IE822918L - N-phenyl-pyridinamines and pyrido-£1,4| benzodiazepines - Google Patents

N-phenyl-pyridinamines and pyrido-£1,4| benzodiazepines

Info

Publication number
IE822918L
IE822918L IE822918A IE291882A IE822918L IE 822918 L IE822918 L IE 822918L IE 822918 A IE822918 A IE 822918A IE 291882 A IE291882 A IE 291882A IE 822918 L IE822918 L IE 822918L
Authority
IE
Ireland
Prior art keywords
benzodiazepines
pyrido
pyridinamines
phenyl
aroylamino
Prior art date
Application number
IE822918A
Other versions
IE54618B1 (en
Original Assignee
Robins Co Inc A H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robins Co Inc A H filed Critical Robins Co Inc A H
Publication of IE822918L publication Critical patent/IE822918L/en
Publication of IE54618B1 publication Critical patent/IE54618B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Nitro, amino and aroylamino-N-phenylpyridinamines as chemical intermediates and/or having antidepressant activity having the formula <IMAGE> wherein R3 is nitro, amino or aroylamino, and Q is hydrogen, -NR1R2 or halogen are disclosed in a process for preparing pyrido[1,4]benzodiazepines. [US4558132A]
IE2918/82A 1982-07-02 1982-12-08 Nitro, amino and aroylamino-n-phenylpyridinamines in a process for preparing pyrido (1,4) benzodiazepines IE54618B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/394,551 US4558132A (en) 1982-07-02 1982-07-02 Nitro, amino and aroylamino-N-phenylpyridinamines in a process for preparing pyrido[1,4]benzodiazepines

Publications (2)

Publication Number Publication Date
IE822918L true IE822918L (en) 1984-01-02
IE54618B1 IE54618B1 (en) 1989-12-20

Family

ID=23559432

Family Applications (1)

Application Number Title Priority Date Filing Date
IE2918/82A IE54618B1 (en) 1982-07-02 1982-12-08 Nitro, amino and aroylamino-n-phenylpyridinamines in a process for preparing pyrido (1,4) benzodiazepines

Country Status (20)

Country Link
US (1) US4558132A (en)
EP (1) EP0099614A3 (en)
JP (1) JPS597166A (en)
KR (1) KR880001282B1 (en)
AU (1) AU550950B2 (en)
CA (1) CA1198424A (en)
DK (1) DK547782A (en)
ES (2) ES8406441A1 (en)
FI (1) FI78076C (en)
GR (1) GR77822B (en)
HU (2) HU191837B (en)
IE (1) IE54618B1 (en)
IL (1) IL67508A (en)
IN (1) IN156481B (en)
NO (1) NO158062C (en)
NZ (1) NZ202800A (en)
PH (1) PH21401A (en)
PL (4) PL141485B1 (en)
PT (1) PT76093B (en)
ZA (1) ZA829155B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3409237A1 (en) * 1984-03-14 1985-09-19 Dr. Karl Thomae Gmbh, 7950 Biberach CONDENSED DIAZEPINONE, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS
DE3626095A1 (en) * 1986-07-31 1988-02-11 Thomae Gmbh Dr K NEW SUBSTITUTED PYRIDO (2,3-B) (1,4) BENZODIAZEPIN-6-ONE, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS
US4749788A (en) * 1987-04-13 1988-06-07 A. H. Robins Company, Incorporated Process for the preparation of aryl-pyrido(1,4) benzodiazepines

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2785172A (en) * 1953-06-17 1957-03-12 Searle & Co Dialkylaminoalkylphenetidinopyridine
GB907646A (en) * 1959-01-23 1962-10-10 Wander S A A Method of production of new derivatives of diazepin
FR8363M (en) * 1967-02-01 1971-02-15
GB1192995A (en) * 1967-04-12 1970-05-28 Egyt Gyogyszervegyeszeti Gyar Formimino Ethers
GB1268772A (en) * 1968-03-15 1972-03-29 Glaxo Lab Ltd NOVEL alpha-CARBOLINE DERIVATIVES, THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME
AT327200B (en) * 1972-09-06 1976-01-26 Degussa PROCESS FOR THE PREPARATION OF NEW AZA-10,11-DIHYDRO-5H-DIBENZO (B, E) - (1,4) DIAZEPINES AND THEIR SALTS
AT325052B (en) * 1972-12-07 1975-10-10 Degussa PROCESS FOR THE PREPARATION OF NEW 6-AZABENZO-1,5-DIAZEPINES AND THEIR SALT
DK209976A (en) * 1975-05-28 1976-11-29 Merck & Co Inc PROCEDURE FOR THE PREPARATION OF 3H-1,2,2-TRIAZOLE (4,5-B) PYRIDINES

Also Published As

Publication number Publication date
PL250097A1 (en) 1985-09-10
HU194175B (en) 1988-01-28
JPS597166A (en) 1984-01-14
PH21401A (en) 1987-10-15
AU9163382A (en) 1984-01-05
PL250096A1 (en) 1985-09-10
IL67508A (en) 1986-02-28
KR880001282B1 (en) 1988-07-18
FI78076C (en) 1989-06-12
NO158062B (en) 1988-03-28
IN156481B (en) 1985-08-10
FI824247A0 (en) 1982-12-10
PT76093A (en) 1983-02-01
HUT40420A (en) 1986-12-28
KR840002837A (en) 1984-07-21
AU550950B2 (en) 1986-04-10
IE54618B1 (en) 1989-12-20
EP0099614A3 (en) 1985-05-29
NZ202800A (en) 1987-07-31
PL241785A1 (en) 1985-02-27
ES518376A0 (en) 1984-08-01
PL250095A1 (en) 1985-09-10
GR77822B (en) 1984-09-25
FI78076B (en) 1989-02-28
HUT34477A (en) 1985-03-28
DK547782A (en) 1984-01-03
PT76093B (en) 1986-01-09
HU191837B (en) 1987-04-28
ES531221A0 (en) 1985-09-01
PL141485B1 (en) 1987-07-31
PL144138B1 (en) 1988-04-30
EP0099614A2 (en) 1984-02-01
FI824247L (en) 1984-01-03
CA1198424A (en) 1985-12-24
ES8507496A1 (en) 1985-09-01
ES8406441A1 (en) 1984-08-01
US4558132A (en) 1985-12-10
NO824115L (en) 1984-01-03
NO158062C (en) 1988-07-06
ZA829155B (en) 1983-09-28
PL143959B1 (en) 1988-03-31
PL144137B1 (en) 1988-04-30

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