IL117152A - Transformed benzenesulfonylureas and theories, processes for their preparation and use in the preparation of pharmaceutical preparations, and pharmaceutical preparations containing them - Google Patents
Transformed benzenesulfonylureas and theories, processes for their preparation and use in the preparation of pharmaceutical preparations, and pharmaceutical preparations containing themInfo
- Publication number
- IL117152A IL117152A IL11715296A IL11715296A IL117152A IL 117152 A IL117152 A IL 117152A IL 11715296 A IL11715296 A IL 11715296A IL 11715296 A IL11715296 A IL 11715296A IL 117152 A IL117152 A IL 117152A
- Authority
- IL
- Israel
- Prior art keywords
- carbon atoms
- sulfonylamino
- alkyl
- hydrogen
- methylaminothiocarbonyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C335/40—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of thiourea or isothiourea groups further bound to other hetero atoms
- C07C335/42—Sulfonylthioureas; Sulfonylisothioureas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
- C07C311/52—Y being a hetero atom
- C07C311/54—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea
- C07C311/57—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings
- C07C311/58—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings having nitrogen atoms of the sulfonylurea groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19505398A DE19505398A1 (de) | 1995-02-17 | 1995-02-17 | Substituierte Benzolsulfonylharnstoffe und -thioharnstoffe, Verfahren zu ihrer Herstellung und Verwendung pharmazeutischer Präparate auf Basis dieser Verbindungen sowie sie enthaltende Heilmittel |
| DE19522920A DE19522920A1 (de) | 1995-06-23 | 1995-06-23 | Substituierte Benzolsulfonylharnstoffe und -thioharnstoffe, Verfahren zu ihrer Herstellung und Verwendung pharmazeutischer Präparate auf Basis dieser Verbindungen sowie sie enthaltende Heilmittel |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL117152A0 IL117152A0 (en) | 1996-06-18 |
| IL117152A true IL117152A (en) | 2002-07-25 |
Family
ID=26012537
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL11715296A IL117152A (en) | 1995-02-17 | 1996-02-15 | Transformed benzenesulfonylureas and theories, processes for their preparation and use in the preparation of pharmaceutical preparations, and pharmaceutical preparations containing them |
Country Status (29)
| Country | Link |
|---|---|
| US (2) | US5880155A (ko) |
| EP (1) | EP0727417B1 (ko) |
| JP (1) | JP3905573B2 (ko) |
| KR (1) | KR100432259B1 (ko) |
| CN (1) | CN1060162C (ko) |
| AR (1) | AR002708A1 (ko) |
| AT (1) | ATE199541T1 (ko) |
| AU (1) | AU700254B2 (ko) |
| BR (1) | BR9600779A (ko) |
| CA (1) | CA2169696C (ko) |
| CZ (1) | CZ291793B6 (ko) |
| DE (1) | DE59606531D1 (ko) |
| DK (1) | DK0727417T3 (ko) |
| ES (1) | ES2155546T3 (ko) |
| FI (1) | FI120391B (ko) |
| GR (1) | GR3035710T3 (ko) |
| HR (1) | HRP960076B1 (ko) |
| HU (1) | HU226462B1 (ko) |
| IL (1) | IL117152A (ko) |
| MY (1) | MY115795A (ko) |
| NO (1) | NO305795B1 (ko) |
| NZ (1) | NZ280992A (ko) |
| PL (1) | PL181792B1 (ko) |
| PT (1) | PT727417E (ko) |
| RU (1) | RU2198872C2 (ko) |
| SI (1) | SI9600050B (ko) |
| SK (1) | SK282131B6 (ko) |
| TR (1) | TR199600117A2 (ko) |
| TW (1) | TW357141B (ko) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19546736A1 (de) * | 1995-12-14 | 1997-06-19 | Hoechst Ag | Substituierte Chromanylsulfonyl(thio)harnstoffe, Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung pharmazeutischer Präparate |
| TR199901816T2 (xx) * | 1997-01-29 | 1999-11-22 | Pfizer Inc | S�lfonil �re t�revleri, bunlar�n interl�kin-1 aktivitesinin kontrol�nde kullan�mlar�. |
| DE19832009A1 (de) | 1998-07-16 | 2000-01-20 | Hoechst Marion Roussel De Gmbh | 2,5-Substituierte Benzolsulfonylharnstoffe und -thioharnstoffe, Verfahren zu ihrer Herstellung, ihre Verwendung und sie enthaltende pharamazeutische Präparate |
| DE10129704A1 (de) * | 2001-06-22 | 2003-01-02 | Aventis Pharma Gmbh | Verwendung von Benzolsulfonyl(thio)harnstoffen in der Behandlung des septischen Schocks |
| ES2333979T3 (es) * | 2004-11-22 | 2010-03-03 | Eli Lilly And Company | Potenciadores de los receptores del glutamato. |
| CN104649945B (zh) * | 2015-02-05 | 2017-02-22 | 中国农业大学 | 一种磺酰脲类、磺酰胺基甲酸酯类化合物的制备方法 |
| WO2023020412A1 (zh) * | 2021-08-16 | 2023-02-23 | 中国科学院上海药物研究所 | 磺酰脲化合物、制备方法及其应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1198354B (de) * | 1963-09-25 | 1965-08-12 | Hoechst Ag | Verfahren zur Herstellung von Benzol-sulfonylharnstoffen |
| DE1185180B (de) * | 1963-10-19 | 1965-01-14 | Hoechst Ag | Verfahren zur Herstellung von Benzolsulfonylharnstoffen |
| BE754454A (fr) * | 1969-08-06 | 1971-02-05 | Bayer Ag | Nouveaux composes hypoglycemiques du type d'arylsulfonylurees et d'arylsulfonylsemicarbazides contenant des groupes carbonamide |
| DE2413514C3 (de) * | 1974-03-21 | 1982-03-04 | Hoechst Ag, 6000 Frankfurt | N-Acylaminoathylbenzolsulfonyl-N'-methylharnstoffe, Verfahren zu ihrer Herstellung und deren Verwendung |
| DK0612724T3 (da) * | 1993-02-23 | 1997-06-16 | Hoechst Ag | Substituerede benzensulfonylurinstoffer og -thiourinstoffer, fremgangsmåde til deres fremstilling og deres anvendelse som farmaceutika |
-
1995
- 1995-12-28 HU HU9503877A patent/HU226462B1/hu not_active IP Right Cessation
-
1996
- 1996-01-29 PL PL96312530A patent/PL181792B1/pl not_active IP Right Cessation
- 1996-02-12 TW TW085101696A patent/TW357141B/zh not_active IP Right Cessation
- 1996-02-12 DE DE59606531T patent/DE59606531D1/de not_active Expired - Lifetime
- 1996-02-12 AT AT96101977T patent/ATE199541T1/de active
- 1996-02-12 DK DK96101977T patent/DK0727417T3/da active
- 1996-02-12 ES ES96101977T patent/ES2155546T3/es not_active Expired - Lifetime
- 1996-02-12 EP EP96101977A patent/EP0727417B1/de not_active Expired - Lifetime
- 1996-02-12 PT PT96101977T patent/PT727417E/pt unknown
- 1996-02-14 CN CN96102017A patent/CN1060162C/zh not_active Expired - Fee Related
- 1996-02-14 CZ CZ1996435A patent/CZ291793B6/cs not_active IP Right Cessation
- 1996-02-15 US US08/602,018 patent/US5880155A/en not_active Expired - Lifetime
- 1996-02-15 IL IL11715296A patent/IL117152A/en not_active IP Right Cessation
- 1996-02-15 HR HR960076A patent/HRP960076B1/xx not_active IP Right Cessation
- 1996-02-15 TR TR96/00117A patent/TR199600117A2/xx unknown
- 1996-02-15 SK SK212-96A patent/SK282131B6/sk not_active IP Right Cessation
- 1996-02-15 AU AU45559/96A patent/AU700254B2/en not_active Ceased
- 1996-02-15 FI FI960688A patent/FI120391B/fi not_active IP Right Cessation
- 1996-02-15 AR ARP960101391A patent/AR002708A1/es unknown
- 1996-02-15 NZ NZ280992A patent/NZ280992A/en not_active IP Right Cessation
- 1996-02-16 SI SI9600050A patent/SI9600050B/sl not_active IP Right Cessation
- 1996-02-16 MY MYPI96000622A patent/MY115795A/en unknown
- 1996-02-16 RU RU96102852/04A patent/RU2198872C2/ru not_active IP Right Cessation
- 1996-02-16 NO NO960628A patent/NO305795B1/no not_active IP Right Cessation
- 1996-02-16 KR KR1019960003823A patent/KR100432259B1/ko not_active IP Right Cessation
- 1996-02-16 BR BR9600779A patent/BR9600779A/pt not_active IP Right Cessation
- 1996-02-16 CA CA002169696A patent/CA2169696C/en not_active Expired - Fee Related
- 1996-02-16 JP JP05263396A patent/JP3905573B2/ja not_active Expired - Fee Related
-
1998
- 1998-06-04 US US09/090,403 patent/US5977177A/en not_active Expired - Lifetime
-
2001
- 2001-04-06 GR GR20010400560T patent/GR3035710T3/el unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |