IL109311A0 - 1H-indole-3-acetamide sPla2 inhibitors - Google Patents
1H-indole-3-acetamide sPla2 inhibitorsInfo
- Publication number
- IL109311A0 IL109311A0 IL10931194A IL10931194A IL109311A0 IL 109311 A0 IL109311 A0 IL 109311A0 IL 10931194 A IL10931194 A IL 10931194A IL 10931194 A IL10931194 A IL 10931194A IL 109311 A0 IL109311 A0 IL 109311A0
- Authority
- IL
- Israel
- Prior art keywords
- indole
- spla2 inhibitors
- acetamide
- acetamide spla2
- inhibitors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/22—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an aralkyl radical attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an alkyl or cycloalkyl radical attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/572—Five-membered rings
- C07F9/5728—Five-membered rings condensed with carbocyclic rings or carbocyclic ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Nutrition Science (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pain & Pain Management (AREA)
- Oncology (AREA)
- Rheumatology (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4862993A | 1993-04-16 | 1993-04-16 | |
| US20872194A | 1994-03-15 | 1994-03-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL109311A0 true IL109311A0 (en) | 1994-07-31 |
Family
ID=26726342
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL10931194A IL109311A0 (en) | 1993-04-16 | 1994-04-12 | 1H-indole-3-acetamide sPla2 inhibitors |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US5684034A (show.php) |
| EP (1) | EP0620215B1 (show.php) |
| JP (1) | JPH0725850A (show.php) |
| KR (1) | KR100317755B1 (show.php) |
| CN (1) | CN1068588C (show.php) |
| AT (1) | ATE183503T1 (show.php) |
| AU (1) | AU676884B2 (show.php) |
| BR (1) | BR9401482A (show.php) |
| CA (1) | CA2121323A1 (show.php) |
| CO (1) | CO4230092A1 (show.php) |
| CZ (1) | CZ289750B6 (show.php) |
| DE (1) | DE69420068T2 (show.php) |
| DK (1) | DK0620215T3 (show.php) |
| ES (1) | ES2138648T3 (show.php) |
| FI (1) | FI941767A7 (show.php) |
| GR (1) | GR3031783T3 (show.php) |
| HU (1) | HUT70836A (show.php) |
| IL (1) | IL109311A0 (show.php) |
| NO (1) | NO300732B1 (show.php) |
| NZ (1) | NZ260298A (show.php) |
| PL (1) | PL181319B1 (show.php) |
| RU (1) | RU2162463C2 (show.php) |
| TW (1) | TW268942B (show.php) |
| UA (1) | UA44218C2 (show.php) |
| YU (1) | YU20194A (show.php) |
Families Citing this family (69)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL109311A0 (en) * | 1993-04-16 | 1994-07-31 | Lilly Co Eli | 1H-indole-3-acetamide sPla2 inhibitors |
| IL109309A (en) * | 1993-04-16 | 2000-06-29 | Lilly Co Eli | 1-H-indole-3-acetic acid hydrazide SPLA2 inhibitors and pharmaceutical compositions containing them |
| US6252084B1 (en) | 1994-03-15 | 2001-06-26 | Eli Lilly And Company | 1H-indole-3-acetamide sPLA2 inhibitors |
| AU688458B2 (en) * | 1994-04-01 | 1998-03-12 | Eli Lilly And Company | 1H-indole-3-glyoxylamide sPLA2 inhibitors |
| US5641800A (en) * | 1994-07-21 | 1997-06-24 | Eli Lilly And Company | 1H-indole-1-functional sPLA2 inhibitors |
| US6214876B1 (en) | 1994-07-21 | 2001-04-10 | Eli Lilly And Company | Indene-1-acetamide sPLA2 inhibitors |
| EP0922028A1 (en) * | 1996-08-26 | 1999-06-16 | Genetics Institute, Inc. | Inhibitors of phospholipase enzymes |
| US6630496B1 (en) | 1996-08-26 | 2003-10-07 | Genetics Institute Llc | Inhibitors of phospholipase enzymes |
| TR199900956T2 (xx) * | 1996-10-30 | 1999-07-21 | Eli Lilly And Company | S�bstit�e edilmi� trisiklik bile�imler. |
| US6569539B2 (en) | 1996-10-30 | 2003-05-27 | Tetra Level Holdings & Finance S.A. | Gas barrier packaging laminate method for production thereof and packaging containers |
| US6713645B1 (en) * | 1996-10-30 | 2004-03-30 | Eli Lilly And Company | Substituted tricyclics |
| US5919774A (en) * | 1996-12-10 | 1999-07-06 | Eli Lilly And Company | Pyrroles as sPLA2 inhibitors |
| WO1998037069A1 (en) * | 1997-02-20 | 1998-08-27 | Shionogi & Co., Ltd. | Indole dicarboxylic acid derivatives |
| US6828344B1 (en) | 1998-02-25 | 2004-12-07 | Genetics Institute, Llc | Inhibitors of phospholipase enzymes |
| US6916841B2 (en) | 1998-02-25 | 2005-07-12 | Genetics Institute, Llc | Inhibitors of phospholipase enzymes |
| SK12752000A3 (sk) * | 1998-02-25 | 2001-03-12 | Genetics Institute, Inc. | Inhibítory fosfolipázových enzýmov, farmaceutický prostriedok s ich obsahom a ich použitie |
| CN1299347A (zh) * | 1998-02-25 | 2001-06-13 | 遗传研究所有限公司 | 磷脂酶抑制剂 |
| JP2002504551A (ja) * | 1998-02-25 | 2002-02-12 | ジェネティックス・インスチチュート・インコーポレーテッド | ホスホリパーゼａ２の阻害剤 |
| US6500853B1 (en) | 1998-02-28 | 2002-12-31 | Genetics Institute, Llc | Inhibitors of phospholipase enzymes |
| US6407104B1 (en) | 1998-03-31 | 2002-06-18 | Shionogi & Co., Ltd. | Pyrrolo[1,2-a]pyrazine spla2 inhibitor |
| DZ2769A1 (fr) * | 1998-04-17 | 2003-12-01 | Lilly Co Eli | Composés tricycliques substitués. |
| ID23219A (id) * | 1998-04-17 | 2000-03-30 | Lilly Co Eli | Trisiklik tersubstitusi |
| CN1302300A (zh) | 1998-05-21 | 2001-07-04 | 盐野义制药株式会社 | 吡咯并[1,2－b]哒嗪sPLA2抑制剂 |
| JP2002522385A (ja) | 1998-08-03 | 2002-07-23 | イーライ・リリー・アンド・カンパニー | インドールｓＰＬＡ２インヒビター |
| JP2002522386A (ja) * | 1998-08-03 | 2002-07-23 | イーライ・リリー・アンド・カンパニー | インドールｓＰＬＡ２インヒビター |
| WO2000010568A1 (en) | 1998-08-24 | 2000-03-02 | Draheim Susan E | Methods and compositions for treating periodontal disease with an inhibitor of secretory phospholipase a¿2? |
| US7098237B1 (en) | 1998-10-14 | 2006-08-29 | Shionogi & Co., Ltd. | Remedies for ischemia reperfusion injury |
| US6448284B1 (en) | 1998-12-22 | 2002-09-10 | Eli Lilly And Company | Substituted tricyclics |
| WO2001005789A1 (en) | 1999-07-19 | 2001-01-25 | Shionogi & Co., Ltd. | TRICYCLIC COMPOUNDS HAVING sPLA2-INHIBITORY ACTIVITIES |
| US6706752B1 (en) | 1999-07-19 | 2004-03-16 | Eli Lilly And Company | sPLA2 inhibitors |
| AU5873400A (en) * | 1999-07-19 | 2001-02-05 | Eli Lilly And Company | spla2 inhibitors |
| AU6023200A (en) | 1999-08-02 | 2001-02-19 | Shionogi & Co., Ltd. | Tricyclic compounds having spla2-inhibitory activities |
| WO2001014378A1 (en) | 1999-08-23 | 2001-03-01 | Shionogi & Co., Ltd. | PYRROLOTRIAZINE DERIVATIVES HAVING sPLA2-INHIBITORY ACTIVITIES |
| JP2003509491A (ja) * | 1999-09-20 | 2003-03-11 | イーライ・リリー・アンド・カンパニー | 新規なｓＰＬＡ２インヒビター |
| US6831095B1 (en) | 1999-09-20 | 2004-12-14 | Eli Lilly And Company | Hydroxyfunctional amide 1h-indole derivatives active as sPLA2 inhibitors |
| WO2001026653A1 (en) * | 1999-10-15 | 2001-04-19 | Shionogi & Co., Ltd. | V TYPE AND/OR X TYPE sPLA2 INHIBITORS |
| WO2001036420A1 (en) | 1999-11-15 | 2001-05-25 | Shionogi & Co., Ltd. | Tricyclic azaindolizine derivatives having an spla2- inhibiting effect |
| DE19962300A1 (de) * | 1999-12-23 | 2001-06-28 | Asta Medica Ag | Substituierte N-Benzyl-Indol-3-yl-glyoxylsäure-Derivate mit Antitumorwirkung |
| US6608059B1 (en) | 2000-06-27 | 2003-08-19 | Smithkline Beecham Corporation | Fatty acid synthase inhibitors |
| US7026318B2 (en) | 2000-06-29 | 2006-04-11 | Shionogi & Co., Ltd. | Compounds exhibiting X-type sPLA2 inhibiting effect |
| US6967200B2 (en) | 2000-06-29 | 2005-11-22 | Shionogi & Co., Ltd. | Remedies for cirrhosis |
| GB0016162D0 (en) * | 2000-06-30 | 2000-08-23 | Cancer Res Campaign Tech | Indole-3-acetic acid derivatives |
| US20050203166A1 (en) * | 2000-06-30 | 2005-09-15 | Cancer Research Technology Limited | Indole-3-acetic acid derivatives |
| BR0112460A (pt) * | 2000-07-14 | 2003-07-22 | Lilly Co Eli | Método para tratamento de sépsis |
| WO2002020478A1 (en) * | 2000-08-24 | 2002-03-14 | Dublin City University | N-benzylindole-3-acetic acid derivatives for use in the treatment of drug resistan cancer |
| WO2002050030A2 (en) * | 2000-12-18 | 2002-06-27 | Eli Lilly And Company | Cycloalkylfused [g]-indole compounds as spla2-inhibitors in the treatment of inflammatory diseases |
| CA2431506A1 (en) | 2000-12-18 | 2002-07-25 | Eli Lilly And Company | Benz(g) indoles and their use as spla2 inhibitors |
| TWI314457B (show.php) | 2001-03-19 | 2009-09-11 | Shionogi & Co | |
| US7713964B2 (en) | 2001-12-03 | 2010-05-11 | Wyeth Llc | Methods for treating asthmatic conditions |
| US6797708B2 (en) | 2001-12-03 | 2004-09-28 | Wyeth | Inhibitors of cytosolic phospholipase A2 |
| US7605156B2 (en) | 2001-12-03 | 2009-10-20 | Wyeth | Methods for the use of inhibitors of cytosolic phospholipase A2 |
| US7101875B2 (en) | 2001-12-03 | 2006-09-05 | Wyeth | Methods for treating arthritic disorders |
| US6984735B2 (en) | 2001-12-03 | 2006-01-10 | Wyeth | Process for making an aldehyde |
| US6635771B2 (en) | 2001-12-03 | 2003-10-21 | Wyeth | N-benzhydryl indole compounds |
| US7129264B2 (en) * | 2003-04-16 | 2006-10-31 | Bristol-Myers Squibb Company | Biarylmethyl indolines and indoles as antithromboembolic agents |
| US20070161698A1 (en) * | 2003-05-30 | 2007-07-12 | Microbia, Inc. | Modulators of CRTH2 Activity |
| WO2005002525A2 (en) * | 2003-07-01 | 2005-01-13 | Microbia, Inc. | Cox-2 and faah inhibitors |
| WO2005037227A2 (en) * | 2003-10-16 | 2005-04-28 | Microbia, Inc. | Selective cox-2 inhibitors |
| US7417063B2 (en) * | 2004-04-13 | 2008-08-26 | Bristol-Myers Squibb Company | Bicyclic heterocycles useful as serine protease inhibitors |
| US20050234030A1 (en) * | 2004-04-20 | 2005-10-20 | Wilmin Bartolini | Modulators of CRTH2, COX-2 and FAAH |
| US20050234244A1 (en) * | 2004-04-20 | 2005-10-20 | Wilmin Bartolini | Synthesis of COX-2 and FAAH inhibitors |
| GT200600228A (es) | 2005-05-27 | 2006-12-26 | Inhibidores de la fosfolipasa a2 citosolica | |
| WO2007022501A2 (en) * | 2005-08-18 | 2007-02-22 | Microbia, Inc. | Useful indole compounds |
| WO2007056281A2 (en) | 2005-11-03 | 2007-05-18 | Ilypsa, Inc. | Multivalent indole compounds and use thereof as phospholipase-a2 inhibitors |
| JP2009517341A (ja) * | 2005-11-03 | 2009-04-30 | イリプサ， インコーポレイテッド | Ｃ４−アミド置換基を有するインドール化合物およびホスホリパーゼａ２インヒビターとしてのその使用 |
| GB2431927B (en) * | 2005-11-04 | 2010-03-17 | Amira Pharmaceuticals Inc | 5-Lipoxygenase-activating protein (FLAP) inhibitors |
| US8048880B2 (en) * | 2007-05-03 | 2011-11-01 | Anthera Pharmaceuticals, Inc. | Treatment of cardiovascular disease and dyslipidemia using secretory phospholipase A2 (SPLA2) inhibitors and SPLA2 inhibitor combination therapies |
| EP4008327A1 (en) | 2009-04-29 | 2022-06-08 | Amarin Pharmaceuticals Ireland Limited | Pharmaceutical compositions comprising epa and a cardiovascular agent and methods of using the same |
| CN105384619B (zh) * | 2014-08-22 | 2020-05-29 | 四川海思科制药有限公司 | 一种异丙基苯酚衍生物及其制备方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2825734A (en) * | 1955-04-11 | 1958-03-04 | Upjohn Co | Reduction of carbonylic radicals in indolyl-3 compounds |
| US2890223A (en) * | 1956-03-22 | 1959-06-09 | Research Corp | 1-benzyl, 2-methyl, 5-methoxy tryptamine |
| US3242193A (en) * | 1961-03-13 | 1966-03-22 | Merck & Co Inc | Indolyl aliphatic acids |
| US3196162A (en) * | 1961-03-13 | 1965-07-20 | Merck & Co Inc | Indolyl aliphatic acids |
| US3242162A (en) * | 1961-03-13 | 1966-03-22 | Merck & Co Inc | Indolyl aliphatic acids |
| US3242163A (en) * | 1961-03-13 | 1966-03-22 | Merck & Co Inc | Indolyl aliphatic acids |
| US3271416A (en) * | 1961-10-24 | 1966-09-06 | Merck & Co Inc | Indolyl aliphatic acids |
| US3259622A (en) * | 1962-09-07 | 1966-07-05 | Merck & Co Inc | 1-benzyl-3-indolyl-alpha-haloalkyl and alkylidenyl acetic acids |
| US4428962A (en) * | 1981-10-30 | 1984-01-31 | Schering Corporation | Indoles in treatment of peptic ulcers |
| EP0299076A4 (en) * | 1987-01-23 | 1991-01-09 | Yoshitomi Pharmaceutical Industries, Ltd. | 5-hydroxyindole-3-carboxamide compound and medicinal use thereof |
| US5145845A (en) * | 1991-05-14 | 1992-09-08 | Warner-Lambert Co. | Substituted 2-carboxylindoles having pharmaceutical activity |
| IL109311A0 (en) * | 1993-04-16 | 1994-07-31 | Lilly Co Eli | 1H-indole-3-acetamide sPla2 inhibitors |
-
1994
- 1994-04-12 IL IL10931194A patent/IL109311A0/xx unknown
- 1994-04-13 HU HU9401060A patent/HUT70836A/hu unknown
- 1994-04-13 NZ NZ260298A patent/NZ260298A/en unknown
- 1994-04-13 TW TW083103301A patent/TW268942B/zh active
- 1994-04-14 BR BR9401482A patent/BR9401482A/pt not_active Application Discontinuation
- 1994-04-14 CA CA002121323A patent/CA2121323A1/en not_active Abandoned
- 1994-04-14 ES ES94302666T patent/ES2138648T3/es not_active Expired - Lifetime
- 1994-04-14 DK DK94302666T patent/DK0620215T3/da active
- 1994-04-14 CZ CZ1994893A patent/CZ289750B6/cs not_active IP Right Cessation
- 1994-04-14 DE DE69420068T patent/DE69420068T2/de not_active Expired - Fee Related
- 1994-04-14 AT AT94302666T patent/ATE183503T1/de not_active IP Right Cessation
- 1994-04-14 CO CO94014981A patent/CO4230092A1/es unknown
- 1994-04-14 EP EP94302666A patent/EP0620215B1/en not_active Expired - Lifetime
- 1994-04-15 KR KR1019940007935A patent/KR100317755B1/ko not_active Expired - Fee Related
- 1994-04-15 AU AU59492/94A patent/AU676884B2/en not_active Ceased
- 1994-04-15 FI FI941767A patent/FI941767A7/fi unknown
- 1994-04-15 UA UA94005180A patent/UA44218C2/uk unknown
- 1994-04-15 CN CN94104434A patent/CN1068588C/zh not_active Expired - Fee Related
- 1994-04-15 PL PL94303028A patent/PL181319B1/pl unknown
- 1994-04-15 NO NO941361A patent/NO300732B1/no not_active IP Right Cessation
- 1994-04-15 RU RU94012930/04A patent/RU2162463C2/ru active
- 1994-04-15 JP JP6077650A patent/JPH0725850A/ja active Pending
- 1994-04-15 YU YU20194A patent/YU20194A/sh unknown
-
1995
- 1995-05-05 US US08/435,256 patent/US5684034A/en not_active Expired - Lifetime
-
1999
- 1999-11-08 GR GR990402875T patent/GR3031783T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CZ89394A3 (en) | 1994-12-15 |
| PL181319B1 (pl) | 2001-07-31 |
| KR100317755B1 (ko) | 2002-08-09 |
| DE69420068D1 (de) | 1999-09-23 |
| CO4230092A1 (es) | 1995-10-19 |
| ATE183503T1 (de) | 1999-09-15 |
| EP0620215B1 (en) | 1999-08-18 |
| FI941767L (fi) | 1994-10-17 |
| JPH0725850A (ja) | 1995-01-27 |
| BR9401482A (pt) | 1994-10-18 |
| CA2121323A1 (en) | 1994-10-17 |
| DE69420068T2 (de) | 1999-12-23 |
| CN1068588C (zh) | 2001-07-18 |
| NO300732B1 (no) | 1997-07-14 |
| US5684034A (en) | 1997-11-04 |
| TW268942B (show.php) | 1996-01-21 |
| ES2138648T3 (es) | 2000-01-16 |
| FI941767A7 (fi) | 1994-10-17 |
| DK0620215T3 (da) | 1999-12-06 |
| UA44218C2 (uk) | 2002-02-15 |
| YU20194A (sh) | 1997-09-30 |
| HUT70836A (en) | 1995-11-28 |
| NO941361L (no) | 1994-10-17 |
| CN1098715A (zh) | 1995-02-15 |
| AU5949294A (en) | 1994-10-20 |
| EP0620215A1 (en) | 1994-10-19 |
| RU2162463C2 (ru) | 2001-01-27 |
| NZ260298A (en) | 1996-05-28 |
| HU9401060D0 (en) | 1994-07-28 |
| GR3031783T3 (en) | 2000-02-29 |
| FI941767A0 (fi) | 1994-04-15 |
| AU676884B2 (en) | 1997-03-27 |
| CZ289750B6 (cs) | 2002-03-13 |
| NO941361D0 (no) | 1994-04-15 |
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