IL111580A - Use of melatonin derivatives in the preparation of pharmaceutical compositions for use in treating sleep disorders - Google Patents

Use of melatonin derivatives in the preparation of pharmaceutical compositions for use in treating sleep disorders

Info

Publication number
IL111580A
IL111580A IL11158094A IL11158094A IL111580A IL 111580 A IL111580 A IL 111580A IL 11158094 A IL11158094 A IL 11158094A IL 11158094 A IL11158094 A IL 11158094A IL 111580 A IL111580 A IL 111580A
Authority
IL
Israel
Prior art keywords
sleep disorders
preparation
pharmaceutical compositions
treating sleep
melatonin derivatives
Prior art date
Application number
IL11158094A
Other languages
English (en)
Other versions
IL111580A0 (en
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of IL111580A0 publication Critical patent/IL111580A0/xx
Publication of IL111580A publication Critical patent/IL111580A/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • A61K31/405Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL11158094A 1993-11-18 1994-11-10 Use of melatonin derivatives in the preparation of pharmaceutical compositions for use in treating sleep disorders IL111580A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/154,332 US5654325A (en) 1993-11-18 1993-11-18 Melatonin derivatives for use in treating sleep disorders

Publications (2)

Publication Number Publication Date
IL111580A0 IL111580A0 (en) 1995-01-24
IL111580A true IL111580A (en) 1999-10-28

Family

ID=22550932

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11158094A IL111580A (en) 1993-11-18 1994-11-10 Use of melatonin derivatives in the preparation of pharmaceutical compositions for use in treating sleep disorders

Country Status (21)

Country Link
US (1) US5654325A (de)
EP (1) EP0655243B1 (de)
JP (1) JPH07196493A (de)
KR (1) KR950013508A (de)
CN (1) CN1092958C (de)
AT (1) ATE222491T1 (de)
AU (1) AU684313B2 (de)
CA (1) CA2135709C (de)
CZ (1) CZ288835B6 (de)
DE (1) DE69431199T2 (de)
DK (1) DK0655243T3 (de)
ES (1) ES2181702T3 (de)
HU (1) HUT72069A (de)
IL (1) IL111580A (de)
NO (1) NO309964B1 (de)
NZ (1) NZ264892A (de)
PH (1) PH31098A (de)
PT (1) PT655243E (de)
RU (1) RU2146140C1 (de)
SG (1) SG50505A1 (de)
ZA (1) ZA948927B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0748627A3 (de) * 1995-06-14 1997-05-21 Lilly Co Eli Melatoninagonisten zur Behandlung von gutartigen Hyperplasieformen der Prostata
CA2357114C (en) * 2001-03-22 2010-06-29 Pooger Properties Ltd. Use of melatonin in the manufacture of a medicament for treating attention deficit hyperactive disorder
WO2002079153A1 (en) * 2001-03-28 2002-10-10 Biocatalytics, Inc. Method for producing tryptamine derivatives
IL144900A (en) * 2001-08-14 2013-12-31 Neurim Pharma 1991 Melatonin and drugs containing it for use in the treatment of primary insomnia, and the manufacture of those drugs
AU2003270292A1 (en) * 2002-09-26 2004-04-19 Pooger Properties Limited Combined use of methylphenidate and melatonin for treating attention-deficit hyperactive disorder
US20070128310A1 (en) 2003-12-19 2007-06-07 Meni-One Co., Ltd. Astaxanthin-containing pet foods
WO2005062851A2 (en) * 2003-12-22 2005-07-14 Pappolla Miguel A Indole-3-propionamide and derivatives thereof
CA2556753C (en) * 2004-02-20 2014-11-25 Lifescape Biosciences Incorporated Compositions and methods for sleep regulation
DE102005008312A1 (de) * 2005-02-17 2006-08-24 Birds Pharma Gmbh Berolina Innovative Research & Development Services Verwendung deuterierter N-[2-(5-Methoxy-1H-indol-3-yl)-ethyl]acatamide und deren pharmazeutisch verträglicher Salze sowie diese Verbindungen enthaltende Arzneimittel
US20060223877A1 (en) * 2005-03-31 2006-10-05 Zemlan Frank P Methods of treatment utilizing certain melatonin derivatives
AR061478A1 (es) * 2006-06-19 2008-08-27 Takeda Pharmaceutical Compuesto triciclico y composicion farmaceutica
ES2324849A1 (es) * 2007-10-25 2009-08-17 Ferrer Internacional, S.A. Compuestos de indano.

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4087444A (en) * 1976-09-08 1978-05-02 Eli Lilly And Company Amides as ovulation inhibitors
IT1148618B (it) * 1982-10-11 1986-12-03 Polifarma Spa Procedimento enzimatico per la produzione di acido 3-indolpiruvico e utilizzazione farmaceutica di questo
US4600723A (en) * 1983-05-18 1986-07-15 Monash University Method for minimizing disturbances in circadian rhythms of bodily performance and function
EP0126630B1 (de) * 1983-05-18 1987-09-16 Monash University Verwendung von Melatonin zur Herstellung eines Arzneimittels
US4614807A (en) * 1984-10-04 1986-09-30 Eli Lilly And Company 6,7-dihalomelatonins
US4687763A (en) * 1985-02-25 1987-08-18 Massachusetts Institute Of Technology Composition and method for increasing levels or release of brain serotonin
US4997845A (en) * 1987-02-02 1991-03-05 Eli Lilly And Company β-alkylmelatonins as ovulation inhibitors
EP0375726A4 (en) * 1987-08-17 1991-01-30 Whitby Research Incorporated Melatonin analogues
US5093352A (en) * 1988-11-14 1992-03-03 Whitby Research, Inc. Antidepressant agents
JPH0418034A (ja) * 1990-05-11 1992-01-22 Kanegafuchi Chem Ind Co Ltd 点眼組成物
US5242941A (en) * 1990-12-04 1993-09-07 State Of Oregon Methods of treating circadian rhythm disorders
IT1251544B (it) * 1991-05-13 1995-05-17 Gabriele Biella Composizioni farmaceutiche attive nella terapia dei disturbi del sonno comprendenti melatonina o un suo derivato in associazione con un derivato benzodiazepinico
MX9205981A (es) * 1991-10-18 1993-04-01 Alza Corp Administracion transdermica de melatonina.
US5196435A (en) * 1991-11-21 1993-03-23 Eli Lilly And Company Melatonin derivatives and combinations with antiestrogen compounds for treating mammalian breast carcinoma
IT1255199B (it) * 1992-07-01 1995-10-20 Franco Fraschini Farmaco sintetizzato analogo della melatonina particolarmente efficacenelle patologie che interferiscono con i ritmi circadiani
IT1254995B (it) * 1992-06-24 1995-10-11 Farmaco contenente melatonina e/o agonisti, con somministrazione particolarmente efficace nelle patologie che interferiscono con i ritmi circandiani
US5449683A (en) * 1992-10-01 1995-09-12 Massachussetts Institute Of Technology Methods of inducing sleep using melatonin

Also Published As

Publication number Publication date
DE69431199D1 (de) 2002-09-26
NO309964B1 (no) 2001-04-30
JPH07196493A (ja) 1995-08-01
CA2135709C (en) 2007-01-02
PH31098A (en) 1998-02-05
DK0655243T3 (da) 2002-10-07
NZ264892A (en) 1997-07-27
RU94040886A (ru) 1996-09-20
CA2135709A1 (en) 1995-05-19
SG50505A1 (en) 1998-07-20
HU9403300D0 (en) 1995-01-30
RU2146140C1 (ru) 2000-03-10
CN1107701A (zh) 1995-09-06
CN1092958C (zh) 2002-10-23
ATE222491T1 (de) 2002-09-15
CZ288835B6 (cs) 2001-09-12
NO944339D0 (no) 1994-11-14
HUT72069A (en) 1996-03-28
PT655243E (pt) 2002-11-29
DE69431199T2 (de) 2003-03-27
NO944339L (no) 1995-05-19
ES2181702T3 (es) 2003-03-01
IL111580A0 (en) 1995-01-24
EP0655243A3 (de) 1995-10-11
EP0655243A2 (de) 1995-05-31
AU684313B2 (en) 1997-12-11
US5654325A (en) 1997-08-05
ZA948927B (en) 1996-05-10
KR950013508A (ko) 1995-06-15
AU7777794A (en) 1995-05-25
EP0655243B1 (de) 2002-08-21
CZ276594A3 (en) 1995-07-12

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees
NE Application for restoration - patent lapsed through non-payment of renewal fees (section 60, patents law, 5727-1967)
MM9K Patent not in force due to non-payment of renewal fees