IL131751A0 - Aryl-or heteroarylsulfonamide substituted hydroxamic acid derivatives process for their preparation and their use as pharmaceuticals - Google Patents
Aryl-or heteroarylsulfonamide substituted hydroxamic acid derivatives process for their preparation and their use as pharmaceuticalsInfo
- Publication number
- IL131751A0 IL131751A0 IL13175198A IL13175198A IL131751A0 IL 131751 A0 IL131751 A0 IL 131751A0 IL 13175198 A IL13175198 A IL 13175198A IL 13175198 A IL13175198 A IL 13175198A IL 131751 A0 IL131751 A0 IL 131751A0
- Authority
- IL
- Israel
- Prior art keywords
- heteroarylsulfonamide
- pharmaceuticals
- aryl
- preparation
- acid derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
- C07C311/19—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
- C07C311/29—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9706255.8A GB9706255D0 (en) | 1997-03-26 | 1997-03-26 | Novel compounds |
| PCT/EP1998/001766 WO1998042659A2 (en) | 1997-03-26 | 1998-03-16 | Aryl- or heteroarylsulfonamide substituted hydroxamic acid derivates, process for their preparation and their use as pharmaceuticals |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL131751A0 true IL131751A0 (en) | 2001-03-19 |
Family
ID=10809882
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL13175198A IL131751A0 (en) | 1997-03-26 | 1998-03-16 | Aryl-or heteroarylsulfonamide substituted hydroxamic acid derivatives process for their preparation and their use as pharmaceuticals |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US6242467B1 (hu) |
| EP (1) | EP0973732A2 (hu) |
| JP (1) | JP2001518922A (hu) |
| KR (1) | KR20010005627A (hu) |
| CN (1) | CN1251091A (hu) |
| AR (1) | AR012294A1 (hu) |
| AU (1) | AU7210598A (hu) |
| BR (1) | BR9808366A (hu) |
| CA (1) | CA2285439A1 (hu) |
| CO (1) | CO4950563A1 (hu) |
| GB (1) | GB9706255D0 (hu) |
| HU (1) | HUP0003021A3 (hu) |
| IL (1) | IL131751A0 (hu) |
| NO (1) | NO994671D0 (hu) |
| PL (1) | PL336039A1 (hu) |
| TR (1) | TR199902357T2 (hu) |
| WO (1) | WO1998042659A2 (hu) |
| ZA (1) | ZA982517B (hu) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5904697A (en) * | 1995-02-24 | 1999-05-18 | Heartport, Inc. | Devices and methods for performing a vascular anastomosis |
| HUP0004595A3 (en) | 1997-07-31 | 2001-12-28 | Procter & Gamble | Acyclic metalloprotease inhibitors |
| US6403632B1 (en) * | 2000-03-01 | 2002-06-11 | Bristol Myers Squibb Pharma Co | Lactam metalloprotease inhibitors |
| US6753337B2 (en) | 1999-01-27 | 2004-06-22 | Wyeth Holdings Corporation | Alkynyl containing hydroxamic acid compounds as matrix metalloproteinase/tace inhibitors |
| US6946473B2 (en) | 1999-01-27 | 2005-09-20 | Wyeth Holdings Corporation | Preparation and use of acetylenic ortho-sulfonamido and phosphinic acid amido bicyclic heteroaryl hydroxamic acids as TACE inhibitors |
| EP1147085B1 (en) | 1999-01-27 | 2005-11-16 | Wyeth Holdings Corporation | Alkynyl containing hydroxamic acid derivatives, their preparation and their use as matrix metalloproteinase (mmp) inhibitors / tnf-alpha converting enzyme (tace) inhibitors |
| US6340691B1 (en) | 1999-01-27 | 2002-01-22 | American Cyanamid Company | Alkynyl containing hydroxamic acid compounds as matrix metalloproteinase and tace inhibitors |
| US6313123B1 (en) | 1999-01-27 | 2001-11-06 | American Cyanamid Company | Acetylenic sulfonamide thiol tace inhibitors |
| US6326516B1 (en) | 1999-01-27 | 2001-12-04 | American Cyanamid Company | Acetylenic β-sulfonamido and phosphinic acid amide hydroxamic acid TACE inhibitors |
| US6762178B2 (en) | 1999-01-27 | 2004-07-13 | Wyeth Holdings Corporation | Acetylenic aryl sulfonamide and phosphinic acid amide hydroxamic acid TACE inhibitors |
| US6277885B1 (en) | 1999-01-27 | 2001-08-21 | American Cyanamid Company | Acetylenic aryl sulfonamide and phosphinic acid amide hydroxamic acid TACE inhibitors |
| US6225311B1 (en) | 1999-01-27 | 2001-05-01 | American Cyanamid Company | Acetylenic α-amino acid-based sulfonamide hydroxamic acid tace inhibitors |
| US6200996B1 (en) | 1999-01-27 | 2001-03-13 | American Cyanamid Company | Heteroaryl acetylenic sulfonamide and phosphinic acid amide hydroxamic acid tace inhibitors |
| JP2002538136A (ja) | 1999-03-03 | 2002-11-12 | ザ プロクター アンド ギャンブル カンパニー | アルケニルおよびアルキニル含有メタロプロテアーゼ阻害剤 |
| HUP0201714A3 (en) | 1999-03-03 | 2003-05-28 | Procter & Gamble | Substituted heterocyclic compounds and pharmaceutical compositions containing them |
| GB9922825D0 (en) * | 1999-09-25 | 1999-11-24 | Smithkline Beecham Biolog | Medical use |
| US6808902B1 (en) | 1999-11-12 | 2004-10-26 | Amgen Inc. | Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules |
| WO2001062715A1 (en) * | 2000-02-24 | 2001-08-30 | Smithkline Beecham P.L.C. | Novel cd23 inhibitors |
| CN1440400A (zh) * | 2000-05-25 | 2003-09-03 | 史密斯克莱·比奇曼公司 | 二环基或杂二环基甲磺酰氨基－取代的n－羟基甲酰胺化合物 |
| JP4212470B2 (ja) | 2001-06-26 | 2009-01-21 | アムジェン フレモント インク． | Ｏｐｇｌへの抗体 |
| EP1440057A1 (en) | 2001-11-01 | 2004-07-28 | Wyeth Holdings Corporation | Allenic aryl sulfonamide hydroxamic acids as matrix metalloproteinase and tace inhibitors |
| GB0128376D0 (en) * | 2001-11-27 | 2002-01-16 | Smithkline Beecham Plc | Novel compounds |
| DE60233688D1 (de) * | 2001-12-27 | 2009-10-22 | Lg Electronics Inc | Waschmaschine |
| ATE429909T1 (de) * | 2002-05-29 | 2009-05-15 | Merck & Co Inc | Nützliche verbindungen für die behandlung von anthrax und hemmung des letalen faktors |
| US7199155B2 (en) | 2002-12-23 | 2007-04-03 | Wyeth Holdings Corporation | Acetylenic aryl sulfonate hydroxamic acid TACE and matrix metalloproteinase inhibitors |
| EP1747212A4 (en) | 2004-05-11 | 2009-03-25 | Merck & Co Inc | PROCESS FOR PRODUCING N-SULFINATED AMINO ACID DERIVATIVES |
| US20110112076A1 (en) * | 2008-07-14 | 2011-05-12 | Mcquire Leslie Wighton | Selective hydroxamic acid based mmp-12 and mmp-13 inhibitors |
| USD810196S1 (en) * | 2015-04-14 | 2018-02-13 | Marcia D. Fackler | Sunglass book cover |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5455258A (en) | 1993-01-06 | 1995-10-03 | Ciba-Geigy Corporation | Arylsulfonamido-substituted hydroxamic acids |
| CA2193691A1 (en) * | 1994-06-22 | 1995-12-28 | Andrew Miller | Metalloproteinase inhibitors |
| GB9414157D0 (en) * | 1994-07-13 | 1994-08-31 | Smithkline Beecham Plc | Medical use |
| MX9801093A (es) | 1995-08-08 | 1998-04-30 | Fibrogen Inc | Inhibidores de la proteinasa c para el tratamiento de enfermedades relacionadas con la sobreproduccion de colagena. |
| DK0757984T3 (da) | 1995-08-08 | 2003-03-03 | Ono Pharmaceutical Co | Hydroxamsyrederivater, der kan anvendes til inhibering af gelatinase |
| DK0901466T3 (da) | 1996-05-17 | 2002-02-18 | Warner Lambert Co | Biphenylsulfonamid-matriksmetalloproteinase-inhibitorer |
| JP2000517341A (ja) | 1996-09-04 | 2000-12-26 | ワーナー―ランバート・コンパニー | マトリックスメタロプロテイナーゼ阻害剤およびそれらの治療的使用 |
-
1997
- 1997-03-26 GB GBGB9706255.8A patent/GB9706255D0/en active Pending
-
1998
- 1998-03-16 IL IL13175198A patent/IL131751A0/xx unknown
- 1998-03-16 CA CA002285439A patent/CA2285439A1/en not_active Abandoned
- 1998-03-16 BR BR9808366-0A patent/BR9808366A/pt not_active Application Discontinuation
- 1998-03-16 KR KR1019997008694A patent/KR20010005627A/ko not_active Application Discontinuation
- 1998-03-16 CN CN98803639A patent/CN1251091A/zh active Pending
- 1998-03-16 JP JP54489898A patent/JP2001518922A/ja active Pending
- 1998-03-16 WO PCT/EP1998/001766 patent/WO1998042659A2/en not_active Application Discontinuation
- 1998-03-16 HU HU0003021A patent/HUP0003021A3/hu unknown
- 1998-03-16 PL PL98336039A patent/PL336039A1/xx unknown
- 1998-03-16 AU AU72105/98A patent/AU7210598A/en not_active Abandoned
- 1998-03-16 TR TR1999/02357T patent/TR199902357T2/xx unknown
- 1998-03-16 EP EP98919153A patent/EP0973732A2/en not_active Withdrawn
- 1998-03-16 US US09/381,405 patent/US6242467B1/en not_active Expired - Fee Related
- 1998-03-24 AR ARP980101342A patent/AR012294A1/es unknown
- 1998-03-25 ZA ZA9802517A patent/ZA982517B/xx unknown
- 1998-03-26 CO CO98016978A patent/CO4950563A1/es unknown
-
1999
- 1999-09-24 NO NO994671A patent/NO994671D0/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CO4950563A1 (es) | 2000-09-01 |
| CN1251091A (zh) | 2000-04-19 |
| EP0973732A2 (en) | 2000-01-26 |
| HUP0003021A3 (en) | 2002-02-28 |
| TR199902357T2 (xx) | 2000-05-22 |
| BR9808366A (pt) | 2000-05-23 |
| WO1998042659A3 (en) | 1999-02-25 |
| WO1998042659A2 (en) | 1998-10-01 |
| JP2001518922A (ja) | 2001-10-16 |
| AR012294A1 (es) | 2000-10-18 |
| CA2285439A1 (en) | 1998-10-01 |
| ZA982517B (en) | 1999-09-27 |
| NO994671L (no) | 1999-09-24 |
| NO994671D0 (no) | 1999-09-24 |
| GB9706255D0 (en) | 1997-05-14 |
| AU7210598A (en) | 1998-10-20 |
| US6242467B1 (en) | 2001-06-05 |
| HUP0003021A2 (hu) | 2002-01-28 |
| KR20010005627A (ko) | 2001-01-15 |
| PL336039A1 (en) | 2000-06-05 |
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