ES8609250A1 - Un procedimiento para la preparacion de nuevos derivados de ftalimida. - Google Patents

Un procedimiento para la preparacion de nuevos derivados de ftalimida.

Info

Publication number
ES8609250A1
ES8609250A1 ES545820A ES545820A ES8609250A1 ES 8609250 A1 ES8609250 A1 ES 8609250A1 ES 545820 A ES545820 A ES 545820A ES 545820 A ES545820 A ES 545820A ES 8609250 A1 ES8609250 A1 ES 8609250A1
Authority
ES
Spain
Prior art keywords
preparing
compositions containing
phthalimide derivatives
compounds
nitrooxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES545820A
Other languages
English (en)
Other versions
ES545820A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Publication of ES8609250A1 publication Critical patent/ES8609250A1/es
Publication of ES545820A0 publication Critical patent/ES545820A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE FTALIMIDA Y DE SUS SALES FISIOLOGICAMENTE COMPATIBLES, DE FORMULA (I), EN LA QUE R1 REPRESENTA HIDROGENO O EL GRUPO NITRO; Y A Y R2 PUEDEN SER VARIOS TIPOS DE RADICALES. CONSISTE EN LA REACCION DE NITRACION DE UN COMPUESTO DE FORMULA (II), EN LA QUE AK REPRESENTA ALQUILENO C1-6 SIN SUSTITUIR O CON 1 O 2 SUSTITUYENTES HIDROXI, Y R2K PUEDE SER UNO DE VARIOS TIPOS DE RADICALES. LA NITRACION SE EFECTUA POR TRATAMIENTO CON ACIDO NITRICO FUMANTE, CON MEZCLA DE ACIDO NITRICO FUMANTE Y ANHIDRIDO ACETICO, O CON ACIDOS NITRICO Y SULFURICO CONCENTRADOS, A UNA TEMPERATURA COMPRENDIDA ENTRE C30JC Y LA AMBIENTE. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO DE LA ANGINA DE PECHO.
ES545820A 1984-07-31 1985-07-31 Un procedimiento para la preparacion de nuevos derivados de ftalimida. Expired ES8609250A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP16039984A JPS6137766A (ja) 1984-07-31 1984-07-31 フタルイミド誘導体およびその製造法

Publications (2)

Publication Number Publication Date
ES8609250A1 true ES8609250A1 (es) 1986-07-16
ES545820A0 ES545820A0 (es) 1986-07-16

Family

ID=15714102

Family Applications (1)

Application Number Title Priority Date Filing Date
ES545820A Expired ES8609250A1 (es) 1984-07-31 1985-07-31 Un procedimiento para la preparacion de nuevos derivados de ftalimida.

Country Status (3)

Country Link
EP (1) EP0171977A1 (es)
JP (1) JPS6137766A (es)
ES (1) ES8609250A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1244472B (it) * 1990-12-14 1994-07-15 Italfarmaco Spa Benzossazinoni e benzotiazinoni ad attivita' cardiovascolare
IT1245351B (it) * 1991-03-19 1994-09-20 Italfarmaco Spa Isoindoli ad attivita' cardiovascolare
CH685700A5 (fr) * 1993-03-16 1995-09-15 Cermol Sa Esters nitriques de 1,2-benzo-isothiazolyl-3(2H)one-1,1-dioxyde, procédé de préparation de ces esters et médicaments contenant ces esters.
BRPI0705396B1 (pt) * 2007-12-12 2021-10-05 Universidade Estadual De Campinas - Unicamp Compostos derivados ftalimídicos

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3984435A (en) * 1970-12-23 1976-10-05 Mitsubishi Chemical Industries Ltd. Herbicidal N-substituted-Δ1 -tetrahydrophthalimide

Also Published As

Publication number Publication date
EP0171977A1 (en) 1986-02-19
JPS6137766A (ja) 1986-02-22
ES545820A0 (es) 1986-07-16

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