IL130484A - History of -16N-Vitamin-D - Google Patents

History of -16N-Vitamin-D

Info

Publication number
IL130484A
IL130484A IL13048497A IL13048497A IL130484A IL 130484 A IL130484 A IL 130484A IL 13048497 A IL13048497 A IL 13048497A IL 13048497 A IL13048497 A IL 13048497A IL 130484 A IL130484 A IL 130484A
Authority
IL
Israel
Prior art keywords
hydroxy
dihydroxy
ethyl
brs
tetraene
Prior art date
Application number
IL13048497A
Other languages
English (en)
Hebrew (he)
Other versions
IL130484A0 (en
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of IL130484A0 publication Critical patent/IL130484A0/xx
Publication of IL130484A publication Critical patent/IL130484A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/0065—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by an OH group free esterified or etherified
    • C07J7/007—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by an OH group free esterified or etherified not substituted in position 17 alfa
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL13048497A 1996-12-20 1997-12-19 History of -16N-Vitamin-D IL130484A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP34178696 1996-12-20
PCT/JP1997/004715 WO1998028266A1 (fr) 1996-12-20 1997-12-19 Derives de vitamine d 16-ene

Publications (2)

Publication Number Publication Date
IL130484A0 IL130484A0 (en) 2000-06-01
IL130484A true IL130484A (en) 2004-07-25

Family

ID=18348753

Family Applications (2)

Application Number Title Priority Date Filing Date
IL17189097A IL161890A0 (en) 1996-12-20 1997-12-19 16-Ene-vitamin d derivatives
IL13048497A IL130484A (en) 1996-12-20 1997-12-19 History of -16N-Vitamin-D

Family Applications Before (1)

Application Number Title Priority Date Filing Date
IL17189097A IL161890A0 (en) 1996-12-20 1997-12-19 16-Ene-vitamin d derivatives

Country Status (13)

Country Link
US (3) US6326503B1 (ja)
EP (1) EP0947504B1 (ja)
KR (2) KR20050123185A (ja)
AT (1) ATE248814T1 (ja)
AU (1) AU720454B2 (ja)
CA (1) CA2275382A1 (ja)
DE (1) DE69724646T2 (ja)
DK (1) DK0947504T3 (ja)
ES (1) ES2206758T3 (ja)
IL (2) IL161890A0 (ja)
NO (1) NO992981L (ja)
PT (1) PT947504E (ja)
WO (1) WO1998028266A1 (ja)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010007907A1 (en) * 1997-05-16 2001-07-12 Women And Infants Hospital 3-epi compounds of vitamin d3 and uses thereof
IL144726A0 (en) * 1999-02-18 2002-06-30 Chugai Pharmaceutical Co Ltd Method for screening compound having affinity for vitamin d receptor
US6960576B2 (en) 1999-09-13 2005-11-01 Bristol-Myers Squibb Pharma Company Hydroxyalkanoylaminolactams and related structures as inhibitors of Aβ protein production
WO2001079166A1 (fr) * 2000-04-19 2001-10-25 Chugai Seiyaku Kabushiki Kaisha Derives de la vitamine d
ES2364623T3 (es) * 2000-06-15 2011-09-08 Chugai Seiyaku Kabushiki Kaisha Derivados de vitamina d que poseen un átomo 22-oxa o 22-tia, una cadena lateral c17 sustituida con un grupo ácido, éster o amida y un enlace doble 16(17).
CA2664720C (en) 2000-06-15 2011-11-22 Chugai Seiyaku Kabushiki Kaisha Vitamin d derivatives
WO2006051106A1 (en) 2004-11-12 2006-05-18 Bioxell Spa Combined use of vitamin d derivatives and anti-proliferative agents for treating bladder cancer
JP4961562B2 (ja) * 2005-03-04 2012-06-27 国立大学法人 東京医科歯科大学 １９−ノルビタミンｄ誘導体
EP1961740B1 (en) * 2005-11-30 2013-04-24 Chugai Seiyaku Kabushiki Kaisha Method for producing vitamin d derivative utilizing photoreaction
KR20150036717A (ko) 2006-06-02 2015-04-07 니뽄 신야쿠 가부시키가이샤 9,10-세코프레그난 유도체 및 의약
SG173119A1 (en) 2009-01-27 2011-08-29 Berg Biosystems Llc Vitamin d3 and analogs thereof for alleviating side effects associated with chemotherapy
BR112012003372A2 (pt) 2009-08-14 2019-09-24 Berg Biosystems Llc vitamina d3 e análogos da mesma para o tratamento de alopecia.
US9290447B2 (en) 2011-05-03 2016-03-22 Wisconsin Alumni Research Foundation (20R) and (20S)-24-(p-toluenesulfonyloxy)-25,26,27-trinorvitamin D3 analogs and their uses
EP3003497B1 (en) 2013-05-29 2024-02-14 BPGbio, Inc. Preventing or mitigating chemotherapy induced alopecia using vitamin d
CN106279239B (zh) * 2015-05-29 2019-06-28 上海彩迩文生化科技有限公司 多烯化合物、制备方法及其应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9007236D0 (en) * 1990-03-30 1990-05-30 Leo Pharm Prod Ltd Chemical compounds
JPH0680626A (ja) * 1991-05-09 1994-03-22 Chugai Pharmaceut Co Ltd 新規な２２−オキサビタミンｄ誘導体
GB9226877D0 (en) * 1992-12-23 1993-02-17 Leo Pharm Prod Ltd Chemical compounds
JP3415877B2 (ja) * 1993-03-05 2003-06-09 中外製薬株式会社 ２２−オキサビタミンｄ誘導体
US5401733A (en) * 1993-10-01 1995-03-28 Hoffmann-La Roche Inc. Stable and active metabolites of 1,25-dihydroxy-16-ene-cholecalciferol
US5428029A (en) * 1993-11-24 1995-06-27 Hoffmann-La Roche Inc. Vitamin D3 fluorinated analogs
US6121469A (en) * 1993-12-23 2000-09-19 The Regents Of The University Of California Therapeutically effective 1α,25-dihydroxyvitamin D3 analogs
KR100244060B1 (ko) * 1994-04-11 2000-02-01 나가야마 오사무 22-티아비타민 디3 유도체
JP3759639B2 (ja) * 1994-04-11 2006-03-29 中外製薬株式会社 ２２−チアビタミン▲ｄ３▼誘導体
PE28297A1 (es) * 1995-01-26 1997-08-20 Hoffmann La Roche Empleo dermatologico de derivados de vitamina d
JP3715673B2 (ja) * 1995-03-10 2005-11-09 中外製薬株式会社 ビタミンｄ合成中間体の製造方法
US5939408A (en) * 1996-05-23 1999-08-17 Hoffman-La Roche Inc. Vitamin D3 analogs

Also Published As

Publication number Publication date
DE69724646D1 (de) 2003-10-09
US6433200B1 (en) 2002-08-13
AU7872798A (en) 1998-07-17
NO992981L (no) 1999-08-18
DK0947504T3 (da) 2003-11-24
WO1998028266A1 (fr) 1998-07-02
KR100573234B1 (ko) 2006-04-24
PT947504E (pt) 2003-12-31
KR20000057692A (ko) 2000-09-25
US20020032340A1 (en) 2002-03-14
US6555699B2 (en) 2003-04-29
IL161890A0 (en) 2005-11-20
CA2275382A1 (en) 1998-07-02
EP0947504A4 (ja) 1999-11-17
NO992981D0 (no) 1999-06-17
AU720454B2 (en) 2000-06-01
DE69724646T2 (de) 2004-06-17
ATE248814T1 (de) 2003-09-15
US6326503B1 (en) 2001-12-04
ES2206758T3 (es) 2004-05-16
EP0947504A1 (en) 1999-10-06
IL130484A0 (en) 2000-06-01
EP0947504B1 (en) 2003-09-03
US20020193616A1 (en) 2002-12-19
KR20050123185A (ko) 2005-12-29

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees