IE36607B1 - A propionamide derivative a method of making it and therapeutic compositions containing it - Google Patents
A propionamide derivative a method of making it and therapeutic compositions containing itInfo
- Publication number
- IE36607B1 IE36607B1 IE1058/72A IE105872A IE36607B1 IE 36607 B1 IE36607 B1 IE 36607B1 IE 1058/72 A IE1058/72 A IE 1058/72A IE 105872 A IE105872 A IE 105872A IE 36607 B1 IE36607 B1 IE 36607B1
- Authority
- IE
- Ireland
- Prior art keywords
- acid addition
- addition salts
- making
- compositions containing
- therapeutic compositions
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- QLNJFJADRCOGBJ-UHFFFAOYSA-N propionamide Chemical class CCC(N)=O QLNJFJADRCOGBJ-UHFFFAOYSA-N 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 2
- GOJUJUVQIVIZAV-UHFFFAOYSA-N 2-amino-4,6-dichloropyrimidine-5-carbaldehyde Chemical group NC1=NC(Cl)=C(C=O)C(Cl)=N1 GOJUJUVQIVIZAV-UHFFFAOYSA-N 0.000 abstract 1
- 229910021529 ammonia Inorganic materials 0.000 abstract 1
- 230000003288 anthiarrhythmic effect Effects 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 229940127557 pharmaceutical product Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Pain & Pain Management (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16703171A | 1971-07-28 | 1971-07-28 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE36607L IE36607L (en) | 1973-01-28 |
| IE36607B1 true IE36607B1 (en) | 1976-12-08 |
Family
ID=22605664
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1058/72A IE36607B1 (en) | 1971-07-28 | 1972-07-27 | A propionamide derivative a method of making it and therapeutic compositions containing it |
Country Status (23)
| Country | Link |
|---|---|
| JP (1) | JPS565220B1 (xx) |
| AR (1) | AR193748A1 (xx) |
| AT (1) | AT317185B (xx) |
| AU (1) | AU476000B2 (xx) |
| BE (1) | BE786875A (xx) |
| BR (1) | BR7205069D0 (xx) |
| CA (1) | CA982148A (xx) |
| CH (1) | CH574397A5 (xx) |
| CS (1) | CS171171B2 (xx) |
| DD (1) | DD101389A5 (xx) |
| DK (1) | DK142843B (xx) |
| ES (1) | ES404739A1 (xx) |
| FI (1) | FI55492C (xx) |
| FR (1) | FR2147277B1 (xx) |
| GB (1) | GB1374367A (xx) |
| HU (1) | HU163818B (xx) |
| IE (1) | IE36607B1 (xx) |
| NL (1) | NL176254C (xx) |
| NO (1) | NO137500C (xx) |
| PL (1) | PL84891B1 (xx) |
| SE (1) | SE399702B (xx) |
| SU (1) | SU441704A3 (xx) |
| ZA (1) | ZA724512B (xx) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS57182525U (xx) * | 1981-05-15 | 1982-11-19 | ||
| JPH01128053U (xx) * | 1988-02-24 | 1989-08-31 | ||
| JP2514855B2 (ja) * | 1990-08-08 | 1996-07-10 | キッセイ薬品工業株式会社 | 光学活性なアラニンアニリド誘導体の酸付加塩 |
| GB2267709A (en) * | 1992-06-11 | 1993-12-15 | Merck & Co Inc | Novel process for the preparation of alpha-aminoacylanilides |
| CA3027255C (en) | 2009-07-10 | 2022-06-21 | The General Hospital Corporation | Permanently charged sodium and calcium channel blockers as anti-inflammatory agents |
| DE102012210082A1 (de) * | 2012-06-15 | 2013-12-19 | Hilti Aktiengesellschaft | Werkzeugmaschine und Steuerungsverfahren |
| JP6833811B2 (ja) | 2015-08-03 | 2021-02-24 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 荷電イオンチャネル遮断薬及び使用方法 |
| US11377422B2 (en) | 2019-03-11 | 2022-07-05 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
| US10828287B2 (en) | 2019-03-11 | 2020-11-10 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
| AU2020237474A1 (en) | 2019-03-11 | 2021-09-30 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
| US10780083B1 (en) | 2019-03-11 | 2020-09-22 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
| CA3129089A1 (en) | 2019-03-11 | 2020-09-17 | Bridget Mccarthy Cole | Ester substituted ion channel blockers and methods for use |
| US10933055B1 (en) | 2019-11-06 | 2021-03-02 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
| KR20220123381A (ko) | 2019-11-06 | 2022-09-06 | 녹시온 테라퓨틱스 인코포레이티드 | 하전된 이온 채널 차단제 및 사용 방법 |
| EP4118070A4 (en) | 2020-03-11 | 2024-04-10 | Nocion Therapeutics, Inc. | CHARGED ION CHANNEL BLOCKERS AND METHODS OF USE |
-
0
- BE BE786875D patent/BE786875A/xx not_active IP Right Cessation
-
1972
- 1972-06-30 ZA ZA724512A patent/ZA724512B/xx unknown
- 1972-07-04 CS CS4729A patent/CS171171B2/cs unknown
- 1972-07-04 SE SE7208768A patent/SE399702B/xx unknown
- 1972-07-07 FI FI1945/72A patent/FI55492C/fi active
- 1972-07-11 ES ES404739A patent/ES404739A1/es not_active Expired
- 1972-07-17 CA CA147,247A patent/CA982148A/en not_active Expired
- 1972-07-19 CH CH1080572A patent/CH574397A5/xx not_active IP Right Cessation
- 1972-07-20 GB GB3548172A patent/GB1374367A/en not_active Expired
- 1972-07-20 SU SU1812965A patent/SU441704A3/ru active
- 1972-07-24 DK DK365272AA patent/DK142843B/da not_active IP Right Cessation
- 1972-07-24 AU AU44886/72A patent/AU476000B2/en not_active Expired
- 1972-07-25 AR AR243250A patent/AR193748A1/es active
- 1972-07-25 NO NO2662/72A patent/NO137500C/no unknown
- 1972-07-26 PL PL1972156947A patent/PL84891B1/pl unknown
- 1972-07-27 HU HUAA709A patent/HU163818B/hu unknown
- 1972-07-27 FR FR7227161A patent/FR2147277B1/fr not_active Expired
- 1972-07-27 DD DD164729A patent/DD101389A5/xx unknown
- 1972-07-27 IE IE1058/72A patent/IE36607B1/xx unknown
- 1972-07-28 BR BR5069/72A patent/BR7205069D0/pt unknown
- 1972-07-28 AT AT650472A patent/AT317185B/de active
- 1972-07-28 JP JP7518072A patent/JPS565220B1/ja active Pending
- 1972-07-28 NL NLAANVRAGE7210418,A patent/NL176254C/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| NL176254B (nl) | 1984-10-16 |
| NL7210418A (xx) | 1973-01-30 |
| CA982148A (en) | 1976-01-20 |
| NO137500B (no) | 1977-11-28 |
| GB1374367A (en) | 1974-11-20 |
| IE36607L (en) | 1973-01-28 |
| DK142843B (da) | 1981-02-09 |
| SE399702B (sv) | 1978-02-27 |
| FR2147277B1 (xx) | 1976-04-16 |
| JPS565220B1 (xx) | 1981-02-04 |
| DK142843C (xx) | 1981-08-31 |
| AU4488672A (en) | 1974-01-31 |
| DE2235745B2 (de) | 1976-08-19 |
| AR193748A1 (es) | 1973-05-22 |
| PL84891B1 (en) | 1976-04-30 |
| ZA724512B (en) | 1973-08-29 |
| AU476000B2 (en) | 1976-09-09 |
| NO137500C (no) | 1978-03-08 |
| AT317185B (de) | 1974-08-12 |
| ES404739A1 (es) | 1975-07-16 |
| FI55492B (fi) | 1979-04-30 |
| SU441704A3 (ru) | 1974-08-30 |
| FR2147277A1 (xx) | 1973-03-09 |
| FI55492C (fi) | 1979-08-10 |
| CH574397A5 (xx) | 1976-04-15 |
| DD101389A5 (xx) | 1973-11-05 |
| DE2235745A1 (de) | 1973-02-22 |
| CS171171B2 (xx) | 1976-10-29 |
| BR7205069D0 (pt) | 1973-07-17 |
| HU163818B (xx) | 1973-11-28 |
| NL176254C (nl) | 1985-03-18 |
| BE786875A (fr) | 1973-01-29 |
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