ES486556A1 - Procedimiento de preparacion de nuevos poli (h-) sulfatos derutina y sales de los mismos - Google Patents

Procedimiento de preparacion de nuevos poli (h-) sulfatos derutina y sales de los mismos

Info

Publication number
ES486556A1
ES486556A1 ES486556A ES486556A ES486556A1 ES 486556 A1 ES486556 A1 ES 486556A1 ES 486556 A ES486556 A ES 486556A ES 486556 A ES486556 A ES 486556A ES 486556 A1 ES486556 A1 ES 486556A1
Authority
ES
Spain
Prior art keywords
sulfates
preparation
pharmaceutical compositions
compositions containing
rutin poly
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES486556A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of ES486556A1 publication Critical patent/ES486556A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/06—Benzopyran radicals
    • C07H17/065—Benzo[b]pyrans
    • C07H17/07—Benzo[b]pyran-4-ones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

Procedimiento para la preparación de nuevos poli (H-) sulfatos de rutina y sales de los mismos de fórmula: **(formula)** en donde R se selecciona del grupo que consiste en hidrógeno y -30 3A; en donde A es un catión de sal farmaceuticamente aceptable; con la condición de que por lo menos seis de los grupos R son -SO 3A; caracterizado porque comprende hacer reaccionar rutina en un solvente apropiado con un complejo de trialquilamina-trioxido de azufre a 50º -90º C, aislar la sal de sulfato de trialquilamina, seguido por tratamiento con un acetato de metal alcalino en solución acuosa.
ES486556A 1978-12-04 1979-12-03 Procedimiento de preparacion de nuevos poli (h-) sulfatos derutina y sales de los mismos Expired ES486556A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US96642378A 1978-12-04 1978-12-04
US6258779A 1979-07-31 1979-07-31

Publications (1)

Publication Number Publication Date
ES486556A1 true ES486556A1 (es) 1980-09-16

Family

ID=26742453

Family Applications (1)

Application Number Title Priority Date Filing Date
ES486556A Expired ES486556A1 (es) 1978-12-04 1979-12-03 Procedimiento de preparacion de nuevos poli (h-) sulfatos derutina y sales de los mismos

Country Status (12)

Country Link
EP (1) EP0013470B1 (es)
KR (1) KR830001687B1 (es)
AR (1) AR221383A1 (es)
AU (1) AU530460B2 (es)
CA (1) CA1139749A (es)
DD (1) DD147544A5 (es)
DE (1) DE2965524D1 (es)
DK (1) DK513479A (es)
ES (1) ES486556A1 (es)
IL (1) IL58513A (es)
PL (1) PL220109A1 (es)
YU (1) YU285579A (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0075626A1 (en) * 1981-09-29 1983-04-06 American Cyanamid Company Novel rutin nona- and deca(H-)sulfate salts, methods of preparing novel salts, and use of novel salts of complement inhibitors
US4708949A (en) * 1985-09-24 1987-11-24 Yaguang Liu Therapeutic composition from plant extracts
IT1245371B (it) * 1991-03-28 1994-09-20 Geymonat Spa Derivati di flavoni, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono
ES2041216B1 (es) * 1992-02-25 1994-06-16 Espanola Prod Quimicos Procedimiento de preparacion de un nuevo derivado sulfatado de diosmina.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2043455A1 (en) * 1969-05-02 1971-02-19 Melle Usine De Water soluble propylsulphonates of rutin
DE1956016A1 (de) * 1969-11-07 1971-05-13 Blendax Werke Schneider Co Praeparat zur Zahn- und Mundpflege

Also Published As

Publication number Publication date
DD147544A5 (de) 1981-04-08
KR830001308A (ko) 1983-04-30
KR830001687B1 (ko) 1983-08-29
AU530460B2 (en) 1983-07-14
EP0013470B1 (en) 1983-05-25
AU5202579A (en) 1980-06-12
PL220109A1 (es) 1981-10-16
DE2965524D1 (en) 1983-07-07
IL58513A0 (en) 1980-01-31
AR221383A1 (es) 1981-01-30
CA1139749A (en) 1983-01-18
EP0013470A1 (en) 1980-07-23
DK513479A (da) 1980-06-05
YU285579A (en) 1983-02-28
IL58513A (en) 1982-11-30

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