IL120590A - N-(2-hydroxy-1-phenylethyl)pyrimido¬1,2-a¾indol-10-ylmethylphenyl-acetamides their preparation and pharmaceutical compositions containing them - Google Patents

N-(2-hydroxy-1-phenylethyl)pyrimido¬1,2-a¾indol-10-ylmethylphenyl-acetamides their preparation and pharmaceutical compositions containing them

Info

Publication number
IL120590A
IL120590A IL12059097A IL12059097A IL120590A IL 120590 A IL120590 A IL 120590A IL 12059097 A IL12059097 A IL 12059097A IL 12059097 A IL12059097 A IL 12059097A IL 120590 A IL120590 A IL 120590A
Authority
IL
Israel
Prior art keywords
ylmethylphenyl
acetamides
pyrimido
phenylethyl
hydroxy
Prior art date
Application number
IL12059097A
Other languages
English (en)
Other versions
IL120590A0 (en
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Priority to IL13164597A priority Critical patent/IL131645A/xx
Publication of IL120590A0 publication Critical patent/IL120590A0/xx
Publication of IL120590A publication Critical patent/IL120590A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL12059097A 1996-04-04 1997-04-02 N-(2-hydroxy-1-phenylethyl)pyrimido¬1,2-a¾indol-10-ylmethylphenyl-acetamides their preparation and pharmaceutical compositions containing them IL120590A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IL13164597A IL131645A (en) 1996-04-04 1997-04-02 Pyrimido ¬1,2-a¾indole derivatives and their preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19613550A DE19613550A1 (de) 1996-04-04 1996-04-04 Neue Pyrimido[1,2-a]indole

Publications (2)

Publication Number Publication Date
IL120590A0 IL120590A0 (en) 1997-08-14
IL120590A true IL120590A (en) 2000-02-17

Family

ID=7790502

Family Applications (3)

Application Number Title Priority Date Filing Date
IL12059097A IL120590A (en) 1996-04-04 1997-04-02 N-(2-hydroxy-1-phenylethyl)pyrimido¬1,2-a¾indol-10-ylmethylphenyl-acetamides their preparation and pharmaceutical compositions containing them
IL13164597A IL131645A (en) 1996-04-04 1997-04-02 Pyrimido ¬1,2-a¾indole derivatives and their preparation
IL13164599A IL131645A0 (en) 1996-04-04 1999-08-30 Pyrimido ¬1,2-a¾ indole derivaties and their preparation

Family Applications After (2)

Application Number Title Priority Date Filing Date
IL13164597A IL131645A (en) 1996-04-04 1997-04-02 Pyrimido ¬1,2-a¾indole derivatives and their preparation
IL13164599A IL131645A0 (en) 1996-04-04 1999-08-30 Pyrimido ¬1,2-a¾ indole derivaties and their preparation

Country Status (33)

Country Link
US (1) US6114341A (id)
EP (1) EP0799828A3 (id)
JP (1) JPH1059972A (id)
KR (1) KR970070008A (id)
CN (2) CN1067393C (id)
AR (1) AR006497A1 (id)
AU (1) AU725786B2 (id)
BG (1) BG62934B1 (id)
BR (1) BR9701675A (id)
CA (1) CA2201434A1 (id)
CO (1) CO4520306A1 (id)
CZ (1) CZ102297A3 (id)
DE (1) DE19613550A1 (id)
DZ (1) DZ2201A1 (id)
EE (1) EE9700078A (id)
HN (1) HN1997000045A (id)
HR (1) HRP970154A2 (id)
HU (1) HUP9700708A3 (id)
ID (1) ID16520A (id)
IL (3) IL120590A (id)
MA (1) MA24131A1 (id)
MY (1) MY126362A (id)
NO (1) NO309092B1 (id)
NZ (1) NZ314497A (id)
PE (1) PE42398A1 (id)
PL (1) PL319249A1 (id)
SG (1) SG63698A1 (id)
SK (1) SK42797A3 (id)
SV (1) SV1997000025A (id)
TN (1) TNSN97061A1 (id)
TR (1) TR199700261A2 (id)
YU (1) YU12397A (id)
ZA (1) ZA972829B (id)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19826469A1 (de) * 1998-06-13 2000-05-25 Bayer Ag Verfahren zur Herstellung von 2,4-Dimethylcarbolin und 2,4-Dimethylpyrimido[1,2-a]indol
AU2001244635A1 (en) * 2000-03-30 2001-10-15 Yamanouchi Pharmaceutical Co..Ltd. Hydrazide derivatives
DE10030375A1 (de) * 2000-06-21 2002-01-03 Bayer Ag Verwendung von MTP-Inhibitoren zur Senkung von ppTRL
JP4254093B2 (ja) * 2001-10-17 2009-04-15 宇部興産株式会社 ５−ハロゲノインドールの製法
DE10349175A1 (de) * 2003-10-22 2005-05-19 Bayer Healthcare Ag Mittel zur Gewichtsreduktion
AU2005221656B2 (en) 2004-03-05 2011-06-23 The Trustees Of The University Of Pennsylvania Methods for treating disorders or diseases associated with hyperlipidemia and hypercholesterolemia while minimizing side-effects
EP1737460A2 (en) * 2004-04-09 2007-01-03 Janssen Pharmaceutica N.V. Intermittent dosing regimen for the treatment of overweight with mtp-inhibitors
MX2007013932A (es) 2005-05-12 2008-01-28 Bard Inc C R Filtro de coagulo de sangre removible.
EP1890767A2 (en) * 2005-05-27 2008-02-27 Pfizer Products Inc. Combination of a cannabinoid-1- receptor-antagonist and a microsomal triglyceride transfer protein inhibitor for treating obesity or mainataining weight loss
WO2007021340A1 (en) 2005-08-09 2007-02-22 C.R. Bard Inc Embolus blood clot filter and delivery system
WO2007047725A2 (en) * 2005-10-18 2007-04-26 Aegerion Pharmaceuticals Methods for treating disorders associated with hyperlipidemia in a mammal
US10188496B2 (en) 2006-05-02 2019-01-29 C. R. Bard, Inc. Vena cava filter formed from a sheet
AU2007338625A1 (en) * 2006-12-21 2008-07-03 Aegerion Pharmaceuticals, Inc. Methods for treating obesity with a combination comprising a MTP inhibitor and a cholesterol absorption inhibitor
CN116322682A (zh) 2020-07-29 2023-06-23 艾米琳制药有限责任公司 在治疗儿科患者的高脂血症和高胆固醇血症的方法中使用的洛美他派

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA718536B (en) * 1971-01-11 1972-09-27 Wyeth John & Brother Ltd Heterocyclic compounds
DE2200584A1 (de) * 1971-01-11 1972-07-27 Wyeth John & Brother Ltd Heterocyclische Verbindungen,Verfahren zu ihrer Herstellung und ihre Verwendung in pharmazeutischen Zubereitungen
GB8614246D0 (en) * 1986-06-11 1986-07-16 Wyeth John & Brother Ltd Substituted pyrimidoindoles
DE4112533A1 (de) * 1991-04-17 1992-10-22 Bayer Ag Verfahren zur herstellung von enantiomerenreinen substituierten (chinolin-2-yl-methoxy)phenyl-essigsaeuren
DE4200954A1 (de) * 1991-04-26 1992-10-29 Bayer Ag Heterocyclisch substituierte phenylessigsaeurederivate
DE4208052A1 (de) * 1992-03-13 1993-09-16 Bayer Ag Imidazolyl substituierte phenylessigsaeureamide
US5576342A (en) * 1992-03-13 1996-11-19 Bayer Aktiengesellschaft Phenylglycinamides of heterocyclically substitued phenylacetic acid derivatives
DE4208051A1 (de) * 1992-03-13 1993-09-16 Bayer Ag Substituierte phenylessigsaeureamide
DE4309968A1 (de) * 1993-03-26 1994-09-29 Bayer Ag Phenylglycinamide von heterocyclisch substituierten Phenylessigsäurederivaten
KR950704328A (ko) * 1992-11-05 1995-11-17 데이비드 로버츠 5-HT₄ 수용체 길항제로서의 피페리딘 유도체(Piperidine Derivatives as 5-HT₄ Receptor Antagonists)
DE4302956A1 (de) * 1993-02-03 1994-08-04 Bayer Ag Substituierte Imidazo(4,5-b)pyridine und Benzimidazole

Also Published As

Publication number Publication date
IL131645A (en) 2000-12-06
CN1312246A (zh) 2001-09-12
TNSN97061A1 (fr) 2005-03-15
SK42797A3 (en) 1997-11-05
EP0799828A2 (de) 1997-10-08
CN1176965A (zh) 1998-03-25
CO4520306A1 (es) 1997-10-15
AR006497A1 (es) 1999-08-25
ID16520A (id) 1997-10-09
US6114341A (en) 2000-09-05
CA2201434A1 (en) 1997-10-04
BR9701675A (pt) 1998-11-03
BG62934B1 (bg) 2000-11-30
MX9702445A (es) 1997-10-31
IL120590A0 (en) 1997-08-14
DE19613550A1 (de) 1997-10-09
EP0799828A3 (de) 1998-04-08
AU1660397A (en) 1997-10-09
HUP9700708A2 (hu) 1998-10-28
CN1067393C (zh) 2001-06-20
SG63698A1 (en) 1999-03-30
BG101379A (en) 1997-11-28
NO971512L (no) 1997-10-06
HU9700708D0 (en) 1997-05-28
MA24131A1 (fr) 1997-10-01
TR199700261A2 (xx) 1997-10-21
IL131645A0 (en) 2001-01-28
HUP9700708A3 (en) 2000-01-28
HN1997000045A (es) 1997-06-26
AU725786B2 (en) 2000-10-19
NO309092B1 (no) 2000-12-11
HRP970154A2 (en) 1998-04-30
YU12397A (en) 1999-11-22
CZ102297A3 (en) 1997-10-15
SV1997000025A (es) 1997-10-23
KR970070008A (ko) 1997-11-07
NO971512D0 (no) 1997-04-03
JPH1059972A (ja) 1998-03-03
NZ314497A (en) 1999-10-28
ZA972829B (en) 1997-10-31
MY126362A (en) 2006-09-29
DZ2201A1 (fr) 2002-12-03
PE42398A1 (es) 1998-10-12
PL319249A1 (en) 1997-10-13
EE9700078A (et) 1997-10-15

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees