TNSN97061A1 - NOUVEAUX PYRIMIDO [1,2 – a ] INDOLES. - Google Patents

NOUVEAUX PYRIMIDO [1,2 – a ] INDOLES.

Info

Publication number
TNSN97061A1
TNSN97061A1 TNTNSN97061A TNSN97061A TNSN97061A1 TN SN97061 A1 TNSN97061 A1 TN SN97061A1 TN TNSN97061 A TNTNSN97061 A TN TNSN97061A TN SN97061 A TNSN97061 A TN SN97061A TN SN97061 A1 TNSN97061 A1 TN SN97061A1
Authority
TN
Tunisia
Prior art keywords
indoles
pyrimido
new pyrimido
new
medicinal products
Prior art date
Application number
TNTNSN97061A
Other languages
English (en)
Inventor
Ultich Muller Dr
Peter Eckenberg Dr
Rudi Gruntzmann Dr
Hilmar Bischorff Dr
Dirk Denzer Dr
Stefan Wohlfeil Dr
Stefan Lohmer Dr
Ulrich Nielsch Dr
Peter Kolkhof Dr
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of TNSN97061A1 publication Critical patent/TNSN97061A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

LES PYRIMIDO [1,2-A] SELON L'INVENTION SONT PREPARES PAR REACTION DE DERIVES CONVENABLEMENT SUBSTITUES DE L'ACIDE PHENYLACETIQUE AVEC DES PHENYLGLYCINOLS. LES PYRIMIDO [1,2-A] INDOLES PEUVENT ETRE UTILISES COMME PRINCIPES ACTIFS DANS DES MEDICAMENTS EN PARTICULIER DANS DES MEDICAMENTS AYANT UNE ACTIVITE ANTIATHEROSCLEROTIQUE.
TNTNSN97061A 1996-04-04 1997-04-02 NOUVEAUX PYRIMIDO [1,2 – a ] INDOLES. TNSN97061A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19613550A DE19613550A1 (de) 1996-04-04 1996-04-04 Neue Pyrimido[1,2-a]indole

Publications (1)

Publication Number Publication Date
TNSN97061A1 true TNSN97061A1 (fr) 2005-03-15

Family

ID=7790502

Family Applications (1)

Application Number Title Priority Date Filing Date
TNTNSN97061A TNSN97061A1 (fr) 1996-04-04 1997-04-02 NOUVEAUX PYRIMIDO [1,2 – a ] INDOLES.

Country Status (33)

Country Link
US (1) US6114341A (fr)
EP (1) EP0799828A3 (fr)
JP (1) JPH1059972A (fr)
KR (1) KR970070008A (fr)
CN (2) CN1067393C (fr)
AR (1) AR006497A1 (fr)
AU (1) AU725786B2 (fr)
BG (1) BG62934B1 (fr)
BR (1) BR9701675A (fr)
CA (1) CA2201434A1 (fr)
CO (1) CO4520306A1 (fr)
CZ (1) CZ102297A3 (fr)
DE (1) DE19613550A1 (fr)
DZ (1) DZ2201A1 (fr)
EE (1) EE9700078A (fr)
HN (1) HN1997000045A (fr)
HR (1) HRP970154A2 (fr)
HU (1) HUP9700708A3 (fr)
ID (1) ID16520A (fr)
IL (3) IL131645A (fr)
MA (1) MA24131A1 (fr)
MY (1) MY126362A (fr)
NO (1) NO309092B1 (fr)
NZ (1) NZ314497A (fr)
PE (1) PE42398A1 (fr)
PL (1) PL319249A1 (fr)
SG (1) SG63698A1 (fr)
SK (1) SK42797A3 (fr)
SV (1) SV1997000025A (fr)
TN (1) TNSN97061A1 (fr)
TR (1) TR199700261A2 (fr)
YU (1) YU12397A (fr)
ZA (1) ZA972829B (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19826469A1 (de) * 1998-06-13 2000-05-25 Bayer Ag Verfahren zur Herstellung von 2,4-Dimethylcarbolin und 2,4-Dimethylpyrimido[1,2-a]indol
AU2001244635A1 (en) * 2000-03-30 2001-10-15 Yamanouchi Pharmaceutical Co..Ltd. Hydrazide derivatives
DE10030375A1 (de) * 2000-06-21 2002-01-03 Bayer Ag Verwendung von MTP-Inhibitoren zur Senkung von ppTRL
JP4254093B2 (ja) * 2001-10-17 2009-04-15 宇部興産株式会社 ５−ハロゲノインドールの製法
DE10349175A1 (de) * 2003-10-22 2005-05-19 Bayer Healthcare Ag Mittel zur Gewichtsreduktion
DK1725234T4 (en) 2004-03-05 2016-05-09 Univ Pennsylvania METHODS OF TREATING DISEASES OR DISEASES CONNECTED WITH HYPERLIPIDEMIA AND HYPERCOLESTEROLYMIA WITH MINIMIZATION OF SIDE EFFECTS
AU2005230397B2 (en) * 2004-04-09 2010-04-08 Elanco Animal Health Ireland Limited Intermittent dosing regimen for the treatment of overweight with MTP-inhibitors
CA3029306C (fr) 2005-05-12 2020-12-29 C.R. Bard Inc. Filtre amovible pour caillot sanguin ou embole
JP2008542255A (ja) * 2005-05-27 2008-11-27 ファイザー・プロダクツ・インク 肥満症の治療または体重減量の維持のためのカンナビノイド−１受容体アンタゴニストおよびミクロソームトリグリセリド輸送タンパク質阻害物質の併用
JP4851522B2 (ja) 2005-08-09 2012-01-11 シー・アール・バード・インコーポレーテッド 挿入型血栓フィルタ及びデリバリシステム
CA2626422A1 (fr) * 2005-10-18 2007-04-26 Aegerion Pharmaceuticals Methodes permettant de traiter les troubles associes a l'hyperlipidemie chez un mammifere
WO2007133366A2 (fr) 2006-05-02 2007-11-22 C. R. Bard, Inc. Filtre à veine cave formé à partir d'une feuille
AU2007338625A1 (en) * 2006-12-21 2008-07-03 Aegerion Pharmaceuticals, Inc. Methods for treating obesity with a combination comprising a MTP inhibitor and a cholesterol absorption inhibitor

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2200584A1 (de) * 1971-01-11 1972-07-27 Wyeth John & Brother Ltd Heterocyclische Verbindungen,Verfahren zu ihrer Herstellung und ihre Verwendung in pharmazeutischen Zubereitungen
ZA718536B (en) * 1971-01-11 1972-09-27 Wyeth John & Brother Ltd Heterocyclic compounds
GB8614246D0 (en) * 1986-06-11 1986-07-16 Wyeth John & Brother Ltd Substituted pyrimidoindoles
DE4112533A1 (de) * 1991-04-17 1992-10-22 Bayer Ag Verfahren zur herstellung von enantiomerenreinen substituierten (chinolin-2-yl-methoxy)phenyl-essigsaeuren
DE4200954A1 (de) * 1991-04-26 1992-10-29 Bayer Ag Heterocyclisch substituierte phenylessigsaeurederivate
DE4309968A1 (de) * 1993-03-26 1994-09-29 Bayer Ag Phenylglycinamide von heterocyclisch substituierten Phenylessigsäurederivaten
US5576342A (en) * 1992-03-13 1996-11-19 Bayer Aktiengesellschaft Phenylglycinamides of heterocyclically substitued phenylacetic acid derivatives
DE4208052A1 (de) * 1992-03-13 1993-09-16 Bayer Ag Imidazolyl substituierte phenylessigsaeureamide
DE4208051A1 (de) * 1992-03-13 1993-09-16 Bayer Ag Substituierte phenylessigsaeureamide
NZ257545A (en) * 1992-11-05 1997-01-29 Smithkline Beecham Plc Heterocyclic (especially piperidine) derivatives and pharmaceutical compositions
DE4302956A1 (de) * 1993-02-03 1994-08-04 Bayer Ag Substituierte Imidazo(4,5-b)pyridine und Benzimidazole

Also Published As

Publication number Publication date
CN1067393C (zh) 2001-06-20
AR006497A1 (es) 1999-08-25
ID16520A (id) 1997-10-09
MX9702445A (es) 1997-10-31
IL131645A (en) 2000-12-06
ZA972829B (en) 1997-10-31
MA24131A1 (fr) 1997-10-01
EP0799828A2 (fr) 1997-10-08
HN1997000045A (es) 1997-06-26
EP0799828A3 (fr) 1998-04-08
BG62934B1 (bg) 2000-11-30
SK42797A3 (en) 1997-11-05
HUP9700708A2 (hu) 1998-10-28
CN1176965A (zh) 1998-03-25
EE9700078A (et) 1997-10-15
YU12397A (en) 1999-11-22
AU725786B2 (en) 2000-10-19
HUP9700708A3 (en) 2000-01-28
NZ314497A (en) 1999-10-28
KR970070008A (ko) 1997-11-07
TR199700261A2 (xx) 1997-10-21
PE42398A1 (es) 1998-10-12
DZ2201A1 (fr) 2002-12-03
NO971512L (no) 1997-10-06
NO971512D0 (no) 1997-04-03
CO4520306A1 (es) 1997-10-15
HU9700708D0 (en) 1997-05-28
MY126362A (en) 2006-09-29
BG101379A (en) 1997-11-28
IL131645A0 (en) 2001-01-28
CN1312246A (zh) 2001-09-12
CA2201434A1 (fr) 1997-10-04
SG63698A1 (en) 1999-03-30
BR9701675A (pt) 1998-11-03
CZ102297A3 (en) 1997-10-15
HRP970154A2 (en) 1998-04-30
PL319249A1 (en) 1997-10-13
SV1997000025A (es) 1997-10-23
IL120590A0 (en) 1997-08-14
US6114341A (en) 2000-09-05
JPH1059972A (ja) 1998-03-03
AU1660397A (en) 1997-10-09
NO309092B1 (no) 2000-12-11
IL120590A (en) 2000-02-17
DE19613550A1 (de) 1997-10-09

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