IL126477A - Controlled Release Drugs Containing Amylose and Hydroxypropylmethylcellulose Based Substance - Google Patents

Controlled Release Drugs Containing Amylose and Hydroxypropylmethylcellulose Based Substance

Info

Publication number
IL126477A
IL126477A IL12647797A IL12647797A IL126477A IL 126477 A IL126477 A IL 126477A IL 12647797 A IL12647797 A IL 12647797A IL 12647797 A IL12647797 A IL 12647797A IL 126477 A IL126477 A IL 126477A
Authority
IL
Israel
Prior art keywords
hpmc
tablet
carrier
cross
amylose
Prior art date
Application number
IL12647797A
Other languages
English (en)
Hebrew (he)
Other versions
IL126477A0 (en
Inventor
Francois Chouinard
Wilfrid Jacques
Original Assignee
Labopharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Labopharm Inc filed Critical Labopharm Inc
Publication of IL126477A0 publication Critical patent/IL126477A0/xx
Publication of IL126477A publication Critical patent/IL126477A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL12647797A 1996-04-10 1997-04-04 Controlled Release Drugs Containing Amylose and Hydroxypropylmethylcellulose Based Substance IL126477A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CA002173818A CA2173818A1 (fr) 1996-04-10 1996-04-10 Comprime pharmaceutique a liberation controlee contenant un support a base d'amylose reticule et d'hydroxypropylmethylcellulose
PCT/CA1997/000229 WO1997037639A1 (fr) 1996-04-10 1997-04-04 Comprime pharmaceutique a liberation controlee contenant un support a base d'amylose reticule et d'hydroxypropylmethylcellulose

Publications (2)

Publication Number Publication Date
IL126477A0 IL126477A0 (en) 1999-08-17
IL126477A true IL126477A (en) 2001-10-31

Family

ID=4157953

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12647797A IL126477A (en) 1996-04-10 1997-04-04 Controlled Release Drugs Containing Amylose and Hydroxypropylmethylcellulose Based Substance

Country Status (22)

Country Link
US (1) US5885615A (tr)
EP (1) EP0954290B1 (tr)
JP (1) JP4166278B2 (tr)
KR (1) KR100439614B1 (tr)
CN (1) CN1218396A (tr)
AT (1) ATE240719T1 (tr)
AU (1) AU711089B2 (tr)
BR (1) BR9708772A (tr)
CA (1) CA2173818A1 (tr)
CZ (1) CZ294342B6 (tr)
DE (1) DE69722247T2 (tr)
DK (1) DK0954290T3 (tr)
ES (1) ES2200166T3 (tr)
IL (1) IL126477A (tr)
MY (1) MY115535A (tr)
NO (1) NO321862B1 (tr)
NZ (1) NZ332576A (tr)
PL (1) PL187764B1 (tr)
PT (1) PT954290E (tr)
TR (1) TR199802034T2 (tr)
WO (1) WO1997037639A1 (tr)
ZA (1) ZA973054B (tr)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL109460A (en) 1993-05-10 1998-03-10 Euro Celtique Sa Controlled release formulation comprising tramadol
US6197339B1 (en) * 1997-09-30 2001-03-06 Pharmacia & Upjohn Company Sustained release tablet formulation to treat Parkinson's disease
US6284273B1 (en) * 1998-02-24 2001-09-04 Vincent Lenaerts Cross-linked high amylose starch resistant to amylase as a matrix for the slow release of biologically active compounds
WO2000033818A1 (en) 1998-12-11 2000-06-15 Nostrum Pharmaceuticals, Inc. Sustained release tablet containing hydrocolloid and cellulose ether
US6555139B2 (en) 1999-06-28 2003-04-29 Wockhardt Europe Limited Preparation of micron-size pharmaceutical particles by microfluidization
EP1174127A1 (en) * 2000-07-21 2002-01-23 Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno Composition for targeted release of an actvie substance and process for producing such a composition
WO2003017981A1 (en) * 2001-08-29 2003-03-06 Ranbaxy Laboratories Limited Controlled release formulation of clarithromycin or tinidazol
AU2003225837B2 (en) * 2002-03-15 2008-11-06 Forest Laboratories Holdings Limited NE and 5-HT reuptake inhibitors for treating visceral pain syndromes
TWI319713B (en) * 2002-10-25 2010-01-21 Sustained-release tramadol formulations with 24-hour efficacy
US20040132826A1 (en) * 2002-10-25 2004-07-08 Collegium Pharmaceutical, Inc. Modified release compositions of milnacipran
MY142195A (en) * 2002-10-25 2010-10-15 Labopharm Inc Controlled-release compositions
US20060003004A1 (en) * 2002-10-25 2006-01-05 Collegium Pharmaceutical, Inc. Pulsatile release compositions of milnacipran
US8487002B2 (en) * 2002-10-25 2013-07-16 Paladin Labs Inc. Controlled-release compositions
ATE400819T1 (de) * 2002-10-25 2008-07-15 Labopharm Inc Zubereitungen mit kontrollierter freisetzung
JP4916113B2 (ja) * 2002-11-25 2012-04-11 ボストン サイエンティフィック リミテッド 注入装置
JP2006515008A (ja) * 2003-01-28 2006-05-18 コレギウム ファーマシューティカル， インコーポレイテッド 経口投与のためのミルナシプランの多粒子状組成物
US20060172006A1 (en) * 2003-10-10 2006-08-03 Vincent Lenaerts Sustained-release tramadol formulations with 24-hour clinical efficacy
AR051654A1 (es) * 2004-11-04 2007-01-31 Astrazeneca Ab Nuevas formulaciones de pellets de liberacion modificada para inhibidores de la bomba de protones
CA2491665A1 (fr) * 2004-12-24 2006-06-24 Louis Cartilier Formulation de comprime pour liberation soutenue de principe actif
JP5269595B2 (ja) * 2005-09-09 2013-08-21 アンジェリーニ ラボファーム リミテッド ライアビリティ カンパニー １日１回投与用トラゾドン組成物
US20070071792A1 (en) * 2005-09-21 2007-03-29 Varner Signe E In VIVO formed matrices including natural biodegradale polysaccharides and ophthalmic uses thereof
WO2007040557A1 (en) * 2005-09-21 2007-04-12 Surmodics, Inc. Coatings and articles including natural biodegradable polysaccharides
EP1946780B1 (en) * 2005-11-11 2012-01-11 Asahi Kasei Chemicals Corporation Controlled release solid preparation
US20080154241A1 (en) * 2006-12-07 2008-06-26 Burkstrand Michael J Latent stabilization of bioactive agents releasable from implantable medical articles
CA2723192A1 (en) 2008-05-07 2009-11-12 Surmodics, Inc. Delivery of nucleic acid complexes from particles
PT2323633E (pt) * 2008-09-04 2012-05-29 Bristol Myers Squibb Co Composição farmacêutica estável para a administração optimizada de um inibidor de união de hiv
JP5713911B2 (ja) * 2008-10-27 2015-05-07 アルザ・コーポレーシヨン 長期放出型経口アセトアミノフェン／トラマドール投与形態
US20100260842A1 (en) * 2009-04-06 2010-10-14 Rashmi Nair Pseudoephedrine pharmaceutical formulations
US8901092B2 (en) 2010-12-29 2014-12-02 Surmodics, Inc. Functionalized polysaccharides for active agent delivery

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3065143A (en) * 1960-04-19 1962-11-20 Richardson Merrell Inc Sustained release tablet
US4167558A (en) * 1976-02-13 1979-09-11 Hoffmann-La Roche Inc. Novel sustained release tablet formulations
US4389393A (en) * 1982-03-26 1983-06-21 Forest Laboratories, Inc. Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose
US4610870A (en) * 1984-10-05 1986-09-09 E. R. Squibb & Sons, Inc. Controlled release formulation
US4734285A (en) * 1985-10-28 1988-03-29 The Dow Chemical Company Sustained release compositions
US4704285A (en) * 1985-11-18 1987-11-03 The Dow Chemical Company Sustained release compositions comprising hydroxypropyl cellulose ethers
US4855143A (en) * 1986-04-04 1989-08-08 Hans Lowey Method of preparing controlled long-acting pharmaceutical formulations in unit dosage form having uniform and comparable bioavailability characteristics
US4775535A (en) * 1986-04-04 1988-10-04 Hans Lowey Method of preparing controlled long-acting pharmaceutical formulations in unit dosage form having uniform and comparable bioavailability characteristics
US5603956A (en) * 1990-11-27 1997-02-18 Labopharm Inc. Cross-linked enzymatically controlled drug release
CA2041774C (en) * 1990-11-27 1994-04-19 Mircea A. Mateescu Use of cross-linked amylose as a matrix for the slow release of biologically active compounds
NL9201196A (nl) * 1992-07-03 1994-02-01 Tno Preparaat voor de gereguleerde afgifte van een werkzame stof en werkwijze ter bereiding van een dergelijk preparaat.
KR100304997B1 (ko) * 1992-07-24 2002-04-24 드니랑글로아 효소에의해제어되는약물방출을위한가교결합된폴리하이드록실물질을포함하는정제
US5616343A (en) * 1993-03-25 1997-04-01 Labopharm, Inc. Cross-linked amylose as a binder/disintegrant in tablets
IT1282650B1 (it) * 1996-02-19 1998-03-31 Jagotec Ag Compressa farmaceutica,caratterizzata da elevato aumento di volume a contatto con liquidi biologici

Also Published As

Publication number Publication date
NO984703L (no) 1998-12-08
US5885615A (en) 1999-03-23
NZ332576A (en) 2000-03-27
DE69722247D1 (de) 2003-06-26
ZA973054B (en) 1998-06-01
CA2173818A1 (fr) 1997-10-11
CZ294342B6 (cs) 2004-12-15
KR20000005337A (ko) 2000-01-25
BR9708772A (pt) 2000-01-04
CN1218396A (zh) 1999-06-02
DE69722247T2 (de) 2004-04-01
PL187764B1 (pl) 2004-10-29
ES2200166T3 (es) 2004-03-01
CZ325498A3 (cs) 1999-03-17
NO984703D0 (no) 1998-10-08
PL329285A1 (en) 1999-03-15
DK0954290T3 (da) 2003-09-22
IL126477A0 (en) 1999-08-17
EP0954290B1 (fr) 2003-05-21
PT954290E (pt) 2003-10-31
WO1997037639A1 (fr) 1997-10-16
EP0954290A1 (fr) 1999-11-10
NO321862B1 (no) 2006-07-17
AU711089B2 (en) 1999-10-07
MY115535A (en) 2003-07-31
JP4166278B2 (ja) 2008-10-15
JP2000507561A (ja) 2000-06-20
KR100439614B1 (ko) 2004-10-14
ATE240719T1 (de) 2003-06-15
AU2283297A (en) 1997-10-29
TR199802034T2 (tr) 1999-02-22

Similar Documents

Publication Publication Date Title
AU711089B2 (en) Pharmaceutical controlled release tablets containing a carrier based on cross-linked amylose and hydroxypropylmethylcellulose
AU608208B2 (en) Therapeutic agents
US4610870A (en) Controlled release formulation
US4756911A (en) Controlled release formulation
US4666705A (en) Controlled release formulation
CA1188614A (en) Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose
RU2138253C1 (ru) Лекарственное средство с замедленным высвобождением активнодействующего вещества
US6743445B2 (en) Low temperature coatings
AU741361B2 (en) Modified release matrix formulation of cefaclor and cephalexin
JP2004534031A (ja) 心臓および循環器疾患の治療および予防を目的とする一日一回の治療のための経口制御放出医薬組成物
EP1390015A1 (en) Taste-masking of highly water-soluble drugs
MXPA06013181A (es) Tabletas que exhiben reducida variabilidad de liberacion del farmaco.
US20010001658A1 (en) Granule modulating hydrogel system
US6150410A (en) pH independent extended release pharmaceutical formulation
JP3647859B2 (ja) 酵素的に制御された薬剤放出のための架橋されたポリヒドロキシ材料
EP1146864B1 (en) Ph independent extended release pharmaceutical formulation
US4940580A (en) Sustained release labetalol tablets
AU709413B2 (en) Sustained-release drug delivery employing a powdered hydrocolloid gum obtainable from higher plants
MXPA98008340A (en) Spraying module that has a protective element and a recolec element
EP1652522A1 (en) Sustained release tablet for oral use
US20040228918A1 (en) Granule modulating hydrogel system
IL179194A (en) Pharmaceutical tablet and a process for preparing slow release formulation thereof
AU2002305737A1 (en) Taste-masking of highly water-soluble drugs

Legal Events

Date Code Title Description
KB Patent renewed
KB Patent renewed
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees