IL126339A - Taxol derivatives - Google Patents

Taxol derivatives

Info

Publication number
IL126339A
IL126339A IL12633993A IL12633993A IL126339A IL 126339 A IL126339 A IL 126339A IL 12633993 A IL12633993 A IL 12633993A IL 12633993 A IL12633993 A IL 12633993A IL 126339 A IL126339 A IL 126339A
Authority
IL
Israel
Prior art keywords
taxol derivatives
taxol
derivatives
compounds
chain
Prior art date
Application number
IL12633993A
Other languages
English (en)
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of IL126339A publication Critical patent/IL126339A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
IL12633993A 1992-04-17 1993-04-16 Taxol derivatives IL126339A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US87050992A 1992-04-17 1992-04-17
US91472092A 1992-07-16 1992-07-16
IL10542193A IL105421A (en) 1992-04-17 1993-04-16 History of texting and the process of preparing them

Publications (1)

Publication Number Publication Date
IL126339A true IL126339A (en) 2001-03-19

Family

ID=27128160

Family Applications (3)

Application Number Title Priority Date Filing Date
IL12633993A IL126339A (en) 1992-04-17 1993-04-16 Taxol derivatives
IL10542193A IL105421A (en) 1992-04-17 1993-04-16 History of texting and the process of preparing them
IL12633998A IL126339A0 (en) 1992-04-17 1998-09-24 Taxol derivatives

Family Applications After (2)

Application Number Title Priority Date Filing Date
IL10542193A IL105421A (en) 1992-04-17 1993-04-16 History of texting and the process of preparing them
IL12633998A IL126339A0 (en) 1992-04-17 1998-09-24 Taxol derivatives

Country Status (15)

Country Link
US (3) US5352806A (de)
EP (1) EP0639186B1 (de)
JP (1) JPH07505887A (de)
KR (1) KR100263496B1 (de)
AT (1) ATE181551T1 (de)
AU (1) AU672006B2 (de)
CA (1) CA2130578A1 (de)
DE (1) DE69325454T2 (de)
DK (1) DK0639186T3 (de)
ES (1) ES2134847T3 (de)
GR (1) GR3031126T3 (de)
IL (3) IL126339A (de)
MX (1) MX9302214A (de)
PH (1) PH31610A (de)
WO (1) WO1993021173A1 (de)

Families Citing this family (115)

* Cited by examiner, † Cited by third party
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US6018073A (en) * 1991-09-23 2000-01-25 Florida State University Tricyclic taxanes having an alkoxy, alkenoxy or aryloxy substituted side-chain and pharmaceutical compositions containing them
US5721268A (en) * 1991-09-23 1998-02-24 Florida State University C7 taxane derivatives and pharmaceutical compositions containing them
US5990325A (en) 1993-03-05 1999-11-23 Florida State University Process for the preparation of 9-desoxotaxol, 9-desoxobaccatin III and analogs thereof
US6794523B2 (en) 1991-09-23 2004-09-21 Florida State University Taxanes having t-butoxycarbonyl substituted side-chains and pharmaceutical compositions containing them
US5714513A (en) * 1991-09-23 1998-02-03 Florida State University C10 taxane derivatives and pharmaceutical compositions
US6011056A (en) 1991-09-23 2000-01-04 Florida State University C9 taxane derivatives and pharmaceutical compositions containing them
US5710287A (en) 1991-09-23 1998-01-20 Florida State University Taxanes having an amino substituted side-chain and pharmaceutical compositions containing them
US5399726A (en) * 1993-01-29 1995-03-21 Florida State University Process for the preparation of baccatin III analogs bearing new C2 and C4 functional groups
US5440056A (en) * 1992-04-17 1995-08-08 Abbott Laboratories 9-deoxotaxane compounds
GB9213077D0 (en) * 1992-06-19 1992-08-05 Erba Carlo Spa Polymerbound taxol derivatives
FR2702212B1 (fr) * 1993-03-02 1995-04-07 Rhone Poulenc Rorer Sa Nouveaux taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.
US6710191B2 (en) * 1993-03-05 2004-03-23 Florida State University 9β-hydroxytetracyclic taxanes
EP0687260B1 (de) * 1993-03-05 2003-02-19 Florida State University Verfahren zur Herstellung von 9-Desoxotaxanen
US5703247A (en) * 1993-03-11 1997-12-30 Virginia Tech Intellectual Properties, Inc. 2-Debenzoyl-2-acyl taxol derivatives and methods for making same
WO1994021651A1 (en) * 1993-03-22 1994-09-29 Florida State University Taxanes having furyl or thienyl substituted side-chain
US5468769A (en) * 1993-07-15 1995-11-21 Abbott Laboratories Paclitaxel derivatives
US6005120A (en) 1993-07-20 1999-12-21 Florida State University Tricyclic and tetracyclic taxanes
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US5677470A (en) * 1994-06-28 1997-10-14 Tanabe Seiyaku Co., Ltd. Baccatin derivatives and processes for preparing the same
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US5763477A (en) * 1994-07-22 1998-06-09 Dr. Reddy's Research Foundation Taxane derivatives from 14-β-hydroxy-10 deacetylbaccatin III
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Family Cites Families (12)

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Publication number Priority date Publication date Assignee Title
FR2601676B1 (fr) * 1986-07-17 1988-09-23 Rhone Poulenc Sante Procede de preparation du taxol et du desacetyl-10 taxol
FR2601675B1 (fr) * 1986-07-17 1988-09-23 Rhone Poulenc Sante Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent
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FR2629818B1 (fr) * 1988-04-06 1990-11-16 Centre Nat Rech Scient Procede de preparation du taxol
FR2629819B1 (fr) * 1988-04-06 1990-11-16 Rhone Poulenc Sante Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii
US5175315A (en) * 1989-05-31 1992-12-29 Florida State University Method for preparation of taxol using β-lactam
IL95436A (en) * 1989-08-23 1996-07-23 Centre Nat Rech Scient Process for preparing the history of phenylisosarine
US5015744A (en) * 1989-11-14 1991-05-14 Florida State University Method for preparation of taxol using an oxazinone
FR2658510B1 (fr) * 1990-02-21 1992-04-30 Rhone Poulenc Sante Nouveau derive de la beta-phenylisoserine, sa preparation et son emploi.
FR2658513B1 (fr) * 1990-02-21 1994-02-04 Rhone Poulenc Sante Procede de preparation de l'acide cis-beta-phenylglycidique-(2r,3r).
US5200534A (en) * 1992-03-13 1993-04-06 University Of Florida Process for the preparation of taxol and 10-deacetyltaxol
FR2711370B1 (fr) * 1993-10-18 1996-01-05 Rhone Poulenc Rorer Sa Nouveaux taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.

Also Published As

Publication number Publication date
DE69325454T2 (de) 2000-01-20
KR100263496B1 (ko) 2002-01-09
EP0639186A1 (de) 1995-02-22
MX9302214A (es) 1993-10-01
EP0639186B1 (de) 1999-06-23
US5352806A (en) 1994-10-04
ATE181551T1 (de) 1999-07-15
DK0639186T3 (da) 1999-12-13
DE69325454D1 (de) 1999-07-29
ES2134847T3 (es) 1999-10-16
EP0639186A4 (de) 1995-01-10
US5530020A (en) 1996-06-25
CA2130578A1 (en) 1993-10-28
IL105421A (en) 1999-09-22
US5594157A (en) 1997-01-14
GR3031126T3 (en) 1999-12-31
AU672006B2 (en) 1996-09-19
IL105421A0 (en) 1993-08-18
PH31610A (en) 1998-11-03
IL126339A0 (en) 1999-05-09
WO1993021173A1 (en) 1993-10-28
JPH07505887A (ja) 1995-06-29
KR950700894A (ko) 1995-02-20
AU4286393A (en) 1993-11-18

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