ZA982517B - Novel inhibitors of the formation of soluble CD23 in humans. - Google Patents
Novel inhibitors of the formation of soluble CD23 in humans.Info
- Publication number
- ZA982517B ZA982517B ZA9802517A ZA982517A ZA982517B ZA 982517 B ZA982517 B ZA 982517B ZA 9802517 A ZA9802517 A ZA 9802517A ZA 982517 A ZA982517 A ZA 982517A ZA 982517 B ZA982517 B ZA 982517B
- Authority
- ZA
- South Africa
- Prior art keywords
- humans
- soluble
- formation
- novel inhibitors
- inhibitors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
- C07C311/19—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
- C07C311/29—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9706255.8A GB9706255D0 (en) | 1997-03-26 | 1997-03-26 | Novel compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA982517B true ZA982517B (en) | 1999-09-27 |
Family
ID=10809882
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA9802517A ZA982517B (en) | 1997-03-26 | 1998-03-25 | Novel inhibitors of the formation of soluble CD23 in humans. |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US6242467B1 (xx) |
| EP (1) | EP0973732A2 (xx) |
| JP (1) | JP2001518922A (xx) |
| KR (1) | KR20010005627A (xx) |
| CN (1) | CN1251091A (xx) |
| AR (1) | AR012294A1 (xx) |
| AU (1) | AU7210598A (xx) |
| BR (1) | BR9808366A (xx) |
| CA (1) | CA2285439A1 (xx) |
| CO (1) | CO4950563A1 (xx) |
| GB (1) | GB9706255D0 (xx) |
| HU (1) | HUP0003021A3 (xx) |
| IL (1) | IL131751A0 (xx) |
| NO (1) | NO994671D0 (xx) |
| PL (1) | PL336039A1 (xx) |
| TR (1) | TR199902357T2 (xx) |
| WO (1) | WO1998042659A2 (xx) |
| ZA (1) | ZA982517B (xx) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5904697A (en) * | 1995-02-24 | 1999-05-18 | Heartport, Inc. | Devices and methods for performing a vascular anastomosis |
| BR9810841A (pt) | 1997-07-31 | 2001-07-10 | Procter & Gamble | Inibidores de metaloprotease alicìclicos |
| US6403632B1 (en) * | 2000-03-01 | 2002-06-11 | Bristol Myers Squibb Pharma Co | Lactam metalloprotease inhibitors |
| US6313123B1 (en) | 1999-01-27 | 2001-11-06 | American Cyanamid Company | Acetylenic sulfonamide thiol tace inhibitors |
| US6946473B2 (en) | 1999-01-27 | 2005-09-20 | Wyeth Holdings Corporation | Preparation and use of acetylenic ortho-sulfonamido and phosphinic acid amido bicyclic heteroaryl hydroxamic acids as TACE inhibitors |
| US6277885B1 (en) | 1999-01-27 | 2001-08-21 | American Cyanamid Company | Acetylenic aryl sulfonamide and phosphinic acid amide hydroxamic acid TACE inhibitors |
| US6762178B2 (en) | 1999-01-27 | 2004-07-13 | Wyeth Holdings Corporation | Acetylenic aryl sulfonamide and phosphinic acid amide hydroxamic acid TACE inhibitors |
| US6340691B1 (en) | 1999-01-27 | 2002-01-22 | American Cyanamid Company | Alkynyl containing hydroxamic acid compounds as matrix metalloproteinase and tace inhibitors |
| US6326516B1 (en) | 1999-01-27 | 2001-12-04 | American Cyanamid Company | Acetylenic β-sulfonamido and phosphinic acid amide hydroxamic acid TACE inhibitors |
| US6753337B2 (en) | 1999-01-27 | 2004-06-22 | Wyeth Holdings Corporation | Alkynyl containing hydroxamic acid compounds as matrix metalloproteinase/tace inhibitors |
| US6225311B1 (en) | 1999-01-27 | 2001-05-01 | American Cyanamid Company | Acetylenic α-amino acid-based sulfonamide hydroxamic acid tace inhibitors |
| US6200996B1 (en) | 1999-01-27 | 2001-03-13 | American Cyanamid Company | Heteroaryl acetylenic sulfonamide and phosphinic acid amide hydroxamic acid tace inhibitors |
| US6358980B1 (en) | 1999-01-27 | 2002-03-19 | American Cyanamid Company | Alkynyl containing hydroxamic acid compounds as matrix metalloproteinase/tace inhibitors |
| IL145085A0 (en) | 1999-03-03 | 2002-06-30 | Procter & Gamble | Dihetero-substituted metalloprotease inhibitors |
| PL350340A1 (en) | 1999-03-03 | 2002-12-02 | Procter & Gamble | Alkenyl- and alkynyl-containing metalloprotease inhibitors |
| GB9922825D0 (en) * | 1999-09-25 | 1999-11-24 | Smithkline Beecham Biolog | Medical use |
| US6808902B1 (en) | 1999-11-12 | 2004-10-26 | Amgen Inc. | Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules |
| JP2003523994A (ja) * | 2000-02-24 | 2003-08-12 | スミスクライン ビーチャム パブリック リミテッド カンパニー | 新規ｃｄ２３インヒビター |
| BR0111074A (pt) * | 2000-05-25 | 2003-06-24 | Smithkline Beecham Plc | N-hidroxiformamidas biciclil ou heterobiciclilme-tanossulfonilamino-substituìdos |
| BRPI0210579B8 (pt) | 2001-06-26 | 2021-05-25 | Amgen Fremont Inc | anticorpo e composição farmacêutica |
| EP1440057A1 (en) | 2001-11-01 | 2004-07-28 | Wyeth Holdings Corporation | Allenic aryl sulfonamide hydroxamic acids as matrix metalloproteinase and tace inhibitors |
| GB0128376D0 (en) * | 2001-11-27 | 2002-01-16 | Smithkline Beecham Plc | Novel compounds |
| CN1309894C (zh) * | 2001-12-27 | 2007-04-11 | Lg电子株式会社 | 洗衣机 |
| UA76059C2 (en) * | 2002-05-29 | 2006-06-15 | Merck & Co Inc | Compounds used for treating anthrax or inhibiting lethal factor |
| WO2005021489A2 (en) | 2002-12-23 | 2005-03-10 | Wyeth Holdings Corporation | Acetylenic aryl sulfonate hydroxamic acid tace and matrix metalloproteinase inhibitors |
| CA2566191A1 (en) | 2004-05-11 | 2005-12-15 | Merck & Co., Inc. | Process for making n-sulfonated-amino acid derivatives |
| CN102143942A (zh) * | 2008-07-14 | 2011-08-03 | 诺瓦提斯公司 | 选择性的基于异羟肟酸的mmp-12 和mmp-13 抑制剂 |
| USD810196S1 (en) * | 2015-04-14 | 2018-02-13 | Marcia D. Fackler | Sunglass book cover |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5455258A (en) | 1993-01-06 | 1995-10-03 | Ciba-Geigy Corporation | Arylsulfonamido-substituted hydroxamic acids |
| CN1151157A (zh) * | 1994-06-22 | 1997-06-04 | 英国生物技术药物有限公司 | 金属蛋白酶抑制剂 |
| GB9414157D0 (en) * | 1994-07-13 | 1994-08-31 | Smithkline Beecham Plc | Medical use |
| BR9609883A (pt) | 1995-08-08 | 1999-03-23 | Fibrogen Inc | Composto tendo efeito inibidor em proteinase c composição farmacéutica e processo para tratar doenças relacionadas com a produção inapropriada ou desregulada de colágeno |
| DE69624536T2 (de) | 1995-08-08 | 2003-06-05 | Ono Pharmaceutical Co | Hydroxamsäurederivate verwendbar zur Hemmung von Gelatinase |
| KR20000011095A (ko) | 1996-05-17 | 2000-02-25 | 로즈 암스트롱, 크리스틴 에이. 트러트웨인 | 비페닐술폰아미드 매트릭스 메탈로프로테이나아제 억제제 |
| BR9711988A (pt) * | 1996-09-04 | 1999-08-24 | Warner Lambert Co | Inibidores de metaloproteinase de matriz e seus empregos terap-uticos |
-
1997
- 1997-03-26 GB GBGB9706255.8A patent/GB9706255D0/en active Pending
-
1998
- 1998-03-16 EP EP98919153A patent/EP0973732A2/en not_active Withdrawn
- 1998-03-16 IL IL13175198A patent/IL131751A0/xx unknown
- 1998-03-16 AU AU72105/98A patent/AU7210598A/en not_active Abandoned
- 1998-03-16 CN CN98803639A patent/CN1251091A/zh active Pending
- 1998-03-16 JP JP54489898A patent/JP2001518922A/ja active Pending
- 1998-03-16 US US09/381,405 patent/US6242467B1/en not_active Expired - Fee Related
- 1998-03-16 HU HU0003021A patent/HUP0003021A3/hu unknown
- 1998-03-16 WO PCT/EP1998/001766 patent/WO1998042659A2/en not_active Application Discontinuation
- 1998-03-16 PL PL98336039A patent/PL336039A1/xx unknown
- 1998-03-16 CA CA002285439A patent/CA2285439A1/en not_active Abandoned
- 1998-03-16 TR TR1999/02357T patent/TR199902357T2/xx unknown
- 1998-03-16 KR KR1019997008694A patent/KR20010005627A/ko not_active Application Discontinuation
- 1998-03-16 BR BR9808366-0A patent/BR9808366A/pt not_active Application Discontinuation
- 1998-03-24 AR ARP980101342A patent/AR012294A1/es unknown
- 1998-03-25 ZA ZA9802517A patent/ZA982517B/xx unknown
- 1998-03-26 CO CO98016978A patent/CO4950563A1/es unknown
-
1999
- 1999-09-24 NO NO994671A patent/NO994671D0/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU7210598A (en) | 1998-10-20 |
| GB9706255D0 (en) | 1997-05-14 |
| AR012294A1 (es) | 2000-10-18 |
| US6242467B1 (en) | 2001-06-05 |
| WO1998042659A2 (en) | 1998-10-01 |
| NO994671L (no) | 1999-09-24 |
| WO1998042659A3 (en) | 1999-02-25 |
| NO994671D0 (no) | 1999-09-24 |
| TR199902357T2 (xx) | 2000-05-22 |
| HUP0003021A2 (hu) | 2002-01-28 |
| PL336039A1 (en) | 2000-06-05 |
| CN1251091A (zh) | 2000-04-19 |
| CA2285439A1 (en) | 1998-10-01 |
| JP2001518922A (ja) | 2001-10-16 |
| EP0973732A2 (en) | 2000-01-26 |
| BR9808366A (pt) | 2000-05-23 |
| HUP0003021A3 (en) | 2002-02-28 |
| KR20010005627A (ko) | 2001-01-15 |
| CO4950563A1 (es) | 2000-09-01 |
| IL131751A0 (en) | 2001-03-19 |
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