DK0639186T3 - Taxolderivater - Google Patents

Taxolderivater

Info

Publication number
DK0639186T3
DK0639186T3 DK93912249T DK93912249T DK0639186T3 DK 0639186 T3 DK0639186 T3 DK 0639186T3 DK 93912249 T DK93912249 T DK 93912249T DK 93912249 T DK93912249 T DK 93912249T DK 0639186 T3 DK0639186 T3 DK 0639186T3
Authority
DK
Denmark
Prior art keywords
taxol derivatives
taxol
derivatives
compounds
chain
Prior art date
Application number
DK93912249T
Other languages
English (en)
Inventor
Geewananda P Gunawardana
Larry L Klein
James B Mcalpine
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of DK0639186T3 publication Critical patent/DK0639186T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
DK93912249T 1992-04-17 1993-04-14 Taxolderivater DK0639186T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US87050992A 1992-04-17 1992-04-17
US91472092A 1992-07-16 1992-07-16
PCT/US1993/003532 WO1993021173A1 (en) 1992-04-17 1993-04-14 Taxol derivatives

Publications (1)

Publication Number Publication Date
DK0639186T3 true DK0639186T3 (da) 1999-12-13

Family

ID=27128160

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93912249T DK0639186T3 (da) 1992-04-17 1993-04-14 Taxolderivater

Country Status (15)

Country Link
US (3) US5352806A (da)
EP (1) EP0639186B1 (da)
JP (1) JPH07505887A (da)
KR (1) KR100263496B1 (da)
AT (1) ATE181551T1 (da)
AU (1) AU672006B2 (da)
CA (1) CA2130578A1 (da)
DE (1) DE69325454T2 (da)
DK (1) DK0639186T3 (da)
ES (1) ES2134847T3 (da)
GR (1) GR3031126T3 (da)
IL (3) IL126339A (da)
MX (1) MX9302214A (da)
PH (1) PH31610A (da)
WO (1) WO1993021173A1 (da)

Families Citing this family (114)

* Cited by examiner, † Cited by third party
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US6794523B2 (en) 1991-09-23 2004-09-21 Florida State University Taxanes having t-butoxycarbonyl substituted side-chains and pharmaceutical compositions containing them
US6018073A (en) * 1991-09-23 2000-01-25 Florida State University Tricyclic taxanes having an alkoxy, alkenoxy or aryloxy substituted side-chain and pharmaceutical compositions containing them
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US5990325A (en) * 1993-03-05 1999-11-23 Florida State University Process for the preparation of 9-desoxotaxol, 9-desoxobaccatin III and analogs thereof
US5714513A (en) * 1991-09-23 1998-02-03 Florida State University C10 taxane derivatives and pharmaceutical compositions
US5721268A (en) 1991-09-23 1998-02-24 Florida State University C7 taxane derivatives and pharmaceutical compositions containing them
US5440056A (en) * 1992-04-17 1995-08-08 Abbott Laboratories 9-deoxotaxane compounds
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AU689770B2 (en) * 1993-03-05 1998-04-09 Florida State University Process for the preparation of 9-desoxotaxanes
US6710191B2 (en) * 1993-03-05 2004-03-23 Florida State University 9β-hydroxytetracyclic taxanes
US5703247A (en) * 1993-03-11 1997-12-30 Virginia Tech Intellectual Properties, Inc. 2-Debenzoyl-2-acyl taxol derivatives and methods for making same
DE69433355T2 (de) * 1993-03-22 2004-05-27 Florida State University, Tallahassee Taxane ohne die c-9 oxo gruppe und diese enthaltende pharmazeutische präparate
US5468769A (en) * 1993-07-15 1995-11-21 Abbott Laboratories Paclitaxel derivatives
US6005120A (en) 1993-07-20 1999-12-21 Florida State University Tricyclic and tetracyclic taxanes
FR2711370B1 (fr) * 1993-10-18 1996-01-05 Rhone Poulenc Rorer Sa Nouveaux taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.
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US5965566A (en) * 1993-10-20 1999-10-12 Enzon, Inc. High molecular weight polymer-based prodrugs
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US5677470A (en) * 1994-06-28 1997-10-14 Tanabe Seiyaku Co., Ltd. Baccatin derivatives and processes for preparing the same
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Family Cites Families (12)

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Publication number Priority date Publication date Assignee Title
FR2601675B1 (fr) * 1986-07-17 1988-09-23 Rhone Poulenc Sante Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2601676B1 (fr) * 1986-07-17 1988-09-23 Rhone Poulenc Sante Procede de preparation du taxol et du desacetyl-10 taxol
US4876399A (en) * 1987-11-02 1989-10-24 Research Corporation Technologies, Inc. Taxols, their preparation and intermediates thereof
FR2629819B1 (fr) * 1988-04-06 1990-11-16 Rhone Poulenc Sante Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii
FR2629818B1 (fr) * 1988-04-06 1990-11-16 Centre Nat Rech Scient Procede de preparation du taxol
US5175315A (en) * 1989-05-31 1992-12-29 Florida State University Method for preparation of taxol using β-lactam
CA2023645C (fr) * 1989-08-23 2002-03-26 Jean-Noel Denis Procede pour la preparation enantioselective de derives de la phenylisoserine
US5015744A (en) * 1989-11-14 1991-05-14 Florida State University Method for preparation of taxol using an oxazinone
FR2658513B1 (fr) * 1990-02-21 1994-02-04 Rhone Poulenc Sante Procede de preparation de l'acide cis-beta-phenylglycidique-(2r,3r).
FR2658510B1 (fr) * 1990-02-21 1992-04-30 Rhone Poulenc Sante Nouveau derive de la beta-phenylisoserine, sa preparation et son emploi.
US5200534A (en) * 1992-03-13 1993-04-06 University Of Florida Process for the preparation of taxol and 10-deacetyltaxol
FR2711370B1 (fr) * 1993-10-18 1996-01-05 Rhone Poulenc Rorer Sa Nouveaux taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.

Also Published As

Publication number Publication date
US5352806A (en) 1994-10-04
US5594157A (en) 1997-01-14
KR100263496B1 (ko) 2002-01-09
EP0639186A1 (en) 1995-02-22
KR950700894A (ko) 1995-02-20
JPH07505887A (ja) 1995-06-29
EP0639186A4 (en) 1995-01-10
IL126339A (en) 2001-03-19
GR3031126T3 (en) 1999-12-31
AU4286393A (en) 1993-11-18
AU672006B2 (en) 1996-09-19
ES2134847T3 (es) 1999-10-16
MX9302214A (es) 1993-10-01
US5530020A (en) 1996-06-25
DE69325454T2 (de) 2000-01-20
ATE181551T1 (de) 1999-07-15
EP0639186B1 (en) 1999-06-23
CA2130578A1 (en) 1993-10-28
IL105421A (en) 1999-09-22
WO1993021173A1 (en) 1993-10-28
IL105421A0 (en) 1993-08-18
PH31610A (en) 1998-11-03
DE69325454D1 (de) 1999-07-29
IL126339A0 (en) 1999-05-09

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