IE43778B1 - Solid solutions of ergot alkaloids in polymers - Google Patents

Solid solutions of ergot alkaloids in polymers

Info

Publication number
IE43778B1
IE43778B1 IE2282/76A IE228276A IE43778B1 IE 43778 B1 IE43778 B1 IE 43778B1 IE 2282/76 A IE2282/76 A IE 2282/76A IE 228276 A IE228276 A IE 228276A IE 43778 B1 IE43778 B1 IE 43778B1
Authority
IE
Ireland
Prior art keywords
composition
polymer
molecular weight
solid
weight
Prior art date
Application number
IE2282/76A
Other languages
English (en)
Other versions
IE43778L (en
Original Assignee
Sandoz Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ltd filed Critical Sandoz Ltd
Publication of IE43778L publication Critical patent/IE43778L/xx
Publication of IE43778B1 publication Critical patent/IE43778B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/48—Ergoline derivatives, e.g. lysergic acid, ergotamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IE2282/76A 1975-10-17 1976-10-15 Solid solutions of ergot alkaloids in polymers IE43778B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2546577A DE2546577B2 (de) 1975-10-17 1975-10-17 Feste Stoffe aus Polyvinylpyrrolidon und Ergotalkaloiden

Publications (2)

Publication Number Publication Date
IE43778L IE43778L (en) 1977-04-17
IE43778B1 true IE43778B1 (en) 1981-05-20

Family

ID=5959411

Family Applications (1)

Application Number Title Priority Date Filing Date
IE2282/76A IE43778B1 (en) 1975-10-17 1976-10-15 Solid solutions of ergot alkaloids in polymers

Country Status (28)

Country Link
JP (1) JPS5854122B2 (cs)
AT (1) AT362510B (cs)
AU (1) AU508628B2 (cs)
BE (1) BE847368A (cs)
CA (1) CA1079641A (cs)
CH (1) CH643737A5 (cs)
CS (1) CS199647B2 (cs)
DE (1) DE2546577B2 (cs)
DK (1) DK146194C (cs)
ES (1) ES452420A1 (cs)
FI (1) FI762875A7 (cs)
FR (1) FR2327764A1 (cs)
GB (1) GB1560406A (cs)
GR (1) GR61268B (cs)
HK (1) HK3183A (cs)
HU (1) HU172533B (cs)
IE (1) IE43778B1 (cs)
IL (1) IL50686A (cs)
MY (1) MY8400063A (cs)
NL (1) NL184558C (cs)
NO (1) NO144468C (cs)
NZ (1) NZ182341A (cs)
PH (1) PH14513A (cs)
PT (1) PT65719B (cs)
SE (1) SE430379B (cs)
SG (1) SG63082G (cs)
SU (1) SU1165223A3 (cs)
ZA (1) ZA766166B (cs)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1572226A (en) * 1977-11-03 1980-07-30 Hoechst Uk Ltd Pharmaceutical preparations in solid unit dosage form
WO1980001242A1 (fr) * 1978-12-21 1980-06-26 Sandoz Ag Preparations galeniques
US4411882A (en) 1978-12-21 1983-10-25 Sandoz Ltd. Galenical compositions
FR2454804B1 (fr) * 1979-04-26 1986-11-21 Sanofi Sa Medicament a base de dihydroergotoxine et son procede de preparation
US4366145A (en) * 1981-06-24 1982-12-28 Sandoz, Inc. Soft gelatin capsule with a liquid ergot alkaloid center fill solution and method of preparation
US4898729A (en) * 1983-12-09 1990-02-06 Euroceltique, S.A. Treatment of hypertension, compounds and compositions for antihypertension and diuresis
NL194389C (nl) * 1984-06-14 2002-03-04 Novartis Ag Werkwijze voor het bereiden van een vaste dispersie van een farmaceutisch actief middel dat een lage oplosbaarheid in water heeft, in een vaste matrix van een in water oplosbaar polyalkyleenglycol als drager.
EP0277092B1 (de) * 1987-01-14 1992-01-29 Ciba-Geigy Ag Therapeutisches System für schwerlösliche Wirkstoffe
FR2610827B1 (fr) * 1987-02-18 1991-09-13 Pf Medicament Comprime de dihydroergotamine (d.h.e.) du type a matrice hydrophile et son procede de fabrication
US5064656A (en) * 1989-11-14 1991-11-12 Dr. Gergely & Co. Uncoated pharmaceutical reaction tablet
DE4401646A1 (de) * 1994-01-21 1995-07-27 Krewel Werke Gmbh Optimal freisetzende Kava-Extrakte
US6524832B1 (en) 1994-02-04 2003-02-25 Arch Development Corporation DNA damaging agents in combination with tyrosine kinase inhibitors
PL192423B1 (pl) * 1997-12-22 2006-10-31 Schering Corp Kompozycja farmaceutyczna typu molekularnej dyspersji
US6632455B2 (en) 1997-12-22 2003-10-14 Schering Corporation Molecular dispersion composition with enhanced bioavailability
US6316462B1 (en) 1999-04-09 2001-11-13 Schering Corporation Methods of inducing cancer cell death and tumor regression
EP1235574B1 (en) * 1999-12-03 2005-02-02 Polichem S.A. Methods for making sustained-release pharmaceutical compositions of ergot alkaloids having improved bioavailability and compositions thereof
US7771746B2 (en) 1999-12-03 2010-08-10 Polichem Sa Methods for making sustained-release pharmaceutical compositions of ergot alkaloids having improved bioavailability and compositions thereof
US7135436B2 (en) 2003-05-05 2006-11-14 J.F. Daley International, Ltd. Solid algicide, preparation and usage in recirculating water
WO2005000273A1 (en) * 2003-06-27 2005-01-06 Bioprogress S.P.A. Composite product obtainable by cogrinding of a active principle with a copolymer n-vinyl-2-pyrrolidone/vinyl-acetate
US12133911B2 (en) 2015-06-09 2024-11-05 Capsugel Belgium Nv Formulations to achieve rapid dissolution of drug from spray-dried dispersions in capsules

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1175430A (en) * 1966-04-07 1969-12-23 Sandoz Ltd Pharmaceutical Compositions containing Ergot Alkaloids

Also Published As

Publication number Publication date
FI762875A7 (cs) 1977-04-18
DK146194B (da) 1983-07-25
NZ182341A (en) 1978-09-20
HU172533B (hu) 1978-09-28
ZA766166B (en) 1978-05-30
AU508628B2 (en) 1980-03-27
MY8400063A (en) 1984-12-31
JPS5854122B2 (ja) 1983-12-02
SE430379B (sv) 1983-11-14
SG63082G (en) 1983-09-09
DE2546577B2 (de) 1981-04-02
DE2546577A1 (de) 1977-04-21
PH14513A (en) 1981-08-24
FR2327764B1 (cs) 1979-03-02
FR2327764A1 (fr) 1977-05-13
DK454176A (da) 1977-04-18
PT65719B (fr) 1978-06-12
CA1079641A (en) 1980-06-17
BE847368A (fr) 1977-04-15
IE43778L (en) 1977-04-17
AT362510B (de) 1981-05-25
IL50686A0 (en) 1976-12-31
SU1165223A3 (ru) 1985-06-30
ATA767976A (de) 1980-10-15
GR61268B (en) 1978-10-17
NO144468C (no) 1981-09-09
NO763446L (cs) 1977-04-19
ES452420A1 (es) 1978-04-16
NO144468B (no) 1981-06-01
CH643737A5 (en) 1984-06-29
JPS5251014A (en) 1977-04-23
NL184558B (nl) 1989-04-03
SE7611189L (sv) 1977-04-18
DK146194C (da) 1984-01-02
HK3183A (en) 1983-01-20
PT65719A (fr) 1976-11-01
NL7611295A (nl) 1977-04-19
NL184558C (nl) 1989-09-01
AU1875476A (en) 1978-04-20
CS199647B2 (en) 1980-07-31
GB1560406A (en) 1980-02-06
IL50686A (en) 1979-05-31

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MM4A Patent lapsed