IL102355A0 - N-phenylthiourea derivatives,their preparation and pharmaceutical compositions containing them - Google Patents
N-phenylthiourea derivatives,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL102355A0 IL102355A0 IL102355A IL10235592A IL102355A0 IL 102355 A0 IL102355 A0 IL 102355A0 IL 102355 A IL102355 A IL 102355A IL 10235592 A IL10235592 A IL 10235592A IL 102355 A0 IL102355 A0 IL 102355A0
- Authority
- IL
- Israel
- Prior art keywords
- pharmaceutical compositions
- preparation
- compositions containing
- compounds
- subgroup
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C335/04—Derivatives of thiourea
- C07C335/16—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Vascular Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
- Saccharide Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Footwear And Its Accessory, Manufacturing Method And Apparatuses (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US72400191A | 1991-07-01 | 1991-07-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL102355A0 true IL102355A0 (en) | 1993-01-14 |
Family
ID=24908548
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL102355A IL102355A0 (en) | 1991-07-01 | 1992-06-29 | N-phenylthiourea derivatives,their preparation and pharmaceutical compositions containing them |
Country Status (24)
| Country | Link |
|---|---|
| EP (1) | EP0528146B1 (da) |
| JP (1) | JPH05221959A (da) |
| KR (1) | KR930002311A (da) |
| AT (1) | ATE134364T1 (da) |
| AU (1) | AU657141B2 (da) |
| CA (1) | CA2072704A1 (da) |
| CZ (1) | CZ204692A3 (da) |
| DE (1) | DE69208408T2 (da) |
| DK (1) | DK0528146T3 (da) |
| ES (1) | ES2083625T3 (da) |
| FI (1) | FI923033A (da) |
| GR (1) | GR3019785T3 (da) |
| HK (1) | HK73196A (da) |
| HU (1) | HUT62558A (da) |
| IE (1) | IE73488B1 (da) |
| IL (1) | IL102355A0 (da) |
| MX (1) | MX9203838A (da) |
| NO (1) | NO922564L (da) |
| NZ (1) | NZ243352A (da) |
| RO (1) | RO111933B1 (da) |
| RU (1) | RU2087467C1 (da) |
| SK (1) | SK204692A3 (da) |
| TW (1) | TW213448B (da) |
| ZA (1) | ZA924823B (da) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU5170698A (en) * | 1996-11-14 | 1998-06-03 | American Home Products Corporation | Substituted tetrahydro-1,3,5-triazin-2{1h}-thiones as anti-atherosclerotic agents |
| WO1998033775A1 (en) * | 1997-02-03 | 1998-08-06 | American Home Products Corporation | 2-substituted-1-acyl-1,2-dihydroquinoline derivatives to increase hdl-cholesterol level |
| WO1998057926A1 (en) * | 1997-06-16 | 1998-12-23 | American Home Products Corporation | Elevation of hdl cholesterol by n-[2-[ (aminothioxomethyl)hydrazono] -2-arylethyl]amides |
| US6011053A (en) * | 1997-08-01 | 2000-01-04 | American Home Products Corporation | Substituted indole-1-carbothioic acid amides as novel antiatherosclerotic agents |
| WO1999011618A1 (en) * | 1997-09-03 | 1999-03-11 | American Home Products Corporation | Substituted indole-1-carbothioic acid amides as novel antiatherosclerotic agents |
| US6455566B1 (en) | 1997-09-03 | 2002-09-24 | Wyeth | Substituted 1-aryl-3-heteroaryl-thioureas (or isothioureas) as antiatherosclerotic agents |
| TW415942B (en) * | 1997-09-03 | 2000-12-21 | American Home Prod | Novel substituted 1-aryl-3-heteroaryl-thioureas and substituted 1-aryl-3-heteroaryl-isothioureas as antiatherosclerotic agents |
| WO1999011621A2 (en) * | 1997-09-03 | 1999-03-11 | American Home Products Corporation | Thiourea for increasing hdl-cholesterol levels, which are useful as anti-atherosclerotic agents |
| DE10017881A1 (de) * | 2000-04-11 | 2001-10-25 | Bayer Ag | Wirkstoffkombinationen mit insektiziden und akariziden Eigenschaften |
| WO2002016319A1 (en) | 2000-08-21 | 2002-02-28 | Pacific Corporation | Novel thiourea compounds and the pharmaceutical compositions containing the same |
| DE60133743T2 (de) | 2000-08-21 | 2009-07-02 | Pacific Corp. | Neue thiourea-derivate und pharmazeutische zusammensetzungen die diese enthalten |
| US6472430B2 (en) | 2000-10-02 | 2002-10-29 | Hassan M. Elokdah | Amino thioxomethyl amino oxyacetic acid derivatives |
| EP1426046A4 (en) | 2001-09-14 | 2005-11-02 | Shionogi & Co | NEW USE OF TRICYCLIC COMPOUNDS |
| US7429593B2 (en) | 2001-09-14 | 2008-09-30 | Shionogi & Co., Ltd. | Utilities of amide compounds |
| US8124625B2 (en) | 2001-09-14 | 2012-02-28 | Shionogi & Co., Ltd. | Method of enhancing the expression of apolipoprotein AI using olefin derivatives |
| ES2362770B1 (es) * | 2009-12-24 | 2012-05-22 | Universidad De Sevilla | Uso de compuesto n-fenil-n'-(3-metil-2-butenil)tiourea para la elaboración de medicamentos destinados al tratamiento de la encefalopatía hepática. |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3950537A (en) * | 1973-06-29 | 1976-04-13 | Rohm And Haas Company | Gastrointestinally active thioureas |
| IL67417A (en) * | 1982-01-26 | 1989-10-31 | American Cyanamid Co | Antiatherosclerotic substituted ureas,process for their preparation and pharmaceutical compositions containing them |
| JPH0193569A (ja) * | 1987-07-02 | 1989-04-12 | Warner Lambert Co | アシル‐ＣｏＡ：コレステロールアシルトランスフエラーゼのＮ‐〔（２，６‐ジ置換）フエニル〕尿素およびカルバメート阻害剤 |
| US5116848A (en) * | 1988-03-30 | 1992-05-26 | Warner-Lambert Company | N-(((2,6-disubstituted)phenyl)-n-diarylalkyl)ureas as antihyperlipidemic and antiatherosclerotic agents |
| GB8908063D0 (en) * | 1989-04-11 | 1989-05-24 | Beecham Group Plc | Novel compounds |
| JPH0395153A (ja) * | 1989-06-15 | 1991-04-19 | Mitsubishi Kasei Corp | ジフェニル尿素誘導体 |
-
1992
- 1992-06-18 HU HU9202047A patent/HUT62558A/hu unknown
- 1992-06-29 AU AU18677/92A patent/AU657141B2/en not_active Ceased
- 1992-06-29 KR KR1019920011449A patent/KR930002311A/ko not_active Application Discontinuation
- 1992-06-29 IL IL102355A patent/IL102355A0/xx unknown
- 1992-06-29 ES ES92110945T patent/ES2083625T3/es not_active Expired - Lifetime
- 1992-06-29 DK DK92110945.0T patent/DK0528146T3/da active
- 1992-06-29 DE DE69208408T patent/DE69208408T2/de not_active Expired - Fee Related
- 1992-06-29 NO NO92922564A patent/NO922564L/no unknown
- 1992-06-29 EP EP92110945A patent/EP0528146B1/en not_active Expired - Lifetime
- 1992-06-29 JP JP4192818A patent/JPH05221959A/ja active Pending
- 1992-06-29 NZ NZ243352A patent/NZ243352A/en unknown
- 1992-06-29 CA CA002072704A patent/CA2072704A1/en not_active Abandoned
- 1992-06-29 RO RO92-0886A patent/RO111933B1/ro unknown
- 1992-06-29 AT AT92110945T patent/ATE134364T1/de not_active IP Right Cessation
- 1992-06-29 ZA ZA924823A patent/ZA924823B/xx unknown
- 1992-06-30 MX MX9203838A patent/MX9203838A/es unknown
- 1992-06-30 CZ CS922046A patent/CZ204692A3/cs unknown
- 1992-06-30 FI FI923033A patent/FI923033A/fi not_active Application Discontinuation
- 1992-06-30 RU SU925052139A patent/RU2087467C1/ru active
- 1992-06-30 SK SK2046-92A patent/SK204692A3/sk unknown
- 1992-07-01 IE IE922132A patent/IE73488B1/en not_active IP Right Cessation
- 1992-07-04 TW TW081105311A patent/TW213448B/zh active
-
1996
- 1996-04-25 HK HK73196A patent/HK73196A/xx not_active IP Right Cessation
- 1996-04-29 GR GR960401165T patent/GR3019785T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATE134364T1 (de) | 1996-03-15 |
| FI923033A (fi) | 1993-01-02 |
| DE69208408D1 (de) | 1996-03-28 |
| DK0528146T3 (da) | 1996-05-06 |
| CA2072704A1 (en) | 1993-01-02 |
| HU9202047D0 (en) | 1992-09-28 |
| ES2083625T3 (es) | 1996-04-16 |
| TW213448B (da) | 1993-09-21 |
| NO922564L (no) | 1993-01-04 |
| HK73196A (en) | 1996-05-03 |
| CZ204692A3 (en) | 1993-01-13 |
| HUT62558A (en) | 1993-05-28 |
| RU2087467C1 (ru) | 1997-08-20 |
| RO111933B1 (ro) | 1997-03-31 |
| ZA924823B (en) | 1993-12-29 |
| IE922132A1 (en) | 1993-01-13 |
| SK204692A3 (en) | 1995-02-08 |
| NZ243352A (en) | 1995-02-24 |
| JPH05221959A (ja) | 1993-08-31 |
| MX9203838A (es) | 1993-01-01 |
| NO922564D0 (no) | 1992-06-29 |
| GR3019785T3 (en) | 1996-07-31 |
| DE69208408T2 (de) | 1996-07-18 |
| AU1867792A (en) | 1993-01-07 |
| IE73488B1 (en) | 1997-06-04 |
| FI923033A0 (fi) | 1992-06-30 |
| EP0528146A1 (en) | 1993-02-24 |
| KR930002311A (ko) | 1993-02-22 |
| EP0528146B1 (en) | 1996-02-21 |
| AU657141B2 (en) | 1995-03-02 |
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