NO994671L - Aryl- eller heteroarylsulfonamid-substituerte hydroksamsyrederivater, fremgangsmåte til fremstilling derav og deres anvendelse som farmasöytika - Google Patents
Aryl- eller heteroarylsulfonamid-substituerte hydroksamsyrederivater, fremgangsmåte til fremstilling derav og deres anvendelse som farmasöytikaInfo
- Publication number
- NO994671L NO994671L NO994671A NO994671A NO994671L NO 994671 L NO994671 L NO 994671L NO 994671 A NO994671 A NO 994671A NO 994671 A NO994671 A NO 994671A NO 994671 L NO994671 L NO 994671L
- Authority
- NO
- Norway
- Prior art keywords
- aryl
- heteroarylsulfonamide
- pharmaceuticals
- preparation
- acid derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
- C07C311/19—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
- C07C311/29—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
Forbindelser med formel (I):. hvor R er hydroksy, hydrogen, alkenyl, alkynyl eller aryl og R1 er aryl eller heteroaryl, er nyttige ved behandling og forebyggelse av lidelser mediert av CD23 eller TNF.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9706255.8A GB9706255D0 (en) | 1997-03-26 | 1997-03-26 | Novel compounds |
PCT/EP1998/001766 WO1998042659A2 (en) | 1997-03-26 | 1998-03-16 | Aryl- or heteroarylsulfonamide substituted hydroxamic acid derivates, process for their preparation and their use as pharmaceuticals |
Publications (2)
Publication Number | Publication Date |
---|---|
NO994671L true NO994671L (no) | 1999-09-24 |
NO994671D0 NO994671D0 (no) | 1999-09-24 |
Family
ID=10809882
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO994671A NO994671D0 (no) | 1997-03-26 | 1999-09-24 | Aryl- eller heteroarylsulfonamid-substituerte hydroksamsyrederivater, fremgangsmaate til fremstillint derav og deres anvendelse som farmasöytika |
Country Status (18)
Country | Link |
---|---|
US (1) | US6242467B1 (no) |
EP (1) | EP0973732A2 (no) |
JP (1) | JP2001518922A (no) |
KR (1) | KR20010005627A (no) |
CN (1) | CN1251091A (no) |
AR (1) | AR012294A1 (no) |
AU (1) | AU7210598A (no) |
BR (1) | BR9808366A (no) |
CA (1) | CA2285439A1 (no) |
CO (1) | CO4950563A1 (no) |
GB (1) | GB9706255D0 (no) |
HU (1) | HUP0003021A3 (no) |
IL (1) | IL131751A0 (no) |
NO (1) | NO994671D0 (no) |
PL (1) | PL336039A1 (no) |
TR (1) | TR199902357T2 (no) |
WO (1) | WO1998042659A2 (no) |
ZA (1) | ZA982517B (no) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5904697A (en) * | 1995-02-24 | 1999-05-18 | Heartport, Inc. | Devices and methods for performing a vascular anastomosis |
EP1009737A2 (en) * | 1997-07-31 | 2000-06-21 | The Procter & Gamble Company | Sulfonylamino substituted hydroxamic acid derivatives as metalloprotease inhibitors |
US6403632B1 (en) * | 2000-03-01 | 2002-06-11 | Bristol Myers Squibb Pharma Co | Lactam metalloprotease inhibitors |
US6753337B2 (en) | 1999-01-27 | 2004-06-22 | Wyeth Holdings Corporation | Alkynyl containing hydroxamic acid compounds as matrix metalloproteinase/tace inhibitors |
US6762178B2 (en) | 1999-01-27 | 2004-07-13 | Wyeth Holdings Corporation | Acetylenic aryl sulfonamide and phosphinic acid amide hydroxamic acid TACE inhibitors |
US6340691B1 (en) | 1999-01-27 | 2002-01-22 | American Cyanamid Company | Alkynyl containing hydroxamic acid compounds as matrix metalloproteinase and tace inhibitors |
US6313123B1 (en) | 1999-01-27 | 2001-11-06 | American Cyanamid Company | Acetylenic sulfonamide thiol tace inhibitors |
US6225311B1 (en) | 1999-01-27 | 2001-05-01 | American Cyanamid Company | Acetylenic α-amino acid-based sulfonamide hydroxamic acid tace inhibitors |
US6946473B2 (en) | 1999-01-27 | 2005-09-20 | Wyeth Holdings Corporation | Preparation and use of acetylenic ortho-sulfonamido and phosphinic acid amido bicyclic heteroaryl hydroxamic acids as TACE inhibitors |
US6326516B1 (en) | 1999-01-27 | 2001-12-04 | American Cyanamid Company | Acetylenic β-sulfonamido and phosphinic acid amide hydroxamic acid TACE inhibitors |
CN1178915C (zh) | 1999-01-27 | 2004-12-08 | 惠氏控股有限公司 | 含有炔基的异羟肟酸衍生物、其制备及其作为基质金属蛋白酶抑制剂/TNF-α转变酶抑制剂的用途 |
US6200996B1 (en) | 1999-01-27 | 2001-03-13 | American Cyanamid Company | Heteroaryl acetylenic sulfonamide and phosphinic acid amide hydroxamic acid tace inhibitors |
US6277885B1 (en) | 1999-01-27 | 2001-08-21 | American Cyanamid Company | Acetylenic aryl sulfonamide and phosphinic acid amide hydroxamic acid TACE inhibitors |
WO2000051975A1 (en) | 1999-03-03 | 2000-09-08 | The Procter & Gamble Company | Alkenyl- and alkynyl-containing metalloprotease inhibitors |
CA2366954A1 (en) | 1999-03-03 | 2000-09-08 | The Procter & Gamble Company | Dihetero-substituted metalloprotease inhibitors |
GB9922825D0 (en) * | 1999-09-25 | 1999-11-24 | Smithkline Beecham Biolog | Medical use |
US6808902B1 (en) | 1999-11-12 | 2004-10-26 | Amgen Inc. | Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules |
US20030134880A1 (en) * | 2000-02-24 | 2003-07-17 | Gordon Bruton | Novel cd23 inhibitors |
CN1440400A (zh) * | 2000-05-25 | 2003-09-03 | 史密斯克莱·比奇曼公司 | 二环基或杂二环基甲磺酰氨基-取代的n-羟基甲酰胺化合物 |
MXPA04000134A (es) | 2001-06-26 | 2005-06-06 | Abgenix Inc | Anticuerpos para ligandos de osteoprotegerina. |
JP2005507937A (ja) | 2001-11-01 | 2005-03-24 | ワイス・ホールディングズ・コーポレイション | マトリックスメタロプロテイナーゼおよびtace阻害剤としてのアレンアリールスルホンアミドヒドロキサム酸 |
GB0128376D0 (en) * | 2001-11-27 | 2002-01-16 | Smithkline Beecham Plc | Novel compounds |
DE60233688D1 (de) * | 2001-12-27 | 2009-10-22 | Lg Electronics Inc | Waschmaschine |
ES2323527T3 (es) | 2002-05-29 | 2009-07-20 | MERCK & CO., INC. | Compuestos utiles en el tratamiento del carbunco y en la inhibicion del factor letal. |
WO2005021489A2 (en) | 2002-12-23 | 2005-03-10 | Wyeth Holdings Corporation | Acetylenic aryl sulfonate hydroxamic acid tace and matrix metalloproteinase inhibitors |
EP1747212A4 (en) | 2004-05-11 | 2009-03-25 | Merck & Co Inc | PROCESS FOR PRODUCING N-SULFINATED AMINO ACID DERIVATIVES |
WO2010007027A1 (en) * | 2008-07-14 | 2010-01-21 | Novartis Ag | Selective hydroxamic acid based mmp-12 and mmp-13 inhibitors |
USD810196S1 (en) * | 2015-04-14 | 2018-02-13 | Marcia D. Fackler | Sunglass book cover |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5455258A (en) * | 1993-01-06 | 1995-10-03 | Ciba-Geigy Corporation | Arylsulfonamido-substituted hydroxamic acids |
CA2193691A1 (en) * | 1994-06-22 | 1995-12-28 | Andrew Miller | Metalloproteinase inhibitors |
GB9414157D0 (en) | 1994-07-13 | 1994-08-31 | Smithkline Beecham Plc | Medical use |
KR19990036271A (ko) * | 1995-08-08 | 1999-05-25 | 토마스 네프 | 콜라겐 과다생산과 연관된 질환의 치료에 이용되는 c-프로테나제 저해물질 |
DK0757984T3 (da) | 1995-08-08 | 2003-03-03 | Ono Pharmaceutical Co | Hydroxamsyrederivater, der kan anvendes til inhibering af gelatinase |
DE69707865T2 (de) | 1996-05-17 | 2002-05-02 | Warner-Lambert Co., Morris Plains | Biphenylsulfonamid matrix metalloproteinase inhibitoren |
NZ333063A (en) * | 1996-09-04 | 2000-12-22 | Warner Lambert Co | Dibenzofuran sulfonamide derivatives as matrix metalloproteinase inhibitors |
-
1997
- 1997-03-26 GB GBGB9706255.8A patent/GB9706255D0/en active Pending
-
1998
- 1998-03-16 CA CA002285439A patent/CA2285439A1/en not_active Abandoned
- 1998-03-16 TR TR1999/02357T patent/TR199902357T2/xx unknown
- 1998-03-16 IL IL13175198A patent/IL131751A0/xx unknown
- 1998-03-16 BR BR9808366-0A patent/BR9808366A/pt not_active Application Discontinuation
- 1998-03-16 US US09/381,405 patent/US6242467B1/en not_active Expired - Fee Related
- 1998-03-16 AU AU72105/98A patent/AU7210598A/en not_active Abandoned
- 1998-03-16 KR KR1019997008694A patent/KR20010005627A/ko not_active Application Discontinuation
- 1998-03-16 PL PL98336039A patent/PL336039A1/xx unknown
- 1998-03-16 HU HU0003021A patent/HUP0003021A3/hu unknown
- 1998-03-16 JP JP54489898A patent/JP2001518922A/ja active Pending
- 1998-03-16 CN CN98803639A patent/CN1251091A/zh active Pending
- 1998-03-16 WO PCT/EP1998/001766 patent/WO1998042659A2/en not_active Application Discontinuation
- 1998-03-16 EP EP98919153A patent/EP0973732A2/en not_active Withdrawn
- 1998-03-24 AR ARP980101342A patent/AR012294A1/es unknown
- 1998-03-25 ZA ZA9802517A patent/ZA982517B/xx unknown
- 1998-03-26 CO CO98016978A patent/CO4950563A1/es unknown
-
1999
- 1999-09-24 NO NO994671A patent/NO994671D0/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO1998042659A2 (en) | 1998-10-01 |
PL336039A1 (en) | 2000-06-05 |
EP0973732A2 (en) | 2000-01-26 |
ZA982517B (en) | 1999-09-27 |
KR20010005627A (ko) | 2001-01-15 |
HUP0003021A2 (hu) | 2002-01-28 |
BR9808366A (pt) | 2000-05-23 |
WO1998042659A3 (en) | 1999-02-25 |
JP2001518922A (ja) | 2001-10-16 |
TR199902357T2 (xx) | 2000-05-22 |
CA2285439A1 (en) | 1998-10-01 |
HUP0003021A3 (en) | 2002-02-28 |
IL131751A0 (en) | 2001-03-19 |
GB9706255D0 (en) | 1997-05-14 |
AU7210598A (en) | 1998-10-20 |
NO994671D0 (no) | 1999-09-24 |
AR012294A1 (es) | 2000-10-18 |
CO4950563A1 (es) | 2000-09-01 |
CN1251091A (zh) | 2000-04-19 |
US6242467B1 (en) | 2001-06-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |