ZA982517B - Novel inhibitors of the formation of soluble CD23 in humans. - Google Patents
Novel inhibitors of the formation of soluble CD23 in humans.Info
- Publication number
- ZA982517B ZA982517B ZA9802517A ZA982517A ZA982517B ZA 982517 B ZA982517 B ZA 982517B ZA 9802517 A ZA9802517 A ZA 9802517A ZA 982517 A ZA982517 A ZA 982517A ZA 982517 B ZA982517 B ZA 982517B
- Authority
- ZA
- South Africa
- Prior art keywords
- humans
- soluble
- formation
- novel inhibitors
- inhibitors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
- C07C311/19—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
- C07C311/29—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9706255.8A GB9706255D0 (en) | 1997-03-26 | 1997-03-26 | Novel compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA982517B true ZA982517B (en) | 1999-09-27 |
Family
ID=10809882
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA9802517A ZA982517B (en) | 1997-03-26 | 1998-03-25 | Novel inhibitors of the formation of soluble CD23 in humans. |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US6242467B1 (hu) |
| EP (1) | EP0973732A2 (hu) |
| JP (1) | JP2001518922A (hu) |
| KR (1) | KR20010005627A (hu) |
| CN (1) | CN1251091A (hu) |
| AR (1) | AR012294A1 (hu) |
| AU (1) | AU7210598A (hu) |
| BR (1) | BR9808366A (hu) |
| CA (1) | CA2285439A1 (hu) |
| CO (1) | CO4950563A1 (hu) |
| GB (1) | GB9706255D0 (hu) |
| HU (1) | HUP0003021A3 (hu) |
| IL (1) | IL131751A0 (hu) |
| NO (1) | NO994671L (hu) |
| PL (1) | PL336039A1 (hu) |
| TR (1) | TR199902357T2 (hu) |
| WO (1) | WO1998042659A2 (hu) |
| ZA (1) | ZA982517B (hu) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5904697A (en) * | 1995-02-24 | 1999-05-18 | Heartport, Inc. | Devices and methods for performing a vascular anastomosis |
| HUP0004595A3 (en) | 1997-07-31 | 2001-12-28 | Procter & Gamble | Acyclic metalloprotease inhibitors |
| US6403632B1 (en) * | 2000-03-01 | 2002-06-11 | Bristol Myers Squibb Pharma Co | Lactam metalloprotease inhibitors |
| CN1178915C (zh) | 1999-01-27 | 2004-12-08 | 惠氏控股有限公司 | 含有炔基的异羟肟酸衍生物、其制备及其作为基质金属蛋白酶抑制剂/TNF-α转变酶抑制剂的用途 |
| US6946473B2 (en) | 1999-01-27 | 2005-09-20 | Wyeth Holdings Corporation | Preparation and use of acetylenic ortho-sulfonamido and phosphinic acid amido bicyclic heteroaryl hydroxamic acids as TACE inhibitors |
| US6762178B2 (en) | 1999-01-27 | 2004-07-13 | Wyeth Holdings Corporation | Acetylenic aryl sulfonamide and phosphinic acid amide hydroxamic acid TACE inhibitors |
| US6753337B2 (en) | 1999-01-27 | 2004-06-22 | Wyeth Holdings Corporation | Alkynyl containing hydroxamic acid compounds as matrix metalloproteinase/tace inhibitors |
| US6200996B1 (en) | 1999-01-27 | 2001-03-13 | American Cyanamid Company | Heteroaryl acetylenic sulfonamide and phosphinic acid amide hydroxamic acid tace inhibitors |
| US6277885B1 (en) | 1999-01-27 | 2001-08-21 | American Cyanamid Company | Acetylenic aryl sulfonamide and phosphinic acid amide hydroxamic acid TACE inhibitors |
| US6340691B1 (en) | 1999-01-27 | 2002-01-22 | American Cyanamid Company | Alkynyl containing hydroxamic acid compounds as matrix metalloproteinase and tace inhibitors |
| US6326516B1 (en) | 1999-01-27 | 2001-12-04 | American Cyanamid Company | Acetylenic β-sulfonamido and phosphinic acid amide hydroxamic acid TACE inhibitors |
| US6225311B1 (en) | 1999-01-27 | 2001-05-01 | American Cyanamid Company | Acetylenic α-amino acid-based sulfonamide hydroxamic acid tace inhibitors |
| US6313123B1 (en) | 1999-01-27 | 2001-11-06 | American Cyanamid Company | Acetylenic sulfonamide thiol tace inhibitors |
| US6566381B1 (en) | 1999-03-03 | 2003-05-20 | The Procter & Gamble Company | Hetero-substituted metalloprotease inhibitors |
| IL145089A0 (en) | 1999-03-03 | 2002-06-30 | Procter & Gamble | Alkenyl-and alkynyl-containing metalloprotease inhibitors |
| GB9922825D0 (en) * | 1999-09-25 | 1999-11-24 | Smithkline Beecham Biolog | Medical use |
| US6808902B1 (en) | 1999-11-12 | 2004-10-26 | Amgen Inc. | Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules |
| US20030134880A1 (en) * | 2000-02-24 | 2003-07-17 | Gordon Bruton | Novel cd23 inhibitors |
| US20040024066A1 (en) * | 2000-05-25 | 2004-02-05 | Best Desmond John | Bicyclyl or heterobicyclylmethanesulfonylamino-substituted n-hydroxyformamides |
| DK2295081T3 (en) | 2001-06-26 | 2019-02-18 | Amgen Inc | Antibodies to OPGL |
| WO2003037852A1 (en) | 2001-11-01 | 2003-05-08 | Wyeth Holdings Corporation | Allenic aryl sulfonamide hydroxamic acids as matrix metalloproteinase and tace inhibitors |
| GB0128376D0 (en) * | 2001-11-27 | 2002-01-16 | Smithkline Beecham Plc | Novel compounds |
| WO2003056094A1 (en) * | 2001-12-27 | 2003-07-10 | Lg Electronics Inc. | Washing machine |
| NZ536189A (en) | 2002-05-29 | 2007-08-31 | Merck & Co Inc | Methylphenylsulfonyl amide derivative compounds useful in the treatment of anthrax and inhibiting lethal factor |
| AU2003304456A1 (en) | 2002-12-23 | 2005-03-16 | Wyeth Holdings Corporation | Acetylenic aryl sulfonate hydroxamic acid tace and matrix metalloproteinase inhibitors |
| EP1747212A4 (en) | 2004-05-11 | 2009-03-25 | Merck & Co Inc | PROCESS FOR PRODUCING N-SULFINATED AMINO ACID DERIVATIVES |
| BRPI0915762A2 (pt) * | 2008-07-14 | 2015-11-03 | Novartis Ag | inibidores de mmp-12 e mmp-13 com base em ácido hidroxâmico seletivo |
| USD810196S1 (en) * | 2015-04-14 | 2018-02-13 | Marcia D. Fackler | Sunglass book cover |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5455258A (en) * | 1993-01-06 | 1995-10-03 | Ciba-Geigy Corporation | Arylsulfonamido-substituted hydroxamic acids |
| GB2303850B (en) | 1994-06-22 | 1998-06-10 | British Biotech Pharm | Metalloproteinase inhibitors |
| GB9414157D0 (en) * | 1994-07-13 | 1994-08-31 | Smithkline Beecham Plc | Medical use |
| EP0757984B1 (en) | 1995-08-08 | 2002-10-30 | Ono Pharmaceutical Co., Ltd. | Hydroxamic acid derivatives useful for inhibiting gelatinase |
| CN1198096A (zh) | 1995-08-08 | 1998-11-04 | 菲布洛根有限公司 | 用于治疗与胶原蛋白过量产生有关的疾病的c－蛋白酶抑制剂 |
| SK282863B6 (sk) * | 1996-05-17 | 2002-12-03 | Warner-Lambert Company | Bifenylsulfonamidy, ich použitie a farmaceutické prostriedky na ich báze |
| EP0931045A1 (en) | 1996-09-04 | 1999-07-28 | Warner-Lambert Company | Matrix metalloproteinase inhibitors and their therapeutic uses |
-
1997
- 1997-03-26 GB GBGB9706255.8A patent/GB9706255D0/en active Pending
-
1998
- 1998-03-16 WO PCT/EP1998/001766 patent/WO1998042659A2/en not_active Application Discontinuation
- 1998-03-16 HU HU0003021A patent/HUP0003021A3/hu unknown
- 1998-03-16 CA CA002285439A patent/CA2285439A1/en not_active Abandoned
- 1998-03-16 TR TR1999/02357T patent/TR199902357T2/xx unknown
- 1998-03-16 JP JP54489898A patent/JP2001518922A/ja active Pending
- 1998-03-16 EP EP98919153A patent/EP0973732A2/en not_active Withdrawn
- 1998-03-16 US US09/381,405 patent/US6242467B1/en not_active Expired - Fee Related
- 1998-03-16 CN CN98803639A patent/CN1251091A/zh active Pending
- 1998-03-16 BR BR9808366-0A patent/BR9808366A/pt not_active Application Discontinuation
- 1998-03-16 IL IL13175198A patent/IL131751A0/xx unknown
- 1998-03-16 PL PL98336039A patent/PL336039A1/xx unknown
- 1998-03-16 KR KR1019997008694A patent/KR20010005627A/ko not_active Application Discontinuation
- 1998-03-16 AU AU72105/98A patent/AU7210598A/en not_active Abandoned
- 1998-03-24 AR ARP980101342A patent/AR012294A1/es unknown
- 1998-03-25 ZA ZA9802517A patent/ZA982517B/xx unknown
- 1998-03-26 CO CO98016978A patent/CO4950563A1/es unknown
-
1999
- 1999-09-24 NO NO994671A patent/NO994671L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| HUP0003021A3 (en) | 2002-02-28 |
| GB9706255D0 (en) | 1997-05-14 |
| EP0973732A2 (en) | 2000-01-26 |
| PL336039A1 (en) | 2000-06-05 |
| CN1251091A (zh) | 2000-04-19 |
| WO1998042659A2 (en) | 1998-10-01 |
| NO994671D0 (no) | 1999-09-24 |
| AU7210598A (en) | 1998-10-20 |
| AR012294A1 (es) | 2000-10-18 |
| BR9808366A (pt) | 2000-05-23 |
| WO1998042659A3 (en) | 1999-02-25 |
| IL131751A0 (en) | 2001-03-19 |
| US6242467B1 (en) | 2001-06-05 |
| HUP0003021A2 (hu) | 2002-01-28 |
| KR20010005627A (ko) | 2001-01-15 |
| TR199902357T2 (xx) | 2000-05-22 |
| JP2001518922A (ja) | 2001-10-16 |
| CO4950563A1 (es) | 2000-09-01 |
| NO994671L (no) | 1999-09-24 |
| CA2285439A1 (en) | 1998-10-01 |
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