IE36353B1 - Rearrangement of 6-acylamidopenicillanic acid sulfoxides and production fo cephalexin or hetacephalexin - Google Patents

Rearrangement of 6-acylamidopenicillanic acid sulfoxides and production fo cephalexin or hetacephalexin

Info

Publication number
IE36353B1
IE36353B1 IE606/72A IE60672A IE36353B1 IE 36353 B1 IE36353 B1 IE 36353B1 IE 606/72 A IE606/72 A IE 606/72A IE 60672 A IE60672 A IE 60672A IE 36353 B1 IE36353 B1 IE 36353B1
Authority
IE
Ireland
Prior art keywords
acid
hetacephalexin
cephalexin
alkyl
pharmaceutically acceptable
Prior art date
Application number
IE606/72A
Other languages
English (en)
Other versions
IE36353L (en
Inventor
J Rubinfeld
R Lemiuex
R Raap
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of IE36353L publication Critical patent/IE36353L/xx
Publication of IE36353B1 publication Critical patent/IE36353B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/08—Preparation by forming the ring or condensed ring systems
    • C07D501/10—Preparation by forming the ring or condensed ring systems from compounds containing the penicillin ring system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
IE606/72A 1971-05-11 1972-05-08 Rearrangement of 6-acylamidopenicillanic acid sulfoxides and production fo cephalexin or hetacephalexin IE36353B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US00143683A US3843637A (en) 1971-05-11 1971-05-11 Process for rearranging 6-acylamidopenicillanic acid-1-oxides to 7-acyla mido-3-methyl-ceph-3-em-4-carboxylic acids

Publications (2)

Publication Number Publication Date
IE36353L IE36353L (en) 1972-11-11
IE36353B1 true IE36353B1 (en) 1976-10-13

Family

ID=22505135

Family Applications (1)

Application Number Title Priority Date Filing Date
IE606/72A IE36353B1 (en) 1971-05-11 1972-05-08 Rearrangement of 6-acylamidopenicillanic acid sulfoxides and production fo cephalexin or hetacephalexin

Country Status (27)

Country Link
US (1) US3843637A (no)
JP (3) JPS565229B1 (no)
AR (3) AR194364A1 (no)
AT (1) AT325201B (no)
AU (1) AU461358B2 (no)
BE (1) BE783222A (no)
CA (1) CA986096A (no)
CH (1) CH578007A5 (no)
CS (3) CS190399B2 (no)
DD (1) DD99584A5 (no)
DE (1) DE2222953A1 (no)
DK (1) DK140845B (no)
ES (3) ES402672A1 (no)
FI (1) FI58925C (no)
FR (1) FR2143667B1 (no)
GB (1) GB1391838A (no)
HU (2) HU166186B (no)
IE (1) IE36353B1 (no)
IL (1) IL39382A (no)
NL (1) NL7206193A (no)
NO (3) NO146202C (no)
PH (1) PH13518A (no)
PL (3) PL94780B1 (no)
SE (3) SE411045B (no)
SU (2) SU626704A3 (no)
YU (3) YU122672A (no)
ZA (1) ZA723119B (no)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2143211B1 (no) * 1971-06-24 1975-10-31 Fujisawa Pharmaceutical Co
JPS536158B2 (no) * 1972-03-23 1978-03-04
US3960851A (en) * 1972-05-15 1976-06-01 Eli Lilly And Company Preparation of desacetoxy-cephalosporin sulfoxides from penicillin sulfoxides
GB1441587A (en) * 1972-07-14 1976-07-07 Glaxo Lab Ltd Cephalosporin compounds
GB1442785A (en) * 1972-12-09 1976-07-14 Nikken Chemicals Co Ltd Desacetoxy ceaphalosporanic acids
GB1465893A (en) * 1973-02-09 1977-03-02 Gist Brocades Nv I-carboxypropenyl-4-iminothio-azetidine-2-one derivatives methods for their preparation and use
US4010156A (en) * 1973-04-19 1977-03-01 American Home Products Corporation Process for the rearrangement of penicillins to cephalosporins and intermediate compounds thereof
JPS5084591A (no) * 1973-11-29 1975-07-08
US3953440A (en) * 1974-12-13 1976-04-27 Eli Lilly And Company Deacetoxycephalosporins via penicillin sulfoxide rearrangement
US4061862A (en) * 1975-10-06 1977-12-06 Bristol-Myers Company Derivatives of 7-(cyclized)phenylglycyl-3-triazolo-thio methyl cephalosporin
US4091213A (en) * 1975-12-12 1978-05-23 Bristol-Myers Company 7-Cyclizedamino-3-heterothiomethyl cephalosporin derivatives
US4182709A (en) * 1976-01-15 1980-01-08 Glaxo Group Limited Manufacture of semi-synthetic penicillin antibiotics
NO2451643T3 (no) 2009-07-08 2018-01-20

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH565809A5 (no) * 1969-03-11 1975-08-29 Glaxo Lab Ltd

Also Published As

Publication number Publication date
CS190400B2 (en) 1979-05-31
YU174979A (en) 1983-01-21
FR2143667B1 (no) 1977-01-28
SE414177B (sv) 1980-07-14
SE414176B (sv) 1980-07-14
NO146241B (no) 1982-05-18
AR200720A1 (es) 1974-12-13
AR194364A1 (es) 1973-07-13
BE783222A (fr) 1972-11-09
ZA723119B (en) 1973-05-30
YU174879A (en) 1983-02-28
CS190399B2 (en) 1979-05-31
NO146203B (no) 1982-05-10
FI58925C (fi) 1981-05-11
PH13518A (en) 1980-06-03
NO146241C (no) 1982-08-25
FR2143667A1 (no) 1973-02-09
AR197310A1 (es) 1974-03-29
NL7206193A (no) 1972-11-14
JPS565758B2 (no) 1981-02-06
PL85195B1 (no) 1976-04-30
YU122672A (en) 1982-02-28
PL94780B1 (pl) 1977-08-31
CA986096A (en) 1976-03-23
IL39382A0 (en) 1972-07-26
JPS565759B2 (no) 1981-02-06
AT325201B (de) 1975-10-10
DK140845B (da) 1979-11-26
NO146203C (no) 1982-08-18
CS190367B2 (en) 1979-05-31
DD99584A5 (no) 1973-08-12
NO146202C (no) 1982-08-18
FI58925B (fi) 1981-01-30
SU626704A3 (ru) 1978-09-30
SE7414727L (no) 1974-11-22
HU166186B (no) 1975-02-28
HU165177B (no) 1974-07-27
ES402672A1 (es) 1975-10-16
JPS55108875A (en) 1980-08-21
CH578007A5 (no) 1976-07-30
AU4187672A (en) 1973-11-08
PL94030B1 (no) 1977-07-30
ES430117A1 (es) 1976-10-16
GB1391838A (en) 1975-04-23
DE2222953A1 (de) 1973-03-01
AU461358B2 (en) 1975-05-22
ES430116A1 (es) 1976-10-16
SU662013A3 (ru) 1979-05-05
SE411045B (sv) 1979-11-26
IE36353L (en) 1972-11-11
US3843637A (en) 1974-10-22
SE7414728L (no) 1974-11-22
JPS565229B1 (no) 1981-02-04
DK140845C (no) 1980-05-12
NO146202B (no) 1982-05-10
IL39382A (en) 1975-07-28
JPS55108876A (en) 1980-08-21

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