds for treating obesity and insulin resistance |
AU2009262199B2 (en) | 2008-06-27 | 2012-08-09 | Amgen Inc. | Ang-2 inhibition to treat multiple sclerosis |
EP2494362B1 (en) | 2009-10-26 | 2016-06-08 | Externautics S.p.A. | Prostate tumor markers and methods of use thereof |
EP2494361B2 (en) | 2009-10-26 | 2019-01-09 | Externautics S.p.A. | Ovary tumor markers and methods of use thereof |
EP2494351B1 (en) * | 2009-10-26 | 2016-06-08 | Externautics S.p.A. | Colon and rectal tumor markers and methods of use thereof |
KR101109486B1 (ko) * | 2009-10-29 | 2012-01-31 | 현대제철 주식회사 | 크레인 그래브용 체결장치 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5955291A (en) * | 1992-01-09 | 1999-09-21 | Alitalo; Kari | Antibodies recognizing tie receptor tyrosine kinase and uses thereof |
JPH07506242A (ja) * | 1992-01-09 | 1995-07-13 | ヘルシンキ ユニバーシティ ホルディング リミテッド | Tie,新規内皮細胞受容体チロシンキナーゼ |
AU4651893A (en) * | 1992-06-26 | 1994-01-24 | Immunex Corporation | Novel tyrosine kinase |
AU8143094A (en) * | 1993-11-12 | 1995-05-29 | Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. | (tie-2), a novel receptor tyrosine kinase |
US5643755A (en) * | 1994-10-07 | 1997-07-01 | Regeneron Pharmaceuticals Inc. | Nucleic acid encoding tie-2 ligand |
AUPM379494A0 (en) * | 1994-02-10 | 1994-03-03 | Ludwig Institute For Cancer Research | Immunointeractive molecules - ii |
WO1996009381A1 (en) * | 1994-09-22 | 1996-03-28 | Helsinki University Licensing Ltd. Oy | Promoter for the receptor tyrosine kinase, tie |
US5814464A (en) | 1994-10-07 | 1998-09-29 | Regeneron Pharma | Nucleic acids encoding TIE-2 ligand-2 |
US5650490A (en) * | 1994-10-07 | 1997-07-22 | Regeneron Pharmaceuticals, Inc. | Tie-2 ligand 2 |
AU3826295A (en) * | 1994-10-13 | 1996-05-06 | Boeing Company, The | Jet engine fan noise reduction system utilizing electro pneumatic transducers |
AU715621B2 (en) * | 1995-04-06 | 2000-02-03 | Regeneron Pharmaceuticals, Inc. | TIE-2 ligands, methods of making and uses thereof |
US5851797A (en) * | 1996-06-19 | 1998-12-22 | Regeneron Pharmaceuticals, Inc. | Tie ligand-3, methods of making and uses thereof |
DK0939809T3 (da) * | 1996-06-19 | 2003-07-21 | Regeneron Pharma | TIE-2 receptor-ligand (TIE ligand-4) og dens anvendelse |
US5972338A (en) | 1997-09-19 | 1999-10-26 | Genentech, Inc. | Tie ligands homologues |
US6057435A (en) | 1997-09-19 | 2000-05-02 | Genentech, Inc. | Tie ligand homologues |
US6030831A (en) * | 1997-09-19 | 2000-02-29 | Genetech, Inc. | Tie ligand homologues |
-
1997
- 1997-10-29 US US08/960,507 patent/US6057435A/en not_active Expired - Fee Related
-
1998
- 1998-08-19 US US09/136,801 patent/US6413770B1/en not_active Expired - Fee Related
- 1998-09-14 JP JP2000512945A patent/JP2001517437A/ja not_active Ceased
- 1998-09-14 US US09/202,088 patent/US6551822B1/en not_active Expired - Fee Related
- 1998-09-14 NZ NZ502946A patent/NZ502946A/en not_active IP Right Cessation
- 1998-09-14 KR KR1020067007637A patent/KR100692333B1/ko not_active IP Right Cessation
- 1998-09-14 EP EP98946987A patent/EP1015585B1/en not_active Expired - Lifetime
- 1998-09-14 PT PT98946987T patent/PT1015585E/pt unknown
- 1998-09-14 KR KR1020067007636A patent/KR100692336B1/ko not_active IP Right Cessation
- 1998-09-14 ES ES98946987T patent/ES2268790T3/es not_active Expired - Lifetime
- 1998-09-14 CA CA002304129A patent/CA2304129A1/en not_active Abandoned
- 1998-09-14 DE DE69834649T patent/DE69834649T2/de not_active Expired - Lifetime
- 1998-09-14 WO PCT/US1998/019093 patent/WO1999015653A2/en active IP Right Grant
- 1998-09-14 EP EP06007999A patent/EP1724349A1/en not_active Withdrawn
- 1998-09-14 EP EP06007995A patent/EP1696029A1/en not_active Withdrawn
- 1998-09-14 DK DK98946987T patent/DK1015585T3/da active
- 1998-09-14 IL IL13464898A patent/IL134648A0/xx active IP Right Grant
- 1998-09-14 KR KR1020007002910A patent/KR100692335B1/ko not_active IP Right Cessation
- 1998-09-14 AU AU93880/98A patent/AU756449B2/en not_active Ceased
- 1998-09-14 EP EP06007996A patent/EP1696030A1/en not_active Withdrawn
- 1998-09-14 KR KR1020067007638A patent/KR100692334B1/ko not_active IP Right Cessation
- 1998-09-14 AT AT98946987T patent/ATE327329T1/de active
-
2000
- 2000-02-21 IL IL134648A patent/IL134648A/en not_active IP Right Cessation
-
2003
- 2003-09-10 JP JP2003318260A patent/JP2004113239A/ja active Pending
- 2003-09-10 JP JP2003318338A patent/JP2004129656A/ja active Pending
- 2003-09-10 JP JP2003318295A patent/JP2004097224A/ja active Pending
-
2006
- 2006-08-22 CY CY20061101164T patent/CY1105161T1/el unknown
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB | Patent renewed | ||
KB | Patent renewed |