IL109508A - A skin healing system that contains estradiol or its consequence and a process for its preparation - Google Patents
A skin healing system that contains estradiol or its consequence and a process for its preparationInfo
- Publication number
- IL109508A IL109508A IL10950894A IL10950894A IL109508A IL 109508 A IL109508 A IL 109508A IL 10950894 A IL10950894 A IL 10950894A IL 10950894 A IL10950894 A IL 10950894A IL 109508 A IL109508 A IL 109508A
- Authority
- IL
- Israel
- Prior art keywords
- transdermal therapeutic
- therapeutic system
- pressure sensitive
- sensitive adhesive
- estradiol
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7076—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising ingredients of undetermined constitution or reaction products thereof, e.g. rosin or other plant resins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Dermatology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Botany (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4314970 | 1993-05-06 | ||
DE4336557A DE4336557C2 (de) | 1993-05-06 | 1993-10-27 | Estradiolhaltiges transdermales therapeutisches System, Verfahren zu seiner Herstellung und seine Verwendung |
Publications (2)
Publication Number | Publication Date |
---|---|
IL109508A0 IL109508A0 (en) | 1994-08-26 |
IL109508A true IL109508A (en) | 1998-10-30 |
Family
ID=25925640
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL10950894A IL109508A (en) | 1993-05-06 | 1994-05-02 | A skin healing system that contains estradiol or its consequence and a process for its preparation |
Country Status (28)
Country | Link |
---|---|
US (2) | US6143319A (pt) |
EP (1) | EP0697860B1 (pt) |
JP (1) | JP3885233B2 (pt) |
KR (1) | KR100343877B1 (pt) |
CN (1) | CN1136843C (pt) |
AT (1) | ATE196843T1 (pt) |
AU (1) | AU696816B2 (pt) |
CA (1) | CA2160775C (pt) |
CZ (1) | CZ291656B6 (pt) |
DE (2) | DE4336557C2 (pt) |
DK (1) | DK0697860T3 (pt) |
ES (1) | ES2152979T3 (pt) |
FI (1) | FI115034B (pt) |
GR (1) | GR3035200T3 (pt) |
HU (1) | HU221166B1 (pt) |
IL (1) | IL109508A (pt) |
MX (1) | MXPA94003365A (pt) |
MY (1) | MY111515A (pt) |
NO (1) | NO309891B1 (pt) |
NZ (1) | NZ266140A (pt) |
PL (1) | PL179962B1 (pt) |
PT (1) | PT697860E (pt) |
RU (1) | RU2140784C1 (pt) |
SI (1) | SI0697860T1 (pt) |
SK (1) | SK282230B6 (pt) |
TW (1) | TW382599B (pt) |
UA (1) | UA29476C2 (pt) |
WO (1) | WO1994026257A1 (pt) |
Families Citing this family (92)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GR1002079B (en) * | 1994-07-26 | 1995-12-05 | Lavipharm A E | System of a special structure and composition for the rapid transdermal administration of oestrogens. |
DE19500662C2 (de) * | 1995-01-12 | 2001-04-26 | Lohmann Therapie Syst Lts | Estradiolhaltiges Pflaster und seine Verwendung |
DE19501022C1 (de) * | 1995-01-14 | 1996-06-05 | Lohmann Therapie Syst Lts | Transdermales therapeutisches System zur Verabreichung von (s)-3-Methyl-5-(1-methyl-2-pyrrolidenyl)-isoxazol oder einem seiner pharmazeutisch akzeptablen Salze und Verfahren zu seiner Herstellung |
AU719171B2 (en) * | 1995-01-14 | 2000-05-04 | Abbott Laboratories | A transdermal therapeutic system for the administration of (s)-3-methyl-5-(1-methyl-2-pyrrolidinyl)-isoxazole or one of its pharmaceutically acceptable salts |
DE19713141A1 (de) * | 1996-03-29 | 1997-10-30 | Labtec Gmbh | Transdermales System mit Melatonin |
DE19828273B4 (de) | 1998-06-25 | 2005-02-24 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches System, enthaltend Hormone und Kristallisationsinhibitoren |
DE19830651A1 (de) * | 1998-07-09 | 2000-01-13 | Lohmann Therapie Syst Lts | Steroidhaltiges Pflaster, Verfahren zu seiner Herstellung und Verwendung |
EP1140021B1 (en) | 1998-12-23 | 2004-08-04 | Idea Ag | Improved formulation for topical non-invasive application in vivo |
PT1031347E (pt) | 1999-01-27 | 2002-09-30 | Idea Ag | Transporte/imunizacao transnasal com veiculos muitissimo adaptaveis |
DK1031346T3 (da) | 1999-01-27 | 2002-08-12 | Idea Ag | Ikke-invasiv vaccination gennem huden |
TWI248820B (en) * | 1999-03-03 | 2006-02-11 | Nitto Denko Corp | Oral adhesive sheet and oral adhesive preparation |
PT1191927E (pt) | 1999-07-02 | 2003-07-31 | Lohmann Therapie Syst Lts | Sistema de microrreservatorios a base de polissiloxanos e solventes ambifilicos |
WO2001001962A1 (en) | 1999-07-05 | 2001-01-11 | Idea Ag. | A method for the improvement of transport across adaptable semi-permeable barriers |
RU2266735C2 (ru) * | 1999-11-29 | 2005-12-27 | Лтс Ломанн Терапи-Системе Аг | Трансдермальные терапевтические системы с повышенной стабильностью и способ их получения |
DE10054713C2 (de) * | 1999-11-29 | 2002-07-18 | Lohmann Therapie Syst Lts | Transdermale Therapeutische Systeme mit verbesserter Stabilität und ein Verfahren zu ihrer Herstellung |
AU3104301A (en) | 2000-01-20 | 2001-07-31 | Noven Pharmaceuticals, Inc. | Compositions and methods to effect the release profile in the transdermal administration of active agents |
ATE517614T1 (de) * | 2000-04-18 | 2011-08-15 | Hisamitsu Pharmaceutical Co | Pflaster enthaltend einen anti-inflammatorischen wirkstoff |
TWI287455B (en) * | 2000-12-05 | 2007-10-01 | Noven Pharma | Crystallization inhibition of drugs in transdermal drug delivery systems and methods of use |
ATE526973T1 (de) * | 2001-06-18 | 2011-10-15 | Noven Pharma | Verbesserte arzneimittelabgabe in transdermalen systemen |
US20040018237A1 (en) | 2002-05-31 | 2004-01-29 | Perricone Nicholas V. | Topical drug delivery using phosphatidylcholine |
US8435942B2 (en) * | 2002-05-31 | 2013-05-07 | Transdermal Biotechnology, Inc. | Methods for formulating stabilized insulin compositions |
US7473432B2 (en) | 2002-10-11 | 2009-01-06 | Idea Ag | NSAID formulations, based on highly adaptable aggregates, for improved transport through barriers and topical drug delivery |
AU2004212675B2 (en) | 2003-02-21 | 2006-06-01 | Bayer Intellectual Property Gmbh | UV stable transdermal therapeutic plaster |
UA89766C2 (en) | 2003-12-12 | 2010-03-10 | Байер Шеринг Фарма Акциенгезельшафт | Transdermal delivery system of gestodene |
US8668925B2 (en) * | 2003-12-12 | 2014-03-11 | Bayer Intellectual Property Gmbh | Transdermal delivery of hormones without the need of penetration enhancers |
WO2006091795A2 (en) * | 2005-02-25 | 2006-08-31 | Board Of Regents, The University Of Texas System | METHODS AND COMPOSITIONS INVOLVING EXPRESSION OF α1C SUBUNIT OF L-TYPE CALCIUM CHANNELS IN SMOOTH MUSCLE CELLS |
US8962013B2 (en) * | 2005-05-02 | 2015-02-24 | Bayer Intellectual Property Gmbh | Multi-layered transdermal system with triazine UV absorber |
EP1893159B1 (en) | 2005-06-17 | 2015-09-30 | Vital Health Sciences Pty Ltd. | A carrier comprising one or more di- and/or monophosphate derivatives of electron transfer agents |
US20070259029A1 (en) * | 2006-05-08 | 2007-11-08 | Mcentire Edward Enns | Water-dispersible patch containing an active agent for dermal delivery |
US20070258935A1 (en) * | 2006-05-08 | 2007-11-08 | Mcentire Edward Enns | Water dispersible films for delivery of active agents to the epidermis |
US20080057090A1 (en) * | 2006-09-01 | 2008-03-06 | Mcentire Edward Enns | Wrinkle masking film composition for skin |
US7879942B2 (en) | 2006-10-05 | 2011-02-01 | Eastman Chemical Company | Switchable adhesive article for attachment to skin and method of using the same |
WO2008136699A1 (fr) * | 2007-05-04 | 2008-11-13 | Igor Alexandrovich Bazikov | Patch transdermique à microcapsules et procédé de fabrication correspondant |
MX2012011355A (es) | 2010-03-30 | 2012-11-30 | Phosphagenics Ltd | Parche de suministro transdermico. |
HUE031326T2 (hu) | 2010-09-06 | 2017-07-28 | Bayer Ip Gmbh | Alacsony dózisú transzdermális tapaszok magas hatóanyagleadással |
DE102010040299A1 (de) | 2010-09-06 | 2012-03-08 | Bayer Schering Pharma Aktiengesellschaft | Transdermale therapeutische Systeme mit kristallisationsinhibierender Schutzfolie (Release Liner) |
US9561243B2 (en) | 2011-03-15 | 2017-02-07 | Phosphagenics Limited | Composition comprising non-neutralised tocol phosphate and a vitamin A compound |
WO2012125214A1 (en) | 2011-03-17 | 2012-09-20 | Transdermal Biotechnology, Inc. | Topical nitric oxide systems and methods of use thereof |
EP3936133A1 (en) | 2011-11-23 | 2022-01-12 | TherapeuticsMD, Inc. | Natural combination hormone replacement formulations and therapies |
US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
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US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
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US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
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US9295636B2 (en) | 2013-03-13 | 2016-03-29 | Transdermal Biotechnology, Inc. | Wound healing using topical systems and methods |
US9724419B2 (en) | 2013-03-13 | 2017-08-08 | Transdermal Biotechnology, Inc. | Peptide systems and methods for metabolic conditions |
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US9849160B2 (en) | 2013-03-13 | 2017-12-26 | Transdermal Biotechnology, Inc. | Methods and systems for treating or preventing cancer |
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US9393265B2 (en) | 2013-03-13 | 2016-07-19 | Transdermal Biotechnology, Inc. | Wound healing using topical systems and methods |
US9314422B2 (en) | 2013-03-13 | 2016-04-19 | Transdermal Biotechnology, Inc. | Peptide systems and methods for metabolic conditions |
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CN104546804A (zh) * | 2013-10-09 | 2015-04-29 | 上海现代药物制剂工程研究中心有限公司 | 三维网状立体构型的透皮给药制剂及其制备方法 |
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CN104840449B (zh) * | 2015-04-22 | 2018-05-18 | 崔建平 | 一种药物贴剂及其制备方法 |
US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
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RU2648470C2 (ru) * | 2016-03-03 | 2018-03-26 | Государственное бюджетное образовательное учреждение высшего профессионального образования "Уральский государственный медицинский университет Министерства здравоохранения Российской Федерации" (ГБОУ ВПО УГМУ Минздрава России) | Способ оптимизации лечения женщин кардиотропной терапией и заместительной гормональной терапией при эстрогенодефиците с артериальной гипертензией в позднем репродуктивном периоде |
BR112018070199A2 (pt) | 2016-04-01 | 2019-01-29 | Therapeuticsmd Inc | composição farmacêutica de hormônio esteroide |
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DE4223360C1 (pt) * | 1992-07-16 | 1993-04-08 | Lts Lohmann Therapie-Systeme Gmbh & Co Kg, 5450 Neuwied, De | |
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-
1993
- 1993-10-27 DE DE4336557A patent/DE4336557C2/de not_active Expired - Lifetime
-
1994
- 1994-04-22 MY MYPI94000991A patent/MY111515A/en unknown
- 1994-04-25 AT AT94915533T patent/ATE196843T1/de active
- 1994-04-25 SI SI9430354T patent/SI0697860T1/xx unknown
- 1994-04-25 CA CA002160775A patent/CA2160775C/en not_active Expired - Lifetime
- 1994-04-25 AU AU67213/94A patent/AU696816B2/en not_active Expired
- 1994-04-25 PT PT94915533T patent/PT697860E/pt unknown
- 1994-04-25 CZ CZ19952892A patent/CZ291656B6/cs not_active IP Right Cessation
- 1994-04-25 SK SK1379-95A patent/SK282230B6/sk not_active IP Right Cessation
- 1994-04-25 HU HU9503168A patent/HU221166B1/hu unknown
- 1994-04-25 EP EP94915533A patent/EP0697860B1/de not_active Expired - Lifetime
- 1994-04-25 KR KR1019950705046A patent/KR100343877B1/ko not_active IP Right Cessation
- 1994-04-25 ES ES94915533T patent/ES2152979T3/es not_active Expired - Lifetime
- 1994-04-25 PL PL94311590A patent/PL179962B1/pl unknown
- 1994-04-25 WO PCT/EP1994/001279 patent/WO1994026257A1/de active IP Right Grant
- 1994-04-25 CN CNB941920070A patent/CN1136843C/zh not_active Expired - Lifetime
- 1994-04-25 RU RU95122633A patent/RU2140784C1/ru active
- 1994-04-25 UA UA95114785A patent/UA29476C2/uk unknown
- 1994-04-25 DE DE59409548T patent/DE59409548D1/de not_active Expired - Lifetime
- 1994-04-25 NZ NZ266140A patent/NZ266140A/en not_active IP Right Cessation
- 1994-04-25 DK DK94915533T patent/DK0697860T3/da active
- 1994-04-25 JP JP52486094A patent/JP3885233B2/ja not_active Expired - Lifetime
- 1994-05-02 IL IL10950894A patent/IL109508A/en not_active IP Right Cessation
- 1994-05-06 MX MXPA94003365A patent/MXPA94003365A/es active IP Right Grant
- 1994-06-17 TW TW083105530A patent/TW382599B/zh not_active IP Right Cessation
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1995
- 1995-11-02 FI FI955259A patent/FI115034B/fi not_active IP Right Cessation
- 1995-11-03 NO NO954413A patent/NO309891B1/no not_active IP Right Cessation
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1997
- 1997-10-30 US US08/961,039 patent/US6143319A/en not_active Expired - Lifetime
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2000
- 2000-03-10 US US09/522,925 patent/US6521250B2/en not_active Expired - Lifetime
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2001
- 2001-01-10 GR GR20010400018T patent/GR3035200T3/el unknown
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