IL114585A - Droloxifene for use as a medicament against prostate diseases endometriosis and obesity and medicament comprising same - Google Patents

Droloxifene for use as a medicament against prostate diseases endometriosis and obesity and medicament comprising same

Info

Publication number
IL114585A
IL114585A IL11458595A IL11458595A IL114585A IL 114585 A IL114585 A IL 114585A IL 11458595 A IL11458595 A IL 11458595A IL 11458595 A IL11458595 A IL 11458595A IL 114585 A IL114585 A IL 114585A
Authority
IL
Israel
Prior art keywords
medicament
droloxifene
obesity
same
against prostate
Prior art date
Application number
IL11458595A
Other languages
English (en)
Other versions
IL114585A0 (en
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of IL114585A0 publication Critical patent/IL114585A0/xx
Publication of IL114585A publication Critical patent/IL114585A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Vascular Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
IL11458595A 1994-07-19 1995-07-13 Droloxifene for use as a medicament against prostate diseases endometriosis and obesity and medicament comprising same IL114585A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/276,969 US5441986A (en) 1994-07-19 1994-07-19 Estrogen agonists as remedies for prostate and cardiovascular diseases

Publications (2)

Publication Number Publication Date
IL114585A0 IL114585A0 (en) 1995-11-27
IL114585A true IL114585A (en) 2000-01-31

Family

ID=23058874

Family Applications (2)

Application Number Title Priority Date Filing Date
IL11458595A IL114585A (en) 1994-07-19 1995-07-13 Droloxifene for use as a medicament against prostate diseases endometriosis and obesity and medicament comprising same
IL11458695A IL114586A (en) 1994-07-19 1995-07-13 Droloxifene for use in the treatment of cardiovascular diseases and pharmaceutical compositions comprising same

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL11458695A IL114586A (en) 1994-07-19 1995-07-13 Droloxifene for use in the treatment of cardiovascular diseases and pharmaceutical compositions comprising same

Country Status (17)

Country Link
US (4) US5441986A (xx)
EP (3) EP0771194A1 (xx)
JP (2) JP2930424B2 (xx)
KR (2) KR100212352B1 (xx)
CN (2) CN1152868A (xx)
AU (2) AU694220B2 (xx)
CA (2) CA2195213C (xx)
FI (2) FI970215A (xx)
HK (1) HK1000697A1 (xx)
HU (2) HUT77391A (xx)
IL (2) IL114585A (xx)
MX (2) MX9700534A (xx)
MY (1) MY113079A (xx)
NZ (2) NZ285158A (xx)
TW (1) TW403649B (xx)
WO (2) WO1996002243A1 (xx)
ZA (2) ZA955963B (xx)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6515009B1 (en) 1991-09-27 2003-02-04 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5811447A (en) 1993-01-28 1998-09-22 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6251920B1 (en) 1993-05-13 2001-06-26 Neorx Corporation Prevention and treatment of cardiovascular pathologies
US5770609A (en) 1993-01-28 1998-06-23 Neorx Corporation Prevention and treatment of cardiovascular pathologies
US6395494B1 (en) * 1993-05-13 2002-05-28 Neorx Corporation Method to determine TGF-β
US6491938B2 (en) 1993-05-13 2002-12-10 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5595722A (en) 1993-01-28 1997-01-21 Neorx Corporation Method for identifying an agent which increases TGF-beta levels
US5441986A (en) * 1994-07-19 1995-08-15 Pfizer Inc. Estrogen agonists as remedies for prostate and cardiovascular diseases
ATE377418T1 (de) 1995-06-07 2007-11-15 Poniard Pharmaceuticals Inc Vorbeugung und behandlung von kardiovaskulären beschwerden mit tamoxifen-analogen
US5985932A (en) * 1996-02-28 1999-11-16 Pfizer Inc Inhibition of autoimmune diseases
TW442286B (en) * 1996-02-28 2001-06-23 Pfizer New therapeutic uses of estrogen agonists
IL120266A (en) 1996-02-28 2005-05-17 Pfizer Use of estrogen antagonists and estrogen agonists in the preparation of medicaments for inhibiting pathological conditions
US5719190A (en) * 1996-02-28 1998-02-17 Pfizer Inc. Inhibition of myeloperoxidase activity
US5726207A (en) * 1996-02-28 1998-03-10 Pfizer Inc. Protection of ischemic myocardium against reperfusion damage
IL120270A0 (en) * 1996-02-28 1997-06-10 Pfizer Combination therapy to treat osteoporosis
US5733937A (en) * 1996-02-28 1998-03-31 Pfizer Inc. Methods for alleviating symptoms of premenstrual syndrome and late luteal phase dysphoric disorder
IL120262A (en) * 1996-02-28 2001-01-28 Pfizer Droloxifene and derivatives thereof for use in increasing serum testosterone levels
IL120269A0 (en) * 1996-02-28 1997-06-10 Pfizer 1,1,2-triphenylbut-1-ene derivatives for treating Alzheimer's disease
IL120263A0 (en) * 1996-02-28 1997-06-10 Pfizer Combination therapy to prevent bone loss-progesterone and estrogen agonists
IL120268A0 (en) * 1996-02-28 1997-06-10 Pfizer Use of (E)-1-[4'-(2-alkylaminoethioxy)phenyl]1-(3'-hydroxyphenyl)-2-phenylbut-1-enes in inhibiting pathological conditions
US6034102A (en) * 1996-11-15 2000-03-07 Pfizer Inc Atherosclerosis treatment
US6114395A (en) * 1996-11-15 2000-09-05 Pfizer Inc. Method of treating atherosclerosis
US6069175A (en) * 1996-11-15 2000-05-30 Pfizer Inc. Estrogen agonist/antagonists treatment of atherosclerosis
AU6959898A (en) * 1997-04-11 1998-11-11 David J. Grainger Compounds and therapies for the prevention of vascular and non-vascular pathol ogies
US20040186185A1 (en) * 1998-05-07 2004-09-23 Steiner Mitchell S. Method for treatment and chemoprevention of prostate cancer
US6413533B1 (en) * 1998-05-07 2002-07-02 The University Of Tennessee Research Corporation Method for chemoprevention of prostate cancer
US20040092602A1 (en) * 1998-05-07 2004-05-13 Steiner Mitchell S. Method for treatment and chemoprevention of prostate cancer
FI982733A (fi) 1998-12-17 2000-06-18 Orion Yhtymae Oyj Trifenyylietyleeniantiestrogeenien liukoisia koostumuksia
DK1175433T3 (da) 1999-05-04 2005-09-19 Strakan Int Ltd Androgenglycosider og androgen aktivitet deraf
AU5957500A (en) 1999-07-06 2001-01-22 Endorecherche Inc. Methods of treating and/or suppressing weight gain
TW593256B (en) 1999-11-16 2004-06-21 Hormos Medical Oy Ltd Triphenylalkene derivatives and their use as selective estrogen receptor modulators
CO5271709A1 (es) * 2000-01-12 2003-04-30 Pfizer Prod Inc Composiciones y procedimientos para el y tratamiento de afecciones que responden a estrogenos
US20080249183A1 (en) * 2001-11-29 2008-10-09 Steiner Mitchell S Treatment of androgen-deprivation induced osteoporosis
US20040248989A1 (en) 2003-06-05 2004-12-09 Risto Santti Method for the treatment or prevention of lower urinary tract symptoms
US20060270641A1 (en) * 2005-05-31 2006-11-30 Steiner Mitchell S Method for chemoprevention of prostate cancer
RU2480207C2 (ru) * 2006-05-22 2013-04-27 Хормос Медикал Лтд. Способ лечения хронического абактериального простатита селективными модуляторами рецепторов эстрогена или ингибиторами ароматазы
US7504530B2 (en) * 2007-02-14 2009-03-17 Hormos Medical Ltd. Methods for the preparation of fispemifene from ospemifene
JP5363344B2 (ja) * 2007-02-14 2013-12-11 ホルモス メディカル リミテッド 治療に有用なトリフェニルブテン誘導体の調製方法
WO2014060639A1 (en) 2012-10-19 2014-04-24 Fermion Oy A process for the preparation of ospemifene

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3046719C2 (de) * 1980-12-11 1983-02-17 Klinge Pharma GmbH, 8000 München 1,1,2-Triphenyl-but-1-en-Derivate, Verfahren zu ihrer Herstellung und Arzneimittel
DE3323321A1 (de) * 1983-06-24 1985-01-03 Schering AG, 1000 Berlin und 4709 Bergkamen Prophylaxe und therapie von koronaren herzkrankheiten durch senkung des oestrogenspiegels
US5262319A (en) * 1985-04-19 1993-11-16 Oncogene Science, Inc. Method for obtaining bone marrow free of tumor cells using transforming growth factor β3
FR2619383B1 (fr) * 1987-08-12 1989-12-08 Inst Vaisseaux Sang Proteine a activite vasculaire, derivee des monocytes et ses analogues, procede pour son extraction et leurs utilisations en therapeutique et pour la preparation d'anticorps
JPH04312526A (ja) * 1991-04-09 1992-11-04 Fujisawa Pharmaceut Co Ltd 骨疾患治療剤
DE4401554A1 (de) * 1993-02-16 1994-08-18 Freund Andreas Präparat zur Therapie und Prophylaxe von Erkrankungen, die bei Imbalancen von Plasmalipiden auftreten
US5384332A (en) * 1994-05-11 1995-01-24 Eli Lilly And Company Methods for inhibiting aortal smooth muscle cell proliferation and restenosis with 1,1,2-triphenylbut-1-ene derivatives
US5426123A (en) * 1994-05-11 1995-06-20 Eli Lilly And Company Method for lowering serum cholesterol with 1,1,2-triphenylbut-1-ene derivatives
US5455275A (en) * 1994-05-11 1995-10-03 Eli Lilly And Company Methods for inhibiting endometriosis and uterine fibroid disease with 1,1,2-triphenylbut-1-ene derivatives
US5441986A (en) * 1994-07-19 1995-08-15 Pfizer Inc. Estrogen agonists as remedies for prostate and cardiovascular diseases

Also Published As

Publication number Publication date
NZ285159A (en) 2000-10-27
AU2416995A (en) 1996-02-16
KR970704429A (ko) 1997-09-06
MY113079A (en) 2001-11-30
WO1996002242A1 (en) 1996-02-01
CN1076967C (zh) 2002-01-02
MX9700534A (es) 1997-04-30
EP1029540A3 (en) 2001-05-16
FI970215A0 (fi) 1997-01-17
FI970214A0 (fi) 1997-01-17
HU9700163D0 (en) 1997-03-28
KR100212352B1 (ko) 1999-08-02
IL114586A (en) 2000-06-29
JPH09507859A (ja) 1997-08-12
AU689257B2 (en) 1998-03-26
JPH09507860A (ja) 1997-08-12
FI970214A (fi) 1997-01-17
ZA955964B (en) 1997-01-20
FI970215A (fi) 1997-01-17
JP2930424B2 (ja) 1999-08-03
CN1153473A (zh) 1997-07-02
US5441986A (en) 1995-08-15
KR970704430A (ko) 1997-09-06
CA2195093A1 (en) 1996-02-01
CN1152868A (zh) 1997-06-25
KR100221854B1 (ko) 1999-09-15
CA2195213A1 (en) 1996-02-01
WO1996002243A1 (en) 1996-02-01
ZA955963B (en) 1997-01-20
AU2417095A (en) 1996-02-16
EP0769941A1 (en) 1997-05-02
HK1000697A1 (en) 2002-05-10
IL114586A0 (en) 1995-11-27
EP0771194A1 (en) 1997-05-07
MX9700538A (es) 1997-04-30
CA2195093C (en) 2000-03-07
AU694220B2 (en) 1998-07-16
HUT77391A (hu) 1998-04-28
CA2195213C (en) 2000-03-14
US5852059A (en) 1998-12-22
NZ285158A (en) 2000-07-28
HUT77392A (hu) 1998-04-28
EP1029540A2 (en) 2000-08-23
US5827892A (en) 1998-10-27
TW403649B (en) 2000-09-01
HU9700162D0 (en) 1997-03-28
IL114585A0 (en) 1995-11-27
US5902830A (en) 1999-05-11

Similar Documents

Publication Publication Date Title
IL114585A (en) Droloxifene for use as a medicament against prostate diseases endometriosis and obesity and medicament comprising same
IL116457A0 (en) Inhalation device
ZA951238B (en) Inhalation device
IL116492A0 (en) Therapeutic preparations for inhalation
CY2508B1 (en) Benzopyrans and their use as therapeutic agents
GB9402641D0 (en) Therapeutic agents
HUP9900612A3 (en) Novel hormonal medicaments and use thereof for correcting oestrogen deficiencies
GB9401879D0 (en) Therapeutic agents
GB9423267D0 (en) Compounding elements and use thereof
GB9403639D0 (en) Therapeutic agents
CA75178S (en) Medicament inhalation device
AU8934898A (en) Use of droloxifene for the treatment of prostatic diseases endometriosis and obesity
ZW1194A1 (en) Therapeutic agent
GB9406278D0 (en) Therapeutic agent
GB9626215D0 (en) A therapeutic agent and its use
ZA954541B (en) Therapeutic device
GB9414732D0 (en) Therapeutic device
ZA954732B (en) Benzopyrans and their use as therapeutic agents
PL301872A1 (en) Generally tonizing and immunostimulating pharmaceutical agent
GB9420340D0 (en) Therapeutic improvement
ZA9510505B (en) Therapeutic preparations for inhalation
GB9408693D0 (en) Medicament
GB9419954D0 (en) Medicament
GB9420703D0 (en) Medicament
GB9420189D0 (en) Inhalation device

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees