IE47458B1 - Quinolylguanidine derivatives - Google Patents

Quinolylguanidine derivatives

Info

Publication number
IE47458B1
IE47458B1 IE2084/78A IE208478A IE47458B1 IE 47458 B1 IE47458 B1 IE 47458B1 IE 2084/78 A IE2084/78 A IE 2084/78A IE 208478 A IE208478 A IE 208478A IE 47458 B1 IE47458 B1 IE 47458B1
Authority
IE
Ireland
Prior art keywords
compound
formula
complexes
pharmaceutically acceptable
acid
Prior art date
Application number
IE2084/78A
Other languages
English (en)
Other versions
IE782084L (en
Original Assignee
Leo Pharm Prod Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leo Pharm Prod Ltd filed Critical Leo Pharm Prod Ltd
Publication of IE782084L publication Critical patent/IE782084L/xx
Publication of IE47458B1 publication Critical patent/IE47458B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
IE2084/78A 1977-11-07 1978-10-20 Quinolylguanidine derivatives IE47458B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB4616677 1977-11-07

Publications (2)

Publication Number Publication Date
IE782084L IE782084L (en) 1979-05-07
IE47458B1 true IE47458B1 (en) 1984-03-21

Family

ID=10440127

Family Applications (1)

Application Number Title Priority Date Filing Date
IE2084/78A IE47458B1 (en) 1977-11-07 1978-10-20 Quinolylguanidine derivatives

Country Status (24)

Country Link
US (1) US4293549A (en, 2012)
JP (1) JPS5473784A (en, 2012)
AT (1) AT366368B (en, 2012)
AU (1) AU517670B2 (en, 2012)
BE (1) BE871807A (en, 2012)
CA (1) CA1120929A (en, 2012)
CH (1) CH645354A5 (en, 2012)
DE (1) DE2847792A1 (en, 2012)
DK (1) DK153950C (en, 2012)
ES (1) ES474900A1 (en, 2012)
FI (1) FI69463C (en, 2012)
FR (1) FR2407930A1 (en, 2012)
GR (1) GR65010B (en, 2012)
IE (1) IE47458B1 (en, 2012)
IT (1) IT1100075B (en, 2012)
LU (1) LU80476A1 (en, 2012)
NL (1) NL7811035A (en, 2012)
NZ (1) NZ188770A (en, 2012)
PH (1) PH16296A (en, 2012)
PT (1) PT68750A (en, 2012)
SE (1) SE446267B (en, 2012)
SU (1) SU828967A3 (en, 2012)
YU (1) YU41129B (en, 2012)
ZA (1) ZA786175B (en, 2012)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6306846B1 (en) * 1972-05-31 2001-10-23 John R. J. Sorenson Anti-inflammatory and anti-ulcer compounds and process
IT1205640B (it) * 1983-04-06 1989-03-23 Yason Srl Nuovi composti ad attivita' antiinfiammatoria,procedimento per la loro preparazione e composizioni farmaceutiche che li contengono
US4563460A (en) * 1984-01-13 1986-01-07 William H. Rorer, Inc. Quinoline and quinazoline derivatives for treating gastrointestinal motility dysfunctions
HU195487B (en) * 1985-06-04 1988-05-30 Egyt Gyogyszervegyeszeti Gyar Process for producing quinoline derivatives
ES2031514T3 (es) * 1986-08-29 1992-12-16 Pfizer Inc. 2-guanidino-4-ariltiazoles para el tratamiento de ulceras pepticas.
US6100260A (en) * 1997-04-21 2000-08-08 Sumitomo Pharmaceutical Company, Limited Isoxazole derivatives
EP0928793B1 (en) * 1998-01-02 2002-05-15 F. Hoffmann-La Roche Ag Thiazole derivatives
RU2202344C2 (ru) 1998-03-26 2003-04-20 Джапан Тобакко Инк. Антагонисты ноцицептина, производные амида, аналгетик, способ инициирования антагонистического действия к ноцицептину, способ лечения боли, фармацевтические композиции
EP1237849A1 (en) * 1999-11-05 2002-09-11 University College London Activators of soluble guanylate cyclase
AU2003303678A1 (en) * 2003-01-03 2004-08-10 Genzyme Corporation Urea derivatives and their use as anti-inflammatory agents
ES2387909T3 (es) * 2003-01-14 2012-10-03 Cytokinetics, Inc. Compuestos, composiciones y procedimientos de tratamiento de la insuficiencia cardiaca
GB0404434D0 (en) 2004-02-27 2004-03-31 Novartis Ag Organic compounds
US9296697B2 (en) * 2005-08-24 2016-03-29 Abbott Laboratories Hetaryl-substituted guanidine compounds and use thereof as binding partners for 5-HT5-receptors
WO2023003497A1 (ru) * 2021-07-23 2023-01-26 Общество С Ограниченной Ответственностью "Валента-Интеллект" Соединения с лизосомотропной и противовирусной активностью

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB889282A (en) * 1957-05-07 1962-02-14 Air Reduction Preparation of hexafluorodiethyl ether and medicinal compositions containing it
GB889262A (en) * 1959-07-03 1962-02-14 Ciba Ltd Quinoline compounds
US3159676A (en) * 1962-02-07 1964-12-01 Smith Kline French Lab Naphthyl containing guanidines
US3852293A (en) 1972-06-21 1974-12-03 Uniroyal Inc 4-phenyl-2-(3-pyridyl)-thiazole carboxamides
US4000279A (en) * 1974-10-29 1976-12-28 Armour Pharmaceutical Company Pharmaceutical preparations containing 5'-(8'-hydroxyquinolyl)guanidine compounds and methods of using same

Also Published As

Publication number Publication date
PH16296A (en) 1983-09-05
JPS6348873B2 (en, 2012) 1988-09-30
ZA786175B (en) 1979-10-31
DK153950C (da) 1989-02-20
DK153950B (da) 1988-09-26
PT68750A (en) 1978-12-01
SE7811457L (sv) 1979-05-08
US4293549A (en) 1981-10-06
NZ188770A (en) 1984-07-31
DK493378A (da) 1979-05-08
GR65010B (en) 1980-06-12
ATA773278A (de) 1981-08-15
IT1100075B (it) 1985-09-28
FI69463C (fi) 1986-02-10
LU80476A1 (fr) 1979-06-15
ES474900A1 (es) 1980-04-16
DE2847792C2 (en, 2012) 1988-02-04
FR2407930A1 (fr) 1979-06-01
AT366368B (de) 1982-04-13
FI783327A7 (fi) 1979-05-08
IE782084L (en) 1979-05-07
DE2847792A1 (de) 1979-05-10
AU4137678A (en) 1979-05-17
SU828967A3 (ru) 1981-05-07
NL7811035A (nl) 1979-05-09
IT7829514A0 (it) 1978-11-07
FR2407930B1 (en, 2012) 1983-03-18
YU257578A (en) 1983-01-21
CA1120929A (en) 1982-03-30
YU41129B (en) 1986-12-31
JPS5473784A (en) 1979-06-13
CH645354A5 (de) 1984-09-28
BE871807A (fr) 1979-05-07
SE446267B (sv) 1986-08-25
FI69463B (fi) 1985-10-31
AU517670B2 (en) 1981-08-20

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Legal Events

Date Code Title Description
MM4A Patent lapsed