IL111970A - The Nzo-converted benzo compounds are a process for the preparation and compounds of myroquinine opponents containing them. - Google Patents

The Nzo-converted benzo compounds are a process for the preparation and compounds of myroquinine opponents containing them.

Info

Publication number
IL111970A
IL111970A IL11197094A IL11197094A IL111970A IL 111970 A IL111970 A IL 111970A IL 11197094 A IL11197094 A IL 11197094A IL 11197094 A IL11197094 A IL 11197094A IL 111970 A IL111970 A IL 111970A
Authority
IL
Israel
Prior art keywords
nitrogen
formula
alkyl
piperidino
radical
Prior art date
Application number
IL11197094A
Other languages
English (en)
Hebrew (he)
Other versions
IL111970A0 (en
Original Assignee
Zeneca Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB939325654A external-priority patent/GB9325654D0/en
Priority claimed from GB9423248A external-priority patent/GB9423248D0/en
Application filed by Zeneca Ltd filed Critical Zeneca Ltd
Publication of IL111970A0 publication Critical patent/IL111970A0/xx
Publication of IL111970A publication Critical patent/IL111970A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL11197094A 1993-12-15 1994-12-13 The Nzo-converted benzo compounds are a process for the preparation and compounds of myroquinine opponents containing them. IL111970A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB939325654A GB9325654D0 (en) 1993-12-15 1993-12-15 Cyclic amide derivatives
GB9423248A GB9423248D0 (en) 1994-11-17 1994-11-17 Cyclic amide derivatives

Publications (2)

Publication Number Publication Date
IL111970A0 IL111970A0 (en) 1995-03-15
IL111970A true IL111970A (en) 1999-03-12

Family

ID=26304034

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11197094A IL111970A (en) 1993-12-15 1994-12-13 The Nzo-converted benzo compounds are a process for the preparation and compounds of myroquinine opponents containing them.

Country Status (22)

Country Link
US (3) US5589489A (fr)
EP (1) EP0734383B1 (fr)
JP (1) JP3819934B2 (fr)
CN (1) CN1142822A (fr)
AT (1) ATE221064T1 (fr)
AU (1) AU690951B2 (fr)
BR (1) BR9408325A (fr)
CA (1) CA2176036A1 (fr)
CZ (1) CZ171796A3 (fr)
DE (1) DE69431069T2 (fr)
DK (1) DK0734383T3 (fr)
ES (1) ES2179094T3 (fr)
FI (1) FI962418A0 (fr)
HU (1) HUT76275A (fr)
IL (1) IL111970A (fr)
NO (1) NO962543L (fr)
NZ (1) NZ277291A (fr)
PL (1) PL315035A1 (fr)
PT (1) PT734383E (fr)
SG (1) SG52667A1 (fr)
SK (1) SK76396A3 (fr)
WO (1) WO1995016682A1 (fr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9322643D0 (en) * 1993-11-03 1993-12-22 Zeneca Ltd Lactam derivatives
GB9325074D0 (en) * 1993-12-07 1994-02-02 Zeneca Ltd Bicyclic heterocycles
GB9408872D0 (en) * 1994-05-03 1994-06-22 Zeneca Ltd Heterocyclic compounds
DE69534213T2 (de) * 1994-10-25 2006-01-12 Astrazeneca Ab Therapeutisch wirksame Heterocyclen
US5998444A (en) * 1995-10-24 1999-12-07 Zeneca Ltd. Piperidinyl compounds as NK1 or NK2 antagonists
US6008223A (en) * 1994-10-27 1999-12-28 Zeneca Limited Therapeutic compounds
GB9508786D0 (en) 1995-04-29 1995-06-21 Zeneca Ltd Substituted heterocycles
US5719156A (en) * 1995-05-02 1998-02-17 Schering Corporation Piperazino derivatives as neurokinin antagonists
GB9521781D0 (en) * 1995-10-24 1996-01-03 Merck Sharp & Dohme Therapeutic agents
GB9523526D0 (en) * 1995-11-17 1996-01-17 Zeneca Ltd Therapeutic compounds
CA2278309A1 (fr) * 1997-01-21 1998-07-23 Merck & Co., Inc. Piperidines 3,3-disubstituees utilisees comme modulateurs de l'activite de recepteurs de chemokines
US6124319A (en) * 1997-01-21 2000-09-26 Merck & Co., Inc. 3,3-disubstituted piperidines as modulators of chemokine receptor activity
US7671200B2 (en) 1999-10-27 2010-03-02 Cytokinetics, Inc. Quinazolinone KSP inhibitors
US7230000B1 (en) 1999-10-27 2007-06-12 Cytokinetics, Incorporated Methods and compositions utilizing quinazolinones
US6281248B1 (en) 2000-02-16 2001-08-28 Magda Abdel Fattah Ahmed Composition for treating asthma
US6846814B2 (en) 2000-04-06 2005-01-25 Astra Zeneca Ab Neurokinin antagonists for use as medicaments
US20050142495A1 (en) * 2003-10-09 2005-06-30 David Peter Van Heerden Methods of controlling multilayer foil ignition
US7441688B2 (en) * 2003-11-04 2008-10-28 Reactive Nanotechnologies Methods and device for controlling pressure in reactive multilayer joining and resulting product
US7121402B2 (en) * 2003-04-09 2006-10-17 Reactive Nano Technologies, Inc Container hermetically sealed with crushable material and reactive multilayer material
DE60223904T2 (de) 2001-01-26 2008-11-27 Btg International Ltd. Benzylaminanalogen
AU2004256020A1 (en) * 2003-05-13 2005-01-20 Johns Hopkins University Method of controlling thermal waves in reactive multilayer joining and resulting product
CA2570800A1 (fr) 2004-06-18 2006-01-26 Wyeth Procedes pour l'elaboration de 6-alkyle-5-arylsulfonye- dihydrophenanthridines
US9359367B2 (en) 2012-07-09 2016-06-07 Lupin Limited Tetrahydroquinazolinone derivatives as PARP inhibitors

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE903957A1 (en) * 1989-11-06 1991-05-08 Sanofi Sa Aromatic amine compounds, their method of preparation and¹pharmaceutical compositions in which they are present
FR2654725B1 (fr) * 1989-11-23 1992-02-14 Rhone Poulenc Sante Nouveaux derives de l'isoindolone, leur preparation et les compositions pharmaceutiques qui les contiennent.
IL99320A (en) * 1990-09-05 1995-07-31 Sanofi Sa Arylalkylamines, their preparation and pharmaceutical preparations containing them
FR2676053B1 (fr) * 1991-05-03 1993-08-27 Sanofi Elf Nouveaux composes dialkylenepiperidino et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant.
FR2676055B1 (fr) * 1991-05-03 1993-09-03 Sanofi Elf Composes polycycliques amines et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant.
FR2676054B1 (fr) * 1991-05-03 1993-09-03 Sanofi Elf Nouveaux composes n-alkylenepiperidino et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant.
FR2688219B1 (fr) * 1992-03-03 1994-07-08 Sanofi Elf Sels d'ammonium quaternaires de composes aromatiques amines, leur preparation et compositions pharmaceutiques les contenant.
GB9321557D0 (en) * 1992-11-03 1993-12-08 Zeneca Ltd Carboxamide derivatives
GB9310066D0 (en) * 1993-05-17 1993-06-30 Zeneca Ltd Alkyl substituted heterocycles
GB9310713D0 (en) * 1993-05-24 1993-07-07 Zeneca Ltd Aryl substituted heterocycles
CA2163995A1 (fr) * 1993-06-07 1994-12-22 Malcolm Maccoss Derives de substitution spiro d'azacycles, antagonistes de la neurokinine
GB9317104D0 (en) * 1993-08-17 1993-09-29 Zeneca Ltd Therapeutic heterocycles
GB9322643D0 (en) * 1993-11-03 1993-12-22 Zeneca Ltd Lactam derivatives

Also Published As

Publication number Publication date
SK76396A3 (en) 1996-12-04
DK0734383T3 (da) 2002-10-14
BR9408325A (pt) 1997-08-19
EP0734383B1 (fr) 2002-07-24
FI962418A (fi) 1996-06-11
US5589489A (en) 1996-12-31
AU690951B2 (en) 1998-05-07
AU1247195A (en) 1995-07-03
FI962418A0 (fi) 1996-06-11
PT734383E (pt) 2002-12-31
ES2179094T3 (es) 2003-01-16
SG52667A1 (en) 1998-09-28
HUT76275A (en) 1997-07-28
PL315035A1 (en) 1996-09-30
CZ171796A3 (en) 1996-09-11
DE69431069T2 (de) 2003-05-08
NZ277291A (en) 1997-12-19
CN1142822A (zh) 1997-02-12
WO1995016682A1 (fr) 1995-06-22
US5705505A (en) 1998-01-06
ATE221064T1 (de) 2002-08-15
NO962543D0 (no) 1996-06-14
IL111970A0 (en) 1995-03-15
JPH09506608A (ja) 1997-06-30
EP0734383A1 (fr) 1996-10-02
US5965576A (en) 1999-10-12
DE69431069D1 (de) 2002-08-29
NO962543L (no) 1996-08-14
CA2176036A1 (fr) 1995-06-22
JP3819934B2 (ja) 2006-09-13
HU9601568D0 (en) 1996-08-28

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees