CA2362632A1 - R-substituted-2- or 3-aminomethyl-4-amino-3,4-dihydro-2h-1,4-benzoxazines as intermediates for producing analgesic agents - Google Patents
R-substituted-2- or 3-aminomethyl-4-amino-3,4-dihydro-2h-1,4-benzoxazines as intermediates for producing analgesic agents Download PDFInfo
- Publication number
- CA2362632A1 CA2362632A1 CA002362632A CA2362632A CA2362632A1 CA 2362632 A1 CA2362632 A1 CA 2362632A1 CA 002362632 A CA002362632 A CA 002362632A CA 2362632 A CA2362632 A CA 2362632A CA 2362632 A1 CA2362632 A1 CA 2362632A1
- Authority
- CA
- Canada
- Prior art keywords
- benzoxazines
- aminomethyl
- intermediates
- amino
- dihydro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000730 antalgic agent Substances 0.000 title abstract 2
- 239000000543 intermediate Substances 0.000 title abstract 2
- AZLYGBBJAKAFBL-UHFFFAOYSA-N 3-(aminomethyl)-2,3-dihydro-1,4-benzoxazin-4-amine Chemical class C1=CC=C2N(N)C(CN)COC2=C1 AZLYGBBJAKAFBL-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Landscapes
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Disclosed are novel compounds of the formula:
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29190588A | 1988-12-29 | 1988-12-29 | |
| US291,905 | 1988-12-29 | ||
| US447,469 | 1989-12-07 | ||
| US07/447,469 US4939138A (en) | 1988-12-29 | 1989-12-07 | 2- and 3-aminomethyl-6-arylcarbonyl-2,3-dihydropyrrolo(1,2,3-DE)-1,4-benzoxazines |
| CA002006769A CA2006769C (en) | 1988-12-29 | 1989-12-28 | 2-and 3-aminomethyl-6-arylcarbonyl-2,3-dihydropyrrolo [1,2,3,-de] -1,4-benzoxazines useful as analgesic agents |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002006769A Division CA2006769C (en) | 1988-12-29 | 1989-12-28 | 2-and 3-aminomethyl-6-arylcarbonyl-2,3-dihydropyrrolo [1,2,3,-de] -1,4-benzoxazines useful as analgesic agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2362632A1 true CA2362632A1 (en) | 1990-06-29 |
| CA2362632C CA2362632C (en) | 2006-06-06 |
Family
ID=27168688
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002362632A Expired - Lifetime CA2362632C (en) | 1988-12-29 | 1989-12-28 | R-substituted-2- or 3-aminomethyl-4-amino-3,4-dihydro-2h-1,4-benzoxazines as intermediates for producing analgesic agents |
Country Status (1)
| Country | Link |
|---|---|
| CA (1) | CA2362632C (en) |
-
1989
- 1989-12-28 CA CA002362632A patent/CA2362632C/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA2362632C (en) | 2006-06-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKEX | Expiry |