IL132126A0 - Aqueous immunologic adjuvant compositions of monophosphoryl lipid a - Google Patents
Aqueous immunologic adjuvant compositions of monophosphoryl lipid aInfo
- Publication number
- IL132126A0 IL132126A0 IL13212698A IL13212698A IL132126A0 IL 132126 A0 IL132126 A0 IL 132126A0 IL 13212698 A IL13212698 A IL 13212698A IL 13212698 A IL13212698 A IL 13212698A IL 132126 A0 IL132126 A0 IL 132126A0
- Authority
- IL
- Israel
- Prior art keywords
- surfactant
- lipid
- derivative
- attenuated
- monophosphoryl lipid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
- C07H13/06—Fatty acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Mycology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Pulmonology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US83107397A | 1997-04-01 | 1997-04-01 | |
PCT/US1998/006528 WO1998043670A2 (en) | 1997-04-01 | 1998-04-01 | Aqueous immunologic adjuvant compositions of monophosphoryl lipid a |
Publications (1)
Publication Number | Publication Date |
---|---|
IL132126A0 true IL132126A0 (en) | 2001-03-19 |
Family
ID=25258229
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL13212698A IL132126A0 (en) | 1997-04-01 | 1998-04-01 | Aqueous immunologic adjuvant compositions of monophosphoryl lipid a |
IL132126A IL132126A (en) | 1997-04-01 | 1999-09-29 | Aqueous compositions of monophosphoryl lipid A as an immunological supplement |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL132126A IL132126A (en) | 1997-04-01 | 1999-09-29 | Aqueous compositions of monophosphoryl lipid A as an immunological supplement |
Country Status (19)
Country | Link |
---|---|
EP (1) | EP0971739B1 (pt) |
JP (1) | JP5019494B2 (pt) |
KR (1) | KR100603884B1 (pt) |
CN (2) | CN1259052A (pt) |
AT (1) | ATE278419T1 (pt) |
AU (1) | AU743114B2 (pt) |
BR (1) | BR9811262A (pt) |
CA (1) | CA2284586C (pt) |
DE (1) | DE69826842T2 (pt) |
ES (1) | ES2227825T3 (pt) |
HK (1) | HK1026613A1 (pt) |
HU (1) | HUP0001403A3 (pt) |
IL (2) | IL132126A0 (pt) |
NO (1) | NO994760L (pt) |
NZ (1) | NZ338101A (pt) |
PL (1) | PL190237B1 (pt) |
PT (1) | PT971739E (pt) |
TR (1) | TR199902437T2 (pt) |
WO (1) | WO1998043670A2 (pt) |
Families Citing this family (71)
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US6491919B2 (en) * | 1997-04-01 | 2002-12-10 | Corixa Corporation | Aqueous immunologic adjuvant compostions of monophosphoryl lipid A |
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GB9820525D0 (en) | 1998-09-21 | 1998-11-11 | Allergy Therapeutics Ltd | Formulation |
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US20030031684A1 (en) | 2001-03-30 | 2003-02-13 | Corixa Corporation | Methods for the production of 3-O-deactivated-4'-monophosphoryl lipid a (3D-MLA) |
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US20100221284A1 (en) | 2001-05-30 | 2010-09-02 | Saech-Sisches Serumwerk Dresden | Novel vaccine composition |
MY134424A (en) | 2001-05-30 | 2007-12-31 | Saechsisches Serumwerk | Stable influenza virus preparations with low or no amount of thiomersal |
GB0321615D0 (en) | 2003-09-15 | 2003-10-15 | Glaxo Group Ltd | Improvements in vaccination |
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GB0503337D0 (en) | 2005-02-17 | 2005-03-23 | Glaxosmithkline Biolog Sa | Compositions |
GB0504436D0 (en) | 2005-03-03 | 2005-04-06 | Glaxosmithkline Biolog Sa | Vaccine |
CN106390108B (zh) | 2005-04-29 | 2020-09-08 | 葛兰素史密丝克莱恩生物有限公司 | 用于预防或治疗结核分枝杆菌感染的新方法 |
EA014314B1 (ru) * | 2005-08-02 | 2010-10-29 | Новартис Вэксинес Энд Дайэгностикс Срл | Пониженная интерференция между маслосодержащими адъювантами и антигенами, содержащими поверхностно-активные вещества |
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US8018440B2 (en) | 2005-12-30 | 2011-09-13 | Microsoft Corporation | Unintentional touch rejection |
US20090181078A1 (en) | 2006-09-26 | 2009-07-16 | Infectious Disease Research Institute | Vaccine composition containing synthetic adjuvant |
CN101516396B (zh) | 2006-09-26 | 2013-10-09 | 传染性疾病研究院 | 包含合成佐剂的疫苗组合物 |
US8836648B2 (en) | 2009-05-27 | 2014-09-16 | Microsoft Corporation | Touch pull-in gesture |
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US8261213B2 (en) | 2010-01-28 | 2012-09-04 | Microsoft Corporation | Brush, carbon-copy, and fill gestures |
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US9104440B2 (en) | 2011-05-27 | 2015-08-11 | Microsoft Technology Licensing, Llc | Multi-application environment |
US9104307B2 (en) | 2011-05-27 | 2015-08-11 | Microsoft Technology Licensing, Llc | Multi-application environment |
US9158445B2 (en) | 2011-05-27 | 2015-10-13 | Microsoft Technology Licensing, Llc | Managing an immersive interface in a multi-application immersive environment |
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US9146670B2 (en) | 2011-09-10 | 2015-09-29 | Microsoft Technology Licensing, Llc | Progressively indicating new content in an application-selectable user interface |
EP2755684A1 (en) | 2011-09-12 | 2014-07-23 | Jonathan Norden Weber | Methods and compositions for raising an immune response to hiv |
BR112014028476A2 (pt) | 2012-05-16 | 2017-08-01 | Immune Design Corp | fragmento imunogênico de um polipeptídeo, polinucleotídeo isolado, composição farmacêutica imunogênica, métodos para tratar uma infecção, para gerar uma resposta imune em um sujeito, e para imunizar um sujeito |
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WO2022251444A1 (en) * | 2021-05-27 | 2022-12-01 | Revelation Biosciences, Inc. | Mpla compositions and methods of use |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4912094B1 (en) * | 1988-06-29 | 1994-02-15 | Ribi Immunochem Research Inc. | Modified lipopolysaccharides and process of preparation |
US5068191A (en) * | 1989-08-31 | 1991-11-26 | The Biomembrane Institute | Purified histo-blood group a glycosyltransferase and antibodies thereto |
US5552141A (en) * | 1991-10-30 | 1996-09-03 | Ribi; Hans O. | Polymeric immunological adjuvants |
ES2109685T5 (es) * | 1993-03-23 | 2005-09-01 | Smithkline Beecham Biologicals S.A. | Composiciones para vacunas que contienen monofosforil-lipido a 3-o-desacilado. |
-
1998
- 1998-04-01 KR KR1019997008958A patent/KR100603884B1/ko not_active IP Right Cessation
- 1998-04-01 PT PT98915239T patent/PT971739E/pt unknown
- 1998-04-01 BR BR9811262-7A patent/BR9811262A/pt not_active Application Discontinuation
- 1998-04-01 IL IL13212698A patent/IL132126A0/xx active IP Right Grant
- 1998-04-01 CN CN98804685A patent/CN1259052A/zh active Pending
- 1998-04-01 PL PL98336698A patent/PL190237B1/pl not_active IP Right Cessation
- 1998-04-01 ES ES98915239T patent/ES2227825T3/es not_active Expired - Lifetime
- 1998-04-01 EP EP98915239A patent/EP0971739B1/en not_active Expired - Lifetime
- 1998-04-01 AT AT98915239T patent/ATE278419T1/de active
- 1998-04-01 NZ NZ338101A patent/NZ338101A/en unknown
- 1998-04-01 AU AU69473/98A patent/AU743114B2/en not_active Ceased
- 1998-04-01 TR TR1999/02437T patent/TR199902437T2/xx unknown
- 1998-04-01 HU HU0001403A patent/HUP0001403A3/hu unknown
- 1998-04-01 DE DE69826842T patent/DE69826842T2/de not_active Expired - Lifetime
- 1998-04-01 CN CNB2004100713486A patent/CN1326564C/zh not_active Expired - Fee Related
- 1998-04-01 CA CA2284586A patent/CA2284586C/en not_active Expired - Lifetime
- 1998-04-01 JP JP54200198A patent/JP5019494B2/ja not_active Expired - Lifetime
- 1998-04-01 WO PCT/US1998/006528 patent/WO1998043670A2/en active IP Right Grant
-
1999
- 1999-09-29 IL IL132126A patent/IL132126A/en not_active IP Right Cessation
- 1999-09-30 NO NO994760A patent/NO994760L/no not_active Application Discontinuation
-
2000
- 2000-07-19 HK HK00104464A patent/HK1026613A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
JP2001526640A (ja) | 2001-12-18 |
DE69826842D1 (de) | 2004-11-11 |
ES2227825T3 (es) | 2005-04-01 |
NO994760D0 (no) | 1999-09-30 |
WO1998043670A2 (en) | 1998-10-08 |
NZ338101A (en) | 2002-03-28 |
JP5019494B2 (ja) | 2012-09-05 |
PT971739E (pt) | 2004-12-31 |
ATE278419T1 (de) | 2004-10-15 |
IL132126A (en) | 2006-10-05 |
NO994760L (no) | 1999-11-26 |
PL190237B1 (pl) | 2005-11-30 |
WO1998043670A3 (en) | 1998-12-30 |
KR100603884B1 (ko) | 2006-07-24 |
HUP0001403A3 (en) | 2003-05-28 |
DE69826842T2 (de) | 2005-11-24 |
HK1026613A1 (en) | 2000-12-22 |
HUP0001403A2 (hu) | 2000-09-28 |
CN1575815A (zh) | 2005-02-09 |
BR9811262A (pt) | 2000-10-17 |
CA2284586C (en) | 2011-02-08 |
AU6947398A (en) | 1998-10-22 |
PL336698A1 (en) | 2000-07-03 |
TR199902437T2 (xx) | 2000-01-21 |
CN1326564C (zh) | 2007-07-18 |
AU743114B2 (en) | 2002-01-17 |
EP0971739A2 (en) | 2000-01-19 |
KR20010005882A (ko) | 2001-01-15 |
CN1259052A (zh) | 2000-07-05 |
CA2284586A1 (en) | 1998-10-08 |
EP0971739B1 (en) | 2004-10-06 |
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Legal Events
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FF | Patent granted | ||
KB | Patent renewed | ||
KB | Patent renewed |