IE55184B1 - Preparation of 6a,10a-trans-hexahydrodibenzopyranones - Google Patents

Preparation of 6a,10a-trans-hexahydrodibenzopyranones

Info

Publication number
IE55184B1
IE55184B1 IE1115/83A IE111583A IE55184B1 IE 55184 B1 IE55184 B1 IE 55184B1 IE 1115/83 A IE1115/83 A IE 1115/83A IE 111583 A IE111583 A IE 111583A IE 55184 B1 IE55184 B1 IE 55184B1
Authority
IE
Ireland
Prior art keywords
formula
trans
compound
methoxy
methyl
Prior art date
Application number
IE1115/83A
Other languages
English (en)
Other versions
IE831115L (en
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of IE831115L publication Critical patent/IE831115L/xx
Publication of IE55184B1 publication Critical patent/IE55184B1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78Ring systems having three or more relevant rings
    • C07D311/80Dibenzopyrans; Hydrogenated dibenzopyrans

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Fats And Perfumes (AREA)
  • Pyrane Compounds (AREA)
IE1115/83A 1982-05-24 1983-05-13 Preparation of 6a,10a-trans-hexahydrodibenzopyranones IE55184B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/381,111 US4395560A (en) 1982-05-24 1982-05-24 Preparation of 6a,10a-trans-hexahydrodibenzopyranones

Publications (2)

Publication Number Publication Date
IE831115L IE831115L (en) 1983-11-24
IE55184B1 true IE55184B1 (en) 1990-06-20

Family

ID=23503705

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1115/83A IE55184B1 (en) 1982-05-24 1983-05-13 Preparation of 6a,10a-trans-hexahydrodibenzopyranones

Country Status (12)

Country Link
US (1) US4395560A (enExample)
EP (1) EP0096480B1 (enExample)
JP (1) JPS58210079A (enExample)
KR (1) KR860001030B1 (enExample)
CA (1) CA1188702A (enExample)
DE (1) DE3378119D1 (enExample)
DK (1) DK210083A (enExample)
GB (1) GB2121038B (enExample)
GR (1) GR79272B (enExample)
HU (1) HU193651B (enExample)
IE (1) IE55184B1 (enExample)
IL (1) IL68626A (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2340445A1 (en) * 1998-05-04 1999-11-11 The University Of Connecticut Novel analgesic and immunomodulatory cannabinoids
US7897598B2 (en) * 1998-06-09 2011-03-01 Alexandros Makriyannis Inhibitors of the anandamide transporter
US7589220B2 (en) * 1998-06-09 2009-09-15 University Of Connecticut Inhibitors of the anandamide transporter
US7161016B1 (en) 1998-11-24 2007-01-09 University Of Connecticut Cannabimimetic lipid amides as useful medications
US7276613B1 (en) 1998-11-24 2007-10-02 University Of Connecticut Retro-anandamides, high affinity and stability cannabinoid receptor ligands
EP1223808B1 (en) 1999-10-18 2007-03-07 The University Of Connecticut Peripheral cannabinoid receptor (cb2) selective ligands
US8084467B2 (en) * 1999-10-18 2011-12-27 University Of Connecticut Pyrazole derivatives as cannabinoid receptor antagonists
US7741365B2 (en) * 1999-10-18 2010-06-22 University Of Connecticut Peripheral cannabinoid receptor (CB2) selective ligands
US7393842B2 (en) * 2001-08-31 2008-07-01 University Of Connecticut Pyrazole analogs acting on cannabinoid receptors
US6943266B1 (en) * 1999-10-18 2005-09-13 University Of Connecticut Bicyclic cannabinoid agonists for the cannabinoid receptor
US7119108B1 (en) * 1999-10-18 2006-10-10 University Of Connecticut Pyrazole derivatives as cannabinoid receptor antagonists
US6900236B1 (en) * 1999-10-18 2005-05-31 University Of Connecticut Cannabimimetic indole derivatives
JP2004532185A (ja) * 2001-01-26 2004-10-21 ユニバーシティ オブ コネチカット 新規なカンナビミメティックリガンド
ATE478670T1 (de) 2001-01-29 2010-09-15 Univ Connecticut Rezeptor-selektive cannabimimetische aminoalkylindole
JP4312594B2 (ja) * 2001-07-13 2009-08-12 ユニバーシティ オブ コネチカット 新規な二環式及び三環式カンナビノイド
CA2464333C (en) * 2001-10-26 2011-07-26 University Of Connecticut Heteroindanes: a new class of potent cannabimimetic ligands
JP2006511460A (ja) 2002-08-23 2006-04-06 ユニバーシティ オブ コネチカット 治療適応を持つケトカンナビノイド
CA2638940C (en) * 2008-08-28 2009-09-15 Dalton Chemical Laboratories Inc. Improved synthesis of hexahydrodibenzopyranones

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4054583A (en) * 1976-07-06 1977-10-18 Eli Lilly And Company Process for converting 2,7-dihydroxy-5-isopropylidene-9-substituted-2,6-methano-3,4,5,6-tetrahydro-2H-1-benzoxocin to trans-1-hydroxy-3-substituted-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9H-dibenzo(b,d)pyran-9-one
US4054582A (en) * 1976-07-06 1977-10-18 Eli Lilly And Company Process for converting cis-hexahydrodibenzo[b,d]pyran-9-ones to trans-hexahydrodibenzo[b,d]-pyran-9-ones
CA1096390A (en) * 1976-07-06 1981-02-24 Edward R. Lavagnino PROCESS FOR PREPARING DL-CIS-1-HYDROXY-3-SUBSTITUTED- 6,6-DIMETHYL-6,6.alpha.,7,8,10,10.alpha.-HEXAHYDRO-9H- DIBENZO(B,D,)PYRAN-9-ONES
PT66744B (en) * 1976-07-06 1978-11-27 Lilly Co Eli Process for preparing cis-hexahydrodibenzopyranones
US4054581A (en) * 1976-07-06 1977-10-18 Eli Lilly And Company Preparation of cis-1-hydroxy-3-substituted-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9H-dibenzo[b,d]pyran-9-ones and intermediates therefor
GB1582564A (en) * 1976-07-06 1981-01-14 Lilly Co Eli Dibenzopyrans
US4171315A (en) * 1978-03-31 1979-10-16 Eli Lilly And Company Preparation of cis-hexahydrodibenzopyranones

Also Published As

Publication number Publication date
JPS58210079A (ja) 1983-12-07
DK210083A (da) 1983-11-25
GB2121038B (en) 1986-01-22
GB2121038A (en) 1983-12-14
HU193651B (en) 1987-11-30
EP0096480B1 (en) 1988-09-28
KR860001030B1 (ko) 1986-07-28
GR79272B (enExample) 1984-05-20
IE831115L (en) 1983-11-24
EP0096480A3 (en) 1985-04-03
GB8313470D0 (en) 1983-06-22
US4395560A (en) 1983-07-26
IL68626A0 (en) 1983-09-30
KR840004737A (ko) 1984-10-24
DK210083D0 (da) 1983-05-11
DE3378119D1 (en) 1988-11-03
EP0096480A2 (en) 1983-12-21
CA1188702A (en) 1985-06-11
IL68626A (en) 1986-12-31

Similar Documents

Publication Publication Date Title
IE55184B1 (en) Preparation of 6a,10a-trans-hexahydrodibenzopyranones
Saito et al. Synthetic studies of proanthocyanidins. Part 2: Stereoselective gram-scale synthesis of procyanidin-B3
IE45247B1 (en) The preparation of optically active hexahydro dibenzo pyranones from novel optically active norpinanones
EP0004753B1 (en) Preparation of tetrahydrobenzoxocins and cis-hexahydrodibenzopyranones
US4208351A (en) Stereoselective preparation of hexahydro dibenzopyranones and intermediates therefor
US4176233A (en) Stereoselective preparation of hexahydro dibenzopyranones and intermediates therefor
US7126014B2 (en) Synthesis of epecatechin-4α, 8-epicatechin and -catechin dimers and derivatives thereof
US4645845A (en) Novel optically active chroman derivatives, their preparation and novel intermediates
US4140701A (en) 2,6-Methano-2H-1-benzoxocins
US4131614A (en) Process for preparing cis-hexahydrodibenzopyranones
EP0247035B1 (en) Optically active dl-nordihydroguaiaretic acid isomers and their racemates, process for preparing them and method of imparting a ple
US4075230A (en) Preparation of optically active trans-hexahydrodibenzopyranones
GB1582565A (en) Ketals of 4-(1-hydroxy-1-methylethyl)-3-cyclohexen-1-one and their use in preparing dibenzopyranone derivatives
JP3986606B2 (ja) ビタミンd誘導体のa環部分の合成に有用な合成中間体、その製造方法およびその使用方法
KR820002112B1 (ko) 시스-헥사 하이드로 디벤조 피라논의 제조방법
CA1097370A (en) Stereoselective preparation of hexahydro dibenzopyranones and intermediates therefor
KR810000429B1 (ko) 트랜스-헥사하이드로디벤조피라논의 제조방법
US5468869A (en) Process for production of (azolylmethyl)-(biphenylmethyl)cyclopentanol derivatives
KR820000076B1 (ko) dl-시스-1-하이드록시-3-치환-6.6-디메틸-6,6a,7,8,10,10a-헥사하이드로-9H-디벤조 [b,d] 피란-9-온의 제조방법
IL119561A (en) Substituted benzodioxane derivatives
KR820000784B1 (ko) 헥사하이드로-디벤조피라논 화합물의 광학적 이성체의 제조방법
AU654937B2 (en) Racemic nordihydroguaiaretic acid and intermediates
JP2510581B2 (ja) ベンゾハイドロキノン誘導体
JPH10204077A (ja) 抗酸化活性を有するベンゾクロマン誘導体
CS235544B2 (en) Method of new racemic aglycones production