IL120342A0 - Bis- (2 - haloethyl) aminophenyl substituted distamycin derivatives as antitumor and antiviral agents - Google Patents

Bis- (2 - haloethyl) aminophenyl substituted distamycin derivatives as antitumor and antiviral agents

Info

Publication number
IL120342A0
IL120342A0 IL12034296A IL12034296A IL120342A0 IL 120342 A0 IL120342 A0 IL 120342A0 IL 12034296 A IL12034296 A IL 12034296A IL 12034296 A IL12034296 A IL 12034296A IL 120342 A0 IL120342 A0 IL 120342A0
Authority
IL
Israel
Prior art keywords
haloethyl
antitumor
bis
antiviral agents
distamycin derivatives
Prior art date
Application number
IL12034296A
Original Assignee
Pharmacia & Upjohn Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Spa filed Critical Pharmacia & Upjohn Spa
Publication of IL120342A0 publication Critical patent/IL120342A0/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
IL12034296A 1995-07-21 1996-06-19 Bis- (2 - haloethyl) aminophenyl substituted distamycin derivatives as antitumor and antiviral agents IL120342A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9514993.6A GB9514993D0 (en) 1995-07-21 1995-07-21 Site specific phenyl nitrogen mustards
PCT/EP1996/002659 WO1997003957A1 (en) 1995-07-21 1996-06-19 Bis-(2-haloethyl)aminophenyl substituted distamycin derivatives as antitumor and antiviral agents

Publications (1)

Publication Number Publication Date
IL120342A0 true IL120342A0 (en) 1997-06-10

Family

ID=10778062

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12034296A IL120342A0 (en) 1995-07-21 1996-06-19 Bis- (2 - haloethyl) aminophenyl substituted distamycin derivatives as antitumor and antiviral agents

Country Status (18)

Country Link
EP (1) EP0787126A1 (en)
JP (1) JPH10506410A (en)
KR (1) KR970706251A (en)
CN (1) CN1159183A (en)
AR (1) AR003456A1 (en)
AU (1) AU6357996A (en)
BR (1) BR9606528A (en)
CA (1) CA2199635A1 (en)
EA (1) EA000033B1 (en)
GB (1) GB9514993D0 (en)
HU (1) HUP9702393A3 (en)
IL (1) IL120342A0 (en)
MX (1) MX9701949A (en)
NO (1) NO971142D0 (en)
PL (1) PL319352A1 (en)
TW (1) TW367325B (en)
WO (1) WO1997003957A1 (en)
ZA (1) ZA965028B (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6635417B1 (en) 1996-07-31 2003-10-21 California Institute Of Technology Complex formation between DSDNA and oligomer of cyclic heterocycles
AU734715B2 (en) 1996-02-26 2001-06-21 California Institute Of Technology Improved polyamides for binding in the minor groove of double stranded DNA
US5998140A (en) * 1996-07-31 1999-12-07 The Scripps Research Institute Complex formation between dsDNA and oligomer of cyclic heterocycles
GB9623522D0 (en) * 1996-11-11 1997-01-08 Pharmacia & Upjohn Spa Benzoheterocycle distamycin derivatives process for preparing them and their use as antitumour and antiviral agents
GB9816652D0 (en) * 1998-07-30 1998-09-30 Pharmacia & Upjohn Spa Sulfurated distamycin derivatives process for preparing them and their use as antitumor agents
GB9907414D0 (en) * 1999-03-31 1999-05-26 Cancer Res Campaign Tech Improvements relating to prodrugs
US6559125B1 (en) 2000-01-28 2003-05-06 California Institute Of Technology Polyamide-alkylator conjugates and related products and method
WO2002101007A2 (en) 2001-06-13 2002-12-19 Genesoft Pharmaceuticals, Inc Antipathogenic benzamide compounds
WO2004012736A1 (en) 2002-08-02 2004-02-12 Genesoft Pharmaceuticals, Inc. Biaryl compounds having anti-infective activity
EP1562931A2 (en) 2002-10-25 2005-08-17 Genesoft Pharmaceuticals, Inc. Anti-infective biaryl compounds
JP2006509027A (en) 2002-12-10 2006-03-16 オーシェント ファーマシューティカルズ コーポレーション Antibacterial compound having (pyrrolecarboxamide)-(benzamide)-(imidazolecarboxamide) motif
EP2792355A1 (en) 2013-04-17 2014-10-22 Albert-Ludwigs-Universität Freiburg Compounds for use as bromodomain inhibitors
CN115414356A (en) * 2022-09-27 2022-12-02 广西科技大学 Application of indenopyrrole derivatives in preparation of antitumor pharmaceutical composition

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8612218D0 (en) * 1986-05-20 1986-06-25 Erba Farmitalia Site specific alkylating agents

Also Published As

Publication number Publication date
KR970706251A (en) 1997-11-03
GB9514993D0 (en) 1995-09-20
HUP9702393A2 (en) 1998-04-28
EP0787126A1 (en) 1997-08-06
WO1997003957A1 (en) 1997-02-06
TW367325B (en) 1999-08-21
MX9701949A (en) 1997-06-28
CN1159183A (en) 1997-09-10
ZA965028B (en) 1997-01-23
AU6357996A (en) 1997-02-18
HUP9702393A3 (en) 1998-05-28
NO971142L (en) 1997-03-12
NO971142D0 (en) 1997-03-12
BR9606528A (en) 1997-12-23
EA000033B1 (en) 1998-02-26
EA199700046A1 (en) 1997-12-30
JPH10506410A (en) 1998-06-23
AR003456A1 (en) 1998-08-05
CA2199635A1 (en) 1997-02-06
PL319352A1 (en) 1997-08-04

Similar Documents

Publication Publication Date Title
AP9600816A0 (en) Substituted N-indole-2-carbonyl)-B-alanimamides and derivatives as antidiabetic agents
IL113193A0 (en) Nitrogen derivatives
NZ297211A (en) Benzylamine derivatives
IL126381A (en) Heterocyclic azahexane derivatives and antiviral compositions containing them
HU9501809D0 (en) Antiviral indole derivatives
IL120342A0 (en) Bis- (2 - haloethyl) aminophenyl substituted distamycin derivatives as antitumor and antiviral agents
IL126840A0 (en) Distamycin derivatives process for preparing them and their use as antitumor and antiviral agents
IL114267A0 (en) Antiviral agents
HU9700116D0 (en) Difluorostatone antiviral agents
AU1595997A (en) Thienoxazinone derivatives useful as antiviral agents
PL314008A1 (en) Derivatives of flavine as antiviral agents
EP0881878A4 (en) Arylhydrazone derivatives useful as antibacterial agents
IL112631A0 (en) Derivatives of 2-imidazoline-5-one fungicides
HUP9902883A3 (en) Bis/acridinecarboxamide/ and bis/phenazinecarboxamide/ derivatives as antitumour agents, preparation and use thereof
AU4347596A (en) Thienoxazinone derivatives useful as antiviral agents
HU9603105D0 (en) Adenosine derivatives
GB9214603D0 (en) 4-oxa-1-azabicyclo (3,2,0) heptan-7-one derivatives as antitumor agents
AU3395295A (en) Alkaloids and their antiviral agents
GB9926138D0 (en) Diphenylacetic acid derivatives and their use as antiviral agents
IL122150A0 (en) Antiviral agents
ZA951336B (en) Antiviral agents
ZA97568B (en) Distamycin derivatives process for preparing them and their use as antitumor and antiviral agents
AUPM405694A0 (en) Antiviral agents
AUPM565694A0 (en) Antiviral agents
AU1801095A (en) Antiviral agents