AU6357996A - Bis-(2-haloethyl)aminophenyl substituted distamycin derivatives as antitumor and antiviral agents - Google Patents
Bis-(2-haloethyl)aminophenyl substituted distamycin derivatives as antitumor and antiviral agentsInfo
- Publication number
- AU6357996A AU6357996A AU63579/96A AU6357996A AU6357996A AU 6357996 A AU6357996 A AU 6357996A AU 63579/96 A AU63579/96 A AU 63579/96A AU 6357996 A AU6357996 A AU 6357996A AU 6357996 A AU6357996 A AU 6357996A
- Authority
- AU
- Australia
- Prior art keywords
- haloethyl
- antitumor
- bis
- antiviral agents
- distamycin derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 230000000259 anti-tumor effect Effects 0.000 title 1
- 239000002246 antineoplastic agent Substances 0.000 title 1
- 239000003443 antiviral agent Substances 0.000 title 1
- UPBAOYRENQEPJO-UHFFFAOYSA-N n-[5-[[5-[(3-amino-3-iminopropyl)carbamoyl]-1-methylpyrrol-3-yl]carbamoyl]-1-methylpyrrol-3-yl]-4-formamido-1-methylpyrrole-2-carboxamide Chemical class CN1C=C(NC=O)C=C1C(=O)NC1=CN(C)C(C(=O)NC2=CN(C)C(C(=O)NCCC(N)=N)=C2)=C1 UPBAOYRENQEPJO-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9514993.6A GB9514993D0 (en) | 1995-07-21 | 1995-07-21 | Site specific phenyl nitrogen mustards |
| GB9514993 | 1995-07-21 | ||
| PCT/EP1996/002659 WO1997003957A1 (en) | 1995-07-21 | 1996-06-19 | Bis-(2-haloethyl)aminophenyl substituted distamycin derivatives as antitumor and antiviral agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU6357996A true AU6357996A (en) | 1997-02-18 |
Family
ID=10778062
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU63579/96A Abandoned AU6357996A (en) | 1995-07-21 | 1996-06-19 | Bis-(2-haloethyl)aminophenyl substituted distamycin derivatives as antitumor and antiviral agents |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0787126A1 (en) |
| JP (1) | JPH10506410A (en) |
| KR (1) | KR970706251A (en) |
| CN (1) | CN1159183A (en) |
| AR (1) | AR003456A1 (en) |
| AU (1) | AU6357996A (en) |
| BR (1) | BR9606528A (en) |
| CA (1) | CA2199635A1 (en) |
| EA (1) | EA000033B1 (en) |
| GB (1) | GB9514993D0 (en) |
| HU (1) | HUP9702393A3 (en) |
| IL (1) | IL120342A0 (en) |
| MX (1) | MX9701949A (en) |
| NO (1) | NO971142D0 (en) |
| PL (1) | PL319352A1 (en) |
| TW (1) | TW367325B (en) |
| WO (1) | WO1997003957A1 (en) |
| ZA (1) | ZA965028B (en) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6635417B1 (en) | 1996-07-31 | 2003-10-21 | California Institute Of Technology | Complex formation between DSDNA and oligomer of cyclic heterocycles |
| AU734715B2 (en) | 1996-02-26 | 2001-06-21 | California Institute Of Technology | Improved polyamides for binding in the minor groove of double stranded DNA |
| US5998140A (en) * | 1996-07-31 | 1999-12-07 | The Scripps Research Institute | Complex formation between dsDNA and oligomer of cyclic heterocycles |
| GB9623522D0 (en) * | 1996-11-11 | 1997-01-08 | Pharmacia & Upjohn Spa | Benzoheterocycle distamycin derivatives process for preparing them and their use as antitumour and antiviral agents |
| GB9816652D0 (en) * | 1998-07-30 | 1998-09-30 | Pharmacia & Upjohn Spa | Sulfurated distamycin derivatives process for preparing them and their use as antitumor agents |
| GB9907414D0 (en) * | 1999-03-31 | 1999-05-26 | Cancer Res Campaign Tech | Improvements relating to prodrugs |
| US6559125B1 (en) | 2000-01-28 | 2003-05-06 | California Institute Of Technology | Polyamide-alkylator conjugates and related products and method |
| WO2002101007A2 (en) | 2001-06-13 | 2002-12-19 | Genesoft Pharmaceuticals, Inc | Antipathogenic benzamide compounds |
| WO2004012736A1 (en) | 2002-08-02 | 2004-02-12 | Genesoft Pharmaceuticals, Inc. | Biaryl compounds having anti-infective activity |
| EP1562931A2 (en) | 2002-10-25 | 2005-08-17 | Genesoft Pharmaceuticals, Inc. | Anti-infective biaryl compounds |
| JP2006509027A (en) | 2002-12-10 | 2006-03-16 | オーシェント ファーマシューティカルズ コーポレーション | Antibacterial compound having (pyrrolecarboxamide)-(benzamide)-(imidazolecarboxamide) motif |
| EP2792355A1 (en) | 2013-04-17 | 2014-10-22 | Albert-Ludwigs-Universität Freiburg | Compounds for use as bromodomain inhibitors |
| CN115414356A (en) * | 2022-09-27 | 2022-12-02 | 广西科技大学 | Application of indenopyrrole derivatives in preparation of antitumor pharmaceutical composition |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8612218D0 (en) * | 1986-05-20 | 1986-06-25 | Erba Farmitalia | Site specific alkylating agents |
-
1995
- 1995-07-21 GB GBGB9514993.6A patent/GB9514993D0/en active Pending
-
1996
- 1996-06-13 ZA ZA965028A patent/ZA965028B/en unknown
- 1996-06-18 TW TW085107334A patent/TW367325B/en active
- 1996-06-19 HU HU9702393A patent/HUP9702393A3/en unknown
- 1996-06-19 EP EP96922849A patent/EP0787126A1/en not_active Withdrawn
- 1996-06-19 CN CN96190784A patent/CN1159183A/en active Pending
- 1996-06-19 BR BR9606528A patent/BR9606528A/en not_active Application Discontinuation
- 1996-06-19 IL IL12034296A patent/IL120342A0/en unknown
- 1996-06-19 WO PCT/EP1996/002659 patent/WO1997003957A1/en not_active Application Discontinuation
- 1996-06-19 CA CA002199635A patent/CA2199635A1/en not_active Abandoned
- 1996-06-19 JP JP9506209A patent/JPH10506410A/en active Pending
- 1996-06-19 MX MX9701949A patent/MX9701949A/en unknown
- 1996-06-19 AU AU63579/96A patent/AU6357996A/en not_active Abandoned
- 1996-06-19 EA EA199700046A patent/EA000033B1/en not_active IP Right Cessation
- 1996-06-19 PL PL96319352A patent/PL319352A1/en unknown
- 1996-07-15 AR ARP960103583A patent/AR003456A1/en unknown
- 1996-09-19 KR KR1019970701796A patent/KR970706251A/en not_active Application Discontinuation
-
1997
- 1997-03-12 NO NO971142A patent/NO971142D0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR970706251A (en) | 1997-11-03 |
| GB9514993D0 (en) | 1995-09-20 |
| HUP9702393A2 (en) | 1998-04-28 |
| EP0787126A1 (en) | 1997-08-06 |
| WO1997003957A1 (en) | 1997-02-06 |
| TW367325B (en) | 1999-08-21 |
| MX9701949A (en) | 1997-06-28 |
| IL120342A0 (en) | 1997-06-10 |
| CN1159183A (en) | 1997-09-10 |
| ZA965028B (en) | 1997-01-23 |
| HUP9702393A3 (en) | 1998-05-28 |
| NO971142L (en) | 1997-03-12 |
| NO971142D0 (en) | 1997-03-12 |
| BR9606528A (en) | 1997-12-23 |
| EA000033B1 (en) | 1998-02-26 |
| EA199700046A1 (en) | 1997-12-30 |
| JPH10506410A (en) | 1998-06-23 |
| AR003456A1 (en) | 1998-08-05 |
| CA2199635A1 (en) | 1997-02-06 |
| PL319352A1 (en) | 1997-08-04 |
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