IL120342A0 - Bis- (2 - haloethyl) aminophenyl substituted distamycin derivatives as antitumor and antiviral agents - Google Patents
Bis- (2 - haloethyl) aminophenyl substituted distamycin derivatives as antitumor and antiviral agentsInfo
- Publication number
- IL120342A0 IL120342A0 IL12034296A IL12034296A IL120342A0 IL 120342 A0 IL120342 A0 IL 120342A0 IL 12034296 A IL12034296 A IL 12034296A IL 12034296 A IL12034296 A IL 12034296A IL 120342 A0 IL120342 A0 IL 120342A0
- Authority
- IL
- Israel
- Prior art keywords
- haloethyl
- antitumor
- bis
- antiviral agents
- distamycin derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9514993.6A GB9514993D0 (en) | 1995-07-21 | 1995-07-21 | Site specific phenyl nitrogen mustards |
PCT/EP1996/002659 WO1997003957A1 (en) | 1995-07-21 | 1996-06-19 | Bis-(2-haloethyl)aminophenyl substituted distamycin derivatives as antitumor and antiviral agents |
Publications (1)
Publication Number | Publication Date |
---|---|
IL120342A0 true IL120342A0 (en) | 1997-06-10 |
Family
ID=10778062
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL12034296A IL120342A0 (en) | 1995-07-21 | 1996-06-19 | Bis- (2 - haloethyl) aminophenyl substituted distamycin derivatives as antitumor and antiviral agents |
Country Status (18)
Country | Link |
---|---|
EP (1) | EP0787126A1 (pt) |
JP (1) | JPH10506410A (pt) |
KR (1) | KR970706251A (pt) |
CN (1) | CN1159183A (pt) |
AR (1) | AR003456A1 (pt) |
AU (1) | AU6357996A (pt) |
BR (1) | BR9606528A (pt) |
CA (1) | CA2199635A1 (pt) |
EA (1) | EA000033B1 (pt) |
GB (1) | GB9514993D0 (pt) |
HU (1) | HUP9702393A3 (pt) |
IL (1) | IL120342A0 (pt) |
MX (1) | MX9701949A (pt) |
NO (1) | NO971142L (pt) |
PL (1) | PL319352A1 (pt) |
TW (1) | TW367325B (pt) |
WO (1) | WO1997003957A1 (pt) |
ZA (1) | ZA965028B (pt) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6635417B1 (en) | 1996-07-31 | 2003-10-21 | California Institute Of Technology | Complex formation between DSDNA and oligomer of cyclic heterocycles |
JP2001513759A (ja) | 1996-02-26 | 2001-09-04 | カリフォルニア・インスティチュート・オブ・テクノロジー | 二本鎖dnaの副溝において結合する改良されたポリアミド |
US5998140A (en) * | 1996-07-31 | 1999-12-07 | The Scripps Research Institute | Complex formation between dsDNA and oligomer of cyclic heterocycles |
GB9623522D0 (en) * | 1996-11-11 | 1997-01-08 | Pharmacia & Upjohn Spa | Benzoheterocycle distamycin derivatives process for preparing them and their use as antitumour and antiviral agents |
GB9816652D0 (en) * | 1998-07-30 | 1998-09-30 | Pharmacia & Upjohn Spa | Sulfurated distamycin derivatives process for preparing them and their use as antitumor agents |
GB9907414D0 (en) | 1999-03-31 | 1999-05-26 | Cancer Res Campaign Tech | Improvements relating to prodrugs |
US6559125B1 (en) | 2000-01-28 | 2003-05-06 | California Institute Of Technology | Polyamide-alkylator conjugates and related products and method |
US20030236198A1 (en) | 2001-06-13 | 2003-12-25 | Genesoft, Inc. | Antipathogenic benzamide compounds |
ATE425753T1 (de) | 2002-08-02 | 2009-04-15 | Genesoft Pharmaceuticals Inc | Biaryl-verbindungen mit antiinfektiver wirkung |
US7265129B2 (en) | 2002-10-25 | 2007-09-04 | Genesoft Pharmaceuticals, Inc. | Anti-infective biaryl compounds |
JP2006509027A (ja) | 2002-12-10 | 2006-03-16 | オーシェント ファーマシューティカルズ コーポレーション | (ピロールカルボキサミド)−(ベンズアミド)−(イミダゾールカルボキサミド)モチーフを有する抗菌化合物 |
EP2792355A1 (en) | 2013-04-17 | 2014-10-22 | Albert-Ludwigs-Universität Freiburg | Compounds for use as bromodomain inhibitors |
CN115414356A (zh) * | 2022-09-27 | 2022-12-02 | 广西科技大学 | 一种茚并吡咯类衍生物在制备抗肿瘤药物组合物中的应用 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8612218D0 (en) * | 1986-05-20 | 1986-06-25 | Erba Farmitalia | Site specific alkylating agents |
-
1995
- 1995-07-21 GB GBGB9514993.6A patent/GB9514993D0/en active Pending
-
1996
- 1996-06-13 ZA ZA965028A patent/ZA965028B/xx unknown
- 1996-06-18 TW TW085107334A patent/TW367325B/zh active
- 1996-06-19 BR BR9606528A patent/BR9606528A/pt not_active Application Discontinuation
- 1996-06-19 MX MX9701949A patent/MX9701949A/es unknown
- 1996-06-19 EA EA199700046A patent/EA000033B1/ru not_active IP Right Cessation
- 1996-06-19 CA CA002199635A patent/CA2199635A1/en not_active Abandoned
- 1996-06-19 PL PL96319352A patent/PL319352A1/xx unknown
- 1996-06-19 IL IL12034296A patent/IL120342A0/xx unknown
- 1996-06-19 WO PCT/EP1996/002659 patent/WO1997003957A1/en not_active Application Discontinuation
- 1996-06-19 JP JP9506209A patent/JPH10506410A/ja active Pending
- 1996-06-19 EP EP96922849A patent/EP0787126A1/en not_active Withdrawn
- 1996-06-19 HU HU9702393A patent/HUP9702393A3/hu unknown
- 1996-06-19 CN CN96190784A patent/CN1159183A/zh active Pending
- 1996-06-19 AU AU63579/96A patent/AU6357996A/en not_active Abandoned
- 1996-07-15 AR ARP960103583A patent/AR003456A1/es unknown
- 1996-09-19 KR KR1019970701796A patent/KR970706251A/ko not_active Application Discontinuation
-
1997
- 1997-03-12 NO NO971142A patent/NO971142L/no unknown
Also Published As
Publication number | Publication date |
---|---|
CA2199635A1 (en) | 1997-02-06 |
NO971142D0 (no) | 1997-03-12 |
HUP9702393A3 (en) | 1998-05-28 |
JPH10506410A (ja) | 1998-06-23 |
EP0787126A1 (en) | 1997-08-06 |
TW367325B (en) | 1999-08-21 |
WO1997003957A1 (en) | 1997-02-06 |
KR970706251A (ko) | 1997-11-03 |
GB9514993D0 (en) | 1995-09-20 |
AR003456A1 (es) | 1998-08-05 |
CN1159183A (zh) | 1997-09-10 |
EA199700046A1 (ru) | 1997-12-30 |
EA000033B1 (ru) | 1998-02-26 |
ZA965028B (en) | 1997-01-23 |
MX9701949A (es) | 1997-06-28 |
AU6357996A (en) | 1997-02-18 |
HUP9702393A2 (hu) | 1998-04-28 |
PL319352A1 (en) | 1997-08-04 |
BR9606528A (pt) | 1997-12-23 |
NO971142L (no) | 1997-03-12 |
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