IL102758A - Glycosaminoglycanoid derivatives, their preparation and pharmaceutical compositions comprising them - Google Patents

Glycosaminoglycanoid derivatives, their preparation and pharmaceutical compositions comprising them

Info

Publication number
IL102758A
IL102758A IL102758A IL10275892A IL102758A IL 102758 A IL102758 A IL 102758A IL 102758 A IL102758 A IL 102758A IL 10275892 A IL10275892 A IL 10275892A IL 102758 A IL102758 A IL 102758A
Authority
IL
Israel
Prior art keywords
sulfate
preparation
pharmaceutical compositions
groups
oalk
Prior art date
Application number
IL102758A
Other languages
English (en)
Other versions
IL102758A0 (en
Original Assignee
Akzo Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nv filed Critical Akzo Nv
Publication of IL102758A0 publication Critical patent/IL102758A0/xx
Publication of IL102758A publication Critical patent/IL102758A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/08—Polyoxyalkylene derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL102758A 1991-08-23 1992-08-07 Glycosaminoglycanoid derivatives, their preparation and pharmaceutical compositions comprising them IL102758A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP91402299 1991-08-23

Publications (2)

Publication Number Publication Date
IL102758A0 IL102758A0 (en) 1993-01-31
IL102758A true IL102758A (en) 1997-03-18

Family

ID=8208605

Family Applications (1)

Application Number Title Priority Date Filing Date
IL102758A IL102758A (en) 1991-08-23 1992-08-07 Glycosaminoglycanoid derivatives, their preparation and pharmaceutical compositions comprising them

Country Status (19)

Country Link
EP (1) EP0529715B1 (de)
JP (1) JP3048198B2 (de)
KR (1) KR100274115B1 (de)
AT (1) ATE149504T1 (de)
AU (1) AU656610B2 (de)
BR (1) BR1100632A (de)
CA (1) CA2076063C (de)
DE (1) DE69217774T2 (de)
DK (1) DK0529715T3 (de)
ES (1) ES2101026T3 (de)
FI (1) FI111726B (de)
GR (1) GR3023580T3 (de)
HK (1) HK1002032A1 (de)
HU (2) HUT62594A (de)
IL (1) IL102758A (de)
NO (1) NO179452C (de)
NZ (1) NZ244057A (de)
TW (1) TW213470B (de)
ZA (1) ZA926029B (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE179712T1 (de) * 1993-03-01 1999-05-15 Glycan Pharm Inc Analoge für spezifische oligosaccharid-protein- wechselwirkungen und ihre verwendungen
FR2704226B1 (fr) * 1993-04-22 1995-07-21 Sanofi Elf 3-desoxy oligosaccharides, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
IL120722A (en) * 1996-05-08 1999-07-14 Akzo Nobel Nv Polysulfated tetrasaccharide derivatives and pharmaceutical compositions containing them
FR2751334B1 (fr) 1996-07-19 1998-10-16 Sanofi Sa Polysaccharides synthetiques, procede pour leur preparation et compositions pharmaceutiques les contenant
IL126893A (en) 1997-11-19 2003-05-29 Akzo Nobel Nv Sulfated pentasaccharide derivatives and pharmaceutical compositions containing them
FR2773801B1 (fr) * 1998-01-19 2000-05-12 Sanofi Sa Nouveaux pentasaccharides, procedes pour leurs preparations et compositions pharmaceutiques les contenant
US6083933A (en) * 1999-04-19 2000-07-04 Stellar International Inc. Treatment of cystitis-like symptoms with chondroitin sulfate following administration of a challenge solution
FR2814463B1 (fr) * 2000-09-22 2002-11-15 Sanofi Synthelabo Nouveaux polysaccharides a activite antithrombotique comprenant au moins une liaison covalente avec la biotine ou un derive de la biotine
AU2002243630A1 (en) 2001-01-23 2002-08-06 Massachusetts Institute Of Technology Solid- and solution -phase synthesis of heparin and other glycosaminoglycans
PT1569912E (pt) 2002-12-03 2015-09-15 Pharmacyclics Llc Derivados 2-(2-hidroxibifenil-3-il)-1h-benzoimidazole-5- carboxamidina como inibidores do fator viia
US20040161476A1 (en) 2003-02-19 2004-08-19 Hahn Sungtack Samuel Cystitis treatment with high dose chondroitin sulfate
EP1778709B1 (de) 2004-08-05 2008-05-28 IVAX Drug Research Institute Ltd Polysulfatierte glykoside und salze davon
FR2874924B1 (fr) 2004-09-09 2006-12-01 Sanofi Aventis Sa Hexadecasaccharides biotinyles, leur preparation et leur utilisation therapeutique
TWI403334B (zh) 2004-12-23 2013-08-01 Merck Sharp & Dohme 包含生物素殘基之抗血栓雙重抑制劑
TWI376234B (en) 2005-02-01 2012-11-11 Msd Oss Bv Conjugates of a polypeptide and an oligosaccharide
CN102046781A (zh) 2008-05-30 2011-05-04 动量制药公司 糖结构以及制造和使用此类结构的方法
FR2938541B1 (fr) * 2008-11-20 2011-08-26 Sanofi Aventis Pentasaccharide cristallise,son procede d'obtention et son utilisation pour la preparation d'idraparinux
FR2949115B1 (fr) 2009-08-14 2012-11-02 Sanofi Aventis OLIGOSACCHARIDES N-SULFATES ACTIVATEURS DES RECEPTEURS DES FGFs, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
FR2949114B1 (fr) 2009-08-14 2011-08-26 Sanofi Aventis OCTASACCHARIDES N-ACYLES ACTIVATEURS DES RECEPTEURS DES FGFs, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
JP2013537181A (ja) 2010-09-10 2013-09-30 サノフイ 抗血栓活性及び改善された代謝安定性を有するビオチン化多糖類
FR2970969B1 (fr) 2011-01-27 2013-10-18 Sanofi Aventis Oligosaccharides 3-o-alkyles activateurs des recepteurs des fgfs, leur preparation et leur application en therapeutique
EP2578594A1 (de) 2011-10-04 2013-04-10 Sanofi Verfahren zur Herstellung von L-Iduronsäure mittels einer Decarboxylierung/intramolekulare Zyklisierungs-Tandemreaktion
WO2023062386A1 (en) * 2021-10-14 2023-04-20 Owlstone Medical Limited Method for the synthesis of evoc probes

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3017407A (en) * 1958-08-18 1962-01-16 Riker Laboratories Inc Process for producing polysulfuric acid esters of polysaccharides
GB1110939A (en) * 1965-10-06 1968-04-24 Meito Sangyo Kk Sulphuric acid esters of disaccharides and hexitols,and their use as antipeptic ulcer agents
HU172937B (hu) * 1975-12-18 1979-01-28 Chinoin Gyogyszer Es Vegyeszet Sposob poluchenija novykh proizvodnykh khondroitin-sernoj kisloty s mestno anestezirujuhhim ehffektom
US4818816A (en) * 1981-04-28 1989-04-04 Choay, S.A. Process for the organic synthesis of oligosaccharides and derivatives thereof
FR2543145B1 (fr) * 1983-03-24 1986-10-17 Sanofi Sa Nouveaux sulfates de xylanes, leur procede de preparation et leur activite anti-thrombotique et hypolipemiante
AU607690B2 (en) * 1985-12-24 1991-03-14 Marion Laboratories, Inc. Use of synthetic sulfated saccharides to enhance wound healing
EP0300099A1 (de) * 1987-07-20 1989-01-25 Akzo N.V. Pentasaccharide
ES2060284T3 (es) * 1990-04-23 1994-11-16 Sanofi Elf Un procedimiento para la preparacion de un derivado de carbohidrato que comprende una unidad de trisacarido.
EP2301618B1 (de) * 2009-09-23 2011-12-07 Covidien AG Dilatationsvorrichtung zum Dilatieren einer Öffnung

Also Published As

Publication number Publication date
FI923726A0 (fi) 1992-08-19
ZA926029B (en) 1993-03-10
FI923726A (fi) 1993-02-24
CA2076063A1 (en) 1993-02-24
HU211738A9 (en) 1995-12-28
AU2121892A (en) 1993-02-25
HK1002032A1 (en) 1998-07-24
GR3023580T3 (en) 1997-08-29
FI111726B (fi) 2003-09-15
NO923297L (no) 1993-02-24
IL102758A0 (en) 1993-01-31
NO923297D0 (no) 1992-08-21
AU656610B2 (en) 1995-02-09
JPH05194602A (ja) 1993-08-03
ATE149504T1 (de) 1997-03-15
TW213470B (de) 1993-09-21
HUT62594A (en) 1993-05-28
CA2076063C (en) 2003-12-30
BR1100632A (pt) 2000-06-13
DK0529715T3 (da) 1997-09-08
DE69217774T2 (de) 1997-06-26
EP0529715B1 (de) 1997-03-05
JP3048198B2 (ja) 2000-06-05
DE69217774D1 (de) 1997-04-10
ES2101026T3 (es) 1997-07-01
KR930004324A (ko) 1993-03-22
KR100274115B1 (ko) 2000-12-15
NO179452B (no) 1996-07-01
NO179452C (no) 1996-10-09
EP0529715A1 (de) 1993-03-03
NZ244057A (en) 1995-05-26

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
HCA Change of name of proprietor(s) after amalgamation
KB Patent renewed
KB Patent renewed
EXP Patent expired