IE39278B1 - Fluoro substituted phenothiazines method for preparation thereof and composaitions - Google Patents

Fluoro substituted phenothiazines method for preparation thereof and composaitions

Info

Publication number
IE39278B1
IE39278B1 IE1084/74A IE108474A IE39278B1 IE 39278 B1 IE39278 B1 IE 39278B1 IE 1084/74 A IE1084/74 A IE 1084/74A IE 108474 A IE108474 A IE 108474A IE 39278 B1 IE39278 B1 IE 39278B1
Authority
IE
Ireland
Prior art keywords
formula
compound
reaction
prepared
fluoro
Prior art date
Application number
IE1084/74A
Other languages
English (en)
Other versions
IE39278L (en
Original Assignee
Kefalas As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kefalas As filed Critical Kefalas As
Publication of IE39278L publication Critical patent/IE39278L/xx
Publication of IE39278B1 publication Critical patent/IE39278B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
IE1084/74A 1973-06-08 1974-05-21 Fluoro substituted phenothiazines method for preparation thereof and composaitions IE39278B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2752773A GB1460713A (en) 1973-06-08 1973-06-08 7-fluoro substituted phenothiazines method for preparation thereof and compositions bladed rotor for a gas turbine engine

Publications (2)

Publication Number Publication Date
IE39278L IE39278L (en) 1974-12-08
IE39278B1 true IE39278B1 (en) 1978-09-13

Family

ID=10261046

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1084/74A IE39278B1 (en) 1973-06-08 1974-05-21 Fluoro substituted phenothiazines method for preparation thereof and composaitions

Country Status (17)

Country Link
US (1) US3966930A (OSRAM)
JP (1) JPS5025574A (OSRAM)
AT (1) AT333296B (OSRAM)
BE (1) BE816128A (OSRAM)
CA (1) CA1027563A (OSRAM)
CH (1) CH610317A5 (OSRAM)
DE (1) DE2426149C3 (OSRAM)
DK (1) DK308174A (OSRAM)
ES (1) ES427079A1 (OSRAM)
FI (1) FI55335C (OSRAM)
FR (1) FR2232324B1 (OSRAM)
GB (1) GB1460713A (OSRAM)
IE (1) IE39278B1 (OSRAM)
NL (1) NL7407643A (OSRAM)
NO (1) NO141649C (OSRAM)
SE (1) SE407939B (OSRAM)
ZA (1) ZA743407B (OSRAM)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1540842A (en) * 1976-08-25 1979-02-14 Kefalas As Phenothiazines
JPS55111483A (en) * 1979-02-22 1980-08-28 Eisai Co Ltd Novel phenothiazine derivative and psychotropic drug comprising it
FR2691459B1 (fr) * 1992-05-25 1995-06-09 Adir Nouveaux derives de la phenothiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
RU2179169C2 (ru) * 2000-02-11 2002-02-10 Государственный научный центр РФ "НИОПИК" Способ получения дигидрохлорида 2-трифторметил-10-[3-(1-метил-пиперазинил-4)-пропил]-фенотиазина
AU2004201240B2 (en) * 2001-09-27 2008-08-07 Bar Ilan University Conjugated Psychotropic Drugs and Uses Thereof
JP4521187B2 (ja) 2001-09-27 2010-08-11 ラモト アット テル アヴィヴ ユニヴァーシティ リミテッド コンジュゲートされた抗精神病薬およびこれらの使用
US7544681B2 (en) 2001-09-27 2009-06-09 Ramot At Tel Aviv University Ltd. Conjugated psychotropic drugs and uses thereof
JP5284779B2 (ja) * 2005-06-07 2013-09-11 ラモット・アット・テル・アビブ・ユニバーシテイ・リミテッド コンジュゲート化された向精神薬の新規な塩およびその調製方法
WO2008010222A2 (en) 2006-07-17 2008-01-24 Ramot At Tel Aviv University Ltd. Conjugates comprising a gaba- or glycine compound, pharmaceutical compositions and combinations thereof and their use in treating cns disorders
EP2252578B1 (en) 2008-02-11 2012-08-01 Ramot at Tel Aviv University Ltd. Conjugates for treating neurodegenerative diseases and disorders
WO2011070579A1 (en) 2009-12-09 2011-06-16 Biolinerx Ltd. Methods of improving cognitive functions
US8377929B2 (en) 2010-02-24 2013-02-19 Ramot At Tel-Aviv University Ltd. Crystalline forms of the tri-mesylate salt of perphenazine-GABA and process of producing the same
US8916610B2 (en) 2010-09-22 2014-12-23 Ramot At Tel-Aviv University Ltd. Acid addition salt of a nortriptyline-GABA conjugate and a process of preparing same

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3004028A (en) * 1961-10-10 Preparation of phenothiazines
NL108827C (OSRAM) * 1956-04-09
NL105973C (OSRAM) * 1957-09-11 1900-01-01
FR1212031A (fr) * 1957-10-21 1960-03-21 Rhone Poulenc Sa Dérivés de la phénothiazine substitués à l'azote par une chaîne basique comportant un hétérocycle et leur préparation
US2945030A (en) * 1958-07-24 1960-07-12 Smith Kline French Lab Substituted aralkyl phenothiazinylalkyl piperazines
NL108955C (OSRAM) * 1959-05-08
US3169962A (en) * 1963-02-28 1965-02-16 Olin Mathieson Benzhydryl ethers of 10-(hydroxyethylpiperazinopropyl) phenothiazines
US3419553A (en) * 1966-05-25 1968-12-31 Squibb & Sons Inc Fluorinated phenothiazine compounds
BE787967A (fr) * 1971-08-25 1973-02-26 May & Baker Ltd Derives de la phenothiazine antispastiques

Also Published As

Publication number Publication date
US3966930A (en) 1976-06-29
FR2232324B1 (OSRAM) 1977-11-04
NO141649B (no) 1980-01-07
FR2232324A1 (OSRAM) 1975-01-03
FI55335B (fi) 1979-03-30
ATA457374A (de) 1976-03-15
DE2426149C3 (de) 1980-10-09
BE816128A (fr) 1974-12-10
FI173574A7 (OSRAM) 1974-12-09
NO742075L (OSRAM) 1975-01-06
ZA743407B (en) 1975-06-25
GB1460713A (en) 1977-01-06
CH610317A5 (OSRAM) 1979-04-12
AT333296B (de) 1976-11-10
NO141649C (no) 1980-04-16
AU6931574A (en) 1975-11-27
JPS5025574A (OSRAM) 1975-03-18
CA1027563A (en) 1978-03-07
DK308174A (OSRAM) 1975-02-03
FI55335C (fi) 1979-07-10
DE2426149A1 (de) 1975-01-02
NL7407643A (OSRAM) 1974-12-10
ES427079A1 (es) 1976-07-16
SE7407518L (OSRAM) 1974-12-09
DE2426149B2 (de) 1980-01-31
IE39278L (en) 1974-12-08
SE407939B (sv) 1979-04-30

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