IE38713L - Antimicrobial preparations - Google Patents

Antimicrobial preparations

Info

Publication number
IE38713L
IE38713L IE740010A IE1074A IE38713L IE 38713 L IE38713 L IE 38713L IE 740010 A IE740010 A IE 740010A IE 1074 A IE1074 A IE 1074A IE 38713 L IE38713 L IE 38713L
Authority
IE
Ireland
Prior art keywords
sulphonamides
compounds
carbon atoms
aqueous solutions
water
Prior art date
Application number
IE740010A
Other versions
IE38713B1 (en
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of IE38713L publication Critical patent/IE38713L/en
Publication of IE38713B1 publication Critical patent/IE38713B1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/63Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/63Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Compounds of the formula 10 in which R<7>, R<8> and R<9>, which can be identical or different, are each an alkyl or alkoxy group with 1 to 4 carbon atoms, or R<7> and R<8> together are an alkylenedioxy group with 1 to 4 carbon atoms, are prepared by reacting correspondingly substituted benzylacrylo- or benzylpropionitrile with guanidine. The compounds are intended in the form of their pharmaceutically acceptable monoacid addition salts as potentiator for sulphonamides in the preparation of clear aqueous solutions of sulphonamides in a medicinally acceptable, water-miscible organic solvent and water. The clear aqueous solutions are suitable for injection and infusion purposes and are distinguished by being well tolerated and having high stability. They can, for example, be injected directly into the veins without causing clot formation or tissue damage. <IMAGE> [GB1469521A]
IE10/74A 1973-01-05 1974-01-03 Antimicrobial preparations IE38713B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB69073A GB1469521A (en) 1973-01-05 1973-01-05 Antimicrobial preparations

Publications (2)

Publication Number Publication Date
IE38713L true IE38713L (en) 1975-07-03
IE38713B1 IE38713B1 (en) 1978-05-24

Family

ID=9708818

Family Applications (1)

Application Number Title Priority Date Filing Date
IE10/74A IE38713B1 (en) 1973-01-05 1974-01-03 Antimicrobial preparations

Country Status (31)

Country Link
JP (1) JPS5344531B2 (en)
AR (1) AR204521A1 (en)
AT (1) AT331986B (en)
AU (1) AU472758B2 (en)
BE (1) BE809378A (en)
CA (1) CA1014067A (en)
CH (4) CH616930A5 (en)
CS (1) CS212740B2 (en)
CY (1) CY1070A (en)
DD (2) DD115120A5 (en)
DE (1) DE2400218A1 (en)
DK (1) DK138006B (en)
ES (1) ES427078A1 (en)
FI (1) FI55296C (en)
FR (1) FR2213060B1 (en)
GB (1) GB1469521A (en)
HK (1) HK44280A (en)
HU (1) HU171200B (en)
IE (1) IE38713B1 (en)
IL (1) IL43954A (en)
IN (1) IN138511B (en)
IT (1) IT8047967A0 (en)
KE (1) KE3065A (en)
MW (1) MW174A1 (en)
MY (1) MY8100146A (en)
NL (1) NL183927C (en)
NO (1) NO140578C (en)
PH (1) PH12388A (en)
SE (1) SE430847B (en)
ZA (1) ZA7461B (en)
ZM (1) ZM20173A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1596044A (en) * 1977-04-14 1981-08-19 Wellcome Found Veterinary compositions
DE2731013C2 (en) * 1977-07-08 1982-07-15 Lentia Gmbh Process for the preparation of an aqueous solution for infusion
DE2963408D1 (en) 1978-08-01 1982-09-16 Ciba Geigy Ag Stable medicinal solution on the basis of 2,6-diamino-5-(3',4',5'-trimethoxybenzyl)-pyrimidine(trimethoprim) and a sulphonamide, process for preparing and using it
HU180740B (en) * 1979-11-27 1983-04-29 Egyt Gyogyszervegyeszeti Gyar Process for producing sulfonamide-containing,injectable pharmaceutical composition of prolongated activity
CH647412A5 (en) * 1980-03-25 1985-01-31 Hoffmann La Roche PHARMACEUTICAL PREPARATIONS.
HU212498B (en) * 1992-11-06 1996-07-29 Egyt Gyogyszervegyeszeti Gyar Process for producing water-soluble pharmaceutical compositions, containing sulfachlorpyridazin-sodium and trimethoprim
DE4331147A1 (en) 1993-09-14 1995-03-16 Nycomed Arzneimittel Gmbh Aqueous solution which can be administered intravenously
WO2018229659A1 (en) 2017-06-13 2018-12-20 3M Innovative Properties Company Modified polytetrafluoroethylene and aqueous dispersion containing the same
EP3527634A1 (en) 2018-02-15 2019-08-21 3M Innovative Properties Company Fluoropolymers and fluoropolymer dispersions

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1028204A (en) * 1963-06-28 1966-05-04 May & Baker Ltd Veterinary coccidiostatic compositions
BR6915082D0 (en) * 1969-05-16 1973-03-08 Wellcome Found PROCESS OF PREPARATION OF BENZYL-PYRIMIDINES
RO67383A (en) * 1970-10-22 1981-07-30 The Wellcome Foundation Ltd,Gb PROCESS FOR THE PREPARATION OF 2,4-DIAMINO-5-BENZYLPIRIMIDINE
GB1407971A (en) * 1971-04-16 1975-10-01 Wellcome Found 2,4-diamino -4-3,4,5-triethoxybenzyl pyrimidine and methods of preparation therefor
BE787236A (en) * 1971-08-05 1973-02-05 Wellcome Found POTENTIALIZATION COMPOSITIONS

Also Published As

Publication number Publication date
AU472758B2 (en) 1976-06-03
CS212740B2 (en) 1982-03-26
DK138006C (en) 1979-01-08
FR2213060B1 (en) 1976-09-03
HK44280A (en) 1980-08-22
FI55296B (en) 1979-03-30
ATA2274A (en) 1975-12-15
AU6413674A (en) 1975-07-03
CH616931A5 (en) 1980-04-30
IE38713B1 (en) 1978-05-24
ZM20173A1 (en) 1974-09-23
SE430847B (en) 1983-12-19
AR204521A1 (en) 1976-02-12
NL7400094A (en) 1974-07-09
IL43954A0 (en) 1974-05-16
ZA7461B (en) 1975-08-27
BE809378A (en) 1974-07-03
NL183927C (en) 1989-03-01
JPS49100215A (en) 1974-09-21
CY1070A (en) 1980-10-24
CA1014067A (en) 1977-07-19
FR2213060A1 (en) 1974-08-02
HU171200B (en) 1977-11-28
IL43954A (en) 1977-05-31
NO140578C (en) 1979-10-03
DD115120A5 (en) 1975-09-12
CH628335A5 (en) 1982-02-26
DK138006B (en) 1978-06-26
MW174A1 (en) 1975-08-13
NO740022L (en) 1974-07-08
DD111156A5 (en) 1975-02-05
CH616930A5 (en) 1980-04-30
KE3065A (en) 1980-07-25
ES427078A1 (en) 1976-07-16
GB1469521A (en) 1977-04-06
CH616932A5 (en) 1980-04-30
PH12388A (en) 1979-01-29
IN138511B (en) 1976-02-14
AT331986B (en) 1976-09-10
DE2400218A1 (en) 1974-07-18
FI55296C (en) 1979-07-10
JPS5344531B2 (en) 1978-11-29
MY8100146A (en) 1981-12-31
NL183927B (en) 1988-10-03
IT8047967A0 (en) 1980-02-21
NO140578B (en) 1979-06-25

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