ES427078A1 - Antimicrobial preparations - Google Patents
Antimicrobial preparationsInfo
- Publication number
- ES427078A1 ES427078A1 ES427078A ES427078A ES427078A1 ES 427078 A1 ES427078 A1 ES 427078A1 ES 427078 A ES427078 A ES 427078A ES 427078 A ES427078 A ES 427078A ES 427078 A1 ES427078 A1 ES 427078A1
- Authority
- ES
- Spain
- Prior art keywords
- sulphonamides
- compounds
- carbon atoms
- aqueous solutions
- water
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
- A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
Compounds of the formula 10 in which R<7>, R<8> and R<9>, which can be identical or different, are each an alkyl or alkoxy group with 1 to 4 carbon atoms, or R<7> and R<8> together are an alkylenedioxy group with 1 to 4 carbon atoms, are prepared by reacting correspondingly substituted benzylacrylo- or benzylpropionitrile with guanidine. The compounds are intended in the form of their pharmaceutically acceptable monoacid addition salts as potentiator for sulphonamides in the preparation of clear aqueous solutions of sulphonamides in a medicinally acceptable, water-miscible organic solvent and water. The clear aqueous solutions are suitable for injection and infusion purposes and are distinguished by being well tolerated and having high stability. They can, for example, be injected directly into the veins without causing clot formation or tissue damage.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB69073A GB1469521A (en) | 1973-01-05 | 1973-01-05 | Antimicrobial preparations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES427078A1 true ES427078A1 (en) | 1976-07-16 |
Family
ID=9708818
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES427078A Expired ES427078A1 (en) | 1973-01-05 | 1974-06-07 | Antimicrobial preparations |
Country Status (31)
| Country | Link |
|---|---|
| JP (1) | JPS5344531B2 (en) |
| AR (1) | AR204521A1 (en) |
| AT (1) | AT331986B (en) |
| AU (1) | AU472758B2 (en) |
| BE (1) | BE809378A (en) |
| CA (1) | CA1014067A (en) |
| CH (4) | CH616930A5 (en) |
| CS (1) | CS212740B2 (en) |
| CY (1) | CY1070A (en) |
| DD (2) | DD115120A5 (en) |
| DE (1) | DE2400218A1 (en) |
| DK (1) | DK138006B (en) |
| ES (1) | ES427078A1 (en) |
| FI (1) | FI55296C (en) |
| FR (1) | FR2213060B1 (en) |
| GB (1) | GB1469521A (en) |
| HK (1) | HK44280A (en) |
| HU (1) | HU171200B (en) |
| IE (1) | IE38713B1 (en) |
| IL (1) | IL43954A (en) |
| IN (1) | IN138511B (en) |
| IT (1) | IT8047967A0 (en) |
| KE (1) | KE3065A (en) |
| MW (1) | MW174A1 (en) |
| MY (1) | MY8100146A (en) |
| NL (1) | NL183927C (en) |
| NO (1) | NO140578C (en) |
| PH (1) | PH12388A (en) |
| SE (1) | SE430847B (en) |
| ZA (1) | ZA7461B (en) |
| ZM (1) | ZM20173A1 (en) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1596044A (en) * | 1977-04-14 | 1981-08-19 | Wellcome Found | Veterinary compositions |
| DE2731013C2 (en) * | 1977-07-08 | 1982-07-15 | Lentia Gmbh | Process for the preparation of an aqueous solution for infusion |
| DE2963408D1 (en) | 1978-08-01 | 1982-09-16 | Ciba Geigy Ag | Stable medicinal solution on the basis of 2,6-diamino-5-(3',4',5'-trimethoxybenzyl)-pyrimidine(trimethoprim) and a sulphonamide, process for preparing and using it |
| HU180740B (en) * | 1979-11-27 | 1983-04-29 | Egyt Gyogyszervegyeszeti Gyar | Process for producing sulfonamide-containing,injectable pharmaceutical composition of prolongated activity |
| CH647412A5 (en) * | 1980-03-25 | 1985-01-31 | Hoffmann La Roche | PHARMACEUTICAL PREPARATIONS. |
| HU212498B (en) * | 1992-11-06 | 1996-07-29 | Egyt Gyogyszervegyeszeti Gyar | Process for producing water-soluble pharmaceutical compositions, containing sulfachlorpyridazin-sodium and trimethoprim |
| DE4331147A1 (en) | 1993-09-14 | 1995-03-16 | Nycomed Arzneimittel Gmbh | Aqueous solution which can be administered intravenously |
| WO2018229659A1 (en) | 2017-06-13 | 2018-12-20 | 3M Innovative Properties Company | Modified polytetrafluoroethylene and aqueous dispersion containing the same |
| EP3527634A1 (en) | 2018-02-15 | 2019-08-21 | 3M Innovative Properties Company | Fluoropolymers and fluoropolymer dispersions |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1028204A (en) * | 1963-06-28 | 1966-05-04 | May & Baker Ltd | Veterinary coccidiostatic compositions |
| BR6915082D0 (en) * | 1969-05-16 | 1973-03-08 | Wellcome Found | PROCESS OF PREPARATION OF BENZYL-PYRIMIDINES |
| RO67383A (en) * | 1970-10-22 | 1981-07-30 | The Wellcome Foundation Ltd,Gb | PROCESS FOR THE PREPARATION OF 2,4-DIAMINO-5-BENZYLPIRIMIDINE |
| GB1407971A (en) * | 1971-04-16 | 1975-10-01 | Wellcome Found | 2,4-diamino -4-3,4,5-triethoxybenzyl pyrimidine and methods of preparation therefor |
| BE787236A (en) * | 1971-08-05 | 1973-02-05 | Wellcome Found | POTENTIALIZATION COMPOSITIONS |
-
1973
- 1973-01-05 GB GB69073A patent/GB1469521A/en not_active Expired
- 1973-12-27 ZM ZM201/73A patent/ZM20173A1/en unknown
-
1974
- 1974-01-01 AR AR251788A patent/AR204521A1/en active
- 1974-01-02 HU HU74WE00000498A patent/HU171200B/en unknown
- 1974-01-02 FI FI8/74A patent/FI55296C/en active
- 1974-01-02 AT AT2274*#A patent/AT331986B/en not_active IP Right Cessation
- 1974-01-03 BE BE139505A patent/BE809378A/en not_active IP Right Cessation
- 1974-01-03 AU AU64136/74A patent/AU472758B2/en not_active Expired
- 1974-01-03 DD DD182544A patent/DD115120A5/xx unknown
- 1974-01-03 FR FR7400111A patent/FR2213060B1/fr not_active Expired
- 1974-01-03 DK DK4074AA patent/DK138006B/en not_active IP Right Cessation
- 1974-01-03 CS CS7435A patent/CS212740B2/en unknown
- 1974-01-03 IN IN19/CAL/1974A patent/IN138511B/en unknown
- 1974-01-03 DE DE2400218A patent/DE2400218A1/en not_active Withdrawn
- 1974-01-03 CA CA189,371A patent/CA1014067A/en not_active Expired
- 1974-01-03 DD DD175822A patent/DD111156A5/xx unknown
- 1974-01-03 NO NO740022A patent/NO140578C/en unknown
- 1974-01-03 CH CH3574A patent/CH616930A5/en not_active IP Right Cessation
- 1974-01-03 IE IE10/74A patent/IE38713B1/en unknown
- 1974-01-03 ZA ZA00740061A patent/ZA7461B/en unknown
- 1974-01-03 IL IL43954A patent/IL43954A/en unknown
- 1974-01-03 SE SE7400031A patent/SE430847B/en not_active IP Right Cessation
- 1974-01-04 MW MW1/74*UA patent/MW174A1/en unknown
- 1974-01-04 JP JP450774A patent/JPS5344531B2/ja not_active Expired
- 1974-01-04 NL NLAANVRAGE7400094,A patent/NL183927C/en not_active IP Right Cessation
- 1974-01-05 PH PH7415374A patent/PH12388A/en unknown
- 1974-03-22 CY CY1070A patent/CY1070A/en unknown
- 1974-06-07 ES ES427078A patent/ES427078A1/en not_active Expired
-
1979
- 1979-03-26 CH CH279479A patent/CH628335A5/en not_active IP Right Cessation
- 1979-03-26 CH CH279579A patent/CH616932A5/en not_active IP Right Cessation
- 1979-03-26 CH CH279379A patent/CH616931A5/en not_active IP Right Cessation
-
1980
- 1980-02-21 IT IT8047967A patent/IT8047967A0/en unknown
- 1980-07-12 KE KE3065A patent/KE3065A/en unknown
- 1980-08-14 HK HK442/80A patent/HK44280A/en unknown
-
1981
- 1981-12-30 MY MY146/81A patent/MY8100146A/en unknown
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