IL120073A - Substituted 9-amino camptothecin compounds their preparation and pharmaceutical compositions containing them - Google Patents
Substituted 9-amino camptothecin compounds their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL120073A IL120073A IL12007394A IL12007394A IL120073A IL 120073 A IL120073 A IL 120073A IL 12007394 A IL12007394 A IL 12007394A IL 12007394 A IL12007394 A IL 12007394A IL 120073 A IL120073 A IL 120073A
- Authority
- IL
- Israel
- Prior art keywords
- formula
- compound
- chem
- amino camptothecin
- substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F23—COMBUSTION APPARATUS; COMBUSTION PROCESSES
- F23C—METHODS OR APPARATUS FOR COMBUSTION USING FLUID FUEL OR SOLID FUEL SUSPENDED IN A CARRIER GAS OR AIR
- F23C5/00—Disposition of burners with respect to the combustion chamber or to one another; Mounting of burners in combustion apparatus
- F23C5/02—Structural details of mounting
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL12007394A IL120073A (en) | 1993-09-28 | 1994-09-26 | Substituted 9-amino camptothecin compounds their preparation and pharmaceutical compositions containing them |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB939319944A GB9319944D0 (en) | 1993-09-28 | 1993-09-28 | Process for the preparation of 9-amino camptothecin |
IL11106694A IL111066A (en) | 1993-09-28 | 1994-09-26 | Process for the preparation of 9-amino camptothecin novel substituted 9-nitrocamptothecin derivatives thereof their preparation and pharmaceutical compositions containing them |
IL12007394A IL120073A (en) | 1993-09-28 | 1994-09-26 | Substituted 9-amino camptothecin compounds their preparation and pharmaceutical compositions containing them |
Publications (1)
Publication Number | Publication Date |
---|---|
IL120073A true IL120073A (en) | 1999-07-14 |
Family
ID=10742611
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL12007394A IL120073A (en) | 1993-09-28 | 1994-09-26 | Substituted 9-amino camptothecin compounds their preparation and pharmaceutical compositions containing them |
IL11106694A IL111066A (en) | 1993-09-28 | 1994-09-26 | Process for the preparation of 9-amino camptothecin novel substituted 9-nitrocamptothecin derivatives thereof their preparation and pharmaceutical compositions containing them |
IL12007397A IL120073A0 (en) | 1993-09-28 | 1997-01-24 | Substituted 9-amino camptothecin compounds their preparation and pharmaceutical compositions containing them |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL11106694A IL111066A (en) | 1993-09-28 | 1994-09-26 | Process for the preparation of 9-amino camptothecin novel substituted 9-nitrocamptothecin derivatives thereof their preparation and pharmaceutical compositions containing them |
IL12007397A IL120073A0 (en) | 1993-09-28 | 1997-01-24 | Substituted 9-amino camptothecin compounds their preparation and pharmaceutical compositions containing them |
Country Status (21)
Country | Link |
---|---|
US (2) | US5614628A (zh) |
EP (2) | EP0982307B1 (zh) |
JP (3) | JP3754068B2 (zh) |
KR (1) | KR950704323A (zh) |
CN (2) | CN1046283C (zh) |
AT (2) | ATE229022T1 (zh) |
AU (1) | AU676089B2 (zh) |
CA (1) | CA2150382C (zh) |
DE (2) | DE69422795T2 (zh) |
DK (2) | DK0670839T3 (zh) |
ES (2) | ES2144059T3 (zh) |
FI (1) | FI952549A (zh) |
GB (1) | GB9319944D0 (zh) |
GR (1) | GR3033197T3 (zh) |
HU (1) | HUT71267A (zh) |
IL (3) | IL120073A (zh) |
MY (1) | MY131618A (zh) |
PT (2) | PT982307E (zh) |
RU (1) | RU2137774C1 (zh) |
WO (1) | WO1995009169A1 (zh) |
ZA (1) | ZA947522B (zh) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9319944D0 (en) * | 1993-09-28 | 1993-11-17 | Erba Carlo Spa | Process for the preparation of 9-amino camptothecin |
GB9410388D0 (en) * | 1994-05-24 | 1994-07-13 | Erba Carlo Spa | Method for the preparation of 9-amino camptothecin |
US6504029B1 (en) * | 1995-04-10 | 2003-01-07 | Daiichi Pharmaceutical Co., Ltd. | Condensed-hexacyclic compounds and a process therefor |
GB9510716D0 (en) * | 1995-05-26 | 1995-07-19 | Pharmacia Spa | Substituted camptothecin derivatives and process for their preparation |
GB9600438D0 (en) * | 1996-01-10 | 1996-03-13 | Pharmacia Spa | Hexacyclic camptothecin analogues, and process for preparing them |
US5731316A (en) * | 1996-01-30 | 1998-03-24 | The Stehlin Foundation For Cancer Research | Derivatives of camptothecin and methods of treating cancer using these derivatives |
GB9601779D0 (en) * | 1996-01-30 | 1996-04-03 | Pharmacia Spa | 9, 10 Disubstituted camptothecin derivatives |
US6395541B1 (en) | 1996-05-23 | 2002-05-28 | The Rockefeller University | Methods for the identification of compounds capable of inhibiting HIV-1 viral replication employing murine cell lines expressing human topoisomerase I |
GB9702807D0 (en) | 1997-02-12 | 1997-04-02 | Pharmacia & Upjohn Spa | Alkynyl-substituted camptothecins and process for their preparation |
GB9715821D0 (en) * | 1997-07-25 | 1997-10-01 | Pharmacia & Upjohn Spa | Amidino-camptothecin derivatives |
US5922877A (en) * | 1997-08-05 | 1999-07-13 | The Stehlin Foundation For Cancer Research | Methods of preparing and purifying 9-nitro-20-camptothecin |
USRE38408E1 (en) | 1997-08-05 | 2004-01-27 | The Stehlin Foundation For Cancer Research | Methods of preparing and purifying 9-nitro-20-camptothecin |
WO2001024763A2 (en) | 1999-10-01 | 2001-04-12 | Immunogen, Inc. | Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents |
US7049322B2 (en) * | 2002-02-21 | 2006-05-23 | Supergen, Inc. | Compositions and formulations of 9-nitrocamptothecin polymorphs and methods of use therefor |
CN100334089C (zh) * | 2004-07-21 | 2007-08-29 | 王洋 | 一种9-硝基喜树碱的生产方法 |
US20060135546A1 (en) * | 2004-12-16 | 2006-06-22 | Jagadevappa Basavaraja | Methods for the purification of 20(S)- camptothecin |
CN1312155C (zh) * | 2005-01-21 | 2007-04-25 | 华东理工大学 | 一种分离纯化9-硝基喜树碱的方法 |
CN102481438B (zh) | 2009-06-26 | 2013-09-18 | 塔里斯生物医药公司 | 可植入药物递送装置及制造所述装置的方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9316352D0 (en) * | 1993-08-06 | 1993-09-22 | Erba Carlo Spa | Process for the preparation of 9-amino camptothecin |
GB9319944D0 (en) * | 1993-09-28 | 1993-11-17 | Erba Carlo Spa | Process for the preparation of 9-amino camptothecin |
GB9402934D0 (en) * | 1994-02-16 | 1994-04-06 | Erba Carlo Spa | Camptothecin derivatives and process for their preparation |
-
1993
- 1993-09-28 GB GB939319944A patent/GB9319944D0/en active Pending
-
1994
- 1994-09-15 DE DE69422795T patent/DE69422795T2/de not_active Expired - Fee Related
- 1994-09-15 JP JP51008495A patent/JP3754068B2/ja not_active Expired - Fee Related
- 1994-09-15 PT PT99202203T patent/PT982307E/pt unknown
- 1994-09-15 DK DK94927618T patent/DK0670839T3/da active
- 1994-09-15 CA CA002150382A patent/CA2150382C/en not_active Expired - Fee Related
- 1994-09-15 ES ES94927618T patent/ES2144059T3/es not_active Expired - Lifetime
- 1994-09-15 HU HU9501898A patent/HUT71267A/hu unknown
- 1994-09-15 EP EP99202203A patent/EP0982307B1/en not_active Expired - Lifetime
- 1994-09-15 PT PT94927618T patent/PT670839E/pt unknown
- 1994-09-15 RU RU95112485A patent/RU2137774C1/ru active
- 1994-09-15 DK DK99202203T patent/DK0982307T3/da active
- 1994-09-15 WO PCT/EP1994/003098 patent/WO1995009169A1/en active IP Right Grant
- 1994-09-15 AT AT99202203T patent/ATE229022T1/de not_active IP Right Cessation
- 1994-09-15 AT AT94927618T patent/ATE189221T1/de not_active IP Right Cessation
- 1994-09-15 EP EP94927618A patent/EP0670839B1/en not_active Expired - Lifetime
- 1994-09-15 DE DE69431856T patent/DE69431856T2/de not_active Expired - Fee Related
- 1994-09-15 AU AU76969/94A patent/AU676089B2/en not_active Ceased
- 1994-09-15 ES ES99202203T patent/ES2189345T3/es not_active Expired - Lifetime
- 1994-09-15 KR KR1019950702120A patent/KR950704323A/ko not_active Application Discontinuation
- 1994-09-15 CN CN94190731A patent/CN1046283C/zh not_active Expired - Fee Related
- 1994-09-26 IL IL12007394A patent/IL120073A/xx not_active IP Right Cessation
- 1994-09-26 IL IL11106694A patent/IL111066A/xx not_active IP Right Cessation
- 1994-09-27 ZA ZA947522A patent/ZA947522B/xx unknown
- 1994-09-28 US US08/313,906 patent/US5614628A/en not_active Expired - Fee Related
- 1994-09-28 MY MYPI94002582A patent/MY131618A/en unknown
-
1995
- 1995-05-24 FI FI952549A patent/FI952549A/fi unknown
-
1996
- 1996-12-31 US US08/775,605 patent/US5916897A/en not_active Expired - Fee Related
-
1997
- 1997-01-24 IL IL12007397A patent/IL120073A0/xx unknown
-
1999
- 1999-01-06 CN CN99100920A patent/CN1273974A/zh active Pending
-
2000
- 2000-04-12 GR GR20000400891T patent/GR3033197T3/el not_active IP Right Cessation
-
2004
- 2004-07-14 JP JP2004206841A patent/JP2005036003A/ja not_active Withdrawn
- 2004-07-14 JP JP2004206842A patent/JP2005036004A/ja not_active Withdrawn
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL120073A (en) | Substituted 9-amino camptothecin compounds their preparation and pharmaceutical compositions containing them | |
CA2059305A1 (en) | Hexa-cyclic compound | |
NZ306664A (en) | Intermediates of camptothecin (CPT-11) or mappicine and their manufacture | |
NZ227877A (en) | Anthracycline glycosides and pharmaceutical compositions; process of preparation | |
CA2011448A1 (en) | 6-amino-6-desoxyfumagillols, production and use thereof | |
CA2197467A1 (en) | Method for the preparation of taxol and its derivatives | |
HUT49887A (en) | Process for producing new cefem compounds | |
ATE63921T1 (de) | 6-amino-anthracycline, verfahren zu ihrer herstellung und ihre verwendung. | |
IL110553A (en) | Process for the preparation of 9-amino camptothecin from the 12-nitro derivative, pharmaceutical compositions containing it and certain intermediates | |
EG20562A (en) | Process for preparing glutaramide derivatives | |
ES8609250A1 (es) | Un procedimiento para la preparacion de nuevos derivados de ftalimida. | |
JPS5718641A (en) | Preparation of quinone | |
JPS5610150A (en) | Preparation of nitrotoluene derivative | |
JPS5610149A (en) | Preparation of nitrotoluene derivative | |
JPS57200340A (en) | Process for selective n-substitution of aromatic aminohydroxy compound | |
CA2327714A1 (en) | Preparation of 4,4-dimethyl-5.alpha.-cholesta-8,14,24-triene-3.beta.-o1 and novel intermediate compounds | |
EP0191399A3 (en) | Benzûa¨anthraquinone compounds, a microbial process for their preparation and their preparation and their use as medicaments | |
CA2362632A1 (en) | R-substituted-2- or 3-aminomethyl-4-amino-3,4-dihydro-2h-1,4-benzoxazines as intermediates for producing analgesic agents | |
JPS6413059A (en) | Gamma-hetero-beta-hydroxyamide derivative and production thereof | |
CA2141456A1 (en) | A process for the preparation of (-)-eserethole from mixtures of (-) and (+)-eserethole | |
JPS57145834A (en) | Novel cyclohexane derivative | |
TH2513EX (th) | การปรับปรุงในเรื่องอนุพันธ์เบนโซไธเอนิล ไกลซิลเซฟาโลสโพรินหรืออื่น ๆ ที่เกี่ยวข้องกัน | |
JPS646275A (en) | Mitomycin derivative | |
JPS649980A (en) | 8-aminocarsalam derivative |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB | Patent renewed | ||
KB | Patent renewed | ||
KB | Patent renewed | ||
MM9K | Patent not in force due to non-payment of renewal fees |