IL122609A0 - Meiosis regulating compounds - Google Patents

Meiosis regulating compounds

Info

Publication number
IL122609A0
IL122609A0 IL12260996A IL12260996A IL122609A0 IL 122609 A0 IL122609 A0 IL 122609A0 IL 12260996 A IL12260996 A IL 12260996A IL 12260996 A IL12260996 A IL 12260996A IL 122609 A0 IL122609 A0 IL 122609A0
Authority
IL
Israel
Prior art keywords
regulating compounds
meiosis regulating
meiosis
compounds
regulating
Prior art date
Application number
IL12260996A
Other languages
English (en)
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of IL122609A0 publication Critical patent/IL122609A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • C07J41/0016Oximes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J9/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL12260996A 1995-06-23 1996-06-21 Meiosis regulating compounds IL122609A0 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DK73095 1995-06-23
DK72895 1995-06-23
DK146195 1995-12-22
PCT/DK1996/000273 WO1997000884A1 (en) 1995-06-23 1996-06-21 Meiosis regulating compounds

Publications (1)

Publication Number Publication Date
IL122609A0 true IL122609A0 (en) 1998-08-16

Family

ID=27220892

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12260996A IL122609A0 (en) 1995-06-23 1996-06-21 Meiosis regulating compounds

Country Status (18)

Country Link
EP (1) EP0857173B1 (de)
JP (1) JPH11507929A (de)
KR (1) KR19990028366A (de)
CN (1) CN1191543A (de)
AR (1) AR003441A1 (de)
AT (1) ATE254628T1 (de)
AU (1) AU718246B2 (de)
BR (1) BR9608968A (de)
CA (1) CA2224866A1 (de)
CZ (1) CZ408097A3 (de)
DE (1) DE69630802T2 (de)
HU (1) HUP9900454A3 (de)
IL (1) IL122609A0 (de)
NO (1) NO314231B1 (de)
PL (1) PL185622B1 (de)
RU (1) RU2182909C2 (de)
TW (1) TW474943B (de)
WO (1) WO1997000884A1 (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0984980B1 (de) * 1997-05-16 2002-12-04 Akzo Nobel N.V. 20-aralkyl-5,alpha,-pregnan derivate
CN1259138A (zh) * 1997-06-04 2000-07-05 阿克佐诺贝尔公司 调节减数分裂的17β-烯丙氧基(硫代)烷基-雄甾烷衍生物
AU2160999A (en) 1997-12-18 1999-07-12 Akzo Nobel N.V. 17beta-aryl (arylmethyl) oxy(thio)alkyl -androstane derivatives
IL139241A0 (en) 1998-05-13 2001-11-25 Novo Nordisk As Meiosis regulating compounds
EP0957108A1 (de) * 1998-05-14 1999-11-17 Schering Aktiengesellschaft Ungesättigte Cholestan-derivate zur Regulierung von Meiose und pharmazeutische Präparate davon
EP1087988A1 (de) * 1998-06-19 2001-04-04 Novo Nordisk A/S Die meiose regulierende verbindungen
JP2002532511A (ja) 1998-12-11 2002-10-02 アクゾ・ノベル・エヌ・ベー 減数分裂調節活性を有する22s−ヒドロキシコレスタ−8,14−ジエン誘導体
WO2000036132A1 (en) * 1998-12-14 2000-06-22 Merck & Co., Inc. Hiv integrase inhibitors
BR0008065A (pt) * 1999-02-10 2001-11-06 Schering Aktiengellschaft Derivados de colestano insaturados e seu uso para a preparação de medicamentos que regulam meiose
EP1156822B1 (de) 1999-02-24 2006-02-08 Novo Nordisk A/S In vitro methode zur synchronisation von oozytenreifung
ATE361091T1 (de) * 1999-02-24 2007-05-15 Novo Nordisk As Behandlung von unfruchtbarkeit
ATE306942T1 (de) 1999-09-16 2005-11-15 Novo Nordisk As Zusammensetzung zur in-vitro befruchtung
EP1127890A1 (de) 2000-02-22 2001-08-29 Schering Aktiengesellschaft Steroid Derivate mit einem an Ring A des Steroidgerüstes kondensierten Ring zur Regulierung der Meiose
US20030153808A1 (en) * 2000-02-25 2003-08-14 Christa Hegele-Hartung Implantation rate using ff-mas
EP1245572A1 (de) 2001-03-26 2002-10-02 Schering Aktiengesellschaft Aminosterol-Verbindungen, ihre Verwendung zur Herstellung Meiose-regulierender Medikamenten und ein Vefahren zu ihrer Herstellung
US8399441B2 (en) 2004-10-25 2013-03-19 Virginia Commonwealth University Nuclear sulfated oxysterol, potent regulator of lipid homeostasis, for therapy of hypercholesterolemia, hypertriglycerides, fatty liver diseases, and atherosclerosis
WO2006047022A1 (en) 2004-10-25 2006-05-04 Virginia Commonwealth University Nuclear sulfated oxysterol, potent regulator of cholesterol homeostasis, for therapy of hypercholesterolemia, hyperlipidemia, and atherosclerosis
CN102258004B (zh) * 2010-05-27 2013-07-17 中国科学院动物研究所 一种体外保存/培养卵母细胞以抑制卵母细胞生发泡破裂的方法
US9034859B2 (en) 2011-04-06 2015-05-19 Virginia Commonwealth University Sulfated oxysterol and oxysterol sulfation by hydroxysterol sulfotransferase promote lipid homeostasis and liver proliferation
CN113956315B (zh) 2011-09-08 2024-08-09 萨奇治疗股份有限公司 神经活性类固醇、组合物、及其用途
EP3932932A1 (de) 2013-03-13 2022-01-05 Sage Therapeutics, Inc. Neuroaktive steroide und verfahren zur verwendung davon
TW202348234A (zh) 2013-12-24 2023-12-16 維吉尼亞聯邦大學 氧化膽固醇硫酸鹽(ocs)之用途
US10259840B2 (en) 2014-06-18 2019-04-16 Sage Therapeutics, Inc. Oxysterols and methods of use thereof
EA024619B1 (ru) * 2014-11-21 2016-10-31 Эльвин Гаджи оглы Керимли ФРАКСИНОСТЕРИН - 24β-ЭТИЛХОЛЕСТА-20-КАРБОКСИ-6(7),8(9)-ДИЕН 3β-ОЛА И ЕГО ПРОИЗВОДНОЕ
US10696712B2 (en) 2015-07-06 2020-06-30 Sage Therapeutics, Inc. Oxysterols and methods of use thereof
CA2991313C (en) 2015-07-06 2023-12-19 Sage Therapeutics, Inc. Oxysterols and methods of use thereof
AU2017240157B2 (en) 2016-04-01 2022-10-20 Sage Therapeutics, Inc. Oxysterols and methods of use thereof
US10752653B2 (en) 2016-05-06 2020-08-25 Sage Therapeutics, Inc. Oxysterols and methods of use thereof
MD3481846T2 (ro) 2016-07-07 2021-11-30 Sage Therapeutics Inc 24-Hidroxisteroli 11-substituiți pentru utilizare în tratamentul stărilor legate de NMDA
HRP20220932T1 (hr) 2016-08-02 2022-10-28 Virginia Commonwealth University Sastavi koji sadrže 5-kolesten-3, 25-diol, 3-sulfat (25hc3s) ili njegovu farmaceutski prihvatljivu sol i barem jedan ciklički oligosaharid
CA3038900A1 (en) 2016-09-30 2018-04-05 Sage Therapeutics, Inc. C7 substituted oxysterols and methods as nmda modulators
AU2017345399B2 (en) 2016-10-18 2022-02-24 Sage Therapeutics, Inc. Oxysterols and methods of use thereof
NZ752732A (en) 2016-10-18 2024-08-30 Sage Therapeutics Inc Oxysterols and methods of use thereof
CN112430251A (zh) * 2020-11-23 2021-03-02 广州瀚信通信科技股份有限公司 一种治疗白内障的化合物及其制备方法和应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5716777A (en) * 1994-06-23 1998-02-10 Novo Nordisk A/S Regulation of meiosis using sterols

Also Published As

Publication number Publication date
NO976044D0 (no) 1997-12-22
DE69630802T2 (de) 2004-08-12
AU718246B2 (en) 2000-04-13
MX9800123A (es) 1998-03-29
WO1997000884A1 (en) 1997-01-09
BR9608968A (pt) 1999-06-29
KR19990028366A (ko) 1999-04-15
EP0857173B1 (de) 2003-11-19
AR003441A1 (es) 1998-08-05
CA2224866A1 (en) 1997-01-09
PL185622B1 (pl) 2003-06-30
CN1191543A (zh) 1998-08-26
EP0857173A1 (de) 1998-08-12
CZ408097A3 (cs) 1998-06-17
JPH11507929A (ja) 1999-07-13
DE69630802D1 (de) 2003-12-24
RU2182909C2 (ru) 2002-05-27
NO976044L (no) 1998-02-20
HUP9900454A2 (hu) 1999-06-28
HUP9900454A3 (en) 1999-11-29
NO314231B1 (no) 2003-02-17
TW474943B (en) 2002-02-01
AU6122796A (en) 1997-01-22
ATE254628T1 (de) 2003-12-15
PL324219A1 (en) 1998-05-11

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