IL120342A0 - Bis- (2 - haloethyl) aminophenyl substituted distamycin derivatives as antitumor and antiviral agents - Google Patents

Bis- (2 - haloethyl) aminophenyl substituted distamycin derivatives as antitumor and antiviral agents

Info

Publication number
IL120342A0
IL120342A0 IL12034296A IL12034296A IL120342A0 IL 120342 A0 IL120342 A0 IL 120342A0 IL 12034296 A IL12034296 A IL 12034296A IL 12034296 A IL12034296 A IL 12034296A IL 120342 A0 IL120342 A0 IL 120342A0
Authority
IL
Israel
Prior art keywords
haloethyl
antitumor
bis
antiviral agents
distamycin derivatives
Prior art date
Application number
IL12034296A
Other languages
English (en)
Original Assignee
Pharmacia & Upjohn Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Spa filed Critical Pharmacia & Upjohn Spa
Publication of IL120342A0 publication Critical patent/IL120342A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL12034296A 1995-07-21 1996-06-19 Bis- (2 - haloethyl) aminophenyl substituted distamycin derivatives as antitumor and antiviral agents IL120342A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9514993.6A GB9514993D0 (en) 1995-07-21 1995-07-21 Site specific phenyl nitrogen mustards
PCT/EP1996/002659 WO1997003957A1 (en) 1995-07-21 1996-06-19 Bis-(2-haloethyl)aminophenyl substituted distamycin derivatives as antitumor and antiviral agents

Publications (1)

Publication Number Publication Date
IL120342A0 true IL120342A0 (en) 1997-06-10

Family

ID=10778062

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12034296A IL120342A0 (en) 1995-07-21 1996-06-19 Bis- (2 - haloethyl) aminophenyl substituted distamycin derivatives as antitumor and antiviral agents

Country Status (18)

Country Link
EP (1) EP0787126A1 (xx)
JP (1) JPH10506410A (xx)
KR (1) KR970706251A (xx)
CN (1) CN1159183A (xx)
AR (1) AR003456A1 (xx)
AU (1) AU6357996A (xx)
BR (1) BR9606528A (xx)
CA (1) CA2199635A1 (xx)
EA (1) EA000033B1 (xx)
GB (1) GB9514993D0 (xx)
HU (1) HUP9702393A3 (xx)
IL (1) IL120342A0 (xx)
MX (1) MX9701949A (xx)
NO (1) NO971142L (xx)
PL (1) PL319352A1 (xx)
TW (1) TW367325B (xx)
WO (1) WO1997003957A1 (xx)
ZA (1) ZA965028B (xx)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6635417B1 (en) 1996-07-31 2003-10-21 California Institute Of Technology Complex formation between DSDNA and oligomer of cyclic heterocycles
JP2001513759A (ja) 1996-02-26 2001-09-04 カリフォルニア・インスティチュート・オブ・テクノロジー 二本鎖dnaの副溝において結合する改良されたポリアミド
US5998140A (en) * 1996-07-31 1999-12-07 The Scripps Research Institute Complex formation between dsDNA and oligomer of cyclic heterocycles
GB9623522D0 (en) * 1996-11-11 1997-01-08 Pharmacia & Upjohn Spa Benzoheterocycle distamycin derivatives process for preparing them and their use as antitumour and antiviral agents
GB9816652D0 (en) * 1998-07-30 1998-09-30 Pharmacia & Upjohn Spa Sulfurated distamycin derivatives process for preparing them and their use as antitumor agents
GB9907414D0 (en) 1999-03-31 1999-05-26 Cancer Res Campaign Tech Improvements relating to prodrugs
US6559125B1 (en) 2000-01-28 2003-05-06 California Institute Of Technology Polyamide-alkylator conjugates and related products and method
US20030236198A1 (en) 2001-06-13 2003-12-25 Genesoft, Inc. Antipathogenic benzamide compounds
ATE425753T1 (de) 2002-08-02 2009-04-15 Genesoft Pharmaceuticals Inc Biaryl-verbindungen mit antiinfektiver wirkung
US7265129B2 (en) 2002-10-25 2007-09-04 Genesoft Pharmaceuticals, Inc. Anti-infective biaryl compounds
JP2006509027A (ja) 2002-12-10 2006-03-16 オーシェント ファーマシューティカルズ コーポレーション (ピロールカルボキサミド)−(ベンズアミド)−(イミダゾールカルボキサミド)モチーフを有する抗菌化合物
EP2792355A1 (en) 2013-04-17 2014-10-22 Albert-Ludwigs-Universität Freiburg Compounds for use as bromodomain inhibitors
CN115414356A (zh) * 2022-09-27 2022-12-02 广西科技大学 一种茚并吡咯类衍生物在制备抗肿瘤药物组合物中的应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8612218D0 (en) * 1986-05-20 1986-06-25 Erba Farmitalia Site specific alkylating agents

Also Published As

Publication number Publication date
CA2199635A1 (en) 1997-02-06
NO971142D0 (no) 1997-03-12
HUP9702393A3 (en) 1998-05-28
JPH10506410A (ja) 1998-06-23
EP0787126A1 (en) 1997-08-06
TW367325B (en) 1999-08-21
WO1997003957A1 (en) 1997-02-06
KR970706251A (ko) 1997-11-03
GB9514993D0 (en) 1995-09-20
AR003456A1 (es) 1998-08-05
CN1159183A (zh) 1997-09-10
EA199700046A1 (ru) 1997-12-30
EA000033B1 (ru) 1998-02-26
ZA965028B (en) 1997-01-23
MX9701949A (es) 1997-06-28
AU6357996A (en) 1997-02-18
HUP9702393A2 (hu) 1998-04-28
PL319352A1 (en) 1997-08-04
BR9606528A (pt) 1997-12-23
NO971142L (no) 1997-03-12

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