IL123553A0 - Cell-cycle checkpoint genes - Google Patents

Cell-cycle checkpoint genes

Info

Publication number
IL123553A0
IL123553A0 IL12355396A IL12355396A IL123553A0 IL 123553 A0 IL123553 A0 IL 123553A0 IL 12355396 A IL12355396 A IL 12355396A IL 12355396 A IL12355396 A IL 12355396A IL 123553 A0 IL123553 A0 IL 123553A0
Authority
IL
Israel
Prior art keywords
cell
cycle checkpoint
checkpoint genes
genes
cycle
Prior art date
Application number
IL12355396A
Other languages
English (en)
Original Assignee
Icos Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Icos Corp filed Critical Icos Corp
Publication of IL123553A0 publication Critical patent/IL123553A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
IL12355396A 1995-09-06 1996-09-06 Cell-cycle checkpoint genes IL123553A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9518220.0A GB9518220D0 (en) 1995-09-06 1995-09-06 Checkpoint gene
CZ1998656A CZ292808B6 (cs) 1995-09-06 1996-09-06 ATR polypeptid, polynukleotid, který jej kóduje, způsoby jejich detekce, vektor a protilátka
PCT/GB1996/002197 WO1997009433A1 (en) 1995-09-06 1996-09-06 Cell-cycle checkpoint genes

Publications (1)

Publication Number Publication Date
IL123553A0 true IL123553A0 (en) 1998-10-30

Family

ID=25746866

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12355396A IL123553A0 (en) 1995-09-06 1996-09-06 Cell-cycle checkpoint genes

Country Status (13)

Country Link
EP (1) EP0856058B1 (ja)
JP (1) JPH11511984A (ja)
CN (1) CN1201492A (ja)
AU (1) AU730220B2 (ja)
BR (1) BR9610168A (ja)
CA (1) CA2231190A1 (ja)
CZ (1) CZ292808B6 (ja)
GB (1) GB9518220D0 (ja)
IL (1) IL123553A0 (ja)
NO (1) NO980957L (ja)
PL (1) PL325427A1 (ja)
SK (1) SK30298A3 (ja)
WO (1) WO1997009433A1 (ja)

Families Citing this family (94)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1461197A (en) * 1995-11-16 1997-06-05 Icos Corporation Cell cycle checkpoint pik-related kinase materials and methods
GB9718952D0 (en) * 1997-09-05 1997-11-12 Medical Res Council Mammalian chk1 effector cell cycle checkpoint protein kinase materials and methods
EP1060251B1 (en) 1998-02-23 2006-06-28 ICOS Corporation Phosphodiesterase 10
US6479256B1 (en) 1998-03-04 2002-11-12 Icos Corporation Lectomedin materials and methods
US6071691A (en) * 1998-04-27 2000-06-06 Oregon Health Science University Materials and methods for modulating differentiation
EP2281835B1 (en) 1999-04-09 2013-11-06 Zoetis P&U LLC Attenuated Pasteurellaceae bacterium having a mutation in a virulence gene
US6790950B2 (en) 1999-04-09 2004-09-14 Pharmacia & Upjohn Company Anti-bacterial vaccine compositions
US6670167B1 (en) * 1999-11-01 2003-12-30 Agouron Pharmaceuticals, Inc. Catalytic domain of the human effector cell cycle checkpoint protein kinase materials and methods for identification of inhibitors thereof
US6344549B1 (en) 1999-10-14 2002-02-05 Icos Corporation ATR-2 cell cycle checkpoint
EP1222273A2 (en) 1999-10-22 2002-07-17 PHARMACIA & UPJOHN COMPANY Drosophila g protein coupled receptors, nucleic acids, and methods related to the same
WO2001038533A2 (en) 1999-11-24 2001-05-31 Pharmacia & Upjohn Company G protein-coupled receptor-like receptors and modulators thereof
US6498026B2 (en) 2000-02-25 2002-12-24 Hercules Incorporated Variant galactose oxidase, nucleic acid encoding same, and methods of using same
US6734005B2 (en) 2000-05-22 2004-05-11 Pharmacia & Upjohn Company Matrix metalloproteinases
US6686449B2 (en) 2000-06-30 2004-02-03 Pharmacia & Upjohn Company Mutant presenilin 1 polypeptides
WO2002002639A2 (en) 2000-07-05 2002-01-10 Pharmacia & Upjohn Company Human ion channels
US7754208B2 (en) 2001-01-17 2010-07-13 Trubion Pharmaceuticals, Inc. Binding domain-immunoglobulin fusion proteins
US7098007B2 (en) 2001-08-22 2006-08-29 California Institute Of Technology Cloning and functional assays of Xenopus ATR
AU2003219753A1 (en) * 2002-02-13 2003-09-04 University Of Rochester Methods of inhibiting hiv-1 vpr activity and hiv-1 infectivity using atr or rad17 inhibitors
WO2004045532A2 (en) 2002-11-15 2004-06-03 Chiron Corporation Methods for preventing and treating cancer metastasis and bone loss associated with cancer metastasis
WO2004070062A2 (en) * 2003-02-04 2004-08-19 Wyeth Compositions and methods for diagnosing and treating cancers
US7541158B2 (en) 2004-04-14 2009-06-02 Monell Chemical Senses Center Taste receptors of the T1R family from domestic dog
US8071113B2 (en) 2004-05-24 2011-12-06 The United States Of America As Represented By The Department Of Health And Human Services Live, oral vaccine for protection against Shigella dysenteriae serotype 1
US20060134698A1 (en) 2004-12-20 2006-06-22 Evanston Northwestern Healthcare Research Institute Methods for treating cardiac disease by modifying an N-terminal domain of troponin I
US10307481B2 (en) 2005-07-25 2019-06-04 Aptevo Research And Development Llc CD37 immunotherapeutics and uses thereof
CN101534858A (zh) 2006-01-05 2009-09-16 诺华有限公司 预防和治疗癌症转移和癌症转移相关性骨丢失的方法
NZ573646A (en) 2006-06-12 2012-04-27 Wyeth Llc Single-chain multivalent binding proteins with effector function
WO2009047567A1 (en) * 2007-10-10 2009-04-16 University Of Sheffield Assay for identifying agents which inhibit the atr and/or dna-pk pathways
WO2009126944A1 (en) 2008-04-11 2009-10-15 Trubion Pharmaceuticals, Inc. Cd37 immunotherapeutic and combination with bifunctional chemotherapeutic thereof
PT2344540T (pt) 2008-10-02 2018-02-02 Aptevo Res & Development Llc Proteínas de ligação multi-alvo antagonistas de cd86
US20130052195A1 (en) 2009-12-23 2013-02-28 Emergent Product Development Seattle,LLC Compositions Comprising TNF-alpha and IL-6 Antagonists and Methods of Use Thereof
US20130089554A1 (en) 2009-12-29 2013-04-11 Emergent Product Development Seattle, Llc RON Binding Constructs and Methods of Use Thereof
RU2447899C2 (ru) 2010-05-27 2012-04-20 Михаил Валентинович Филатов Композиция для лечения гепатита с и способ лечения гепатита с
AU2013289943B2 (en) 2012-07-13 2017-06-08 Calysta Inc. Biorefinery system, methods and compositions thereof
US9909153B2 (en) 2012-11-09 2018-03-06 Calysta, Inc. Compositions and methods for biological production of fatty acid derivatives
KR102203918B1 (ko) 2013-06-18 2021-01-15 칼리스타, 인코포레이티드 락트산 탈수소효소 형질전환체를 이용하는 c1 화합물로부터 락테이트의 생물학적 생산을 위한 조성물 및 방법
CA2956667A1 (en) 2013-07-29 2015-02-05 Bluebird Bio, Inc. Multipartite signaling proteins and uses thereof
EP3090070B1 (en) 2014-01-02 2020-04-29 Trelys, Inc. Compositions and methods for biological production of amino acids in hydrogenotrophic microorganisms
CN105916976A (zh) 2014-01-16 2016-08-31 凯利斯塔公司 碳水化合物富集的重组微生物
EP3102596A2 (en) 2014-02-07 2016-12-14 Effector Therapeutics Inc. Compositions and methods for treating neurological disorders
JP2017510552A (ja) 2014-02-07 2017-04-13 イーフェクター セラピューティクス， インコーポレイテッド 線維性疾患を治療するための方法
US9364523B2 (en) 2014-03-17 2016-06-14 Tapimmune Inc. Chimeric nucleic acid molecule with non-AUG translation initiation sequences
WO2015175809A1 (en) 2014-05-15 2015-11-19 Calysta, Inc. Methods for biological production of very long carbon chain compounds
ES2841274T3 (es) 2014-08-04 2021-07-07 Hutchinson Fred Cancer Res Inmunoterapia con células T específica para WT-1
KR102357004B1 (ko) 2014-10-27 2022-01-27 프레드 헛친슨 켄서 리서치 센터 입양 세포 면역요법의 효능을 강화하기 위한 조성물 및 방법
AU2016258183A1 (en) 2015-05-06 2017-11-16 Trelys, Inc. Compositions and methods for biological production of methionine
WO2016187486A1 (en) 2015-05-19 2016-11-24 Fred Hutchinson Cancer Research Center Biomarkers and uses thereof for selecting pancreas cancer intervention
AU2016326449B2 (en) 2015-09-21 2024-10-31 Aptevo Research And Development Llc CD3 binding polypeptides
WO2017112944A1 (en) 2015-12-23 2017-06-29 Fred Hutchinson Cancer Research Center High affinity t cell receptors and uses thereof
EP3397774A1 (en) 2015-12-31 2018-11-07 Effector Therapeutics Inc. Mnk biomarkers and uses thereof
CA3010977A1 (en) 2016-01-11 2017-07-20 Zoetis Services Llc Novel cross protective vaccine compositions for porcine epidemic diarrhea virus
WO2017192924A1 (en) 2016-05-04 2017-11-09 Fred Hutchinson Cancer Research Center Cell-based neoantigen vaccines and uses thereof
WO2017193104A1 (en) 2016-05-06 2017-11-09 Fred Hutchinson Cancer Research Center T-cell immunotherapy specific for mart-1
BR112019005633A8 (pt) 2016-09-23 2023-04-11 Hutchinson Fred Cancer Res Tcrs específicos para antigênio ha-1 de histocompatibilidade (h) menor e usos dos mesmos
KR20190054094A (ko) 2016-09-27 2019-05-21 세로 테라퓨틱스, 인코포레이티드 키메라 포식작용 수용체 분자
AU2017356322B2 (en) 2016-11-14 2023-09-21 Fred Hutchinson Cancer Center High affinity merkel cell polyomavirus T antigen-specific TCRs and uses thereof
KR102602018B1 (ko) 2016-12-14 2023-11-15 조에티스 서비시즈 엘엘씨 젖떼기 전, 유럽의 돼지 생식기 및 호흡기 증후군 (prrs) 균주 바이러스에 대한 효과적인 백신접종
US11397183B2 (en) 2017-02-09 2022-07-26 Fred Hutchinson Cancer Center Biomarkers and uses thereof for selecting immunotherapy intervention
KR102375033B1 (ko) 2017-03-15 2022-03-15 프레드 헛친슨 켄서 리서치 센터 고친화도 mage-a1-특이적 tcr 및 이의 용도
US10780119B2 (en) 2017-05-24 2020-09-22 Effector Therapeutics Inc. Methods and compositions for cellular immunotherapy
CA3070272A1 (en) 2017-07-20 2019-01-24 Aptevo Research And Development Llc Antigen binding proteins binding to 5t4 and 4-1bb and related compositions and methods
WO2019055862A1 (en) 2017-09-14 2019-03-21 Fred Hutchinson Cancer Research Center HIGH AFFINITY T CELL RECEPTORS AND USES THEREOF
CN111386284B (zh) 2017-09-26 2024-08-30 森罗治疗公司 嵌合吞噬受体分子和使用方法
WO2019109047A1 (en) 2017-12-01 2019-06-06 Fred Hutchinson Cancer Research Center Binding proteins specific for 5t4 and uses thereof
RU2756100C1 (ru) 2017-12-20 2021-09-28 Харбор Байомед (Шанхай) Ко., Лтд Антитела, связывающие ctla-4, и их применение
WO2019140278A1 (en) 2018-01-11 2019-07-18 Fred Hutchinson Cancer Research Center Immunotherapy targeting core binding factor antigens
SG11202007660UA (en) 2018-02-12 2020-09-29 Hutchinson Fred Cancer Res Cyclin a1 specific t cell receptors and uses thereof
JP2021514631A (ja) 2018-02-26 2021-06-17 フレッド ハッチンソン キャンサー リサーチ センター 細胞免疫療法のための組成物および方法
EP3774906A1 (en) 2018-03-28 2021-02-17 Cero Therapeutics, Inc. Chimeric tim4 receptors and uses thereof
MX2020010235A (es) 2018-03-28 2020-10-28 Cero Therapeutics Inc Vectores de expresion para receptores de engullimiento quimerico, celulas hospederas geneticamente modificadas y usos de los mismos.
AU2019243154A1 (en) 2018-03-28 2020-10-01 Cero Therapeutics, Inc. Cellular immunotherapy compositions and uses thereof
US20210015865A1 (en) 2018-03-28 2021-01-21 Cero Therapeutics, Inc. Chimeric engulfment receptors and uses thereof for neurodegenerative diseases
US20210223248A1 (en) 2018-06-01 2021-07-22 Fred Hutchinson Cancer Research Center Biomarkers, uses thereof for selecting immunotherapy intervention, and immunotherapy methods
WO2020139974A1 (en) 2018-12-27 2020-07-02 Calysta, Inc. Glycogen-null methanotrophs and uses thereof
CN114026116A (zh) 2019-02-20 2022-02-08 弗雷德哈钦森癌症研究中心 Ras新抗原特异性结合蛋白及其用途
KR20210138043A (ko) 2019-03-11 2021-11-18 프레드 헛친슨 켄서 리서치 센터 고 결합 활성 wt1 t 세포 수용체 및 이의 용도
AU2020334064A1 (en) 2019-08-20 2022-03-03 Fred Hutchinson Cancer Center T-cell immunotherapy specific for WT-1
WO2021067875A1 (en) 2019-10-03 2021-04-08 Cero Therapeutics, Inc. Chimeric tim4 receptors and uses thereof
WO2021146328A1 (en) 2020-01-13 2021-07-22 Aptevo Research And Development Llc Formulations for protein therapeutics
MX2022008655A (es) 2020-01-13 2022-09-23 Aptevo Res & Development Llc Metodos y composiciones para prevenir la adsorcion de proteinas terapeuticas en componentes del sistema de administracion de farmacos.
US11376320B2 (en) 2020-03-05 2022-07-05 Iowa State University Research Foundation, Inc. Immunogenic and vaccine compositions against SARS-CoV-2
WO2022036287A1 (en) 2020-08-14 2022-02-17 Cero Therapeutics, Inc. Anti-cd72 chimeric receptors and uses thereof
WO2022036265A1 (en) 2020-08-14 2022-02-17 Cero Therapeutics, Inc. Chimeric tim receptors and uses thereof
WO2022036285A1 (en) 2020-08-14 2022-02-17 Cero Therapeutics, Inc. Compositions and methods for treating cancer with chimeric tim receptors in combination with inhibitors of poly (adp-ribose) polymerase
CN116724053A (zh) 2020-09-24 2023-09-08 弗雷德哈钦森癌症中心 靶向sox2抗原的免疫治疗
WO2022066973A1 (en) 2020-09-24 2022-03-31 Fred Hutchinson Cancer Research Center Immunotherapy targeting pbk or oip5 antigens
WO2022072431A1 (en) 2020-09-30 2022-04-07 Zoetis Services Llc Novel pasteurella multocida strains and vaccines having hyac and nanp deletions
TW202222841A (zh) 2020-10-06 2022-06-16 福瑞德哈金森腫瘤研究中心 用於治療表現mage-a1之疾病的組成物及方法
KR20230160242A (ko) 2021-02-26 2023-11-23 켈로니아 테라퓨틱스, 인코포레이티드 림프구 표적화된 렌티바이러스 벡터
CN115216451A (zh) 2021-04-16 2022-10-21 硕腾服务有限责任公司 伪狂犬病病毒疫苗
JP2024519964A (ja) 2021-05-21 2024-05-21 アプティーボ リサーチ アンド デベロップメント エルエルシー タンパク質治療薬のための投薬レジメン
WO2023010097A1 (en) 2021-07-28 2023-02-02 Cero Therapeutics, Inc. Chimeric tim4 receptors and uses thereof
TW202334405A (zh) 2021-12-15 2023-09-01 美商英特瑞斯生物療法公司 假型分型之病毒顆粒、包含其之組合物及其用途
CN118267462A (zh) 2022-12-29 2024-07-02 硕腾服务有限责任公司 接种猪以抗伪狂犬病病毒的方法
WO2024148328A2 (en) 2023-01-06 2024-07-11 Aptevo Research And Development Llc Bispecific pd-l1 and cd40 binding molecules and uses thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1461197A (en) * 1995-11-16 1997-06-05 Icos Corporation Cell cycle checkpoint pik-related kinase materials and methods

Also Published As

Publication number Publication date
BR9610168A (pt) 1998-08-11
AU6884696A (en) 1997-03-27
PL325427A1 (en) 1998-07-20
NO980957D0 (no) 1998-03-05
CA2231190A1 (en) 1997-03-13
CZ65698A3 (cs) 2000-01-12
EP0856058A1 (en) 1998-08-05
JPH11511984A (ja) 1999-10-19
CZ292808B6 (cs) 2003-12-17
SK30298A3 (en) 2000-04-10
NO980957L (no) 1998-05-05
WO1997009433A1 (en) 1997-03-13
AU730220B2 (en) 2001-03-01
GB9518220D0 (en) 1995-11-08
CN1201492A (zh) 1998-12-09
EP0856058B1 (en) 2006-07-26

Similar Documents

Publication Publication Date Title
IL123553A0 (en) Cell-cycle checkpoint genes
GB9502468D0 (en) DNA Sequence
GB2306848B (en) Hydrophone
DE69634130D1 (en) Elektrophotographisches toner
GB9506051D0 (en) Gene expression
GB2300210B (en) Piling
GB9514476D0 (en) Retractable step
HUP9903075A3 (en) Cell-cycle checkpoint genes cell-cycle checkpoint genes
AP9600802A0 (en) Libricant
GB9513063D0 (en) Recycle circle
GB9606873D0 (en) Pile
GB9722556D0 (en) Methods
GB9514202D0 (en) Antibody genes
GB9503605D0 (en) Novel genes
AU667P (en) NOEMI Rhododendron simsii
AU668P (en) MELODIE Rhododendron simsii
AU1052P (en) POTPURRI Rhododendron simsii
AU1081P (en) BEENAK Rhododendron simsii
GB9525962D0 (en) Gene expression
GB9615797D0 (en) Gene expression
GB9513142D0 (en) A perming aid
GB9506554D0 (en) Pile
GB9521890D0 (en) Pile
HU9500095V0 (en) Pile
AU1105P (en) DALESE Metrosideros excelsus