IL102453A - 2-(2-substituted pyrrolidinylthio) carbapenem derivatives process for their preparation and pharmaceutical compositions containing them - Google Patents

2-(2-substituted pyrrolidinylthio) carbapenem derivatives process for their preparation and pharmaceutical compositions containing them

Info

Publication number
IL102453A
IL102453A IL10245392A IL10245392A IL102453A IL 102453 A IL102453 A IL 102453A IL 10245392 A IL10245392 A IL 10245392A IL 10245392 A IL10245392 A IL 10245392A IL 102453 A IL102453 A IL 102453A
Authority
IL
Israel
Prior art keywords
group
methyl
carbapen
hydroxyethyl
atom
Prior art date
Application number
IL10245392A
Other languages
English (en)
Other versions
IL102453A0 (en
Original Assignee
Banyu Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Banyu Pharma Co Ltd filed Critical Banyu Pharma Co Ltd
Publication of IL102453A0 publication Critical patent/IL102453A0/xx
Publication of IL102453A publication Critical patent/IL102453A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL10245392A 1991-07-09 1992-07-09 2-(2-substituted pyrrolidinylthio) carbapenem derivatives process for their preparation and pharmaceutical compositions containing them IL102453A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP19476791 1991-07-09
JP34959191 1991-12-07

Publications (2)

Publication Number Publication Date
IL102453A0 IL102453A0 (en) 1993-01-14
IL102453A true IL102453A (en) 1996-01-19

Family

ID=26508721

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10245392A IL102453A (en) 1991-07-09 1992-07-09 2-(2-substituted pyrrolidinylthio) carbapenem derivatives process for their preparation and pharmaceutical compositions containing them

Country Status (12)

Country Link
EP (1) EP0522504A1 (fr)
KR (1) KR930702353A (fr)
AU (1) AU646577B2 (fr)
CA (1) CA2073377A1 (fr)
CZ (1) CZ214492A3 (fr)
FI (1) FI931015A0 (fr)
IE (1) IE922225A1 (fr)
IL (1) IL102453A (fr)
NO (1) NO930844L (fr)
TW (1) TW206226B (fr)
WO (1) WO1993001192A1 (fr)
YU (1) YU68292A (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9216102D0 (en) * 1992-07-29 1992-09-09 Smithkline Beecham Plc Pharmaceutical substances
KR950014111A (ko) * 1993-11-23 1995-06-15 유충식 새로운 카바페넴 유도체 및 그 제조방법
KR970010769A (ko) * 1995-08-01 1997-03-27 유충식 카바페넴 유도체의 제조방법

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0182213B1 (fr) * 1984-11-08 1990-09-26 Sumitomo Pharmaceuticals Company, Limited Dérivés de carbapénème et leur préparatIon
AU631671B2 (en) * 1989-08-04 1992-12-03 Banyu Pharmaceutical Co., Ltd. 2-(2-vinylpyrrolidinylthio)carbapenem derivatives

Also Published As

Publication number Publication date
IE922225A1 (en) 1993-01-13
AU1947192A (en) 1993-01-14
AU646577B2 (en) 1994-02-24
FI931015A7 (fi) 1993-03-08
KR930702353A (ko) 1993-09-08
EP0522504A1 (fr) 1993-01-13
TW206226B (fr) 1993-05-21
NO930844D0 (no) 1993-03-08
YU68292A (sh) 1995-03-27
IL102453A0 (en) 1993-01-14
WO1993001192A1 (fr) 1993-01-21
CZ214492A3 (en) 1993-01-13
NO930844L (no) 1993-05-07
CA2073377A1 (fr) 1993-01-10
FI931015A0 (fi) 1993-03-08

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Legal Events

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FF Patent granted
RH Patent void