IL110995A - PROCESS FOR PREPARING 2-SUBSTITUTED-3H-IMIDAZO £4, 5-b| PYRIDINE DERIVATIVES - Google Patents
PROCESS FOR PREPARING 2-SUBSTITUTED-3H-IMIDAZO £4, 5-b| PYRIDINE DERIVATIVESInfo
- Publication number
- IL110995A IL110995A IL110995A IL11099594A IL110995A IL 110995 A IL110995 A IL 110995A IL 110995 A IL110995 A IL 110995A IL 11099594 A IL11099594 A IL 11099594A IL 110995 A IL110995 A IL 110995A
- Authority
- IL
- Israel
- Prior art keywords
- general formula
- alkyl
- amidine
- aryl
- defined above
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH281593 | 1993-09-17 | ||
CN94116221A CN1045087C (zh) | 1993-09-17 | 1994-09-19 | 咪唑并吡啶类衍生物的制备方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
IL110995A0 IL110995A0 (en) | 1994-11-28 |
IL110995A true IL110995A (en) | 1998-02-08 |
Family
ID=36940453
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL110995A IL110995A (en) | 1993-09-17 | 1994-09-18 | PROCESS FOR PREPARING 2-SUBSTITUTED-3H-IMIDAZO £4, 5-b| PYRIDINE DERIVATIVES |
Country Status (20)
Country | Link |
---|---|
US (1) | US5446159A (es) |
EP (1) | EP0645388B1 (es) |
JP (1) | JPH07179464A (es) |
CN (2) | CN1105996A (es) |
AT (1) | ATE148701T1 (es) |
AU (1) | AU680024B2 (es) |
BR (1) | BR9403573A (es) |
CA (1) | CA2131134A1 (es) |
CZ (1) | CZ226594A3 (es) |
DE (1) | DE59401759D1 (es) |
DK (1) | DK0645388T3 (es) |
ES (1) | ES2097594T3 (es) |
GR (1) | GR3022501T3 (es) |
HU (1) | HU215605B (es) |
IL (1) | IL110995A (es) |
PL (1) | PL305066A1 (es) |
SI (1) | SI0645388T1 (es) |
SK (1) | SK111394A3 (es) |
TR (1) | TR27818A (es) |
ZA (1) | ZA947188B (es) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6092049A (en) * | 1995-06-30 | 2000-07-18 | Microsoft Corporation | Method and apparatus for efficiently recommending items using automated collaborative filtering and feature-guided automated collaborative filtering |
US6049777A (en) * | 1995-06-30 | 2000-04-11 | Microsoft Corporation | Computer-implemented collaborative filtering based method for recommending an item to a user |
US6112186A (en) * | 1995-06-30 | 2000-08-29 | Microsoft Corporation | Distributed system for facilitating exchange of user information and opinion using automated collaborative filtering |
BR9810508A (pt) | 1997-07-03 | 2000-09-05 | Du Pont Pharm Co | Composto, composição farmacêutica e método de tratamento de uma desordem |
US6465484B1 (en) | 1997-09-26 | 2002-10-15 | Merck & Co., Inc. | Angiogenesis inhibitors |
US6162804A (en) * | 1997-09-26 | 2000-12-19 | Merck & Co., Inc. | Tyrosine kinase inhibitors |
US6365589B1 (en) | 1998-07-02 | 2002-04-02 | Bristol-Myers Squibb Pharma Company | Imidazo-pyridines, -pyridazines, and -triazines as corticotropin releasing factor antagonists |
US6124463A (en) * | 1998-07-02 | 2000-09-26 | Dupont Pharmaceuticals | Benzimidazoles as corticotropin release factor antagonists |
AU760020B2 (en) * | 1998-08-31 | 2003-05-08 | Merck & Co., Inc. | Novel angiogenesis inhibitors |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4097525A (en) * | 1976-07-23 | 1978-06-27 | Pfizer Inc. | Aromatic amidines as antiviral agents in animals |
DE3324115A1 (de) * | 1983-07-05 | 1985-01-17 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue imidazole, ihre herstellung und diese verbindungen enthaltende arzneimittel |
FR2643903A1 (fr) * | 1989-03-03 | 1990-09-07 | Union Pharma Scient Appl | Nouveaux derives de benzimidazole, leurs procedes de preparation, intermediaires de synthese, compositions pharmaceutiques les contenant, utiles notamment pour le traitement des maladies cardiovasculaires, et des ulceres duodenaux |
US5223499A (en) * | 1989-05-30 | 1993-06-29 | Merck & Co., Inc. | 6-amino substituted imidazo[4,5-bipyridines as angiotensin II antagonists |
US5240938A (en) * | 1991-02-13 | 1993-08-31 | Merck & Co., Inc. | Angiotensin II antagonists incorporating a substituted pyridoimidazolyl ring |
US5066654A (en) * | 1990-10-22 | 1991-11-19 | A. H. Robins Company, Incorporated | 2-aryl-3-heterocyclicmethyl-3H-imidazo[4,5-b]pyridines as anxiolytics and anticonvulsants |
US5128327A (en) * | 1991-03-25 | 1992-07-07 | Merck & Co., Inc. | Angiotensin II antagonists incorporating a nitrogen containing six membered ring heterocycle |
-
1994
- 1994-08-30 CA CA002131134A patent/CA2131134A1/en not_active Abandoned
- 1994-09-13 JP JP6218370A patent/JPH07179464A/ja active Pending
- 1994-09-15 DE DE59401759T patent/DE59401759D1/de not_active Expired - Fee Related
- 1994-09-15 AT AT94114550T patent/ATE148701T1/de not_active IP Right Cessation
- 1994-09-15 SI SI9430035T patent/SI0645388T1/xx unknown
- 1994-09-15 ES ES94114550T patent/ES2097594T3/es not_active Expired - Lifetime
- 1994-09-15 DK DK94114550.0T patent/DK0645388T3/da active
- 1994-09-15 BR BR9403573A patent/BR9403573A/pt not_active Application Discontinuation
- 1994-09-15 EP EP94114550A patent/EP0645388B1/de not_active Expired - Lifetime
- 1994-09-15 TR TR00935/94A patent/TR27818A/xx unknown
- 1994-09-16 PL PL94305066A patent/PL305066A1/xx unknown
- 1994-09-16 SK SK1113-94A patent/SK111394A3/sk unknown
- 1994-09-16 AU AU73057/94A patent/AU680024B2/en not_active Ceased
- 1994-09-16 CZ CZ942265A patent/CZ226594A3/cs unknown
- 1994-09-16 CN CN94116128A patent/CN1105996A/zh active Pending
- 1994-09-16 ZA ZA947188A patent/ZA947188B/xx unknown
- 1994-09-16 HU HU9402664A patent/HU215605B/hu not_active IP Right Cessation
- 1994-09-18 IL IL110995A patent/IL110995A/en not_active IP Right Cessation
- 1994-09-19 CN CN94116221A patent/CN1045087C/zh not_active Expired - Fee Related
- 1994-09-19 US US08/308,431 patent/US5446159A/en not_active Expired - Fee Related
-
1997
- 1997-02-06 GR GR970400076T patent/GR3022501T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
CA2131134A1 (en) | 1995-03-18 |
DE59401759D1 (de) | 1997-03-20 |
PL305066A1 (en) | 1995-03-20 |
GR3022501T3 (en) | 1997-05-31 |
HU9402664D0 (en) | 1994-11-28 |
ATE148701T1 (de) | 1997-02-15 |
DK0645388T3 (da) | 1997-03-10 |
CN1105996A (zh) | 1995-08-02 |
ES2097594T3 (es) | 1997-04-01 |
TR27818A (tr) | 1995-08-29 |
EP0645388A1 (de) | 1995-03-29 |
AU7305794A (en) | 1995-03-30 |
JPH07179464A (ja) | 1995-07-18 |
BR9403573A (pt) | 1995-05-16 |
EP0645388B1 (de) | 1997-02-05 |
HUT68267A (en) | 1995-06-28 |
US5446159A (en) | 1995-08-29 |
ZA947188B (en) | 1995-05-11 |
CZ226594A3 (en) | 1995-04-12 |
CN1106009A (zh) | 1995-08-02 |
HU215605B (hu) | 1999-01-28 |
IL110995A0 (en) | 1994-11-28 |
SK111394A3 (en) | 1995-06-07 |
SI0645388T1 (es) | 1997-10-31 |
CN1045087C (zh) | 1999-09-15 |
AU680024B2 (en) | 1997-07-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB | Patent renewed | ||
RH | Patent void |