GR3033197T3 - Process for the preparation of 9-amino camptothecin. - Google Patents

Process for the preparation of 9-amino camptothecin.

Info

Publication number
GR3033197T3
GR3033197T3 GR20000400891T GR20000400891T GR3033197T3 GR 3033197 T3 GR3033197 T3 GR 3033197T3 GR 20000400891 T GR20000400891 T GR 20000400891T GR 20000400891 T GR20000400891 T GR 20000400891T GR 3033197 T3 GR3033197 T3 GR 3033197T3
Authority
GR
Greece
Prior art keywords
formula
compound
chem
group
amino camptothecin
Prior art date
Application number
GR20000400891T
Other languages
English (en)
Inventor
Walter Cabri
Ilaria Candiani
Franco Zarini
Angelo Bedeschi
Sergio Penco
Original Assignee
Pharmacia Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Spa filed Critical Pharmacia Spa
Publication of GR3033197T3 publication Critical patent/GR3033197T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F23—COMBUSTION APPARATUS; COMBUSTION PROCESSES
    • F23C—METHODS OR APPARATUS FOR COMBUSTION USING FLUID FUEL OR SOLID FUEL SUSPENDED IN  A CARRIER GAS OR AIR 
    • F23C5/00—Disposition of burners with respect to the combustion chamber or to one another; Mounting of burners in combustion apparatus
    • F23C5/02—Structural details of mounting

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mechanical Engineering (AREA)
  • Combustion & Propulsion (AREA)
  • General Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
GR20000400891T 1993-09-28 2000-04-12 Process for the preparation of 9-amino camptothecin. GR3033197T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB939319944A GB9319944D0 (en) 1993-09-28 1993-09-28 Process for the preparation of 9-amino camptothecin
PCT/EP1994/003098 WO1995009169A1 (en) 1993-09-28 1994-09-15 Process for the preparation of 9-amino camptothecin

Publications (1)

Publication Number Publication Date
GR3033197T3 true GR3033197T3 (en) 2000-08-31

Family

ID=10742611

Family Applications (1)

Application Number Title Priority Date Filing Date
GR20000400891T GR3033197T3 (en) 1993-09-28 2000-04-12 Process for the preparation of 9-amino camptothecin.

Country Status (21)

Country Link
US (2) US5614628A (el)
EP (2) EP0982307B1 (el)
JP (3) JP3754068B2 (el)
KR (1) KR950704323A (el)
CN (2) CN1046283C (el)
AT (2) ATE229022T1 (el)
AU (1) AU676089B2 (el)
CA (1) CA2150382C (el)
DE (2) DE69422795T2 (el)
DK (2) DK0982307T3 (el)
ES (2) ES2189345T3 (el)
FI (1) FI952549A (el)
GB (1) GB9319944D0 (el)
GR (1) GR3033197T3 (el)
HU (1) HUT71267A (el)
IL (3) IL111066A (el)
MY (1) MY131618A (el)
PT (2) PT982307E (el)
RU (1) RU2137774C1 (el)
WO (1) WO1995009169A1 (el)
ZA (1) ZA947522B (el)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9319944D0 (en) * 1993-09-28 1993-11-17 Erba Carlo Spa Process for the preparation of 9-amino camptothecin
GB9410388D0 (en) * 1994-05-24 1994-07-13 Erba Carlo Spa Method for the preparation of 9-amino camptothecin
US6504029B1 (en) * 1995-04-10 2003-01-07 Daiichi Pharmaceutical Co., Ltd. Condensed-hexacyclic compounds and a process therefor
GB9510716D0 (en) * 1995-05-26 1995-07-19 Pharmacia Spa Substituted camptothecin derivatives and process for their preparation
GB9600438D0 (en) * 1996-01-10 1996-03-13 Pharmacia Spa Hexacyclic camptothecin analogues, and process for preparing them
GB9601779D0 (en) * 1996-01-30 1996-04-03 Pharmacia Spa 9, 10 Disubstituted camptothecin derivatives
US5731316A (en) * 1996-01-30 1998-03-24 The Stehlin Foundation For Cancer Research Derivatives of camptothecin and methods of treating cancer using these derivatives
US6395541B1 (en) 1996-05-23 2002-05-28 The Rockefeller University Methods for the identification of compounds capable of inhibiting HIV-1 viral replication employing murine cell lines expressing human topoisomerase I
GB9702807D0 (en) 1997-02-12 1997-04-02 Pharmacia & Upjohn Spa Alkynyl-substituted camptothecins and process for their preparation
GB9715821D0 (en) * 1997-07-25 1997-10-01 Pharmacia & Upjohn Spa Amidino-camptothecin derivatives
US5922877A (en) * 1997-08-05 1999-07-13 The Stehlin Foundation For Cancer Research Methods of preparing and purifying 9-nitro-20-camptothecin
USRE38408E1 (en) 1997-08-05 2004-01-27 The Stehlin Foundation For Cancer Research Methods of preparing and purifying 9-nitro-20-camptothecin
EP1229934B1 (en) 1999-10-01 2014-03-05 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
US7049322B2 (en) * 2002-02-21 2006-05-23 Supergen, Inc. Compositions and formulations of 9-nitrocamptothecin polymorphs and methods of use therefor
CN100334089C (zh) * 2004-07-21 2007-08-29 王洋 一种9－硝基喜树碱的生产方法
US20060135546A1 (en) * 2004-12-16 2006-06-22 Jagadevappa Basavaraja Methods for the purification of 20(S)- camptothecin
CN1312155C (zh) * 2005-01-21 2007-04-25 华东理工大学 一种分离纯化9－硝基喜树碱的方法
SG177360A1 (en) 2009-06-26 2012-02-28 Taris Biomedical Inc Implantable drug delivery devices and methods of making the same

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9316352D0 (en) * 1993-08-06 1993-09-22 Erba Carlo Spa Process for the preparation of 9-amino camptothecin
GB9319944D0 (en) * 1993-09-28 1993-11-17 Erba Carlo Spa Process for the preparation of 9-amino camptothecin
GB9402934D0 (en) * 1994-02-16 1994-04-06 Erba Carlo Spa Camptothecin derivatives and process for their preparation

Also Published As

Publication number Publication date
AU676089B2 (en) 1997-02-27
FI952549A0 (fi) 1995-05-24
JP3754068B2 (ja) 2006-03-08
HUT71267A (en) 1995-11-28
DE69431856D1 (de) 2003-01-16
DK0982307T3 (da) 2003-03-24
EP0670839B1 (en) 2000-01-26
RU95112485A (ru) 1997-04-20
CN1046283C (zh) 1999-11-10
ATE229022T1 (de) 2002-12-15
ATE189221T1 (de) 2000-02-15
PT982307E (pt) 2003-04-30
EP0982307B1 (en) 2002-12-04
CA2150382A1 (en) 1995-04-06
JPH08506834A (ja) 1996-07-23
HU9501898D0 (en) 1995-08-28
PT670839E (pt) 2000-05-31
WO1995009169A1 (en) 1995-04-06
JP2005036003A (ja) 2005-02-10
IL111066A (en) 1999-12-31
DE69422795D1 (de) 2000-03-02
ES2189345T3 (es) 2003-07-01
JP2005036004A (ja) 2005-02-10
DE69422795T2 (de) 2000-07-20
DK0670839T3 (da) 2002-12-23
DE69431856T2 (de) 2003-08-21
EP0670839A1 (en) 1995-09-13
FI952549A (fi) 1995-07-21
CN1115181A (zh) 1996-01-17
ZA947522B (en) 1995-05-29
IL120073A0 (en) 1997-04-15
MY131618A (en) 2007-08-30
RU2137774C1 (ru) 1999-09-20
IL120073A (en) 1999-07-14
EP0982307A2 (en) 2000-03-01
KR950704323A (ko) 1995-11-17
US5614628A (en) 1997-03-25
EP0982307A3 (en) 2000-07-26
AU7696994A (en) 1995-04-18
US5916897A (en) 1999-06-29
CN1273974A (zh) 2000-11-22
ES2144059T3 (es) 2000-06-01
IL111066A0 (en) 1994-12-29
CA2150382C (en) 2006-12-05
GB9319944D0 (en) 1993-11-17

Similar Documents

Publication Publication Date Title
GR3033197T3 (en) Process for the preparation of 9-amino camptothecin.
CA2059305A1 (en) Hexa-cyclic compound
AU1834988A (en) Hexa-cyclic compound
CA2273789A1 (en) Process to prepare tolterodine
CA2273030A1 (en) Process for preparing .beta.-hydroxyalkylamides
CA2298548A1 (en) Method for producing 2-(3-pyrazolyl-oxymethylene) nitrobenzenes
GB9207380D0 (en) Compounds
CA2101178A1 (en) New polycyclic polyamides as precursors for energetic polycyclic polynitramine oxidizers
WO2001002407A3 (en) Taxane derivatives and processes for the preparation thereof
CA2197467A1 (en) Method for the preparation of taxol and its derivatives
ATE63921T1 (de) 6-amino-anthracycline, verfahren zu ihrer herstellung und ihre verwendung.
HUT49887A (en) Process for producing new cefem compounds
CA2145514A1 (en) Process for the preparation of 9-amino camptothecin
JPS5610149A (en) Preparation of nitrotoluene derivative
JPS5610150A (en) Preparation of nitrotoluene derivative
JPS5718641A (en) Preparation of quinone
IE822918L (en) N-phenyl-pyridinamines and pyrido-£1,4| benzodiazepines
IE881598L (en) Process for preparing aromatic nitriles
CA2362632A1 (en) R-substituted-2- or 3-aminomethyl-4-amino-3,4-dihydro-2h-1,4-benzoxazines as intermediates for producing analgesic agents
JPS57200340A (en) Process for selective n-substitution of aromatic aminohydroxy compound
CA2327714A1 (en) Preparation of 4,4-dimethyl-5.alpha.-cholesta-8,14,24-triene-3.beta.-o1 and novel intermediate compounds
CA2106415A1 (en) Process for the preparation of endo/exo-8-n,n-dialkylamino-exo-tricyclo[5.2.1.0 2,6]decane
EP1304328A4 (en) METHOD FOR PRODUCING A BENZOFURANE DERIVATIVE
ES2019043A6 (es) Procedimiento de preparacion de s-pancopride.
ES2019042A6 (es) Procedimiento de preparacion de r-pancopride.

Legal Events

Date Code Title Description
ML Lapse due to non-payment of fees