IL115016A - Benzothiophene derivatives for bone healing and fracture repair pharmaceutical compositions comprising same and uses thereof - Google Patents

Benzothiophene derivatives for bone healing and fracture repair pharmaceutical compositions comprising same and uses thereof

Info

Publication number
IL115016A
IL115016A IL11501695A IL11501695A IL115016A IL 115016 A IL115016 A IL 115016A IL 11501695 A IL11501695 A IL 11501695A IL 11501695 A IL11501695 A IL 11501695A IL 115016 A IL115016 A IL 115016A
Authority
IL
Israel
Prior art keywords
bone healing
fracture repair
pharmaceutical compositions
same
benzothiophene derivatives
Prior art date
Application number
IL11501695A
Other languages
English (en)
Other versions
IL115016A0 (en
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of IL115016A0 publication Critical patent/IL115016A0/xx
Publication of IL115016A publication Critical patent/IL115016A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Hydrogenated Pyridines (AREA)
  • Meat, Egg Or Seafood Products (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Materials For Medical Uses (AREA)
IL11501695A 1994-08-22 1995-08-21 Benzothiophene derivatives for bone healing and fracture repair pharmaceutical compositions comprising same and uses thereof IL115016A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/294,130 US5502074A (en) 1994-08-22 1994-08-22 Benzothiophenes for bone healing and fracture repair

Publications (2)

Publication Number Publication Date
IL115016A0 IL115016A0 (en) 1995-12-08
IL115016A true IL115016A (en) 1999-09-22

Family

ID=23132010

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11501695A IL115016A (en) 1994-08-22 1995-08-21 Benzothiophene derivatives for bone healing and fracture repair pharmaceutical compositions comprising same and uses thereof

Country Status (20)

Country Link
US (1) US5502074A (de)
EP (1) EP0769945B1 (de)
JP (1) JPH10504578A (de)
KR (1) KR970705385A (de)
AT (1) ATE240101T1 (de)
AU (1) AU701946B2 (de)
CA (1) CA2198012A1 (de)
CZ (1) CZ51997A3 (de)
DE (1) DE69530771T2 (de)
DK (1) DK0769945T3 (de)
ES (1) ES2197207T3 (de)
FI (1) FI970715A (de)
HU (1) HUT76855A (de)
IL (1) IL115016A (de)
MX (1) MX9701332A (de)
NO (1) NO970785L (de)
PH (1) PH31620A (de)
PT (1) PT769945E (de)
WO (1) WO1996005825A1 (de)
ZA (1) ZA956989B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5856340A (en) 1995-02-28 1999-01-05 Eli Lilly And Company Method of treating estrogen dependent cancers
US7005428B1 (en) 1998-06-11 2006-02-28 Endorecherche, Inc. Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors
US6465445B1 (en) 1998-06-11 2002-10-15 Endorecherche, Inc. Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors
AU5862199A (en) * 1998-09-11 2000-04-03 Michael Raschke Biologically active implants
DK1175433T3 (da) 1999-05-04 2005-09-19 Strakan Int Ltd Androgenglycosider og androgen aktivitet deraf

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4133814A (en) * 1975-10-28 1979-01-09 Eli Lilly And Company 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents
US4418068A (en) * 1981-04-03 1983-11-29 Eli Lilly And Company Antiestrogenic and antiandrugenic benzothiophenes
US4380635A (en) * 1981-04-03 1983-04-19 Eli Lilly And Company Synthesis of acylated benzothiophenes
US5075321A (en) * 1987-03-24 1991-12-24 University Of Pennsylvania Methods of treating diseases characterized by interactions of IgG-containing immune complexes with macrophage Fc receptors using antiestrogenic benzothiophenes
DE4122484A1 (de) * 1991-07-06 1993-01-07 Teves Gmbh Alfred Schaltungsanordnung zur erkennung von radsensordefekten
JP3157882B2 (ja) * 1991-11-15 2001-04-16 帝国臓器製薬株式会社 新規なベンゾチオフエン誘導体
TW366342B (en) * 1992-07-28 1999-08-11 Lilly Co Eli The use of 2-phenyl-3-aroylbenzothiophenes in inhibiting bone loss
TW303299B (de) * 1993-07-22 1997-04-21 Lilly Co Eli

Also Published As

Publication number Publication date
WO1996005825A1 (en) 1996-02-29
PT769945E (pt) 2003-09-30
FI970715A0 (fi) 1997-02-20
FI970715A (fi) 1997-02-20
NO970785D0 (no) 1997-02-20
CZ51997A3 (en) 1997-08-13
CA2198012A1 (en) 1996-02-29
MX9701332A (es) 1997-05-31
HUT76855A (en) 1997-12-29
ES2197207T3 (es) 2004-01-01
DE69530771T2 (de) 2004-03-11
JPH10504578A (ja) 1998-05-06
DK0769945T3 (da) 2003-06-10
AU3409795A (en) 1996-03-14
PH31620A (en) 1999-01-12
ZA956989B (en) 1997-02-21
EP0769945A1 (de) 1997-05-02
EP0769945A4 (de) 1997-09-03
AU701946B2 (en) 1999-02-11
ATE240101T1 (de) 2003-05-15
EP0769945B1 (de) 2003-05-14
US5502074A (en) 1996-03-26
DE69530771D1 (de) 2003-06-18
IL115016A0 (en) 1995-12-08
NO970785L (no) 1997-02-20
KR970705385A (ko) 1997-10-09

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed