PL319352A1 - Bis-(2-halogenoethyl) aminophenyl group substituted derivatives of distamycin as anticarcinogenic and antiviral drugs - Google Patents

Bis-(2-halogenoethyl) aminophenyl group substituted derivatives of distamycin as anticarcinogenic and antiviral drugs

Info

Publication number
PL319352A1
PL319352A1 PL96319352A PL31935296A PL319352A1 PL 319352 A1 PL319352 A1 PL 319352A1 PL 96319352 A PL96319352 A PL 96319352A PL 31935296 A PL31935296 A PL 31935296A PL 319352 A1 PL319352 A1 PL 319352A1
Authority
PL
Poland
Prior art keywords
halogenoethyl
anticarcinogenic
distamycin
bis
group substituted
Prior art date
Application number
PL96319352A
Inventor
Paolo Cozzi
Italo Beria
Laura Capolongo
Cristina Franzetti
Original Assignee
Pharmacia & Upjohn Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Spa filed Critical Pharmacia & Upjohn Spa
Publication of PL319352A1 publication Critical patent/PL319352A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
PL96319352A 1995-07-21 1996-06-19 Bis-(2-halogenoethyl) aminophenyl group substituted derivatives of distamycin as anticarcinogenic and antiviral drugs PL319352A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9514993.6A GB9514993D0 (en) 1995-07-21 1995-07-21 Site specific phenyl nitrogen mustards
PCT/EP1996/002659 WO1997003957A1 (en) 1995-07-21 1996-06-19 Bis-(2-haloethyl)aminophenyl substituted distamycin derivatives as antitumor and antiviral agents

Publications (1)

Publication Number Publication Date
PL319352A1 true PL319352A1 (en) 1997-08-04

Family

ID=10778062

Family Applications (1)

Application Number Title Priority Date Filing Date
PL96319352A PL319352A1 (en) 1995-07-21 1996-06-19 Bis-(2-halogenoethyl) aminophenyl group substituted derivatives of distamycin as anticarcinogenic and antiviral drugs

Country Status (18)

Country Link
EP (1) EP0787126A1 (en)
JP (1) JPH10506410A (en)
KR (1) KR970706251A (en)
CN (1) CN1159183A (en)
AR (1) AR003456A1 (en)
AU (1) AU6357996A (en)
BR (1) BR9606528A (en)
CA (1) CA2199635A1 (en)
EA (1) EA000033B1 (en)
GB (1) GB9514993D0 (en)
HU (1) HUP9702393A3 (en)
IL (1) IL120342A0 (en)
MX (1) MX9701949A (en)
NO (1) NO971142D0 (en)
PL (1) PL319352A1 (en)
TW (1) TW367325B (en)
WO (1) WO1997003957A1 (en)
ZA (1) ZA965028B (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998037066A1 (en) 1996-02-26 1998-08-27 California Institute Of Technology Improved polyamides for binding in the minor groove of double stranded dna
US6635417B1 (en) 1996-07-31 2003-10-21 California Institute Of Technology Complex formation between DSDNA and oligomer of cyclic heterocycles
US5998140A (en) 1996-07-31 1999-12-07 The Scripps Research Institute Complex formation between dsDNA and oligomer of cyclic heterocycles
GB9623522D0 (en) * 1996-11-11 1997-01-08 Pharmacia & Upjohn Spa Benzoheterocycle distamycin derivatives process for preparing them and their use as antitumour and antiviral agents
GB9816652D0 (en) * 1998-07-30 1998-09-30 Pharmacia & Upjohn Spa Sulfurated distamycin derivatives process for preparing them and their use as antitumor agents
GB9907414D0 (en) 1999-03-31 1999-05-26 Cancer Res Campaign Tech Improvements relating to prodrugs
US6559125B1 (en) 2000-01-28 2003-05-06 California Institute Of Technology Polyamide-alkylator conjugates and related products and method
WO2002101007A2 (en) 2001-06-13 2002-12-19 Genesoft Pharmaceuticals, Inc Antipathogenic benzamide compounds
US7498349B2 (en) 2002-08-02 2009-03-03 Genesoft Pharmaceuticals, Inc. Biaryl compounds having anti-infective activity
EP1562931A2 (en) 2002-10-25 2005-08-17 Genesoft Pharmaceuticals, Inc. Anti-infective biaryl compounds
EP1587529A4 (en) 2002-12-10 2009-08-12 Oscient Pharmaceuticals Corp Antibacterial compounds having a (pyrrole carboxamide)-(benzamide)-(imidazole carboxamide) motif
EP2792355A1 (en) 2013-04-17 2014-10-22 Albert-Ludwigs-Universität Freiburg Compounds for use as bromodomain inhibitors
CN115414356A (en) * 2022-09-27 2022-12-02 广西科技大学 Application of indenopyrrole derivatives in preparation of antitumor pharmaceutical composition

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8612218D0 (en) * 1986-05-20 1986-06-25 Erba Farmitalia Site specific alkylating agents

Also Published As

Publication number Publication date
NO971142L (en) 1997-03-12
EP0787126A1 (en) 1997-08-06
EA000033B1 (en) 1998-02-26
HUP9702393A2 (en) 1998-04-28
EA199700046A1 (en) 1997-12-30
GB9514993D0 (en) 1995-09-20
BR9606528A (en) 1997-12-23
ZA965028B (en) 1997-01-23
CA2199635A1 (en) 1997-02-06
WO1997003957A1 (en) 1997-02-06
AR003456A1 (en) 1998-08-05
MX9701949A (en) 1997-06-28
JPH10506410A (en) 1998-06-23
AU6357996A (en) 1997-02-18
IL120342A0 (en) 1997-06-10
TW367325B (en) 1999-08-21
CN1159183A (en) 1997-09-10
HUP9702393A3 (en) 1998-05-28
KR970706251A (en) 1997-11-03
NO971142D0 (en) 1997-03-12

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