IL129892A0 - Prodrug forms and new analogues of camptothecin and their use as medicaments - Google Patents
Prodrug forms and new analogues of camptothecin and their use as medicamentsInfo
- Publication number
- IL129892A0 IL129892A0 IL12989297A IL12989297A IL129892A0 IL 129892 A0 IL129892 A0 IL 129892A0 IL 12989297 A IL12989297 A IL 12989297A IL 12989297 A IL12989297 A IL 12989297A IL 129892 A0 IL129892 A0 IL 129892A0
- Authority
- IL
- Israel
- Prior art keywords
- camptothecin
- medicaments
- prodrug forms
- new analogues
- analogues
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9615775A FR2757515B1 (fr) | 1996-12-20 | 1996-12-20 | Formes prodrogues et nouveaux analogues de la camptothecine, leurs procedes de preparation, leur application comme medicaments et les compositions pharmaceutiques les contenant |
FR9615945 | 1996-12-24 | ||
PCT/FR1997/002217 WO1998028304A1 (fr) | 1996-12-20 | 1997-12-05 | Formes prodrogues et analogues de la camptothecine, leur application comme medicaments |
Publications (1)
Publication Number | Publication Date |
---|---|
IL129892A0 true IL129892A0 (en) | 2000-02-29 |
Family
ID=26233188
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL12989297A IL129892A0 (en) | 1996-12-20 | 1997-12-05 | Prodrug forms and new analogues of camptothecin and their use as medicaments |
IL129892A IL129892A (en) | 1996-12-20 | 1999-05-11 | History of Homologues of Campacetcin, their Preparation and Pharmaceutical Preparations Containing Them |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL129892A IL129892A (en) | 1996-12-20 | 1999-05-11 | History of Homologues of Campacetcin, their Preparation and Pharmaceutical Preparations Containing Them |
Country Status (24)
Country | Link |
---|---|
EP (1) | EP0946566B1 (pt) |
JP (1) | JP3576174B2 (pt) |
KR (1) | KR100516873B1 (pt) |
CN (1) | CN1090634C (pt) |
AR (1) | AR005849A1 (pt) |
AT (1) | ATE253582T1 (pt) |
AU (1) | AU734512B2 (pt) |
BR (1) | BR9713977B1 (pt) |
CA (1) | CA2275345C (pt) |
CZ (1) | CZ299794B6 (pt) |
DE (1) | DE69726007T2 (pt) |
DK (1) | DK0946566T3 (pt) |
ES (1) | ES2206760T3 (pt) |
HK (1) | HK1024694A1 (pt) |
HU (1) | HUP0001385A3 (pt) |
IL (2) | IL129892A0 (pt) |
MY (1) | MY122042A (pt) |
NO (1) | NO324973B1 (pt) |
NZ (1) | NZ335938A (pt) |
PL (1) | PL188109B1 (pt) |
PT (1) | PT946566E (pt) |
TW (1) | TW410224B (pt) |
UA (1) | UA57757C2 (pt) |
WO (1) | WO1998028304A1 (pt) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2790261B1 (fr) | 1999-02-26 | 2004-09-10 | Sod Conseils Rech Applic | Nouveaux analogues optiquement purs de la camptothecine et leurs procedes de preparation |
US6150539A (en) * | 1998-09-02 | 2000-11-21 | Pharmagenesis, Inc. | Triptolide prodrugs having high aqueous solubility |
US6207832B1 (en) * | 1999-04-09 | 2001-03-27 | University Of Pittsburgh | Camptothecin analogs and methods of preparation thereof |
FR2801309B1 (fr) * | 1999-11-18 | 2002-01-04 | Adir | Nouveaux composes analogues de la camptothecine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
US6350756B1 (en) | 2001-01-18 | 2002-02-26 | California Pacific Medical Center | Camptothecin derivatives |
US6403604B1 (en) | 2001-03-01 | 2002-06-11 | California Pacific Medical Center | Nitrogen-based camptothecin derivatives |
US6855720B2 (en) | 2001-03-01 | 2005-02-15 | California Pacific Medical Center | Nitrogen-based camptothecin derivatives |
WO2003074524A2 (en) * | 2002-03-01 | 2003-09-12 | University Of Pittsburgh | Mappicine analogs, intermediates in the synthesis of mappicine analogs and methods of synthesis of mappicine analogs |
WO2003101998A1 (en) * | 2002-06-03 | 2003-12-11 | California Pacific Medical Center | Nitrogen-based homo-camptothecin derivatives |
EP1694684B1 (en) * | 2003-12-17 | 2011-08-03 | Bionumerik Pharmaceuticals, Inc. | Process for making camptothecin derivatives |
EP1757609B1 (en) | 2004-04-09 | 2013-10-16 | Chugai Seiyaku Kabushiki Kaisha | Novel water-soluble prodrug |
ITRM20040288A1 (it) * | 2004-06-11 | 2004-09-11 | Sigma Tau Ind Farmaceuti | Uso della 7-t-butossiimminometilcamptotecina per la preparazione di un medicamento per il trattamento delle neoplasie dell'utero. |
TW200744603A (en) | 2005-08-22 | 2007-12-16 | Chugai Pharmaceutical Co Ltd | Novel anticancer concomitant drug |
FR2892418B1 (fr) * | 2005-10-24 | 2010-10-22 | Servier Lab | Nouveaux composes aminoesterifies a cycle e hydrocarbone a six chainons analogues de la camptothecine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
FR2892417B1 (fr) * | 2005-10-24 | 2010-10-22 | Servier Lab | Nouveaux composes aminoesterifies a cycle e hydrocarbone a sept chainons analogues de la camptothecine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
CN100465175C (zh) * | 2005-11-29 | 2009-03-04 | 中国人民解放军第二军医大学 | 7-位取代高喜树碱类化合物及作为药物的用途 |
CN100441580C (zh) * | 2006-07-14 | 2008-12-10 | 中山大学 | 喹啉二酮衍生物及其在制备抗菌药物中的应用 |
CN102746314B (zh) * | 2011-04-18 | 2016-07-06 | 华东师范大学 | 含有稳定7元内酯环的喜树碱类化合物、制备方法和用途 |
CN117164601A (zh) * | 2022-06-02 | 2023-12-05 | 华东师范大学 | 一种高喜树碱类小分子及其应用 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5391745A (en) * | 1992-07-23 | 1995-02-21 | Sloan-Kettering Institute For Cancer Research | Methods of preparation of camptothecin analogs |
AU716377B2 (en) * | 1995-06-21 | 2000-02-24 | Ipsen Pharma S.A.S. | New analogues of camptothecin, preparation processes, their use as medicaments and the pharmaceutical compositions containing them |
-
1997
- 1997-05-12 UA UA99063448A patent/UA57757C2/uk unknown
- 1997-12-05 HU HU0001385A patent/HUP0001385A3/hu unknown
- 1997-12-05 JP JP52844798A patent/JP3576174B2/ja not_active Expired - Fee Related
- 1997-12-05 IL IL12989297A patent/IL129892A0/xx active IP Right Grant
- 1997-12-05 KR KR10-1999-7005604A patent/KR100516873B1/ko not_active IP Right Cessation
- 1997-12-05 EP EP97950235A patent/EP0946566B1/fr not_active Expired - Lifetime
- 1997-12-05 DE DE69726007T patent/DE69726007T2/de not_active Expired - Lifetime
- 1997-12-05 CA CA2275345A patent/CA2275345C/fr not_active Expired - Fee Related
- 1997-12-05 ES ES97950235T patent/ES2206760T3/es not_active Expired - Lifetime
- 1997-12-05 AT AT97950235T patent/ATE253582T1/de active
- 1997-12-05 PT PT97950235T patent/PT946566E/pt unknown
- 1997-12-05 NZ NZ335938A patent/NZ335938A/xx not_active IP Right Cessation
- 1997-12-05 AU AU53264/98A patent/AU734512B2/en not_active Ceased
- 1997-12-05 BR BRPI9713977-7A patent/BR9713977B1/pt not_active IP Right Cessation
- 1997-12-05 DK DK97950235T patent/DK0946566T3/da active
- 1997-12-05 CZ CZ0209299A patent/CZ299794B6/cs not_active IP Right Cessation
- 1997-12-05 CN CN97180816A patent/CN1090634C/zh not_active Expired - Fee Related
- 1997-12-05 WO PCT/FR1997/002217 patent/WO1998028304A1/fr active IP Right Grant
- 1997-12-05 PL PL97334092A patent/PL188109B1/pl not_active IP Right Cessation
- 1997-12-19 TW TW086119342A patent/TW410224B/zh not_active IP Right Cessation
- 1997-12-19 AR ARP970106042A patent/AR005849A1/es active IP Right Grant
- 1997-12-20 MY MYPI97006216A patent/MY122042A/en unknown
-
1999
- 1999-05-11 IL IL129892A patent/IL129892A/en not_active IP Right Cessation
- 1999-06-18 NO NO19992997A patent/NO324973B1/no not_active IP Right Cessation
-
2000
- 2000-07-04 HK HK00104033A patent/HK1024694A1/xx not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB | Patent renewed |