IL131645A - Pyrimido ¬1,2-a¾indole derivatives and their preparation - Google Patents

Pyrimido ¬1,2-a¾indole derivatives and their preparation

Info

Publication number
IL131645A
IL131645A IL13164597A IL13164597A IL131645A IL 131645 A IL131645 A IL 131645A IL 13164597 A IL13164597 A IL 13164597A IL 13164597 A IL13164597 A IL 13164597A IL 131645 A IL131645 A IL 131645A
Authority
IL
Israel
Prior art keywords
pyrimido
derivatives
preparation
Prior art date
Application number
IL13164597A
Other languages
English (en)
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of IL131645A publication Critical patent/IL131645A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
IL13164597A 1996-04-04 1997-04-02 Pyrimido ¬1,2-a¾indole derivatives and their preparation IL131645A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19613550A DE19613550A1 (de) 1996-04-04 1996-04-04 Neue Pyrimido[1,2-a]indole
IL12059097A IL120590A (en) 1996-04-04 1997-04-02 N-(2-hydroxy-1-phenylethyl)pyrimido¬1,2-a¾indol-10-ylmethylphenyl-acetamides their preparation and pharmaceutical compositions containing them

Publications (1)

Publication Number Publication Date
IL131645A true IL131645A (en) 2000-12-06

Family

ID=7790502

Family Applications (3)

Application Number Title Priority Date Filing Date
IL12059097A IL120590A (en) 1996-04-04 1997-04-02 N-(2-hydroxy-1-phenylethyl)pyrimido¬1,2-a¾indol-10-ylmethylphenyl-acetamides their preparation and pharmaceutical compositions containing them
IL13164597A IL131645A (en) 1996-04-04 1997-04-02 Pyrimido ¬1,2-a¾indole derivatives and their preparation
IL13164599A IL131645A0 (en) 1996-04-04 1999-08-30 Pyrimido ¬1,2-a¾ indole derivaties and their preparation

Family Applications Before (1)

Application Number Title Priority Date Filing Date
IL12059097A IL120590A (en) 1996-04-04 1997-04-02 N-(2-hydroxy-1-phenylethyl)pyrimido¬1,2-a¾indol-10-ylmethylphenyl-acetamides their preparation and pharmaceutical compositions containing them

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL13164599A IL131645A0 (en) 1996-04-04 1999-08-30 Pyrimido ¬1,2-a¾ indole derivaties and their preparation

Country Status (33)

Country Link
US (1) US6114341A (xx)
EP (1) EP0799828A3 (xx)
JP (1) JPH1059972A (xx)
KR (1) KR970070008A (xx)
CN (2) CN1067393C (xx)
AR (1) AR006497A1 (xx)
AU (1) AU725786B2 (xx)
BG (1) BG62934B1 (xx)
BR (1) BR9701675A (xx)
CA (1) CA2201434A1 (xx)
CO (1) CO4520306A1 (xx)
CZ (1) CZ102297A3 (xx)
DE (1) DE19613550A1 (xx)
DZ (1) DZ2201A1 (xx)
EE (1) EE9700078A (xx)
HN (1) HN1997000045A (xx)
HR (1) HRP970154A2 (xx)
HU (1) HUP9700708A3 (xx)
ID (1) ID16520A (xx)
IL (3) IL120590A (xx)
MA (1) MA24131A1 (xx)
MY (1) MY126362A (xx)
NO (1) NO309092B1 (xx)
NZ (1) NZ314497A (xx)
PE (1) PE42398A1 (xx)
PL (1) PL319249A1 (xx)
SG (1) SG63698A1 (xx)
SK (1) SK42797A3 (xx)
SV (1) SV1997000025A (xx)
TN (1) TNSN97061A1 (xx)
TR (1) TR199700261A2 (xx)
YU (1) YU12397A (xx)
ZA (1) ZA972829B (xx)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19826469A1 (de) * 1998-06-13 2000-05-25 Bayer Ag Verfahren zur Herstellung von 2,4-Dimethylcarbolin und 2,4-Dimethylpyrimido[1,2-a]indol
WO2001074817A1 (fr) * 2000-03-30 2001-10-11 Yamanouchi Pharmaceutical Co., Ltd. Derives d'hydrazide
DE10030375A1 (de) * 2000-06-21 2002-01-03 Bayer Ag Verwendung von MTP-Inhibitoren zur Senkung von ppTRL
JP4254093B2 (ja) * 2001-10-17 2009-04-15 宇部興産株式会社 ５−ハロゲノインドールの製法
DE10349175A1 (de) * 2003-10-22 2005-05-19 Bayer Healthcare Ag Mittel zur Gewichtsreduktion
WO2005087234A1 (en) 2004-03-05 2005-09-22 The Trustees Of The University Of Pennsylvania Methods for treating disorders or diseases associated with hyperlipidemia and hypercholesterolemia while minimizing side-effects
WO2005097131A2 (en) * 2004-04-09 2005-10-20 Janssen Pharmaceutica N.V. Intermittent dosing regimen for the treatment of overweight with mtp-inhibitors
CA2607580C (en) 2005-05-12 2016-12-20 C.R. Bard Inc. Removable embolus blood clot filter
CA2609783A1 (en) * 2005-05-27 2006-12-07 Pfizer Products Inc. Combination of a cannabinoid-1- receptor-antagonist and a microsomal triglyceride transfer protein inhibitor for treating obesity or mainataining weight loss
CA2616818C (en) 2005-08-09 2014-08-05 C.R. Bard, Inc. Embolus blood clot filter and delivery system
WO2007047880A2 (en) * 2005-10-18 2007-04-26 Aegerion Pharmaceuticals Compositions for lowering serum cholesterol and/or triglycerides
WO2007133366A2 (en) 2006-05-02 2007-11-22 C. R. Bard, Inc. Vena cava filter formed from a sheet
EP2120927A1 (en) * 2006-12-21 2009-11-25 Aegerion Pharmaceuticals, Inc. Methods for treating obesity with a combination comprising a mtp inhibitor and a cholesterol absorption inhibitor

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2200584A1 (de) * 1971-01-11 1972-07-27 Wyeth John & Brother Ltd Heterocyclische Verbindungen,Verfahren zu ihrer Herstellung und ihre Verwendung in pharmazeutischen Zubereitungen
ZA718536B (en) * 1971-01-11 1972-09-27 Wyeth John & Brother Ltd Heterocyclic compounds
GB8614246D0 (en) * 1986-06-11 1986-07-16 Wyeth John & Brother Ltd Substituted pyrimidoindoles
DE4112533A1 (de) * 1991-04-17 1992-10-22 Bayer Ag Verfahren zur herstellung von enantiomerenreinen substituierten (chinolin-2-yl-methoxy)phenyl-essigsaeuren
DE4200954A1 (de) * 1991-04-26 1992-10-29 Bayer Ag Heterocyclisch substituierte phenylessigsaeurederivate
DE4208052A1 (de) * 1992-03-13 1993-09-16 Bayer Ag Imidazolyl substituierte phenylessigsaeureamide
DE4208051A1 (de) * 1992-03-13 1993-09-16 Bayer Ag Substituierte phenylessigsaeureamide
US5576342A (en) * 1992-03-13 1996-11-19 Bayer Aktiengesellschaft Phenylglycinamides of heterocyclically substitued phenylacetic acid derivatives
DE4309968A1 (de) * 1993-03-26 1994-09-29 Bayer Ag Phenylglycinamide von heterocyclisch substituierten Phenylessigsäurederivaten
AU680453B2 (en) * 1992-11-05 1997-07-31 Smithkline Beecham Plc Piperidine derivatives as 5-HT4 receptor antagonists
DE4302956A1 (de) * 1993-02-03 1994-08-04 Bayer Ag Substituierte Imidazo(4,5-b)pyridine und Benzimidazole

Also Published As

Publication number Publication date
PE42398A1 (es) 1998-10-12
CN1312246A (zh) 2001-09-12
SK42797A3 (en) 1997-11-05
CN1067393C (zh) 2001-06-20
MA24131A1 (fr) 1997-10-01
BG101379A (en) 1997-11-28
BG62934B1 (bg) 2000-11-30
CO4520306A1 (es) 1997-10-15
IL120590A (en) 2000-02-17
HUP9700708A3 (en) 2000-01-28
NO971512D0 (no) 1997-04-03
AU1660397A (en) 1997-10-09
EE9700078A (et) 1997-10-15
HUP9700708A2 (hu) 1998-10-28
HN1997000045A (es) 1997-06-26
US6114341A (en) 2000-09-05
MY126362A (en) 2006-09-29
AR006497A1 (es) 1999-08-25
DE19613550A1 (de) 1997-10-09
MX9702445A (es) 1997-10-31
HU9700708D0 (en) 1997-05-28
AU725786B2 (en) 2000-10-19
CN1176965A (zh) 1998-03-25
JPH1059972A (ja) 1998-03-03
KR970070008A (ko) 1997-11-07
NZ314497A (en) 1999-10-28
CZ102297A3 (en) 1997-10-15
TNSN97061A1 (fr) 2005-03-15
DZ2201A1 (fr) 2002-12-03
NO971512L (no) 1997-10-06
ZA972829B (en) 1997-10-31
YU12397A (en) 1999-11-22
EP0799828A2 (de) 1997-10-08
TR199700261A2 (xx) 1997-10-21
SV1997000025A (es) 1997-10-23
CA2201434A1 (en) 1997-10-04
IL120590A0 (en) 1997-08-14
EP0799828A3 (de) 1998-04-08
BR9701675A (pt) 1998-11-03
PL319249A1 (en) 1997-10-13
HRP970154A2 (en) 1998-04-30
ID16520A (id) 1997-10-09
IL131645A0 (en) 2001-01-28
SG63698A1 (en) 1999-03-30
NO309092B1 (no) 2000-12-11

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees