IE48306B1 - Medicaments for treating hypertension - Google Patents

Medicaments for treating hypertension

Info

Publication number
IE48306B1
IE48306B1 IE2413/78A IE241378A IE48306B1 IE 48306 B1 IE48306 B1 IE 48306B1 IE 2413/78 A IE2413/78 A IE 2413/78A IE 241378 A IE241378 A IE 241378A IE 48306 B1 IE48306 B1 IE 48306B1
Authority
IE
Ireland
Prior art keywords
hydrogen
composition
compound
lower alkyl
formula
Prior art date
Application number
IE2413/78A
Other languages
English (en)
Other versions
IE782413L (en
Inventor
Zola P Horovitz
Bernard Rubin
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25343256&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IE48306(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of IE782413L publication Critical patent/IE782413L/xx
Publication of IE48306B1 publication Critical patent/IE48306B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IE2413/78A 1977-12-27 1978-12-06 Medicaments for treating hypertension IE48306B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US86442877A 1977-12-27 1977-12-27

Publications (2)

Publication Number Publication Date
IE782413L IE782413L (en) 1979-06-27
IE48306B1 true IE48306B1 (en) 1984-12-12

Family

ID=25343256

Family Applications (1)

Application Number Title Priority Date Filing Date
IE2413/78A IE48306B1 (en) 1977-12-27 1978-12-06 Medicaments for treating hypertension

Country Status (30)

Country Link
JP (1) JPS54110333A (de)
AR (1) AR230378A1 (de)
AU (1) AU526239B2 (de)
BE (1) BE873092A (de)
CA (1) CA1120400A (de)
CH (1) CH642542A5 (de)
DE (1) DE2854316C3 (de)
DK (1) DK578778A (de)
EG (1) EG14178A (de)
FI (1) FI783991A (de)
FR (1) FR2413089A1 (de)
GB (1) GB2010675B (de)
GR (1) GR72951B (de)
HK (1) HK45483A (de)
HU (1) HU178747B (de)
IE (1) IE48306B1 (de)
IL (1) IL56281A (de)
IT (1) IT1202811B (de)
KE (1) KE3235A (de)
LU (1) LU80709A1 (de)
MY (2) MY8300240A (de)
NL (2) NL192870C (de)
NO (1) NO784357L (de)
NZ (1) NZ189159A (de)
PH (1) PH22111A (de)
PL (1) PL212188A1 (de)
PT (1) PT68983A (de)
SE (1) SE445173B (de)
SG (1) SG41482G (de)
ZA (1) ZA786948B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5829950B2 (ja) * 1978-10-05 1983-06-25 ウェルファイド株式会社 環状イミノカルボン酸誘導体およびその塩類
US4350704A (en) 1980-10-06 1982-09-21 Warner-Lambert Company Substituted acyl derivatives of octahydro-1H-indole-2-carboxylic acids
US4482725A (en) * 1980-04-03 1984-11-13 E. R. Squibb & Sons, Inc. S-Acylation products of mercaptoacyl amino acids and carboxyl group containing diuretics
US4344949A (en) 1980-10-03 1982-08-17 Warner-Lambert Company Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids
US4532342A (en) * 1981-02-20 1985-07-30 Warner-Lambert Company N-substituted amino acids as intermediates in the preparation of acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids
US4552889A (en) * 1983-06-09 1985-11-12 Eli Lilly And Company 3-Mercaptomethyl-2-oxo-1-pyrrolidine acetic acids and use for hypertension
US4898729A (en) * 1983-12-09 1990-02-06 Euroceltique, S.A. Treatment of hypertension, compounds and compositions for antihypertension and diuresis
DE3532036A1 (de) * 1985-09-09 1987-03-26 Hoechst Ag Pharmazeutische zubereitung zur behandlung des bluthochdrucks
DK9200258U4 (da) * 1992-03-11 1993-07-23 Merck & Co Inc Farmaceutisk præparat indeholdende enalapril til brug mod hypertension
WO1996024358A1 (en) * 1995-02-10 1996-08-15 G.D. Searle & Co. Use of low dose amount of spironolactone for treatment of cardiovascular disease

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU509899B2 (en) * 1976-02-13 1980-05-29 E.R. Squibb & Sons, Inc. Proline derivatives and related compounds

Also Published As

Publication number Publication date
PL212188A1 (de) 1980-02-11
AR230378A1 (es) 1984-04-30
AU526239B2 (en) 1982-12-23
EG14178A (en) 1984-06-30
PH22111A (en) 1988-06-01
PT68983A (en) 1979-01-01
NZ189159A (en) 1984-12-14
CA1120400A (en) 1982-03-23
MY102991A (en) 1993-03-31
CH642542A5 (de) 1984-04-30
GB2010675B (en) 1982-06-16
IE782413L (en) 1979-06-27
NL192870B (nl) 1997-12-01
JPS647045B2 (de) 1989-02-07
FI783991A (fi) 1979-06-28
FR2413089B1 (de) 1980-12-26
DE2854316C2 (de) 1989-08-10
DE2854316C3 (de) 1994-12-22
HK45483A (en) 1983-10-28
GR72951B (de) 1984-01-17
IL56281A0 (en) 1979-03-12
NL980017I1 (nl) 1998-07-01
LU80709A1 (de) 1979-04-13
JPS54110333A (en) 1979-08-29
HU178747B (en) 1982-06-28
MY8300240A (en) 1983-12-31
GB2010675A (en) 1979-07-04
DK578778A (da) 1979-06-28
IT7831266A0 (it) 1978-12-22
FR2413089A1 (fr) 1979-07-27
SG41482G (en) 1985-01-11
DE2854316A1 (de) 1979-07-05
SE7813277L (sv) 1979-06-28
ZA786948B (en) 1980-04-30
BE873092A (fr) 1979-06-27
AU4204178A (en) 1979-07-05
IT1202811B (it) 1989-02-09
IL56281A (en) 1983-05-15
KE3235A (en) 1982-11-05
SE445173B (sv) 1986-06-09
NL192870C (nl) 1998-04-02
NL7812164A (nl) 1979-06-29
NO784357L (no) 1979-06-28

Similar Documents

Publication Publication Date Title
US4217347A (en) Method of treating hypertension and medicaments therefor
Murakami et al. Antihypertensive effect of 4 (-2'-nitrophenyl)-2, 6-dimethyl-1, 4-dihydropyridine-3, 5-dicarbonic acid dimethylester (nifedipine, bay-a 1040), a new coronary dilator
EP1154777B1 (de) Arzneimittel zur behandlung von bluthochdruck
JPS58134031A (ja) 多発性硬化症処置におけるジヒドロシクロスポリンｄ
IE48306B1 (en) Medicaments for treating hypertension
EP0629400B1 (de) Idebenone-haltige Zusammensetzungen zur Behandlung von M. Alzheimer
Walker et al. Comparative antihypertensive effects of guanabenz and clonidine
US4794112A (en) Acetaminophen/hydroxyzine analgesic combinations
DK165966B (da) Forbedret piroxicamholdigt anti-inflammatorisk praeparat
Faerchtein et al. A placebo controlled trial of the alpha-blocker, indoramin, in the treatment of arterial hypertension
NL8105635A (nl) Geneesmiddel met transplantaatafstotings- en/of immunologische ontstekingsremmende werking, alsmede werkwijze voor de remming van transplantaatafstoting en/of immunologische ontsteking.
US3988461A (en) Pharmaceutical composition for the treatment of Parkinson's disease
GB1584089A (en) Antihypertensive pharmaceutical compositions
JP3024789B2 (ja) 血圧降下剤
KR100260479B1 (ko) 혈압강하용 복합제제
NL194958C (nl) Farmaceutische eenheidsdosering van benazepril/thiazidediureticum in lage dosering.
KR0132568B1 (ko) 이뇨 또는 항고혈압 조성물
JPH04279524A (ja) 脳血管疾患治療剤
IE43955B1 (en) Pharmaceutical composition and dosage units thereof
US3904758A (en) Method of increasing wakefulness
JPH0138086B2 (de)
US3780180A (en) N-substituted amino-n-nitroso-aminoace-tonitriles in the treatment of hypertension
EP0172917A1 (de) Agenzien zur behandlung von immunodefizienz, deren behandlungsverfahren sowie deren verwendung
Schoenberger Calcium antagonists: use in hypertension evaluation of calcium antagonists in combination with diuretics.
HU206612B (en) Process for producing antihypertenzive combinative composition