GB2121038B - Preparation of 6a 10a-trans-hexahydrodibenzopyranones - Google Patents

Preparation of 6a 10a-trans-hexahydrodibenzopyranones

Info

Publication number
GB2121038B
GB2121038B GB08313470A GB8313470A GB2121038B GB 2121038 B GB2121038 B GB 2121038B GB 08313470 A GB08313470 A GB 08313470A GB 8313470 A GB8313470 A GB 8313470A GB 2121038 B GB2121038 B GB 2121038B
Authority
GB
United Kingdom
Prior art keywords
hexahydrodibenzopyranones
trans
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB08313470A
Other languages
English (en)
Other versions
GB2121038A (en
GB8313470D0 (en
Inventor
Charles Wilbur Ryan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of GB8313470D0 publication Critical patent/GB8313470D0/en
Publication of GB2121038A publication Critical patent/GB2121038A/en
Application granted granted Critical
Publication of GB2121038B publication Critical patent/GB2121038B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Fats And Perfumes (AREA)
  • Pyrane Compounds (AREA)
GB08313470A 1982-05-24 1983-05-16 Preparation of 6a 10a-trans-hexahydrodibenzopyranones Expired GB2121038B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/381,111 US4395560A (en) 1982-05-24 1982-05-24 Preparation of 6a,10a-trans-hexahydrodibenzopyranones

Publications (3)

Publication Number Publication Date
GB8313470D0 GB8313470D0 (en) 1983-06-22
GB2121038A GB2121038A (en) 1983-12-14
GB2121038B true GB2121038B (en) 1986-01-22

Family

ID=23503705

Family Applications (1)

Application Number Title Priority Date Filing Date
GB08313470A Expired GB2121038B (en) 1982-05-24 1983-05-16 Preparation of 6a 10a-trans-hexahydrodibenzopyranones

Country Status (12)

Country Link
US (1) US4395560A (enExample)
EP (1) EP0096480B1 (enExample)
JP (1) JPS58210079A (enExample)
KR (1) KR860001030B1 (enExample)
CA (1) CA1188702A (enExample)
DE (1) DE3378119D1 (enExample)
DK (1) DK210083A (enExample)
GB (1) GB2121038B (enExample)
GR (1) GR79272B (enExample)
HU (1) HU193651B (enExample)
IE (1) IE55184B1 (enExample)
IL (1) IL68626A (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010009965A1 (en) * 1998-05-04 2001-07-26 Alexandros Makriyannis Novel analgesic and immunomodulatory cannabinoids
US7589220B2 (en) * 1998-06-09 2009-09-15 University Of Connecticut Inhibitors of the anandamide transporter
US7897598B2 (en) * 1998-06-09 2011-03-01 Alexandros Makriyannis Inhibitors of the anandamide transporter
US7161016B1 (en) 1998-11-24 2007-01-09 University Of Connecticut Cannabimimetic lipid amides as useful medications
US7276613B1 (en) 1998-11-24 2007-10-02 University Of Connecticut Retro-anandamides, high affinity and stability cannabinoid receptor ligands
US7119108B1 (en) 1999-10-18 2006-10-10 University Of Connecticut Pyrazole derivatives as cannabinoid receptor antagonists
DE60033834T2 (de) 1999-10-18 2007-11-15 The University Of Connecticut, Farmington Für periphäre cannabinoid-rezeptoren selektive liganden
US7741365B2 (en) * 1999-10-18 2010-06-22 University Of Connecticut Peripheral cannabinoid receptor (CB2) selective ligands
US6943266B1 (en) 1999-10-18 2005-09-13 University Of Connecticut Bicyclic cannabinoid agonists for the cannabinoid receptor
US8084467B2 (en) * 1999-10-18 2011-12-27 University Of Connecticut Pyrazole derivatives as cannabinoid receptor antagonists
US7393842B2 (en) * 2001-08-31 2008-07-01 University Of Connecticut Pyrazole analogs acting on cannabinoid receptors
US6900236B1 (en) * 1999-10-18 2005-05-31 University Of Connecticut Cannabimimetic indole derivatives
WO2002058636A2 (en) * 2001-01-26 2002-08-01 University Of Connecticut Novel cannabimimetic ligands
EP1363632B1 (en) 2001-01-29 2010-08-25 The University of Connecticut Receptor selective cannabimimetic aminoalkylindoles
EP1414775B1 (en) * 2001-07-13 2012-12-19 The University of Connecticut Bicyclic cannabinoid
US7666867B2 (en) * 2001-10-26 2010-02-23 University Of Connecticut Heteroindanes: a new class of potent cannabimimetic ligands
JP2006511460A (ja) 2002-08-23 2006-04-06 ユニバーシティ オブ コネチカット 治療適応を持つケトカンナビノイド
CA2638940C (en) * 2008-08-28 2009-09-15 Dalton Chemical Laboratories Inc. Improved synthesis of hexahydrodibenzopyranones

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1096390A (en) * 1976-07-06 1981-02-24 Edward R. Lavagnino PROCESS FOR PREPARING DL-CIS-1-HYDROXY-3-SUBSTITUTED- 6,6-DIMETHYL-6,6.alpha.,7,8,10,10.alpha.-HEXAHYDRO-9H- DIBENZO(B,D,)PYRAN-9-ONES
US4054581A (en) * 1976-07-06 1977-10-18 Eli Lilly And Company Preparation of cis-1-hydroxy-3-substituted-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9H-dibenzo[b,d]pyran-9-ones and intermediates therefor
US4054583A (en) * 1976-07-06 1977-10-18 Eli Lilly And Company Process for converting 2,7-dihydroxy-5-isopropylidene-9-substituted-2,6-methano-3,4,5,6-tetrahydro-2H-1-benzoxocin to trans-1-hydroxy-3-substituted-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9H-dibenzo(b,d)pyran-9-one
GB1582564A (en) * 1976-07-06 1981-01-14 Lilly Co Eli Dibenzopyrans
PT66744B (en) * 1976-07-06 1978-11-27 Lilly Co Eli Process for preparing cis-hexahydrodibenzopyranones
US4054582A (en) * 1976-07-06 1977-10-18 Eli Lilly And Company Process for converting cis-hexahydrodibenzo[b,d]pyran-9-ones to trans-hexahydrodibenzo[b,d]-pyran-9-ones
US4171315A (en) * 1978-03-31 1979-10-16 Eli Lilly And Company Preparation of cis-hexahydrodibenzopyranones

Also Published As

Publication number Publication date
KR860001030B1 (ko) 1986-07-28
IE55184B1 (en) 1990-06-20
KR840004737A (ko) 1984-10-24
EP0096480A2 (en) 1983-12-21
IL68626A0 (en) 1983-09-30
IE831115L (en) 1983-11-24
CA1188702A (en) 1985-06-11
IL68626A (en) 1986-12-31
EP0096480B1 (en) 1988-09-28
EP0096480A3 (en) 1985-04-03
JPS58210079A (ja) 1983-12-07
DK210083D0 (da) 1983-05-11
GB2121038A (en) 1983-12-14
GR79272B (enExample) 1984-05-20
DE3378119D1 (en) 1988-11-03
DK210083A (da) 1983-11-25
US4395560A (en) 1983-07-26
HU193651B (en) 1987-11-30
GB8313470D0 (en) 1983-06-22

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee